Bos taurus domesticus GMELIN

• Index
• Plant Species
• Metabolite list (5)
• Human Protein
  / Gene in interactions
• Related Diseases

Species

KNApSAcK Entry

Organism name	Bos taurus domesticus GMELIN
Genus	Bos
Family	Bovidae
Kingdom	Animalia

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NCBI taxonomy

Entry

Linked NCBI taxonomy name	Bos
Linked NCBI taxonomy ID	9903
Linked level	genus

Family

Family in NCBI taxonomy	Bovidae
ID	9895

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy	Metazoa
ID	33208

Plant class

Plant class
ID

Metabolite list (5)

KNApSAcK ID	name	ChEMBL link	CTD link	# of proteins in ChEMBL interaction / related OMIM / related KEGG DISEASE	# of genes in CTD interaction / related diseases	KCF-S cluster	phytochemical cluster	figure
C00029948	Methyl chlorogenate / Methyl 5-O-caffeoylquinate / Chlorogenic acid methyl ester	CHEMBL416955 CHEMBL596924 CHEMBL1765881 CHEMBL1765882 CHEMBL2048503 CHEMBL2349427		6 / 5 / 4		No. 314	No. 6
C00032464	Ursodeoxycholic acid	CHEMBL156266 CHEMBL240597 CHEMBL1551 CHEMBL1395373 CHEMBL1439625 CHEMBL1520183 CHEMBL1981518 CHEMBL1988085 CHEMBL2074643	D014580	31 / 42 / 36	120 / 39	No. 2182
C00030498	Hyodeoxycholic acid	CHEMBL272620 CHEMBL272621 CHEMBL1473584 CHEMBL2359483	C010471	13 / 14 / 5	2 / 0	No. 2182
C00030117	Deoxycholic acid / 3alpha,12alpha-Dihydroxy-5.beta.-cholanoic acid	CHEMBL348338 CHEMBL412516 CHEMBL410872 CHEMBL406393 CHEMBL1609669 CHEMBL2078862 CHEMBL2092842 CHEMBL2356050	D003840	16 / 7 / 7	44 / 12	No. 2182
C00029828	Bilirubin / (Z,Z)-Bilirubin	CHEMBL501680	D001663	22 / 31 / 28	155 / 20	No. 6732

Human Protein / Gene in interactions

64 ChEMBL Protein in interactions

accession	description	class description	KNApSAcK metabolite in interactions	# of diseases (OMIM / KEGG)
Q13148	TAR DNA-binding protein 43	Unclassified protein	C00030117 C00030498 C00032464	1 / 1
Q8TDU6	G-protein coupled bile acid receptor 1	Steroid-like ligand receptor	C00030117 C00030498 C00032464	0 / 0
P33261	Cytochrome P450 2C19	Cytochrome P450 2C19	C00030117 C00032464	1 / 1
O75795	UDP-glucuronosyltransferase 2B17	Enzyme	C00029828 C00030498	1 / 0
Q9NUW8	Tyrosyl-DNA phosphodiesterase 1	Enzyme	C00029828 C00032464	1 / 1
Q9UBT6	DNA polymerase kappa	Enzyme	C00029828 C00032464	0 / 0
P10636	Microtubule-associated protein tau	Unclassified protein	C00029828 C00030498	4 / 3
O95342	Bile salt export pump	drug	C00030117 C00032464	2 / 1
P22309	UDP-glucuronosyltransferase 1-1	Enzyme	C00029828 C00030498	5 / 1
P08684	Cytochrome P450 3A4	Cytochrome P450 3A4	C00030117 C00032464	0 / 1
O00255	Menin	Unclassified protein	C00029828 C00032464	2 / 5
P06133	UDP-glucuronosyltransferase 2B4	Enzyme	C00030498 C00032464	0 / 0
P05177	Cytochrome P450 1A2	Cytochrome P450 1A2	C00030117 C00032464	0 / 0
Q03164	Histone-lysine N-methyltransferase 2A	Enzyme	C00029828 C00032464	1 / 2
P02545	Prelamin-A/C	Unclassified protein	C00029828 C00032464	11 / 10
Q12908	Ileal sodium/bile acid cotransporter	Bile acid	C00030117 C00032464	1 / 1
P46721	Solute carrier organic anion transporter family member 1A2	Unclassified protein	C00029828 C00032464	0 / 0
O75496	Geminin	Unclassified protein	C00030117 C00032464	0 / 0
P11712	Cytochrome P450 2C9	Cytochrome P450 2C9	C00030117 C00032464	0 / 1
P16662	UDP-glucuronosyltransferase 2B7	Enzyme	C00029828 C00030498	0 / 0
Q14973	Sodium/bile acid cotransporter	Bile acid	C00030117 C00032464	0 / 0
P10635	Cytochrome P450 2D6	Cytochrome P450 2D6	C00030117 C00032464	1 / 0
P11473	Vitamin D3 receptor	NR1I1	C00029828	2 / 3
P00352	Retinal dehydrogenase 1	Enzyme	C00029828	0 / 0
Q9HAW7	UDP-glucuronosyltransferase 1-7	Enzyme	C00030498	0 / 0
P02768	Serum albumin	Secreted protein	C00032464	0 / 0
P10828	Thyroid hormone receptor beta	NR1A2	C00030498	3 / 1
O15439	Multidrug resistance-associated protein 4	Unclassified protein	C00032464	0 / 0
O60656	UDP-glucuronosyltransferase 1-9	Enzyme	C00029828	0 / 0
P54855	UDP-glucuronosyltransferase 2B15	Enzyme	C00030498	0 / 0
P03956	Interstitial collagenase	M10A	C00029948	0 / 1
P63092	Guanine nucleotide-binding protein G(s) subunit alpha isoforms short	Other membrane protein	C00032464	7 / 3
P37840	Alpha-synuclein	Unclassified protein	C00032464	4 / 2
Q9NPD5	Solute carrier organic anion transporter family member 1B3	Electrochemical transporter	C00029828	1 / 0
O94782	Ubiquitin carboxyl-terminal hydrolase 1	Enzyme	C00029828	0 / 0
P04150	Glucocorticoid receptor	NR3C1	C00032464	0 / 1
P45452	Collagenase 3	M10A	C00029948	1 / 1
Q96RI1	Bile acid receptor	NR1H4	C00032464	0 / 0
P18433	Receptor-type tyrosine-protein phosphatase alpha	Receptor tyrosine-protein phosphatase	C00030117	0 / 0
Q13526	Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1	Enzyme	C00030117	0 / 0
P08253	72 kDa type IV collagenase	M10A	C00029948	1 / 3
Q99714	3-hydroxyacyl-CoA dehydrogenase type-2	Enzyme	C00029828	3 / 3
Q92887	Canalicular multispecific organic anion transporter 1	Unclassified protein	C00032464	1 / 1
Q9HAW9	UDP-glucuronosyltransferase 1-8	Enzyme	C00030498	0 / 0
P14780	Matrix metalloproteinase-9	M10A	C00029948	2 / 2
P36537	UDP-glucuronosyltransferase 2B10	Enzyme	C00030498	0 / 0
P23467	Receptor-type tyrosine-protein phosphatase beta	Receptor tyrosine-protein phosphatase	C00030117	0 / 0
P55210	Caspase-7	C14	C00029828	0 / 0
P39900	Macrophage metalloelastase	M10A	C00029948	0 / 0
P29466	Caspase-1	C14	C00029828	0 / 0
P04062	Glucosylceramidase	Enzyme	C00032464	6 / 4
P49798	Regulator of G-protein signaling 4	Unclassified protein	C00032464	2 / 0
P19224	UDP-glucuronosyltransferase 1-6	Enzyme	C00029828	0 / 0
Q16236	Nuclear factor erythroid 2-related factor 2	Unclassified protein	C00030117	0 / 0
P08235	Mineralocorticoid receptor	NR3C2	C00032464	2 / 2
P31939	Bifunctional purine biosynthesis protein PURH	Enzyme	C00030117	1 / 1
P08254	Stromelysin-1	M10A	C00029948	1 / 0
P04054	Phospholipase A2	Enzyme	C00032464	0 / 0
Q9HAW8	UDP-glucuronosyltransferase 1-10	Enzyme	C00030498	0 / 0
B2RXH2	Lysine-specific demethylase 4E	Enzyme	C00029828	0 / 0
Q9Y6L6	Solute carrier organic anion transporter family member 1B1	Electrochemical transporter	C00029828	1 / 0
P22310	UDP-glucuronosyltransferase 1-4	Enzyme	C00029828	3 / 0
O75469	Nuclear receptor subfamily 1 group I member 2	NR1I2	C00032464	0 / 0
P83916	Chromobox protein homolog 1	Unclassified protein	C00032464	0 / 0

