Citrus sudachi

• Index
• Plant Species
• Metabolite list (36)
• Human Protein
  / Gene in interactions
• Related Diseases

Species

KNApSAcK Entry

Organism name	Citrus sudachi
Genus	Citrus
Family	Rutaceae
Kingdom	Plantae

---

NCBI taxonomy

Entry

Linked NCBI taxonomy name	Citrus sudachi
Linked NCBI taxonomy ID	558546
Linked level	species

Family

Family in NCBI taxonomy	Rutaceae
ID	23513

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy	Viridiplantae
ID	33090

Plant class

Plant class	rosids
ID	71275

Metabolite list (36)

KNApSAcK ID	name	ChEMBL link	CTD link	# of proteins in ChEMBL interaction / related OMIM / related KEGG DISEASE	# of genes in CTD interaction / related diseases	KCF-S cluster	phytochemical cluster	figure
C00006287	3,8-Di-C-glucopyranosyldiosmetin					No. 1	No. 15
C00006233	3,8-Di-C-glucopyranosylapigenin					No. 1	No. 15
C00004445	5,7,4'-Trihydroxy-6,8,3'-trimethoxyflavone 7-(3-hydroxy-3-methylglutarate)-4'-glucoside					No. 2	No. 15
C00004442	5,7,4'-Trihydroxy-6,8,3'-trimethoxyflavone 4'-glucoside	CHEMBL477357				No. 2	No. 15
C00004447	5,7,4'-Trihydroxy-6,8,3'-trimethoxyflavone 4'-[6''-(3-hydroxy-3-methylglutaryl)glucoside]					No. 2	No. 15
C00004446	5,7,4'-Trihydroxy-6,8,3'-trimethoxyflavone 7-[6''-(3-hydroxy-3-methylglutaryl)glucoside]					No. 2	No. 15
C00001050	Dinatin / Hispidulin / 6-Methoxyapigenin / 6-O-Methylapigenin	CHEMBL293776	C055957	32 / 34 / 59	0 / 1	No. 3	No. 15
C00003890	Jaceosidin / 5,7,4'-Trihydroxy-6,3'-dimethoxyflavone	CHEMBL487601	C477508	1 / 0 / 0		No. 3	No. 15
C00003880	Pedunculin					No. 3	No. 15
C00003879	Xanthomicrol / 5-Hydroxy-2-(4-hydroxyphenyl)-6,7,8-trimethoxy-4H-1-benzopyran-4-one	CHEMBL476121	C462036			No. 3	No. 15
C00003876	Desmethoxysudachitin / 5,7,4'-Trihydroxy-6,8-dimethoxyflavone / 5,7-Dihydroxy-2-(4-hydroxyphenyl)-6,8-dimethoxy-4H-1-benzopyran-4-one	CHEMBL476120	C078367			No. 3	No. 15
C00003928	Sudachitin / Menthocubanone / Menthokubanone / 4',5,7-Trihydroxy-3',6,8-trimethoxyflavone / 5,7-Dihydroxy-2-(4-hydroxy-3-methoxyphenyl)-6,8-dimethoxy-4H-1-benzopyran-4-one	CHEMBL479233				No. 3	No. 15
