| Organism name | Machilus japonica |
|---|---|
| Genus | Machilus |
| Family | Lauraceae |
| Kingdom | Plantae |
| Linked NCBI taxonomy name | Persea japonica |
|---|---|
| Linked NCBI taxonomy ID | 325535 |
| Linked level | species |
| Family in NCBI taxonomy | Lauraceae |
|---|---|
| ID | 3433 |
| Kingdom (Superkingdom) in NCBI taxonomy | Viridiplantae |
|---|---|
| ID | 33090 |
| Plant class | Magnoliophyta |
|---|---|
| ID | 3398 |
| KNApSAcK ID | name | ChEMBL link | CTD link |
# of proteins in
ChEMBL interaction / related OMIM / related KEGG DISEASE |
# of genes in
CTD interaction / related diseases |
KCF-S
cluster |
phytochemical
cluster |
figure |
|---|---|---|---|---|---|---|---|---|
|
C00000697
|
(-)-Machilusin
|
CHEMBL471177
CHEMBL469499 CHEMBL559937 |
No. 38 | No. 21 |
|
|||
|
C00002611
|
Licarin A
/ (-)-Licarin A |
CHEMBL259731
CHEMBL463526 CHEMBL1732407 |
9 / 7 / 3 | No. 215 | No. 23 |
|
||
|
C00047850
|
dl-Coclaurine
|
CHEMBL256448
CHEMBL453291 CHEMBL446211 |
8 / 17 / 10 | No. 253 | No. 4 |
|
||
|
C00007213
|
(-)-Galbacin
|
CHEMBL1980140
CHEMBL2151191 |
2 / 0 / 0 | No. 621 | No. 21 |
|
||
|
C00002605
|
(+)-Galbacin
|
CHEMBL1980140
CHEMBL2151191 |
2 / 0 / 0 | No. 621 | No. 21 |
|
||
|
C00047722
|
Apigenosylide B
/ (+)-Apigenosylide B |
CHEMBL538176
|
No. 4037 |
|
||||
|
C00047723
|
Apigenosylide C
/ (-)-Apigenosylide C |
CHEMBL558750
|
No. 4037 |
|
||||
|
C00047721
|
Apigenosylide A
/ (+)-Apigenosylide A |
CHEMBL540481
|
No. 4037 |
|
| accession | description | class description | KNApSAcK metabolite in interactions |
# of diseases
(OMIM / KEGG) |
|---|---|---|---|---|
| Q16539 | Mitogen-activated protein kinase 14 | p38 | C00002605 C00007213 | 0 / 0 |
| O94925 | Glutaminase kidney isoform, mitochondrial | Enzyme | C00002611 C00047850 | 0 / 0 |
| O75496 | Geminin | Unclassified protein | C00002611 C00047850 | 0 / 0 |
| P45984 | Mitogen-activated protein kinase 9 | Jnk | C00002605 C00007213 | 0 / 0 |
| P43220 | Glucagon-like peptide 1 receptor | Glucagon-like peptide receptor | C00002611 | 0 / 0 |
| P39748 | Flap endonuclease 1 | Enzyme | C00002611 | 0 / 0 |
| P84022 | Mothers against decapentaplegic homolog 3 | Unclassified protein | C00002611 | 2 / 0 |
| P04062 | Glucosylceramidase | Enzyme | C00047850 | 6 / 4 |
| P37840 | Alpha-synuclein | Unclassified protein | C00002611 | 4 / 2 |
| P63092 | Guanine nucleotide-binding protein G(s) subunit alpha isoforms short | Other membrane protein | C00047850 | 7 / 3 |
| Q9UNA4 | DNA polymerase iota | Enzyme | C00002611 | 0 / 0 |
| O75164 | Lysine-specific demethylase 4A | Enzyme | C00002611 | 0 / 0 |
| P10636 | Microtubule-associated protein tau | Unclassified protein | C00047850 | 4 / 3 |
| B2RXH2 | Lysine-specific demethylase 4E | Enzyme | C00047850 | 0 / 0 |
| Q96KQ7 | Histone-lysine N-methyltransferase EHMT2 | Enzyme | C00047850 | 0 / 0 |
| P14618 | Pyruvate kinase PKM | Enzyme | C00047850 | 0 / 0 |
| Q13148 | TAR DNA-binding protein 43 | Unclassified protein | C00002611 | 1 / 1 |
| OMIM | preferred title | UniProt |
|---|---|---|
| #219080 | Acth-independent macronodular adrenal hyperplasia; aimah |
P63092
|
| #612069 | Amyotrophic lateral sclerosis 10, with or without frontotemporal dementia; als10 |
Q13148
|
| #114500 | Colorectal cancer; crc |
P84022
|
| #127750 | Dementia, lewy body; dlb |
P37840
|
| #600274 | Frontotemporal dementia; ftd |
P10636
|
| #608013 | Gaucher disease, perinatal lethal |
P04062
|
| #230800 | Gaucher disease, type i |
P04062
|
| #230900 | Gaucher disease, type ii |
P04062
|
| #231000 | Gaucher disease, type iii |
P04062
|
| #231005 | Gaucher disease, type iiic |
P04062
|
| #613795 | Loeys-dietz syndrome, type 3; lds3 |
P84022
|
| #174800 | Mccune-albright syndrome; mas |
P63092
|
| #166350 | Osseous heteroplasia, progressive; poh |
P63092
|
| #168601 | Parkinson disease 1, autosomal dominant; park1 |
P37840
|
| #605543 | Parkinson disease 4, autosomal dominant; park4 |
P37840
|
| #168600 | Parkinson disease, late-onset; pd |
P04062
P37840 |
| #260540 | Parkinson-dementia syndrome |
P10636
|
| #172700 | Pick disease of brain |
P10636
|
| #102200 | Pituitary adenoma, growth hormone-secreting |
P63092
|
| #103580 | Pseudohypoparathyroidism, type ia; php1a |
P63092
|
| #603233 | Pseudohypoparathyroidism, type ib; php1b |
P63092
|
| #612462 | Pseudohypoparathyroidism, type ic; php1c |
P63092
|
| #601104 | Supranuclear palsy, progressive, 1; psnp1 |
P10636
|
| KEGG | name | UniProt |
|---|---|---|
| H00066 | Lewy body dementia (LBD) |
P04062
(related)
P37840 (related) |
| H00126 | Gaucher disease |
P04062
(related)
|
| H00426 | Defects in the degradation of ganglioside |
P04062
(related)
|
| H00810 | Progressive myoclonic epilepsy (PME) |
P04062
(related)
|
| H00058 | Amyotrophic lateral sclerosis (ALS) |
P10636
(related)
Q13148 (related) |
| H00077 | Progressive supranuclear palsy (PSP) |
P10636
(related)
|
| H00078 | Frontotemporal lobar degeneration (FTLD) |
P10636
(related)
|
| H00057 | Parkinson's disease (PD) |
P37840
(related)
|
| H00244 | Pseudohypoparathyroidism |
P63092
(related)
|
| H00441 | Progressive osseous heteroplasia (POH) |
P63092
(related)
|
| H00501 | Fibrous dysplasia, polyostotic |
P63092
(related)
|