285 Gene in CTD interactions

gene	gene name	gene description	KNApSAcK metabolite in interactions
1576	CYP3A4, CP33, CP34, CYP3A, CYP3A3, CYPIIIA3, CYPIIIA4, HLP, NF-25, P450C3, P450PCN1	cytochrome P450, family 3, subfamily A, polypeptide 4 (EC:1.14.13.67 1.14.13.97 1.14.13.32 1.14.13.157)	C00029828 C00030117 C00032464
5594	MAPK1, ERK, ERK2, ERT1, MAPK2, P42MAPK, PRKM1, PRKM2, p38, p40, p41, p41mapk	mitogen-activated protein kinase 1 (EC:2.7.11.24)	C00029828 C00030117 C00032464
5595	MAPK3, ERK-1, ERK1, ERT2, HS44KDAP, HUMKER1A, P44ERK1, P44MAPK, PRKM3, p44-ERK1, p44-MAPK	mitogen-activated protein kinase 3 (EC:2.7.11.24)	C00029828 C00030117 C00032464
595	CCND1, BCL1, D11S287E, PRAD1, U21B31	cyclin D1	C00029828 C00032464
142	PARP1, ADPRT, ADPRT_1, ADPRT1, ARTD1, PARP, PARP-1, PPOL, pADPRT-1	poly (ADP-ribose) polymerase 1 (EC:2.4.2.30)	C00030117 C00032464
9971	NR1H4, BAR, FXR, HRR-1, HRR1, RIP14	nuclear receptor subfamily 1, group H, member 4	C00030117 C00032464
374	AREG, AR, CRDGF, SDGF	amphiregulin	C00029828 C00030117
4790	NFKB1, EBP-1, KBF1, NF-kB1, NF-kappa-B, NF-kappaB, NFKB-p105, NFKB-p50, NFkappaB, p105, p50	nuclear factor of kappa light polypeptide gene enhancer in B-cells 1	C00030117 C00032464
3082	HGF, DFNB39, F-TCF, HGFB, HPTA, SF	hepatocyte growth factor (hepapoietin A; scatter factor)	C00030117 C00032464
9965	FGF19	fibroblast growth factor 19	C00030117 C00032464
2172	FABP6, I-15P, I-BABP, I-BALB, I-BAP, ILBP, ILBP3, ILLBP	fatty acid binding protein 6, ileal	C00030117 C00032464
1956	EGFR, ERBB, ERBB1, HER1, PIG61, mENA	epidermal growth factor receptor (EC:2.7.10.1)	C00030117 C00032464
1581	CYP7A1, CP7A, CYP7, CYPVII	cytochrome P450, family 7, subfamily A, polypeptide 1 (EC:1.14.13.17)	C00030117 C00032464
1051	CEBPB, C/EBP-beta, CRP2, IL6DBP, LAP, LIP, NF-IL6, TCF5	CCAAT/enhancer binding protein (C/EBP), beta	C00030117 C00032464
842	CASP9, APAF-3, APAF3, ICE-LAP6, MCH6, PPP1R56	caspase 9, apoptosis-related cysteine peptidase (EC:3.4.22.62)	C00030117 C00032464
839	CASP6, MCH2	caspase 6, apoptosis-related cysteine peptidase (EC:3.4.22.59)	C00030117 C00032464
5579	PRKCB, PKC-beta, PKCB, PRKCB1, PRKCB2	protein kinase C, beta (EC:2.7.11.13)	C00030117 C00032464
836	CASP3, CPP32, CPP32B, SCA-1	caspase 3, apoptosis-related cysteine peptidase (EC:3.4.22.56)	C00030117 C00032464
596	BCL2, Bcl-2, PPP1R50	B-cell CLL/lymphoma 2	C00030117 C00032464
8647	ABCB11, ABC16, BRIC2, BSEP, PFIC-2, PFIC2, PGY4, SPGP	ATP-binding cassette, sub-family B (MDR/TAP), member 11	C00030117 C00032464
9962	SLC23A2, NBTL1, SLC23A1, SVCT2, YSPL2	solute carrier family 23 (ascorbic acid transporter), member 2	C00029828 C00032464
9963	SLC23A1, SLC23A2, SVCT1, YSPL3	solute carrier family 23 (ascorbic acid transporter), member 1	C00029828 C00032464
22836	RHOBTB3	Rho-related BTB domain containing 3	C00029828 C00032464
10549	PRDX4, AOE37-2, PRX-4	peroxiredoxin 4 (EC:1.11.1.15)	C00029828 C00030117
8856	NR1I2, BXR, ONR1, PAR, PAR1, PAR2, PARq, PRR, PXR, SAR, SXR	nuclear receptor subfamily 1, group I, member 2	C00029828 C00032464
5743	PTGS2, COX-2, COX2, GRIPGHS, PGG/HS, PGHS-2, PHS-2, hCox-2	prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) (EC:1.14.99.1)	C00030117 C00032464
5894	RAF1, CRAF, NS5, Raf-1, c-Raf	v-raf-1 murine leukemia viral oncogene homolog 1 (EC:2.7.11.1)	C00030117 C00032464
3569	IL6, BSF2, HGF, HSF, IFNB2, IL-6	interleukin 6 (interferon, beta 2)	C00029828 C00032464
3309	HSPA5, BIP, GRP78, MIF2	heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)	C00029828 C00030117
3162	HMOX1, HMOX1D, HO-1, HSP32, bK286B10	heme oxygenase (decycling) 1 (EC:1.14.99.3)	C00029828 C00030117
