Machilus wangchiana

• Index
• Plant Species
• Metabolite list (14)
• Human Protein
  / Gene in interactions
• Related Diseases

Species

KNApSAcK Entry

Organism name	Machilus wangchiana
Genus	Machilus
Family	Lauraceae
Kingdom	Plantae

---

NCBI taxonomy

Entry

Linked NCBI taxonomy name	Machilus wangchiana
Linked NCBI taxonomy ID	460783
Linked level	species

Family

Family in NCBI taxonomy	Lauraceae
ID	3433

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy	Viridiplantae
ID	33090

Plant class

Plant class	Magnoliophyta
ID	3398

Metabolite list (14)

KNApSAcK ID	name	ChEMBL link	CTD link	# of proteins in ChEMBL interaction / related OMIM / related KEGG DISEASE	# of genes in CTD interaction / related diseases	KCF-S cluster	phytochemical cluster	figure
C00000640	(+)-Eudesmin	CHEMBL519099 CHEMBL512865 CHEMBL523743 CHEMBL464352 CHEMBL1726879	C105875	2 / 0 / 0		No. 38	No. 21
C00000643	Kobusin / (+)-Kobusin / (+)-Spinescin / Methylpiperitol	CHEMBL462822				No. 38	No. 21
C00030703	Machilin I	CHEMBL228326 CHEMBL1170325		1 / 0 / 1		No. 38	No. 21
C00021674	Nectandrin B / Malabaricanol	CHEMBL228326 CHEMBL1170325		1 / 0 / 1		No. 38	No. 21
C00030746	meso-Dihydroguaiaretic acid	CHEMBL430464 CHEMBL375927 CHEMBL1976696		16 / 18 / 12		No. 282	No. 21
C00047968	Lincomolide B	CHEMBL509648				No. 329
C00047929	Isomahubanolide 23	CHEMBL1080352				No. 329
C00047969	Lincomolide C					No. 329
C00037221	Guaiacin / (+)-Guaiacin	CHEMBL482239 CHEMBL1080351				No. 406
C00012727	Costic acid / Costus acid	CHEMBL486398				No. 978
C00047920	Hamabiwalactone A	CHEMBL452992				No. 1362
C00003429	Ginkgolide A	CHEMBL465161 CHEMBL1370614 CHEMBL1408113 CHEMBL1472160 CHEMBL1712596 CHEMBL1741996 CHEMBL2112174		13 / 10 / 12		No. 2137	No. 44
C00035830	Ginkgolide B	CHEMBL514432 CHEMBL1434825 CHEMBL1515002 CHEMBL1898434		17 / 21 / 17		No. 2137	No. 44
C00047666	4-(3-Methoxy-4-hydroxy)phenyl-3-methyl-3-buten-2-one					No. 4323

Human Protein / Gene in interactions

37 ChEMBL Protein in interactions

accession	description	class description	KNApSAcK metabolite in interactions	# of diseases (OMIM / KEGG)
P04150	Glucocorticoid receptor	NR3C1	C00021674 C00030703 C00030746	0 / 1
P10635	Cytochrome P450 2D6	Cytochrome P450 2D6	C00003429 C00035830	1 / 0
P33261	Cytochrome P450 2C19	Cytochrome P450 2C19	C00003429 C00035830	1 / 1
P25105	Platelet-activating factor receptor	PAF receptor	C00003429 C00035830	0 / 0
P05177	Cytochrome P450 1A2	Cytochrome P450 1A2	C00003429 C00035830	0 / 0
P08684	Cytochrome P450 3A4	Cytochrome P450 3A4	C00003429 C00035830	0 / 1
P63092	Guanine nucleotide-binding protein G(s) subunit alpha isoforms short	Other membrane protein	C00030746 C00035830	7 / 3
P11712	Cytochrome P450 2C9	Cytochrome P450 2C9	C00003429 C00035830	0 / 1
P23415	Glycine receptor subunit alpha-1	GLR alpha	C00003429 C00035830	1 / 1
O75496	Geminin	Unclassified protein	C00030746 C00035830	0 / 0
Q92830	Histone acetyltransferase KAT2A	Enzyme	C00000640 C00035830	0 / 0
P23416	Glycine receptor subunit alpha-2	GLR alpha	C00003429 C00035830	0 / 0
P00918	Carbonic anhydrase 2	Lyase	C00030746	1 / 2
P11473	Vitamin D3 receptor	NR1I1	C00035830	2 / 3
P17405	Sphingomyelin phosphodiesterase	Enzyme	C00030746	2 / 2
O75311	Glycine receptor subunit alpha-3	GLR alpha	C00035830	0 / 0
P84022	Mothers against decapentaplegic homolog 3	Unclassified protein	C00030746	2 / 0
P37840	Alpha-synuclein	Unclassified protein	C00030746	4 / 2
Q13526	Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1	Enzyme	C00030746	0 / 0
P00915	Carbonic anhydrase 1	Lyase	C00030746	0 / 0
P43220	Glucagon-like peptide 1 receptor	Glucagon-like peptide receptor	C00030746	0 / 0
P35218	Carbonic anhydrase 5A, mitochondrial	Lyase	C00030746	0 / 0
Q03164	Histone-lysine N-methyltransferase 2A	Enzyme	C00003429	1 / 2
P83916	Chromobox protein homolog 1	Unclassified protein	C00035830	0 / 0
P11021	78 kDa glucose-regulated protein	Unclassified protein	C00003429	0 / 0
Q9Y2D0	Carbonic anhydrase 5B, mitochondrial	Lyase	C00030746	0 / 0
P04062	Glucosylceramidase	Enzyme	C00035830	6 / 4
Q99714	3-hydroxyacyl-CoA dehydrogenase type-2	Enzyme	C00035830	3 / 3
Q99700	Ataxin-2	Unclassified protein	C00030746	1 / 1
Q9UIF8	Bromodomain adjacent to zinc finger domain protein 2B	Unclassified protein	C00003429	0 / 0
Q16637	Survival motor neuron protein	Unclassified protein	C00003429	4 / 1
O75164	Lysine-specific demethylase 4A	Enzyme	C00030746	0 / 0
P27695	DNA-(apurinic or apyrimidinic site) lyase	Enzyme	C00035830	0 / 0
Q16236	Nuclear factor erythroid 2-related factor 2	Unclassified protein	C00030746	0 / 0
Q9UBT6	DNA polymerase kappa	Enzyme	C00000640	0 / 0
O00255	Menin	Unclassified protein	C00003429	2 / 5
Q13148	TAR DNA-binding protein 43	Unclassified protein	C00030746	1 / 1

Related Diseases

Diseases related to proteins in ChEMBL interactions