PCIDB

Conyza canadensis

Species

KNApSAcK Entry

Organism name Conyza canadensis
Genus Conyza
Family Asteraceae
Kingdom Plantae

NCBI taxonomy

Entry

Linked NCBI taxonomy name Conyza canadensis
Linked NCBI taxonomy ID 72917
Linked level species

Family

Family in NCBI taxonomy Asteraceae
ID 4210

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Viridiplantae
ID 33090

Plant class

Plant class asterids
ID 71274

Natural Activity

List (13)

Species Activity
Conyza canadensis (L.) Cronquist Anthelmintic
Conyza canadensis (L.) Cronquist Antiaggregant
Conyza canadensis (L.) Cronquist Anticonvulsant
Conyza canadensis (L.) Cronquist Antiedemic
Conyza canadensis (L.) Cronquist Antiinflammatory
Conyza canadensis (L.) Cronquist Antioxidant
Conyza canadensis (L.) Cronquist Astringent
Conyza canadensis (L.) Cronquist Diuretic
Conyza canadensis (L.) Cronquist Hemostat
Conyza canadensis (L.) Cronquist Hypotensive
Conyza canadensis (L.) Cronquist Sternutatory
Conyza canadensis (L.) Cronquist Sudorific
Conyza canadensis (L.) Cronquist Tonic

Metabolite list (5)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE 		# of genes in
CTD interaction
/ related diseases 		KCF-S
cluster 		phytochemical
cluster 		figure
C00019065 External link 512 Erythrodiol
/ 3beta-Erythrodiol
CHEMBL298604
CHEMBL60687
CHEMBL400074
C077953
4 / 0 / 1 No. 13 No. 51
C00016318 External link 512 5-Carboxyresorcinol
/ alpha-Resorcylic acid
/ 3,5-Dihydroxybenzoic acid
/ 3,5-Dihydroxy-benzoic acid
CHEMBL95308
C076950
10 / 2 / 4 No. 817 No. 81
C00000856 External link 512 4-Hydroxybenzoic acid
/ p-Hydroxybenzoic acid
CHEMBL441343
C038193
21 / 7 / 16 2 / 1 No. 817 No. 81
C00001287 External link 512 Lachnophyllum ester
No. 979
C00002674 External link 512 Syringic acid
/ 4-Hydroxy-3,5-dimethoxybenzoic acid
CHEMBL1414
C001945
12 / 3 / 5 No. 1073

Human Protein / Gene in interactions

28 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
O43570 Carbonic anhydrase 12 Lyase C00000856 C00002674 C00016318 1 / 2
Q16790 Carbonic anhydrase 9 Lyase C00000856 C00002674 C00016318 0 / 1
P00915 Carbonic anhydrase 1 Lyase C00000856 C00002674 C00016318 0 / 0
Q9ULX7 Carbonic anhydrase 14 Lyase C00000856 C00002674 C00016318 0 / 0
P00918 Carbonic anhydrase 2 Lyase C00000856 C00002674 C00016318 1 / 2
P43166 Carbonic anhydrase 7 Lyase C00000856 C00002674 C00016318 0 / 0
P18031 Tyrosine-protein phosphatase non-receptor type 1 Tyr C00016318 C00019065 0 / 0
P35218 Carbonic anhydrase 5A, mitochondrial Lyase C00000856 C00002674 0 / 0
P07451 Carbonic anhydrase 3 Lyase C00000856 C00002674 0 / 0
P15121 Aldose reductase Enzyme C00002674 C00019065 0 / 0
P23280 Carbonic anhydrase 6 Lyase C00000856 C00002674 0 / 0
Q9Y2D0 Carbonic anhydrase 5B, mitochondrial Lyase C00000856 C00002674 0 / 0
P22748 Carbonic anhydrase 4 Lyase C00000856 C00002674 1 / 1
P00533 Epidermal growth factor receptor TK tyrosine-protein kinase EGFR subfamily C00000856 1 / 8
P51649 Succinate-semialdehyde dehydrogenase, mitochondrial Oxidoreductase C00000856 1 / 1
Q8TDS4 Hydroxycarboxylic acid receptor 2 Hydroxycarboxylic acid receptor C00016318 0 / 0
O60656 UDP-glucuronosyltransferase 1-9 Enzyme C00000856 0 / 0
Q9HAW7 UDP-glucuronosyltransferase 1-7 Enzyme C00000856 0 / 0
Q9UQ49 Sialidase-3 Enzyme C00000856 0 / 0
O60218 Aldo-keto reductase family 1 member B10 Enzyme C00019065 0 / 0
P80404 4-aminobutyrate aminotransferase, mitochondrial Transferase C00000856 1 / 1
Q9HAW8 UDP-glucuronosyltransferase 1-10 Enzyme C00000856 0 / 0
Q9HAW9 UDP-glucuronosyltransferase 1-8 Enzyme C00000856 0 / 0
P51580 Thiopurine S-methyltransferase Enzyme C00000856 1 / 1
P19224 UDP-glucuronosyltransferase 1-6 Enzyme C00000856 0 / 0
P02768 Serum albumin Secreted protein C00016318 0 / 0
P17706 Tyrosine-protein phosphatase non-receptor type 2 Tyr C00019065 0 / 1
Q9BXC0 Hydroxycarboxylic acid receptor 1 Hydroxycarboxylic acid receptor C00016318 0 / 0

2 Gene in CTD interactions

gene gene name gene description KNApSAcK metabolite in interactions
3952 LEP, LEPD, OB, OBS leptin C00000856
6817 SULT1A1, HAST1/HAST2, P-PST, PST, ST1A1, ST1A3, STP, STP1, TSPST1 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1 (EC:2.8.2.1) C00000856

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (7)

OMIM preferred title UniProt
#613163 Gaba-transaminase deficiency P80404
#143860 Hyperchlorhidrosis, isolated O43570
#211980 Lung cancer P00533
#259730 Osteopetrosis, autosomal recessive 3; optb3 P00918
#600852 Retinitis pigmentosa 17; rp17 P22748
#271980 Succinic semialdehyde dehydrogenase deficiency; ssadhd P51649
#610460 Thiopurine s-methyltransferase deficiency P51580

KEGG DISEASE (17)

KEGG name UniProt
H01302 Hyperchlorhidrosis isolated (HCHLH) O43570 (related)
H00021 Renal cell carcinoma O43570 (marker)
Q16790 (marker)
H00016 Oral cancer P00533 (related)
P00533 (marker)
H00017 Esophageal cancer P00533 (related)
H00018 Gastric cancer P00533 (related)
H00022 Bladder cancer P00533 (related)
H00028 Choriocarcinoma P00533 (related)
H00030 Cervical cancer P00533 (related)
H00042 Glioma P00533 (related)
P00533 (marker)
H00055 Laryngeal cancer P00533 (related)
P00533 (marker)
H00241 Combined proximal and distal renal tubular acidosis (RTA type 3) P00918 (related)
H00436 Osteopetrosis P00918 (related)
H00408 Type I diabetes mellitus P17706 (related)
H00527 Retinitis pigmentosa (RP) P22748 (related)
H00964 Thiopurine S-methyltransferase deficiency (TPMT deficiency) P51580 (related)
H00835 Succinic semialdehyde dehydrogenase (SSADH) deficiency P51649 (related)
H01257 GABA-transaminase deficiency P80404 (related)

Diseases related to CTD interactions

1 disease in interactions with metabolites

MESH or OMIM name KNApSAcK
metabolite
D012220 Rhinitis C00000856