2950	GSTP1, DFN7, FAEES3, GST3, GSTP, PI	glutathione S-transferase pi 1 (EC:2.5.1.18)	C00029828 C00030117
1543	CYP1A1, AHH, AHRR, CP11, CYP1, P1-450, P450-C, P450DX	cytochrome P450, family 1, subfamily A, polypeptide 1 (EC:1.14.14.1)	C00029828 C00032464
207	AKT1, AKT, CWS6, PKB, PKB-ALPHA, PRKBA, RAC, RAC-ALPHA	v-akt murine thymoma viral oncogene homolog 1 (EC:2.7.11.1)	C00029828 C00032464
406991	MIR21, MIRN21, hsa-mir-21, miR-21, miRNA21	microRNA 21	C00032464
1559	CYP2C9, CPC9, CYP2C, CYP2C10, CYPIIC9, P450IIC9	cytochrome P450, family 2, subfamily C, polypeptide 9 (EC:1.14.13.48 1.14.13.49 1.14.13.80)	C00029828
1548	CYP2A6, CPA6, CYP2A, CYP2A3, CYPIIA6, P450C2A, P450PB	cytochrome P450, family 2, subfamily A, polypeptide 6 (EC:1.14.14.1)	C00029828
1649	DDIT3, CEBPZ, CHOP, CHOP-10, CHOP10, GADD153	DNA-damage-inducible transcript 3	C00029828
420357			C00029828
93099	DMKN, UNQ729, ZD52F10	dermokine	C00029828
3337	DNAJB1, HSPF1, Hdj1, Hsp40, RSPH16B, Sis1	DnaJ (Hsp40) homolog, subfamily B, member 1	C00029828
23549	DNPEP, ASPEP, DAP	aspartyl aminopeptidase (EC:3.4.11.21)	C00029828
23333	DPY19L1	dpy-19-like 1 (C. elegans)	C00029828
1847	DUSP5, DUSP, HVH3	dual specificity phosphatase 5 (EC:3.1.3.16 3.1.3.48)	C00029828
54583	EGLN1, C1orf12, ECYT3, HIF-PH2, HIFPH2, HPH-2, HPH2, PHD2, SM20, ZMYND6	egl-9 family hypoxia-inducible factor 1 (EC:1.14.11.29)	C00029828
9538	EI24, EPG4, PIG8, TP53I8	etoposide induced 2.4	C00029828
23741	EID1, C15orf3, CRI1, EID-1, IRO45620, PTD014, RBP21	EP300 interacting inhibitor of differentiation 1	C00029828
9451	EIF2AK3, PEK, PERK, WRS	eukaryotic translation initiation factor 2-alpha kinase 3 (EC:2.7.11.1)	C00029828
1965	EIF2S1, EIF-2, EIF-2A, EIF-2alpha, EIF2, EIF2A	eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa	C00029828
23052	ENDOD1	endonuclease domain containing 1	C00029828
345757	FAM174A, TMEM157, UNQ1912	family with sequence similarity 174, member A	C00029828
8061	FOSL1, FRA, FRA1, fra-1	FOS-like antigen 1	C00029828
4616	GADD45B, GADD45BETA, MYD118	growth arrest and DNA-damage-inducible, beta	C00029828
60674	GAS5, NCRNA00030, SNHG2	growth arrest-specific 5 (non-protein coding)	C00029828
2934	GSN, ADF, AGEL	gelsolin	C00029828
2938	GSTA1, GST2, GSTA1-1, GTH1	glutathione S-transferase alpha 1 (EC:2.5.1.18)	C00029828
2939	GSTA2, GST2, GSTA2-2, GTA2, GTH2	glutathione S-transferase alpha 2 (EC:2.5.1.18)	C00029828
2940	GSTA3, GSTA3-3, GTA3	glutathione S-transferase alpha 3 (EC:2.5.1.18)	C00029828
2941	GSTA4, GSTA4-4, GTA4	glutathione S-transferase alpha 4 (EC:2.5.1.18)	C00029828
373156	GSTK1, GST, GST_13-13, GST13, GST13-13, GSTK1-1, hGSTK1	glutathione S-transferase kappa 1 (EC:2.5.1.18)	C00029828
2944	GSTM1, GST1, GSTM1-1, GSTM1a-1a, GSTM1b-1b, GTH4, GTM1, H-B, MU, MU-1	glutathione S-transferase mu 1 (EC:2.5.1.18)	C00029828
2920	CXCL2, CINC-2a, GRO2, GROb, MGSA-b, MIP-2a, MIP2, MIP2A, SCYB2	chemokine (C-X-C motif) ligand 2	C00029828
9843	HEPH, CPL	hephaestin	C00029828
9709	HERPUD1, HERP, Mif1, SUP	homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1	C00029828
3008	HIST1H1E, H1.4, H1E, H1F4, H1s-4, dJ221C16.5	histone cluster 1, H1e	C00029828
8347	HIST1H2BC, H2B.1, H2B/l, H2BFL, dJ221C16.3	histone cluster 1, H2bc	C00029828
319188			C00029828
8294	HIST1H4I, H4/m, H4FM, H4M	histone cluster 1, H4i	C00029828
97114			C00029828
92815	HIST3H2A	histone cluster 3, H2a	C00029828
6373	CXCL11, H174, I-TAC, IP-9, IP9, SCYB11, SCYB9B, b-R1	chemokine (C-X-C motif) ligand 11	C00029828
373300			C00029828
3627	CXCL10, C7, IFI10, INP10, IP-10, SCYB10, crg-2, gIP-10, mob-1	chemokine (C-X-C motif) ligand 10	C00029828