C00014322	5,7,4'-Trihydroxyflavanone 7-(2,6-dirhamnosylglucoside) / Naringenin 7-O-(2'',6''-di-O-alpha-rhamnopyranosyl)-beta-glucopyranoside					No. 5	No. 15
C00003932	7-Methylsudachitin / 8-Methoxycirsilineol / 5,4'-Dihidroxy-6,7,8,3'-tetramethoxyflavone / 5-Hydroxy-2-(4-hydroxy-3-methoxyphenyl)-6,7,8-trimethoxy-4H-1-benzopyran-4-one	CHEMBL74272				No. 8	No. 15
C00000998	Prunin / Naringenin 7-O-beta-D-glucoside / 5,7,4'-Trihydroxyflavanone 7-O-beta-D-glucopyranoside	CHEMBL469654 CHEMBL526845		1 / 2 / 0		No. 12	No. 14
C00000970	Hesperidin	CHEMBL265606 CHEMBL449317 CHEMBL1314714 CHEMBL1328143 CHEMBL1535112 CHEMBL1574000 CHEMBL2140112	D006569	24 / 9 / 14	10 / 5	No. 48	No. 14
C00000983	Naringin	CHEMBL451532 CHEMBL451512 CHEMBL1742953 CHEMBL1970019	C005274	18 / 12 / 6	12 / 4	No. 48	No. 14
C00008295	Eriocitrin	CHEMBL2165586				No. 48	No. 14
C00000984	Narirutin	CHEMBL446246 CHEMBL507672 CHEMBL1441712				No. 48	No. 14
C00000987	Neohesperidin	CHEMBL506398 CHEMBL1885559		1 / 0 / 0		No. 48	No. 14
C00000995	Poncirin / Isosakuranetin-7-O-beta-D-neohesperidoside	CHEMBL451050				No. 48	No. 14
C00033259	Obacunoic acid	CHEMBL484838 CHEMBL1865426				No. 204	No. 51
C00041609	Isoobacunoic acid					No. 204	No. 51
C00003723	Obacunone	CHEMBL404140	C067207	1 / 0 / 0	8 / 0	No. 204	No. 51
C00041664	Methyl deacetylnomilinate					No. 204	No. 51
C00003719	Limonin	CHEMBL1523286 CHEMBL1886762 CHEMBL1897224 CHEMBL2004366	C001546	2 / 0 / 1	1 / 1	No. 204	No. 51
C00041703	Nomilinic acid					No. 204	No. 51
C00041445	Citrusin III					No. 290
C00033394	Sudachinoid B / (+)-Sudachinoid B					No. 823
C00033393	Sudachinoid A / (+)-Sudachinoid A					No. 823
C00033395	Sudachinoid C					No. 823
C00030753	Methyl ferulate / Ferulic acid methyl ester	CHEMBL32969				No. 876
C00002682	Vanillic acid / 3-Methoxy-4-hydroxybenzoic acid	CHEMBL120568	D014641	5 / 3 / 3	5 / 0	No. 1073
C00002743	Ferulic acid / 3-(4-Hydroxy-3-methoxyphenyl)-2-propenoic acid	CHEMBL32749	C004999	110 / 52 / 40	16 / 6	No. 1366	No. 6
C00041256	1S,2S,4R-Limonene-1,2-diol / (+)-1S,2S,4R-Limonene-1,2-diol					No. 2128
C00004448	Sudachiin D					No. 6489

