| Organism name | Stephania pierrei Diels(=S.erecta Craib) |
|---|---|
| Genus | Stephania |
| Family | Menispermaceae |
| Kingdom | Plantae |
| Linked NCBI taxonomy name | Stephania |
|---|---|
| Linked NCBI taxonomy ID | 147243 |
| Linked level | genus |
| Family in NCBI taxonomy | Menispermaceae |
|---|---|
| ID | 3455 |
| Kingdom (Superkingdom) in NCBI taxonomy | Viridiplantae |
|---|---|
| ID | 33090 |
| Plant class | eudicotyledons |
|---|---|
| ID | 71240 |
| KNApSAcK ID | name | ChEMBL link | CTD link |
# of proteins in
ChEMBL interaction / related OMIM / related KEGG DISEASE |
# of genes in
CTD interaction / related diseases |
KCF-S
cluster |
phytochemical
cluster |
figure |
|---|---|---|---|---|---|---|---|---|
|
C00025593
|
(-)-2-Norisocepharanthine
/ 2'-Nor-1-epicepharanthine |
CHEMBL476777
CHEMBL505900 |
No. 10 | No. 4 |
|
|||
|
C00025604
|
Cycleanine
/ (-)-Cycleanine |
CHEMBL1711244
CHEMBL1983719 |
C037098
|
7 / 1 / 1 | No. 10 | No. 4 |
|
|
|
C00025634
|
1,2-Dehydroapateline
/ (+)-1,2-Dehydroapateline |
CHEMBL390616
|
No. 10 | No. 4 |
|
|||
|
C00025841
|
Dehatridine
|
No. 10 | No. 4 |
|
||||
|
C00025623
|
Phanostenine
/ (-)-Phanostenine |
CHEMBL515639
|
No. 20 | No. 4 |
|
|||
|
C00025622
|
(-)-Nordicentrine
|
CHEMBL518744
|
No. 20 | No. 4 |
|
|||
|
C00025612
|
(-)-Isolaureline
|
CHEMBL389270
CHEMBL510954 CHEMBL600966 |
No. 20 | No. 4 |
|
|||
|
C00025626
|
Remeroline
/ (R)-Roemeroline / (-)-Roemeroline / N-Methylanolobine |
CHEMBL499835
|
No. 20 | No. 4 |
|
|||
|
C00025812
|
Coclaurine
/ (S)-Coclaurine / (-)-Coclaurine |
CHEMBL256448
CHEMBL453291 CHEMBL446211 |
C004690
|
8 / 17 / 10 | No. 253 | No. 4 |
|
|
|
C00025654
|
Codamine
/ (+)-Codamine / L-(+)-Codamine / (S)-(+)-Codamine |
CHEMBL251624
|
No. 345 | No. 4 |
|
| accession | description | class description | KNApSAcK metabolite in interactions |
# of diseases
(OMIM / KEGG) |
|---|---|---|---|---|
| O75496 | Geminin | Unclassified protein | C00025604 C00025812 | 0 / 0 |
| Q9UNA4 | DNA polymerase iota | Enzyme | C00025604 | 0 / 0 |
| P04062 | Glucosylceramidase | Enzyme | C00025812 | 6 / 4 |
| Q13526 | Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 | Enzyme | C00025604 | 0 / 0 |
| Q99700 | Ataxin-2 | Unclassified protein | C00025604 | 1 / 1 |
| P43220 | Glucagon-like peptide 1 receptor | Glucagon-like peptide receptor | C00025604 | 0 / 0 |
| P63092 | Guanine nucleotide-binding protein G(s) subunit alpha isoforms short | Other membrane protein | C00025812 | 7 / 3 |
| P14618 | Pyruvate kinase PKM | Enzyme | C00025812 | 0 / 0 |
| O75164 | Lysine-specific demethylase 4A | Enzyme | C00025604 | 0 / 0 |
| P10636 | Microtubule-associated protein tau | Unclassified protein | C00025812 | 4 / 3 |
| B2RXH2 | Lysine-specific demethylase 4E | Enzyme | C00025812 | 0 / 0 |
| Q96KQ7 | Histone-lysine N-methyltransferase EHMT2 | Enzyme | C00025812 | 0 / 0 |
| Q8IUX4 | DNA dC->dU-editing enzyme APOBEC-3F | Enzyme | C00025604 | 0 / 0 |
| O94925 | Glutaminase kidney isoform, mitochondrial | Enzyme | C00025812 | 0 / 0 |
| OMIM | preferred title | UniProt |
|---|---|---|
| #219080 | Acth-independent macronodular adrenal hyperplasia; aimah |
P63092
|
| #600274 | Frontotemporal dementia; ftd |
P10636
|
| #608013 | Gaucher disease, perinatal lethal |
P04062
|
| #230800 | Gaucher disease, type i |
P04062
|
| #230900 | Gaucher disease, type ii |
P04062
|
| #231000 | Gaucher disease, type iii |
P04062
|
| #231005 | Gaucher disease, type iiic |
P04062
|
| #174800 | Mccune-albright syndrome; mas |
P63092
|
| #166350 | Osseous heteroplasia, progressive; poh |
P63092
|
| #168600 | Parkinson disease, late-onset; pd |
P04062
|
| #260540 | Parkinson-dementia syndrome |
P10636
|
| #172700 | Pick disease of brain |
P10636
|
| #102200 | Pituitary adenoma, growth hormone-secreting |
P63092
|
| #103580 | Pseudohypoparathyroidism, type ia; php1a |
P63092
|
| #603233 | Pseudohypoparathyroidism, type ib; php1b |
P63092
|
| #612462 | Pseudohypoparathyroidism, type ic; php1c |
P63092
|
| #183090 | Spinocerebellar ataxia 2; sca2 |
Q99700
|
| #601104 | Supranuclear palsy, progressive, 1; psnp1 |
P10636
|
| KEGG | name | UniProt |
|---|---|---|
| H00066 | Lewy body dementia (LBD) |
P04062
(related)
|
| H00126 | Gaucher disease |
P04062
(related)
|
| H00426 | Defects in the degradation of ganglioside |
P04062
(related)
|
| H00810 | Progressive myoclonic epilepsy (PME) |
P04062
(related)
|
| H00058 | Amyotrophic lateral sclerosis (ALS) |
P10636
(related)
|
| H00077 | Progressive supranuclear palsy (PSP) |
P10636
(related)
|
| H00078 | Frontotemporal lobar degeneration (FTLD) |
P10636
(related)
|
| H00244 | Pseudohypoparathyroidism |
P63092
(related)
|
| H00441 | Progressive osseous heteroplasia (POH) |
P63092
(related)
|
| H00501 | Fibrous dysplasia, polyostotic |
P63092
(related)
|
| H00063 | Spinocerebellar ataxia (SCA) |
Q99700
(related)
|