3418	IDH2, D2HGA2, ICD-M, IDH, IDHM, IDP, IDPM, mNADP-IDH	isocitrate dehydrogenase 2 (NADP+), mitochondrial (EC:1.1.1.42)	C00029828
3475	IFRD1, PC4, TIS7	interferon-related developmental regulator 1	C00029828
3486	IGFBP3, BP-53, IBP3	insulin-like growth factor binding protein 3	C00029828
3606	IL18, IGIF, IL-18, IL-1g, IL1F4	interleukin 18 (interferon-gamma-inducing factor)	C00029828
3553	IL1B, IL-1, IL1-BETA, IL1F2	interleukin 1, beta	C00029828
1512	CTSH, ACC-4, ACC-5, CPSB, minichain	cathepsin H (EC:3.4.22.16)	C00029828
3912	LAMB1, CLM, LIS5	laminin, beta 1	C00029828
3920	LAMP2, CD107b, LAMP-2, LAMPB, LGP110	lysosomal-associated membrane protein 2	C00029828
54741	LEPROT, LEPR, OB-RGRP, OBRGRP, VPS55	leptin receptor overlapping transcript	C00029828
3976	LIF, CDF, DIA, HILDA, MLPLI	leukemia inhibitory factor	C00029828
4035	LRP1, A2MR, APOER, APR, CD91, IGFBP3R, LRP, LRP1A, TGFBR5	low density lipoprotein receptor-related protein 1	C00029828
110454			C00029828
4094	MAF, CCA4, c-MAF	v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog	C00029828
1437	CSF2, GMCSF	colony stimulating factor 2 (granulocyte-macrophage)	C00029828
1362	CPD, GP180	carboxypeptidase D (EC:3.4.17.22)	C00029828
10982	MAPRE2, EB1, EB2, RP1	microtubule-associated protein, RP/EB family, member 2	C00029828
4200	ME2, ODS1	malic enzyme 2, NAD(+)-dependent, mitochondrial (EC:1.1.1.38)	C00029828
1955	MEGF9, EGFL5	multiple EGF-like-domains 9	C00029828
4258	MGST2, GST2, MGST-II	microsomal glutathione S-transferase 2 (EC:2.5.1.18)	C00029828
4322	MMP13, CLG3, MANDP1	matrix metallopeptidase 13 (collagenase 3) (EC:3.4.24.-)	C00029828
10205	MPZL2, EVA, EVA1	myelin protein zero-like 2	C00029828
29074	MRPL18, L18mt, MRP-L18	mitochondrial ribosomal protein L18	C00029828
4811	NID1, NID	nidogen 1	C00029828
23530	NNT, GCCD4	nicotinamide nucleotide transhydrogenase (EC:1.6.1.2)	C00029828
1355	COX15, CEMCOX2	cytochrome c oxidase assembly homolog 15 (yeast)	C00029828
9970	NR1I3, CAR, CAR1, MB67	nuclear receptor subfamily 1, group I, member 3	C00029828
29948	OSGIN1, BDGI, OKL38	oxidative stress induced growth inhibitor 1	C00029828
5163	PDK1	pyruvate dehydrogenase kinase, isozyme 1 (EC:2.7.11.2)	C00029828
27315	PGAP2, CWH43-N, FRAG1, HPMRS3, MRT17, MRT21	post-GPI attachment to proteins 2	C00029828
5245	PHB, PHB1	prohibitin	C00029828
8554	PIAS1, DDXBP1, GBP, GU/RH-II, ZMIZ3	protein inhibitor of activated STAT, 1	C00029828
5295	PIK3R1, AGM7, GRB1, p85, p85-ALPHA	phosphoinositide-3-kinase, regulatory subunit 1 (alpha)	C00029828
18722			C00029828
51365	PLA1A, PS-PLA1, PSPLA1	phospholipase A1 member A (EC:3.1.1.-)	C00029828
5376	PMP22, CMT1A, CMT1E, DSS, GAS-3, HMSNIA, HNPP, Sp110	peripheral myelin protein 22	C00029828
5445	PON2	paraoxonase 2 (EC:3.1.1.2 3.1.1.81)	C00029828
1281	COL3A1, EDS4A	collagen, type III, alpha 1	C00029828
5728	PTEN, 10q23del, BZS, CWS1, DEC, GLM2, MHAM, MMAC1, PTEN1, TEP1	phosphatase and tensin homolog (EC:3.1.3.67 3.1.3.16 3.1.3.48)	C00029828
401494	PTPLAD2, HACD4	protein tyrosine phosphatase-like A domain containing 2 (EC:4.2.1.134)	C00029828
83937	RASSF4, AD037	Ras association (RalGDS/AF-6) domain family member 4	C00029828
9584	RBM39, CAPER, CAPERalpha, FSAP59, HCC1, RNPC2	RNA binding motif protein 39	C00029828
10181	RBM5, G15, LUCA15, RMB5	RNA binding motif protein 5	C00029828
6249	CLIP1, CLIP, CLIP-170, CLIP170, CYLN1, RSN	CAP-GLY domain containing linker protein 1	C00029828
6038	RNASE4, RNS4	ribonuclease, RNase A family, 4 (EC:3.1.27.-)	C00029828
6281	S100A10, 42C, ANX2L, ANX2LG, CAL1L, CLP11, Ca[1], GP11, P11, p10	S100 calcium binding protein A10	C00029828