Human Protein / Gene in interactions

171 ChEMBL Protein in interactions

accession	description	class description	KNApSAcK metabolite in interactions	# of diseases (OMIM / KEGG)
Q9UBT6	DNA polymerase kappa	Enzyme	C00000970 C00000987 C00001050	0 / 0
P08684	Cytochrome P450 3A4	Cytochrome P450 3A4	C00000970 C00002743 C00003719	0 / 1
P33765	Adenosine receptor A3	Adenosine receptor	C00001050 C00002743	0 / 0
O00255	Menin	Unclassified protein	C00000970 C00001050	2 / 5
Q9NUW8	Tyrosyl-DNA phosphodiesterase 1	Enzyme	C00000970 C00001050	1 / 1
P10635	Cytochrome P450 2D6	Cytochrome P450 2D6	C00000970 C00002743	1 / 0
Q9Y251	Heparanase	Enzyme	C00000970 C00000983	0 / 0
P22309	UDP-glucuronosyltransferase 1-1	Enzyme	C00000983 C00002743	5 / 1
P27695	DNA-(apurinic or apyrimidinic site) lyase	Enzyme	C00000970 C00001050	0 / 0
Q9UNA4	DNA polymerase iota	Enzyme	C00000970 C00002682	0 / 0
P22310	UDP-glucuronosyltransferase 1-4	Enzyme	C00000983 C00002743	3 / 0
Q03164	Histone-lysine N-methyltransferase 2A	Enzyme	C00000970 C00001050	1 / 2
P33261	Cytochrome P450 2C19	Cytochrome P450 2C19	C00000970 C00002743	1 / 1
P03372	Estrogen receptor	NR3A1	C00002682 C00002743	1 / 1
P06746	DNA polymerase beta	Enzyme	C00000970 C00001050	0 / 0
Q96QE3	ATPase family AAA domain-containing protein 5	Unclassified protein	C00001050 C00003723	0 / 0
P05177	Cytochrome P450 1A2	Cytochrome P450 1A2	C00000970 C00002743	0 / 0
P83916	Chromobox protein homolog 1	Unclassified protein	C00000970 C00000983	0 / 0
P11308	Transcriptional regulator ERG	Unclassified protein	C00000970 C00000983	1 / 2
P54855	UDP-glucuronosyltransferase 2B15	Enzyme	C00000983 C00002743	0 / 0
O75496	Geminin	Unclassified protein	C00000983 C00002743	0 / 0
P11712	Cytochrome P450 2C9	Cytochrome P450 2C9	C00000970 C00002743	0 / 1
P61088	Ubiquitin-conjugating enzyme E2 N	Enzyme	C00000983	0 / 0
P14780	Matrix metalloproteinase-9	M10A	C00002743	2 / 2
Q13526	Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1	Enzyme	C00000970	0 / 0
Q13315	Serine-protein kinase ATM	Atypical serine/threonine protein kinase PIKK subfamily	C00001050	1 / 4
P62158	Calmodulin	Unclassified protein	C00000970	1 / 0
P55789	FAD-linked sulfhydryl oxidase ALR	Enzyme	C00001050	1 / 0
P47989	Xanthine dehydrogenase/oxidase	Oxidoreductase	C00002743	1 / 1
P00918	Carbonic anhydrase 2	Lyase	C00002743	1 / 2
P07550	Beta-2 adrenergic receptor	Adrenergic receptor	C00002743	0 / 1
P21397	Amine oxidase [flavin-containing] A	Oxidoreductase	C00002743	1 / 1
P25021	Histamine H2 receptor	Histamine receptor	C00002743	0 / 0
P35367	Histamine H1 receptor	Histamine receptor	C00002743	0 / 0
Q01959	Sodium-dependent dopamine transporter	Dopamine	C00002743	1 / 0
P08912	Muscarinic acetylcholine receptor M5	Acetylcholine receptor	C00002743	0 / 0
P18825	Alpha-2C adrenergic receptor	Adrenergic receptor	C00002743	0 / 0
P13945	Beta-3 adrenergic receptor	Adrenergic receptor	C00002743	0 / 0
P34969	5-hydroxytryptamine receptor 7	Serotonin receptor	C00002743	0 / 0
P08183	Multidrug resistance protein 1	drug	C00000983	1 / 0
P25024	C-X-C chemokine receptor type 1	CXC chemokine receptor	C00002743	0 / 0
P06241	Tyrosine-protein kinase Fyn	Src	C00002743	0 / 0
