Species

KNApSAcK Entry

Organism name Stephania japonica Miers
Genus Stephania
Family Menispermaceae
Kingdom Plantae

NCBI taxonomy

Entry

Linked NCBI taxonomy name Stephania
Linked NCBI taxonomy ID 147243
Linked level genus

Family

Family in NCBI taxonomy Menispermaceae
ID 3455

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Viridiplantae
ID 33090

Plant class

Plant class eudicotyledons
ID 71240

Metabolite list (26)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE
# of genes in
CTD interaction
/ related diseases
KCF-S
cluster
phytochemical
cluster
figure
C00025660 External link 512 Epistephanine
/ (+)-Epistephanine
CHEMBL2063775
No. 10 No. 4
C00026147 External link 512 Stepinonine
No. 10 No. 4
C00025630 External link 512 Stephanine
/ l-Stephanine
/ (-)-Stephanine
/ (R)-(-)-Stephanine
CHEMBL601020
C054160
1 / 0 / 0 No. 20 No. 4
C00025319 External link 512 Oxoxylopin
/ Oxoxylopine
/ Lanuginosine
CHEMBL389400
1 / 4 / 2 No. 74
C00025340 External link 512 Oxostephanine
CHEMBL521933
No. 74
C00026120 External link 512 Cyclanoline
/ (-)-Cissamine
/ alpha-Cyclanoline
CHEMBL2008127
C060801
No. 234
C00026148 External link 512 Steponine
/ (-)-Steponine
No. 234
C00025118 External link 512 Oxostephamiersine
No. 395
C00025119 External link 512 Oxostephasunoline
No. 395
C00025949 External link 512 N,O-Dimethyloxostephine
No. 395
C00025116 External link 512 Oxoepistephamiersine
No. 395
C00026141 External link 512 Stephamiersine
/ Oxostephamiersine
No. 395
C00025107 External link 512 Epistephamiersine
No. 395
C00025129 External link 512 Stephasunoline
No. 395
C00025128 External link 512 Stephamiersine
No. 395
C00025117 External link 512 Oxostephabenine
/ 16-Oxostephabenine
/ N,O-Dimethyloxostephine benzoate
No. 530
C00025124 External link 512 Stephabenine
/ N,O-Dimethylstephine benzoate
No. 530
C00025112 External link 512 Homostephanoline
No. 559 No. 4
C00025098 External link 512 16-Oxohasubanonine
No. 559 No. 4
C00026040 External link 512 Stebisimine
/ 1,2-Dehydronorepistephanine
No. 1154
C00025120 External link 512 Prometaphanin
/ Prometaphanine
No. 1284
C00026045 External link 512 Stephanaberrine
No. 1284
C00025115 External link 512 Metaphanine
CHEMBL1187163
No. 1284
C00025099 External link 512 16-Oxoprometaphanine
No. 1284
C00025122 External link 512 Prostephanaberrine
No. 2981
C00025127 External link 512 Stephadiamine
No. 6218

Human Protein / Gene in interactions

2 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
P24941 Cyclin-dependent kinase 2 Cdc2 C00025630 0 / 0
P00734 Prothrombin S1A C00025319 4 / 2

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (4)

OMIM preferred title UniProt
#614390 Pregnancy loss, recurrent, susceptibility to, 2; rprgl2 P00734
#613679 Prothrombin deficiency, congenital P00734
#601367 Stroke, ischemic P00734
#188050 Thrombophilia due to thrombin defect; thph1 P00734

KEGG DISEASE (2)

KEGG name UniProt
H00223 Inherited thrombophilia P00734 (related)
H01254 Congenital prothrombin deficiency P00734 (related)