6275	S100A4, 18A2, 42A, CAPL, FSP1, MTS1, P9KA, PEL98	S100 calcium binding protein A4	C00029828
6342	SCP2, NLTP, NSL-TP, SCP-2, SCP-CHI, SCP-X, SCPX	sterol carrier protein 2 (EC:2.3.1.176)	C00029828
8991	SELENBP1, LPSB, SBP56, SP56, hSBP	selenium binding protein 1	C00029828
66222			C00029828
5054	SERPINE1, PAI, PAI-1, PAI1, PLANH1	serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1	C00029828
27244	SESN1, PA26, SEST1	sestrin 1	C00029828
81537	SGPP1, SPPase1	sphingosine-1-phosphate phosphatase 1	C00029828
387700	SLC16A12, CJMG, MCT12	solute carrier family 16, member 12	C00029828
23155	CLCC1, MCLC	chloride channel CLIC-like 1	C00029828
1119	CHKA, CHK, CK, CKI, EK	choline kinase alpha (EC:2.7.1.32 2.7.1.82)	C00029828
6520	SLC3A2, 4F2, 4F2HC, 4T2HC, CD98, CD98HC, MDU1, NACAE	solute carrier family 3 (amino acid transporter heavy chain), member 2	C00029828
23657	SLC7A11, CCBR1, xCT	solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11	C00029828
10599	SLCO1B1, HBLRR, LST-1, LST1, OATP-C, OATP1B1, OATP2, OATPC, SLC21A6	solute carrier organic anion transporter family, member 1B1	C00029828
57231	SNX14, RGS-PX2	sorting nexin 14	C00029828
50964	SOST, CDD, VBCH	sclerostin	C00029828
389058	SP5	Sp5 transcription factor	C00029828
73526			C00029828
6892	TAPBP, NGS17, TAPA, TPN, TPSN	TAP binding protein (tapasin)	C00029828
6925	TCF4, E2-2, ITF-2, ITF2, PTHS, SEF-2, SEF2, SEF2-1, SEF2-1A, SEF2-1B, TCF-4, bHLHb19	transcription factor 4	C00029828
25976	TIPARP, ARTD14, PARP7, pART14	TCDD-inducible poly(ADP-ribose) polymerase (EC:2.4.2.30)	C00029828
9375	TM9SF2, P76	transmembrane 9 superfamily member 2	C00029828
55504	TNFRSF19, TAJ, TAJ-alpha, TRADE, TROY	tumor necrosis factor receptor superfamily, member 19	C00029828
1200	TPP1, CLN2, LPIC, TPP-1	tripeptidyl peptidase I (EC:3.4.14.9)	C00029828
28951	TRIB2, C5FW, GS3955, TRB2	tribbles pseudokinase 2	C00029828
7329	UBE2I, C358B7.1, P18, UBC9	ubiquitin-conjugating enzyme E2I (EC:6.3.2.19)	C00029828
54658	UGT1A1, BILIQTL1, GNT1, HUG-BR1, UDPGT, UDPGT_1-1, UGT1, UGT1A	UDP glucuronosyltransferase 1 family, polypeptide A1 (EC:2.4.1.17)	C00029828
54659	UGT1A3, UDPGT, UDPGT_1-3, UGT-1C, UGT1-03, UGT1.3, UGT1C	UDP glucuronosyltransferase 1 family, polypeptide A3 (EC:2.4.1.17)	C00029828
7366	UGT2B15, HLUG4, UDPGT_2B8, UDPGT2B15, UDPGTH3, UGT2B8	UDP glucuronosyltransferase 2 family, polypeptide B15 (EC:2.4.1.17)	C00029828
708396			C00029828
7381	UQCRB, MC3DN3, QCR7, QP-C, QPC, UQBC, UQBP, UQCR6, UQPC	ubiquinol-cytochrome c reductase binding protein (EC:1.10.2.2)	C00029828
7384	UQCRC1, D3S3191, QCR1, UQCR1	ubiquinol-cytochrome c reductase core protein I (EC:1.10.2.2)	C00029828
7388	UQCRH, QCR6, UQCR8	ubiquinol-cytochrome c reductase hinge protein (EC:1.10.2.2)	C00029828
80146	UXS1, SDR6E1, UGD	UDP-glucuronate decarboxylase 1 (EC:4.1.1.35)	C00029828
7436	VLDLR, CARMQ1, CHRMQ1, VLDLRCH	very low density lipoprotein receptor	C00029828
26137	ZBTB20, DPZF, HOF, ODA-8S, ZNF288	zinc finger and BTB domain containing 20	C00029828
339487	ZBTB8OS, ARCH, ARCH2	zinc finger and BTB domain containing 8 opposite strand	C00029828
84186	ZCCHC7, AIR1, RP11-397D12.1	zinc finger, CCHC domain containing 7	C00029828
90637	ZFAND2A, AIRAP	zinc finger, AN1-type domain 2A	C00029828
22680			C00029828
24132			C00029828
79094	CHAC1	ChaC, cation transport regulator homolog 1 (E. coli)	C00029828
8714	ABCC3, ABC31, EST90757, MLP2, MOAT-D, MRP3, cMOAT2	ATP-binding cassette, sub-family C (CFTR/MRP), member 3	C00030117
9936	CD302, BIMLEC, CLEC13A, DCL-1, DCL1	CD302 molecule	C00029828
664	BNIP3, NIP3	BCL2/adenovirus E1B 19kDa interacting protein 3	C00030117