Q08209	Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform	Ser_Thr	C00002743	0 / 0
P17252	Protein kinase C alpha type	Alpha	C00002743	0 / 0
Q9GZU7	Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1	Enzyme	C00000970	0 / 0
P00533	Epidermal growth factor receptor	TK tyrosine-protein kinase EGFR subfamily	C00002743	1 / 8
P14416	D(2) dopamine receptor	Dopamine receptor	C00002743	2 / 0
P23219	Prostaglandin G/H synthase 1	Oxidoreductase	C00002743	0 / 0
P37288	Vasopressin V1a receptor	Vasopressin and oxytocin receptor	C00002743	0 / 0
P41145	Kappa-type opioid receptor	Opioid receptor	C00002743	0 / 0
Q9Y271	Cysteinyl leukotriene receptor 1	Leukotriene receptor	C00002743	0 / 0
P29274	Adenosine receptor A2a	Adenosine receptor	C00002743	0 / 0
P23280	Carbonic anhydrase 6	Lyase	C00002743	0 / 0
P25929	Neuropeptide Y receptor type 1	Neuropeptide Y receptor	C00002743	0 / 0
P50052	Type-2 angiotensin II receptor	Angiotensin receptor	C00002743	1 / 1
P17948	Vascular endothelial growth factor receptor 1	Vegfr	C00002743	0 / 0
P41968	Melanocortin receptor 3	Melanocortin receptor	C00002743	1 / 0
Q9ULX7	Carbonic anhydrase 14	Lyase	C00002743	0 / 0
O43570	Carbonic anhydrase 12	Lyase	C00002743	1 / 2
P11509	Cytochrome P450 2A6	Cytochrome P450 2A6	C00002743	0 / 0
Q8TDS4	Hydroxycarboxylic acid receptor 2	Hydroxycarboxylic acid receptor	C00002743	0 / 0
P42858	Huntingtin	Unclassified protein	C00002682	1 / 1
P29466	Caspase-1	C14	C00002743	0 / 0
P51151	Ras-related protein Rab-9A	Unclassified protein	C00001050	0 / 0
P46721	Solute carrier organic anion transporter family member 1A2	Unclassified protein	C00000983	0 / 0
P43166	Carbonic anhydrase 7	Lyase	C00002743	0 / 0
P04035	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Oxidoreductase	C00002743	0 / 0
P08913	Alpha-2A adrenergic receptor	Adrenergic receptor	C00002743	0 / 0
P21917	D(4) dopamine receptor	Dopamine receptor	C00002743	0 / 0
P30988	Calcitonin receptor	Calcitonin receptor	C00002743	0 / 0
P35462	D(3) dopamine receptor	Dopamine receptor	C00002743	1 / 0
P41143	Delta-type opioid receptor	Opioid receptor	C00002743	0 / 0
Q92731	Estrogen receptor beta	NR3A2	C00002743	0 / 1
P41595	5-hydroxytryptamine receptor 2B	Serotonin receptor	C00002743	0 / 0
P15121	Aldose reductase	Enzyme	C00002682	0 / 0
P25101	Endothelin-1 receptor	Endothelin receptor	C00002743	0 / 0
P30411	B2 bradykinin receptor	Bradykinin receptor	C00002743	0 / 0
P32245	Melanocortin receptor 4	Melanocortin receptor	C00002743	1 / 0
P00915	Carbonic anhydrase 1	Lyase	C00002743	0 / 0
P32238	Cholecystokinin receptor type A	Cholecystokinin receptor	C00002743	0 / 0
P08311	Cathepsin G	S1A	C00002743	0 / 0
Q99720	Sigma non-opioid intracellular receptor 1	Membrane receptor	C00002743	1 / 0
P03956	Interstitial collagenase	M10A	C00002743	0 / 1
P32241	Vasoactive intestinal polypeptide receptor 1	Vasoactive intestinal peptide receptor	C00002743	0 / 0
Q9Y253	DNA polymerase eta	Enzyme	C00000970	1 / 1
P35218	Carbonic anhydrase 5A, mitochondrial	Lyase	C00002743	0 / 0
Q9Y2D0	Carbonic anhydrase 5B, mitochondrial	Lyase	C00002743	0 / 0
