Papaver somniferum L.

• Index
• Plant Species
• Natural Activity
• Metabolite list (10)
• Human Protein
  / Gene in interactions
• Related Diseases

Species

KNApSAcK Entry

Organism name	Papaver somniferum L.
Genus	Papaver
Family	Papaveraceae
Kingdom	Plantae

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NCBI taxonomy

Entry

Linked NCBI taxonomy name	Papaver somniferum
Linked NCBI taxonomy ID	3469
Linked level	species

Family

Family in NCBI taxonomy	Papaveraceae
ID	3465

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy	Viridiplantae
ID	33090

Plant class

Plant class	eudicotyledons
ID	71240

Natural Activity

List (39)

Species	Activity
Papaver somniferum L.	Abortifacient
Papaver somniferum L.	Analgesic
Papaver somniferum L.	Anaphrodisiac
Papaver somniferum L.	Antibacterial
Papaver somniferum L.	Antidiarrheal
Papaver somniferum L.	Antidote, atropine
Papaver somniferum L.	Antidote, physostigmine
Papaver somniferum L.	Antidote, strychnine
Papaver somniferum L.	Antiinflammatory
Papaver somniferum L.	Antipyretic
Papaver somniferum L.	Antispasmodic
Papaver somniferum L.	Antitussive
Papaver somniferum L.	Aphrodisiac
Papaver somniferum L.	Astringent
Papaver somniferum L.	Calmative
Papaver somniferum L.	Carminative
Papaver somniferum L.	Cerebrostimulant
Papaver somniferum L.	Decongestant
Papaver somniferum L.	Deliriant
Papaver somniferum L.	Demulcent
Papaver somniferum L.	Diaphoretic
Papaver somniferum L.	Diuretic
Papaver somniferum L.	Duphoric
Papaver somniferum L.	Emollient
Papaver somniferum L.	Expectorant
Papaver somniferum L.	Hemostat
Papaver somniferum L.	Hypnotic
Papaver somniferum L.	Hypotensive
Papaver somniferum L.	Intoxicant
Papaver somniferum L.	Lipogenic
Papaver somniferum L.	Myorelaxant
Papaver somniferum L.	Narcotic
Papaver somniferum L.	Nervine
Papaver somniferum L.	Sedative
Papaver somniferum L.	Spinostimulant
Papaver somniferum L.	Stimulant
Papaver somniferum L.	Tonic
Papaver somniferum L.	Tranquilizer
Papaver somniferum L.	Vasodilator

Metabolite list (10)

KNApSAcK ID	name	ChEMBL link	CTD link	# of proteins in ChEMBL interaction / related OMIM / related KEGG DISEASE	# of genes in CTD interaction / related diseases	KCF-S cluster	phytochemical cluster	figure
C00026092	Scoulerine / (-)-Scoulerine	CHEMBL191133 CHEMBL1235966 CHEMBL1395394		27 / 19 / 15		No. 37	No. 4
C00024626	6-Acetonyldihydrosanguinarine / 6-Acetonyl-5,6-dihydrosanguinarine					No. 195	No. 4
C00024657	Norsanguinarine / N-Norsanguinarine / 13-Demethylsanguinarine					No. 254	No. 4
C00025458	Papaverrubine B / O-Methylporphyroxine					No. 305
C00025459	Papaverrubine C / Epiporphyroxine / 14-Epiporphyroxine					No. 305
C00025452	Glaudine					No. 305
C00025461	Papaverrubine E					No. 305
C00025460	Porphyroxine / Papaverrubine D					No. 305
C00025654	Codamine / (+)-Codamine / L-(+)-Codamine / (S)-(+)-Codamine	CHEMBL251624				No. 345	No. 4
C00037598	Xanthaline / Papaveraldine	CHEMBL205040	C039655	15 / 10 / 5		No. 1165	No. 4

Human Protein / Gene in interactions

35 ChEMBL Protein in interactions

accession	description	class description	KNApSAcK metabolite in interactions	# of diseases (OMIM / KEGG)
Q9Y468	Lethal(3)malignant brain tumor-like protein 1	Unclassified protein	C00026092 C00037598	0 / 0
O14727	Apoptotic protease-activating factor 1	Unclassified protein	C00026092 C00037598	0 / 0
Q99700	Ataxin-2	Unclassified protein	C00026092 C00037598	1 / 1
Q9UNA4	DNA polymerase iota	Enzyme	C00026092 C00037598	0 / 0
Q96QE3	ATPase family AAA domain-containing protein 5	Unclassified protein	C00026092 C00037598	0 / 0
Q9Y253	DNA polymerase eta	Enzyme	C00026092 C00037598	1 / 1
P43220	Glucagon-like peptide 1 receptor	Glucagon-like peptide receptor	C00026092 C00037598	0 / 0
P10635	Cytochrome P450 2D6	Cytochrome P450 2D6	C00026092	1 / 0
P11712	Cytochrome P450 2C9	Cytochrome P450 2C9	C00026092	0 / 1
Q9BQF6	Sentrin-specific protease 7	Enzyme	C00037598	0 / 0
Q9GZR1	Sentrin-specific protease 6	Enzyme	C00037598	0 / 0
P14416	D(2) dopamine receptor	Dopamine receptor	C00026092	2 / 0
P39748	Flap endonuclease 1	Enzyme	C00026092	0 / 0
O75496	Geminin	Unclassified protein	C00026092	0 / 0
Q96LD8	Sentrin-specific protease 8	Enzyme	C00037598	0 / 0
P63092	Guanine nucleotide-binding protein G(s) subunit alpha isoforms short	Other membrane protein	C00037598	7 / 3
P02545	Prelamin-A/C	Unclassified protein	C00026092	11 / 10
P42574	Caspase-3	C14	C00037598	0 / 0
Q9HC16	DNA dC->dU-editing enzyme APOBEC-3G	Enzyme	C00026092	0 / 0
O94782	Ubiquitin carboxyl-terminal hydrolase 1	Enzyme	C00026092	0 / 0
P05177	Cytochrome P450 1A2	Cytochrome P450 1A2	C00026092	0 / 0
P29466	Caspase-1	C14	C00026092	0 / 0
P22303	Acetylcholinesterase	Hydrolase	C00037598	1 / 0
P28223	5-hydroxytryptamine receptor 2A	Serotonin receptor	C00026092	0 / 0
P62136	Serine/threonine-protein phosphatase PP1-alpha catalytic subunit	Ser_Thr	C00037598	0 / 0
P33261	Cytochrome P450 2C19	Cytochrome P450 2C19	C00026092	1 / 1
P08684	Cytochrome P450 3A4	Cytochrome P450 3A4	C00026092	0 / 1
P21728	D(1A) dopamine receptor	Dopamine receptor	C00026092	0 / 0
Q9BPW0	Serine/threonine-protein phosphatase	Enzyme	C00037598	0 / 0
Q16236	Nuclear factor erythroid 2-related factor 2	Unclassified protein	C00026092	0 / 0
P08908	5-hydroxytryptamine receptor 1A	Serotonin receptor	C00026092	1 / 0
B2RXH2	Lysine-specific demethylase 4E	Enzyme	C00026092	0 / 0
Q96KQ7	Histone-lysine N-methyltransferase EHMT2	Enzyme	C00026092	0 / 0
O75874	Isocitrate dehydrogenase [NADP] cytoplasmic	Enzyme	C00026092	1 / 0
Q8IUX4	DNA dC->dU-editing enzyme APOBEC-3F	Enzyme	C00026092	0 / 0

Related Diseases

Diseases related to proteins in ChEMBL interactions