25819	CCRN4L, CCR4L, NOC	CCR4 carbon catabolite repression 4-like (S. cerevisiae)	C00029828
151887	CCDC80, DRO1, SSG1, URB, okuribin	coiled-coil domain containing 80	C00029828
847	CAT	catalase (EC:1.11.1.6)	C00029828
10438	C1D, LRP1, SUN-CoR, SUNCOR, hC1D	C1D nuclear receptor corepressor	C00029828
2647	BLOC1S1, BLOS1, GCN5L1, MICoA, RT14	biogenesis of lysosomal organelles complex-1, subunit 1	C00029828
8313	AXIN2, AXIL, ODCRCS	axin 2	C00029828
476	ATP1A1	ATPase, Na+/K+ transporting, alpha 1 polypeptide (EC:3.6.3.9)	C00029828
467	ATF3	activating transcription factor 3	C00029828
2978	GUCA1A, C6orf131, COD3, CORD14, GCAP, GCAP1, GUCA, GUCA1, dJ139D8.6	guanylate cyclase activator 1A (retina)	C00030117
79754	ASB13	ankyrin repeat and SOCS box containing 13	C00029828
3265	HRAS, C-BAS/HAS, C-H-RAS, C-HA-RAS1, CTLO, H-RASIDX, HAMSV, HRAS1, K-RAS, N-RAS, RASH1	Harvey rat sarcoma viral oncogene homolog	C00030117
5654	HTRA1, ARMD7, CARASIL, HtrA, L56, ORF480, PRSS11	HtrA serine peptidase 1 (EC:3.4.21.-)	C00030117
4000	LMNA, CDCD1, CDDC, CMD1A, CMT2B1, EMD2, FPL, FPLD, FPLD2, HGPS, IDC, LDP1, LFP, LGMD1B, LMN1, LMNC, LMNL1, PRO1	lamin A/C	C00030117
4671	NAIP, BIRC1, NLRB1, psiNAIP	NLR family, apoptosis inhibitory protein	C00030117
9411	ARHGAP29, PARG1, RP11-255E17.1	Rho GTPase activating protein 29	C00029828
4792	NFKBIA, IKBA, MAD-3, NFKBI	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha	C00030117
301	ANXA1, ANX1, LPC1	annexin A1	C00029828
4893	NRAS, ALPS4, N-ras, NRAS1, NS6	neuroblastoma RAS viral (v-ras) oncogene homolog	C00030117
210	ALAD, ALADH, PBGS	aminolevulinate dehydratase (EC:4.2.1.24)	C00029828
23396	PIP5K1C, LCCS3, PIP5K-GAMMA, PIP5Kgamma, PIPKIg_v4	phosphatidylinositol-4-phosphate 5-kinase, type I, gamma (EC:2.7.1.68)	C00030117
7001	PRDX2, NKEF-B, NKEFB, PRP, PRX2, PRXII, PTX1, TDPX1, TPX1, TSA	peroxiredoxin 2 (EC:1.11.1.15)	C00030117
5564	PRKAB1, AMPK, HAMPKb	protein kinase, AMP-activated, beta 1 non-catalytic subunit	C00030117
7363	UGT2B4, HLUG25, UDPGT2B4, UDPGTH1, UGT2B11	UDP glucuronosyltransferase 2 family, polypeptide B4 (EC:2.4.1.17)	C00030498
5581	PRKCE, PKCE, nPKC-epsilon	protein kinase C, epsilon (EC:2.7.11.13)	C00030117
5590	PRKCZ, PKC-ZETA, PKC2	protein kinase C, zeta (EC:2.7.11.13)	C00030117
4363	ABCC1, ABC29, ABCC, GS-X, MRP, MRP1	ATP-binding cassette, sub-family C (CFTR/MRP), member 1	C00029828
7364	UGT2B7, UDPGT_2B9, UDPGT2B7, UDPGTH2, UGT2B9	UDP glucuronosyltransferase 2 family, polypeptide B7 (EC:2.4.1.17)	C00030498
5970	RELA, NFKB3, p65	v-rel avian reticuloendotheliosis viral oncogene homolog A	C00030117
5268	SERPINB5, PI5, maspin	serpin peptidase inhibitor, clade B (ovalbumin), member 5	C00030117
200931	SLC51A, OSTA, OSTalpha	solute carrier family 51, alpha subunit	C00030117
123264	SLC51B, OSTB, OSTBETA	solute carrier family 51, beta subunit	C00030117
7186	TRAF2, MGC:45012, TRAP, TRAP3	TNF receptor-associated factor 2	C00030117
5243	ABCB1, ABC20, CD243, CLCS, GP170, MDR1, P-GP, PGY1	ATP-binding cassette, sub-family B (MDR/TAP), member 1 (EC:3.6.3.44)	C00032464
1244	ABCC2, ABC30, CMOAT, DJS, MRP2, cMRP	ATP-binding cassette, sub-family C (CFTR/MRP), member 2	C00032464
1645	AKR1C1, 2-ALPHA-HSD, 20-ALPHA-HSD, C9, DD1, DD1/DD2, DDH, DDH1, H-37, HAKRC, HBAB, MBAB	aldo-keto reductase family 1, member C1 (EC:1.3.1.20 1.1.1.149 1.1.1.112)	C00032464
1646	AKR1C2, AKR1C-pseudo, BABP, DD, DD2, DDH2, HAKRD, HBAB, MCDR2, SRXY8	aldo-keto reductase family 1, member C2 (EC:1.3.1.20 1.1.1.357)	C00032464
8644	AKR1C3, DD3, DDX, HA1753, HAKRB, HAKRe, HSD17B5, PGFS, hluPGFS	aldo-keto reductase family 1, member C3 (EC:1.3.1.20 1.1.1.188 1.1.1.239 1.1.1.64 1.1.1.112 1.1.1.357)	C00032464