Q9NPD5	Solute carrier organic anion transporter family member 1B3	Electrochemical transporter	C00000983	1 / 0
P51843	Nuclear receptor subfamily 0 group B member 1	Nuclear hormone receptor subfamily 0 group B member 1	C00001050	2 / 2
P04150	Glucocorticoid receptor	NR3C1	C00002743	0 / 1
P08172	Muscarinic acetylcholine receptor M2	Acetylcholine receptor	C00002743	2 / 0
P11229	Muscarinic acetylcholine receptor M1	Acetylcholine receptor	C00002743	0 / 0
P11511	Cytochrome P450 19A1	Cytochrome P450 19A1	C00000983	2 / 2
P14679	Tyrosinase	Oxidoreductase	C00002743	4 / 2
P21554	Cannabinoid receptor 1	Cannabinoid receptor	C00002743	0 / 0
P31645	Sodium-dependent serotonin transporter	Serotonin	C00002743	2 / 0
P04626	Receptor tyrosine-protein kinase erbB-2	TK tyrosine-protein kinase EGFR subfamily	C00002743	5 / 9
P20309	Muscarinic acetylcholine receptor M3	Acetylcholine receptor	C00002743	1 / 0
P21452	Substance-K receptor	Neurokinin receptor	C00002743	0 / 0
P51679	C-C chemokine receptor type 4	CC chemokine receptor	C00002743	0 / 0
P51681	C-C chemokine receptor type 5	CC chemokine receptor	C00002743	3 / 0
P50406	5-hydroxytryptamine receptor 6	Serotonin receptor	C00002743	0 / 0
P41597	C-C chemokine receptor type 2	CC chemokine receptor	C00002743	1 / 0
P28482	Mitogen-activated protein kinase 1	Erk	C00002743	0 / 0
P08575	Receptor-type tyrosine-protein phosphatase C	Enzyme	C00002743	2 / 1
P04062	Glucosylceramidase	Enzyme	C00001050	6 / 4
Q16790	Carbonic anhydrase 9	Lyase	C00002743	0 / 1
Q9UNQ0	ATP-binding cassette sub-family G member 2	ATP binding cassette	C00000998	2 / 0
O15118	Niemann-Pick C1 protein	Unclassified protein	C00001050	1 / 1
P49146	Neuropeptide Y receptor type 2	Neuropeptide Y receptor	C00002743	0 / 0
O76074	cGMP-specific 3',5'-cyclic phosphodiesterase	PDE_5A	C00002743	0 / 0
Q16539	Mitogen-activated protein kinase 14	p38	C00002743	0 / 0
P08588	Beta-1 adrenergic receptor	Adrenergic receptor	C00002743	1 / 0
P22303	Acetylcholinesterase	Hydrolase	C00002743	1 / 0
P28223	5-hydroxytryptamine receptor 2A	Serotonin receptor	C00002743	0 / 0
P28335	5-hydroxytryptamine receptor 2C	Serotonin receptor	C00002743	0 / 0
P35372	Mu-type opioid receptor	Opioid receptor	C00002743	0 / 0
P08173	Muscarinic acetylcholine receptor M4	Acetylcholine receptor	C00002743	0 / 0
P25103	Substance-P receptor	Neurokinin receptor	C00002743	0 / 0
P25105	Platelet-activating factor receptor	PAF receptor	C00002743	0 / 0
P33032	Melanocortin receptor 5	Melanocortin receptor	C00002743	0 / 0
P51580	Thiopurine S-methyltransferase	Enzyme	C00002682	1 / 1
Q13093	Platelet-activating factor acetylhydrolase	Enzyme	C00002743	3 / 0
P08246	Neutrophil elastase	S1A	C00002743	2 / 1
P05181	Cytochrome P450 2E1	Cytochrome P450 2E1	C00002743	0 / 0
Q12809	Potassium voltage-gated channel subfamily H member 2	KCNH, Kv10-12.x (Ether-a-go-go)	C00002743	2 / 2
O75164	Lysine-specific demethylase 4A	Enzyme	C00000970	0 / 0
P27361	Mitogen-activated protein kinase 3	Erk	C00002743	0 / 0
P35354	Prostaglandin G/H synthase 2	Oxidoreductase	C00002743	0 / 3
P21728	D(1A) dopamine receptor	Dopamine receptor	C00002743	0 / 0
P10636	Microtubule-associated protein tau	Unclassified protein	C00001050	4 / 3
