PCIDB

Guatteriopsis hispida

Species

KNApSAcK Entry

Organism name Guatteriopsis hispida
Genus Guatteriopsis
Family Annonaceae
Kingdom Plantae

NCBI taxonomy

Entry

Linked NCBI taxonomy name Guatteriopsis hispida
Linked NCBI taxonomy ID 402570
Linked level species

Family

Family in NCBI taxonomy Annonaceae
ID 22140

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Viridiplantae
ID 33090

Plant class

Plant class Magnoliophyta
ID 3398

Metabolite list (16)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE 		# of genes in
CTD interaction
/ related diseases 		KCF-S
cluster 		phytochemical
cluster 		figure
C00003186 External link 512 beta-Selinene
C087920
No. 151 No. 38
C00003203 External link 512 alpha-Ylangene
No. 333 No. 38
C00003131 External link 512 beta-Farnesene
/ (E)-beta-Farnesene
/ beta-trans-Farnesene
C062671
No. 404 No. 38
C00000805 External link 512 alpha-Pinene
CHEMBL442565
C005451
3 / 3 / 2 0 / 1 No. 476 No. 35
C00000816 External link 512 beta-Pinene
CHEMBL501351
C010789
No. 476 No. 35
C00003110 External link 512 Caryophyllene
/ (E)-Caryophyllene
/ beta-Caryophyllene
/ (-)-(E)-Caryophyllene
/ (E)-beta-Caryophyllene
CHEMBL445740
CHEMBL448700
2 / 3 / 7 No. 478 No. 38
C00021310 External link 512 gamma-Himachalene
No. 478 No. 38
C00029674 External link 512 alpha-Terpineol
CHEMBL447597
CHEMBL449810
C016775
3 / 16 / 11 No. 983 No. 35
C00003147 External link 512 Humulene
/ alpha-Caryophyllene
/ (+/-)-alpha-Humulene
CHEMBL251280
C042686
No. 1421 No. 38
C00007636 External link 512 delta-Cadinene
CHEMBL445759
No. 1524 No. 39
C00021903 External link 512 alpha-trans-Bergamotene
/ trans-alpha-Bergamotene
No. 1653 No. 38
C00012444 External link 512 Humulene oxide II
/ Humulene epoxide II
/ Humulene II epoxide
/ Humulene 6,7-epoxide
/ Humulene 1,2-epoxide
/ (-)-Humulene epoxide II
No. 1728
C00003040 External link 512 p-Cymene
CHEMBL442915
C007210
No. 2172 No. 35
C00000853 External link 512 Myrcene
CHEMBL455491
C008574
3 / 3 / 3 No. 2285 No. 34
C00003029 External link 512 Camphene
CHEMBL506889
CHEMBL510535
C019286
No. 2460 No. 35
C00020383 External link 512 gamma-Gurjunene
/ (+)-gamma-Gurjunene
CHEMBL455046
No. 3712 No. 38

Human Protein / Gene in interactions

10 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
P16473 Thyrotropin receptor Glycohormone receptor C00000805 C00000853 3 / 2
P28482 Mitogen-activated protein kinase 1 Erk C00000805 0 / 0
P22310 UDP-glucuronosyltransferase 1-4 Enzyme C00029674 3 / 0
P04150 Glucocorticoid receptor NR3C1 C00000853 0 / 1
Q96RI1 Bile acid receptor NR1H4 C00000853 0 / 0
P02545 Prelamin-A/C Unclassified protein C00029674 11 / 10
P51449 Nuclear receptor ROR-gamma Nuclear hormone receptor subfamily 1 group F member 3 C00000805 0 / 0
P22309 UDP-glucuronosyltransferase 1-1 Enzyme C00029674 5 / 1
O00255 Menin Unclassified protein C00003110 2 / 5
Q03164 Histone-lysine N-methyltransferase 2A Enzyme C00003110 1 / 2

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (22)

OMIM preferred title UniProt
#601816 Bilirubin, serum level of, quantitative trait locus 1; biliqtl1 P22309
#115200 Cardiomyopathy, dilated, 1a; cmd1a P02545
#212112 Cardiomyopathy, dilated, with hypergonadotropic hypogonadism P02545
#605588 Charcot-marie-tooth disease, axonal, type 2b1; cmt2b1 P02545
#218800 Crigler-najjar syndrome, type i P22309
P22310
#606785 Crigler-najjar syndrome, type ii P22309
P22310
#181350 Emery-dreifuss muscular dystrophy 2, autosomal dominant; edmd2 P02545
#143500 Gilbert syndrome P22309
P22310
#605130 Hairy elbows, short stature, facial dysmorphism, and developmental delay Q03164
#610140 Heart-hand syndrome, slovenian type P02545
#176670 Hutchinson-gilford progeria syndrome; hgps P02545
#237900 Hyperbilirubinemia, transient familial neonatal; hblrtfn P22309
#145000 Hyperparathyroidism 1; hrpt1 O00255
#603373 Hyperthyroidism, familial gestational P16473
#609152 Hyperthyroidism, nonautoimmune P16473
#275200 Hypothyroidism, congenital, nongoitrous, 1; chng1 P16473
#151660 Lipodystrophy, familial partial, type 2; fpld2 P02545
#248370 Mandibuloacral dysplasia with type a lipodystrophy; mada P02545
#131100 Multiple endocrine neoplasia, type i; men1 O00255
#613205 Muscular dystrophy, congenital, lmna-related P02545
#159001 Muscular dystrophy, limb-girdle, type 1b; lgmd1b P02545
#275210 Restrictive dermopathy, lethal P02545

KEGG DISEASE (21)

KEGG name UniProt
H00033 Adrenal carcinoma O00255 (related)
H00034 Carcinoid O00255 (related)
H00045 Malignant islet cell carcinoma O00255 (related)
H00246 Primary hyperparathyroidism O00255 (related)
H01102 Pituitary adenomas O00255 (related)
H00264 Charcot-Marie-Tooth disease (CMT) P02545 (related)
H00294 Dilated cardiomyopathy (DCM) P02545 (related)
H00420 Familial partial lipodystrophy (FPL) P02545 (related)
H00563 Emery-Dreifuss muscular dystrophy P02545 (related)
H00590 Congenital muscular dystrophies (CMD/MDC) P02545 (related)
H00593 Limb-girdle muscular dystrophy (LGMD) P02545 (related)
H00601 Hutchinson-Gilford progeria syndrome P02545 (related)
H00663 Restrictive dermopathy P02545 (related)
H00665 Mandibuloacral dysplasia P02545 (related)
H01216 Left ventricular noncompaction (LVNC) P02545 (related)
H00599 46,XX disorders of sex development (Disorders related to androgen excess) P04150 (related)
H00250 Congenital nongoitrous hypothyroidism (CHNG) P16473 (related)
H01269 Congenital hyperthyroidism P16473 (related)
H00208 Hyperbilirubinemia P22309 (related)
H00001 Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) Q03164 (related)
Q03164 (marker)
H00002 Acute lymphoblastic leukemia (ALL) (precursor T lymphoblastic leukemia) Q03164 (related)

Diseases related to CTD interactions

1 disease in interactions with metabolites

MESH or OMIM name KNApSAcK
metabolite
D003877 Dermatitis, Contact C00000805