23243	ANKRD28, PITK, PPP1R65	ankyrin repeat domain 28	C00032464
1173	AP2M1, AP50, CLAPM1, mu2	adaptor-related protein complex 2, mu 1 subunit	C00032464
335	APOA1	apolipoprotein A-I	C00032464
55937	APOM, G3a, HSPC336, NG20, apo-M	apolipoprotein M	C00032464
581	BAX, BCL2L4	BCL2-associated X protein	C00032464
644	BLVRA, BLVR, BVR, BVRA	biliverdin reductase A (EC:1.3.1.24)	C00032464
722	C4BPA, C4BP, PRP	complement component 4 binding protein, alpha	C00032464
840	CASP7, CASP-7, CMH-1, ICE-LAP3, LICE2, MCH3	caspase 7, apoptosis-related cysteine peptidase (EC:3.4.22.60)	C00032464
841	CASP8, ALPS2B, CAP4, Casp-8, FLICE, MACH, MCH5	caspase 8, apoptosis-related cysteine peptidase (EC:3.4.22.61)	C00032464
6347	CCL2, GDCF-2, HC11, HSMCR30, MCAF, MCP-1, MCP1, SCYA2, SMC-CF	chemokine (C-C motif) ligand 2	C00032464
6352	CCL5, D17S136E, RANTES, SCYA5, SIS-delta, SISd, TCP228, eoCP	chemokine (C-C motif) ligand 5	C00032464
896	CCND3	cyclin D3	C00032464
7203	CCT3, CCT-gamma, CCTG, PIG48, TCP-1-gamma, TRIC5	chaperonin containing TCP1, subunit 3 (gamma)	C00032464
22948	CCT5, CCT-epsilon, CCTE, TCP-1-epsilon	chaperonin containing TCP1, subunit 5 (epsilon)	C00032464
57124	CD248, CD164L1, TEM1	CD248 molecule, endosialin	C00032464
8837	CFLAR, CASH, CASP8AP1, CLARP, Casper, FLAME, FLAME-1, FLAME1, FLIP, I-FLICE, MRIT, c-FLIP, c-FLIPL, c-FLIPR, c-FLIPS	CASP8 and FADD-like apoptosis regulator	C00032464
1267	CNP, CNP1	2',3'-cyclic nucleotide 3' phosphodiesterase (EC:3.1.4.37)	C00032464
1434	CSE1L, CAS, CSE1, XPO2	CSE1 chromosome segregation 1-like (yeast)	C00032464
1464	CSPG4, HMW-MAA, MCSP, MCSPG, MEL-CSPG, MSK16, NG2	chondroitin sulfate proteoglycan 4	C00032464
7818	DAP3, DAP-3, MRP-S29, MRPS29, bMRP-10	death associated protein 3	C00032464
1660	DHX9, DDX9, LKP, NDH2, NDHII, RHA	DEAH (Asp-Glu-Ala-His) box helicase 9 (EC:3.6.4.13)	C00032464
1737	DLAT, DLTA, PDC-E2, PDCE2	dihydrolipoamide S-acetyltransferase (EC:2.3.1.12)	C00032464
10395	DLC1, ARHGAP7, HP, STARD12, p122-RhoGAP	deleted in liver cancer 1	C00032464
1906	EDN1, ET1, HDLCQ7, PPET1	endothelin 1	C00032464
1907	EDN2, ET2, PPET2	endothelin 2	C00032464
10209	EIF1, A121, EIF-1, EIF1A, ISO1, SUI1	eukaryotic translation initiation factor 1	C00032464
2033	EP300, KAT3B, RSTS2, p300	E1A binding protein p300 (EC:2.3.1.48)	C00032464
79956	ERMP1, FXNA, KIAA1815, bA207C16.3	endoplasmic reticulum metallopeptidase 1	C00032464
8772	FADD, MORT1	Fas (TNFRSF6)-associated via death domain	C00032464
26049	FAM169A, SLAP75	family with sequence similarity 169, member A	C00032464
54537	FAM35A, FAM35A1, bA163M19.1	family with sequence similarity 35, member A	C00032464
2266	FGG	fibrinogen gamma chain	C00032464
2267	FGL1, HFREP1, HP-041, LFIRE-1, LFIRE1	fibrinogen-like 1	C00032464
2617	GARS, CMT2D, DSMAV, GlyRS, HMN5, SMAD1	glycyl-tRNA synthetase (EC:6.1.1.14)	C00032464
2729	GCLC, GCL, GCS, GLCL, GLCLC	glutamate-cysteine ligase, catalytic subunit (EC:6.3.2.2)	C00032464
2730	GCLM, GLCLR	glutamate-cysteine ligase, modifier subunit (EC:6.3.2.2)	C00032464
100119944			C00032464
2937	GSS, GSHS	glutathione synthetase (EC:6.3.2.3)	C00032464
3122	HLA-DRA, HLA-DRA1, MLRW	major histocompatibility complex, class II, DR alpha	C00032464
6927	HNF1A, HNF-1A, HNF1, IDDM20, LFB1, MODY3, TCF-1, TCF1	HNF1 homeobox A	C00032464
6928	HNF1B, FJHN, HNF-1B, HNF1beta, HNF2, HPC11, LF-B3, LFB3, MODY5, TCF-2, TCF2, VHNF1	HNF1 homeobox B	C00032464
3385	ICAM3, CD50, CDW50, ICAM-R	intercellular adhesion molecule 3	C00032464
3458	IFNG, IFG, IFI	interferon, gamma	C00032464