P23975	Sodium-dependent noradrenaline transporter	Norepinephrine	C00002743	1 / 1
P25100	Alpha-1D adrenergic receptor	Adrenergic receptor	C00002743	0 / 0
P30542	Adenosine receptor A1	Adenosine receptor	C00002743	0 / 0
P18089	Alpha-2B adrenergic receptor	Adrenergic receptor	C00002743	0 / 0
P24557	Thromboxane-A synthase	Cytochrome P450 5A1	C00002743	1 / 1
P07451	Carbonic anhydrase 3	Lyase	C00002743	0 / 0
P06239	Tyrosine-protein kinase Lck	Src	C00002743	0 / 1
P25025	C-X-C chemokine receptor type 2	CXC chemokine receptor	C00002743	0 / 0
O94956	Solute carrier organic anion transporter family member 2B1	Unclassified protein	C00000983	0 / 0
P22748	Carbonic anhydrase 4	Lyase	C00002743	1 / 1
Q12794	Hyaluronidase-1	Enzyme	C00002743	1 / 2
Q9UIF8	Bromodomain adjacent to zinc finger domain protein 2B	Unclassified protein	C00000970	0 / 0
B2RXH2	Lysine-specific demethylase 4E	Enzyme	C00002743	0 / 0
P46063	ATP-dependent DNA helicase Q1	Enzyme	C00003719	0 / 0
Q96KQ7	Histone-lysine N-methyltransferase EHMT2	Enzyme	C00000983	0 / 0
Q9Y6L6	Solute carrier organic anion transporter family member 1B1	Electrochemical transporter	C00000983	1 / 0
O75874	Isocitrate dehydrogenase [NADP] cytoplasmic	Enzyme	C00000983	1 / 0
P59538	Taste receptor type 2 member 31	Taste receptor (taste family GPCR)	C00003890	0 / 0
P04637	Cellular tumor antigen p53	Transcription Factor	C00001050	7 / 37
P18031	Tyrosine-protein phosphatase non-receptor type 1	Tyr	C00000983	0 / 0
Q9UN88	Gamma-aminobutyric acid receptor subunit theta	GABA-A theta	C00001050	0 / 0
P28472	Gamma-aminobutyric acid receptor subunit beta-3	GABA-A beta	C00001050	1 / 0
P14867	Gamma-aminobutyric acid receptor subunit alpha-1	GABA-A alpha	C00001050	1 / 1
P48169	Gamma-aminobutyric acid receptor subunit alpha-4	GABA-A alpha	C00001050	0 / 0
O14764	Gamma-aminobutyric acid receptor subunit delta	GABA-A delta	C00001050	1 / 1
P31644	Gamma-aminobutyric acid receptor subunit alpha-5	GABA-A alpha	C00001050	0 / 0
Q99928	Gamma-aminobutyric acid receptor subunit gamma-3	GABA-A gamma	C00001050	0 / 0
P78334	Gamma-aminobutyric acid receptor subunit epsilon	GABA-A epsilon	C00001050	0 / 0
Q8N1C3	Gamma-aminobutyric acid receptor subunit gamma-1	GABA-A gamma	C00001050	0 / 0
P34903	Gamma-aminobutyric acid receptor subunit alpha-3	GABA-A alpha	C00001050	0 / 0
O00591	Gamma-aminobutyric acid receptor subunit pi	GABA-A pi	C00001050	0 / 0
P47870	Gamma-aminobutyric acid receptor subunit beta-2	GABA-A beta	C00001050	0 / 0
P18507	Gamma-aminobutyric acid receptor subunit gamma-2	GABA-A gamma	C00001050	4 / 2
P18505	Gamma-aminobutyric acid receptor subunit beta-1	GABA-A beta	C00001050	0 / 0
Q16445	Gamma-aminobutyric acid receptor subunit alpha-6	GABA-A alpha	C00001050	0 / 0
P47869	Gamma-aminobutyric acid receptor subunit alpha-2	GABA-A alpha	C00001050	1 / 0
Q02410	Amyloid beta A4 precursor protein-binding family A member 1	Unclassified protein	C00000970	0 / 0
Q00975	Voltage-dependent N-type calcium channel subunit alpha-1B	N-TYPE	C00000970	0 / 0
O94925	Glutaminase kidney isoform, mitochondrial	Enzyme	C00000970	0 / 0
Q13148	TAR DNA-binding protein 43	Unclassified protein	C00000983	1 / 1