3576	IL8, CXCL8, GCP-1, GCP1, LECT, LUCT, LYNAP, MDNCF, MONAP, NAF, NAP-1, NAP1	interleukin 8	C00032464
3615	IMPDH2, IMPD2, IMPDH-II	IMP (inosine 5'-monophosphate) dehydrogenase 2 (EC:1.1.1.205)	C00032464
3713	IVL	involucrin	C00032464
4155	MBP	myelin basic protein	C00032464
4170	MCL1, BCL2L3, EAT, MCL1-ES, MCL1L, MCL1S, Mcl-1, TM, bcl2-L-3, mcl1/EAT	myeloid cell leukemia sequence 1 (BCL2-related)	C00032464
4193	MDM2, ACTFS, HDMX, hdm2	MDM2 oncogene, E3 ubiquitin protein ligase	C00032464
1555	CYP2B6, CPB6, CYP2B, CYP2B7, CYP2B7P, CYPIIB6, EFVM, IIB1, P450	cytochrome P450, family 2, subfamily B, polypeptide 6 (EC:1.14.14.1)	C00029828
4673	NAP1L1, NAP1, NAP1L, NRP	nucleosome assembly protein 1-like 1	C00032464
283131	NEAT1, LINC00084, NCRNA00084, TncRNA, VINC	nuclear paraspeckle assembly transcript 1 (non-protein coding)	C00032464
4780	NFE2L2, NRF2	nuclear factor, erythroid 2-like 2	C00032464
8431	NR0B2, SHP, SHP1	nuclear receptor subfamily 0, group B, member 2	C00032464
220323	OAF, NS5ATP13TP2	OAF homolog (Drosophila)	C00032464
5005	ORM2, AGP-B, AGP-B', AGP2	orosomucoid 2	C00032464
5580	PRKCD, MAY1, PKCD, nPKC-delta	protein kinase C, delta (EC:2.7.10.2 2.7.11.13)	C00032464
5879	RAC1, Rac-1, TC-25, p21-Rac1	ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)	C00032464
5925	RB1, OSRC, RB, p105-Rb, pRb, pp110	retinoblastoma 1	C00032464
5930	RBBP6, MY038, P2P-R, PACT, RBQ-1, SNAMA	retinoblastoma binding protein 6	C00032464
117584	RFFL, CARP-2, CARP2, FRING, RIFIFYLIN, RNF189, RNF34L	ring finger and FYVE-like domain containing E3 ubiquitin protein ligase	C00032464
387	RHOA, ARH12, ARHA, RHO12, RHOH12	ras homolog family member A	C00032464
8737	RIPK1, RIP, RIP1	receptor (TNFRSF)-interacting serine-threonine kinase 1 (EC:2.7.11.1)	C00032464
6134	RPL10, AUTSX5, DXS648, DXS648E, L10, NOV, QM	ribosomal protein L10	C00032464
6155	RPL27, L27	ribosomal protein L27 (EC:3.6.5.3)	C00032464
6161	RPL32, L32	ribosomal protein L32	C00032464
6165	RPL35A, DBA5, L35A	ribosomal protein L35a	C00032464
116832	RPL39L, RPL39L1	ribosomal protein L39-like	C00032464
6128	RPL6, L6, SHUJUN-2, TAXREB107, TXREB1	ribosomal protein L6	C00032464
6181	RPLP2, D11S2243E, LP2, P2, RPP2	ribosomal protein, large, P2	C00032464
6207	RPS13, S13	ribosomal protein S13 (EC:3.6.5.3)	C00032464
51065	RPS27L	ribosomal protein S27-like	C00032464
6234	RPS28, S28	ribosomal protein S28	C00032464
145767			C00032464
55095	SAMD4B, SMGB, hSmaug2	sterile alpha motif domain containing 4B	C00032464
23451	SF3B1, Hsh155, MDS, PRP10, PRPF10, SAP155, SF3b155	splicing factor 3b, subunit 1, 155kDa	C00032464
292	SLC25A5, 2F1, AAC2, ANT2, T2, T3	solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5	C00032464
6522	SLC4A2, AE2, BND3L, EPB3L1, HKB3, NBND3	solute carrier family 4 (anion exchanger), member 2	C00032464
81848	SPRY4, HH17	sprouty homolog 4 (Drosophila)	C00032464
6742	SSBP1, Mt-SSB, SOSS-B1, SSBP, mtSSB	single-stranded DNA binding protein 1, mitochondrial	C00032464
6772	STAT1, CANDF7, ISGF-3, STAT91	signal transducer and activator of transcription 1, 91kDa	C00032464
6788	STK3, KRS1, MST2	serine/threonine kinase 3 (EC:2.7.11.1)	C00032464
7124	TNF, DIF, TNF-alpha, TNFA, TNFSF2	tumor necrosis factor	C00032464
7128	TNFAIP3, A20, OTUD7C, TNFA1P2	tumor necrosis factor, alpha-induced protein 3 (EC:3.4.19.12)	C00032464
8795	TNFRSF10B, CD262, DR5, KILLER, KILLER/DR5, TRAIL-R2, TRAILR2, TRICK2, TRICK2A, TRICK2B, TRICKB, ZTNFR9	tumor necrosis factor receptor superfamily, member 10b	C00032464
7157	TP53, BCC7, LFS1, P53, TRP53	tumor protein p53	C00032464
55339	WDR33, NET14, WDC146	WD repeat domain 33	C00032464

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