38 Gene in CTD interactions

gene	gene name	gene description	KNApSAcK metabolite in interactions
5743	PTGS2, COX-2, COX2, GRIPGHS, PGG/HS, PGHS-2, PHS-2, hCox-2	prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) (EC:1.14.99.1)	C00000970 C00002743 C00003723
836	CASP3, CPP32, CPP32B, SCA-1	caspase 3, apoptosis-related cysteine peptidase (EC:3.4.22.56)	C00000983 C00003723
3383	ICAM1, BB2, CD54, P3.58	intercellular adhesion molecule 1	C00000970 C00000983
54575	UGT1A10, UDPGT, UGT-1J, UGT1-10, UGT1.10, UGT1J	UDP glucuronosyltransferase 1 family, polypeptide A10 (EC:2.4.1.17)	C00002682 C00002743
1543	CYP1A1, AHH, AHRR, CP11, CYP1, P1-450, P450-C, P450DX	cytochrome P450, family 1, subfamily A, polypeptide 1 (EC:1.14.14.1)	C00000983 C00002743
1544	CYP1A2, CP12, P3-450, P450(PA)	cytochrome P450, family 1, subfamily A, polypeptide 2 (EC:1.14.14.1)	C00000983 C00002743
7157	TP53, BCC7, LFS1, P53, TRP53	tumor protein p53	C00000983 C00003723
581	BAX, BCL2L4	BCL2-associated X protein	C00000983 C00003723
54576	UGT1A8, UDPGT, UDPGT_1-8, UGT-1H, UGT1-08, UGT1.8, UGT1A8S, UGT1H	UDP glucuronosyltransferase 1 family, polypeptide A8 (EC:2.4.1.17)	C00002682 C00002743
1576	CYP3A4, CP33, CP34, CYP3A, CYP3A3, CYPIIIA3, CYPIIIA4, HLP, NF-25, P450C3, P450PCN1	cytochrome P450, family 3, subfamily A, polypeptide 4 (EC:1.14.13.67 1.14.13.97 1.14.13.32 1.14.13.157)	C00000983 C00003719
54577	UGT1A7, UDPGT, UDPGT_1-7, UGT-1G, UGT1-07, UGT1.7, UGT1G	UDP glucuronosyltransferase 1 family, polypeptide A7 (EC:2.4.1.17)	C00002682 C00002743
54659	UGT1A3, UDPGT, UDPGT_1-3, UGT-1C, UGT1-03, UGT1.3, UGT1C	UDP glucuronosyltransferase 1 family, polypeptide A3 (EC:2.4.1.17)	C00002682 C00002743
842	CASP9, APAF-3, APAF3, ICE-LAP6, MCH6, PPP1R56	caspase 9, apoptosis-related cysteine peptidase (EC:3.4.22.62)	C00000983 C00003723
7299	TYR, ATN, CMM8, OCA1, OCA1A, OCAIA, SHEP3	tyrosinase (EC:1.14.18.1)	C00002743
6319	SCD, FADS5, MSTP008, SCD1, SCDOS	stearoyl-CoA desaturase (delta-9-desaturase) (EC:1.14.19.1)	C00002743
5925	RB1, OSRC, RB, p105-Rb, pRb, pp110	retinoblastoma 1	C00002743
5742	PTGS1, COX1, COX3, PCOX1, PES-1, PGG/HS, PGHS-1, PGHS1, PHS1, PTGHS	prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase) (EC:1.14.99.1)	C00002743
5595	MAPK3, ERK-1, ERK1, ERT2, HS44KDAP, HUMKER1A, P44ERK1, P44MAPK, PRKM3, p44-ERK1, p44-MAPK	mitogen-activated protein kinase 3 (EC:2.7.11.24)	C00002743
5594	MAPK1, ERK, ERK2, ERT1, MAPK2, P42MAPK, PRKM1, PRKM2, p38, p40, p41, p41mapk	mitogen-activated protein kinase 1 (EC:2.7.11.24)	C00002743
1026	CDKN1A, CAP20, CDKN1, CIP1, MDA-6, P21, SDI1, WAF1, p21CIP1	cyclin-dependent kinase inhibitor 1A (p21, Cip1)	C00002743
1545	CYP1B1, CP1B, CYPIB1, GLC3A, P4501B1	cytochrome P450, family 1, subfamily B, polypeptide 1 (EC:1.14.14.1)	C00000983
1559	CYP2C9, CPC9, CYP2C, CYP2C10, CYPIIC9, P450IIC9	cytochrome P450, family 2, subfamily C, polypeptide 9 (EC:1.14.13.48 1.14.13.49 1.14.13.80)	C00000983
8772	FADD, MORT1	Fas (TNFRSF6)-associated via death domain	C00000983
355	FAS, ALPS1A, APO-1, APT1, CD95, FAS1, FASTM, TNFRSF6	Fas cell surface death receptor	C00000983
595	CCND1, BCL1, D11S287E, PRAD1, U21B31	cyclin D1	C00002743
23621	BACE1, ASP2, BACE, HSPC104	beta-site APP-cleaving enzyme 1 (EC:3.4.23.46)	C00002743
596	BCL2, Bcl-2, PPP1R50	B-cell CLL/lymphoma 2	C00003723
841	CASP8, ALPS2B, CAP4, Casp-8, FLICE, MACH, MCH5	caspase 8, apoptosis-related cysteine peptidase (EC:3.4.22.61)	C00003723
5970	RELA, NFKB3, p65	v-rel avian reticuloendotheliosis viral oncogene homolog A	C00003723
3553	IL1B, IL-1, IL1-BETA, IL1F2	interleukin 1, beta	C00000970
3569	IL6, BSF2, HGF, HSF, IFNB2, IL-6	interleukin 6 (interferon, beta 2)	C00000970
3576	IL8, CXCL8, GCP-1, GCP1, LECT, LUCT, LYNAP, MDNCF, MONAP, NAF, NAP-1, NAP1	interleukin 8	C00000970
5599	MAPK8, JNK, JNK-46, JNK1, JNK1A2, JNK21B1/2, PRKM8, SAPK1, SAPK1c	mitogen-activated protein kinase 8 (EC:2.7.11.24)	C00000970
5601	MAPK9, JNK-55, JNK2, JNK2A, JNK2ALPHA, JNK2B, JNK2BETA, PRKM9, SAPK, SAPK1a, p54a, p54aSAPK	mitogen-activated protein kinase 9 (EC:2.7.11.24)	C00000970
4318	MMP9, CLG4B, GELB, MANDP2, MMP-9	matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase) (EC:3.4.24.35)	C00000970
7124	TNF, DIF, TNF-alpha, TNFA, TNFSF2	tumor necrosis factor	C00000970
7412	VCAM1, CD106, INCAM-100	vascular cell adhesion molecule 1	C00000970
4846	NOS3, ECNOS, eNOS	nitric oxide synthase 3 (endothelial cell) (EC:1.14.13.39)	C00002682

Related Diseases

Diseases related to proteins in ChEMBL interactions

Diseases related to CTD interactions