Citrullus colocynthis (L.)

• Index
• Plant Species
• Metabolite list (14)
• Human Protein
  / Gene in interactions
• Related Diseases

Species

KNApSAcK Entry

Organism name	Citrullus colocynthis (L.)
Genus	Citrullus
Family	Cucurbitaceae
Kingdom	Plantae

---

NCBI taxonomy

Entry

Linked NCBI taxonomy name	Citrullus
Linked NCBI taxonomy ID	3653
Linked level	genus

Family

Family in NCBI taxonomy	Cucurbitaceae
ID	3650

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy	Viridiplantae
ID	33090

Plant class

Plant class	rosids
ID	71275

Metabolite list (14)

KNApSAcK ID	name	ChEMBL link	CTD link	# of proteins in ChEMBL interaction / related OMIM / related KEGG DISEASE	# of genes in CTD interaction / related diseases	KCF-S cluster	phytochemical cluster	figure
C00001059	Isovitexin / Saponaretin / Homovitexin / 6-C-beta-D-Glucopyranosylapigenin / 6-beta-D-Glucopyranosyl-4',5,7-trihydroxyflavone / 6-beta-D-Glucopyranosyl-5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one	CHEMBL465360 CHEMBL1601394	C049772	28 / 20 / 19		No. 22	No. 15
C00030466	Helicid / 4-(beta-D-glucopyranosyloxy) benzaldehyde	CHEMBL201358 CHEMBL461515	C055677	2 / 2 / 2		No. 45	No. 72
C00029534	4-Hydroxybenzyl beta-D-glucopyranoside					No. 45	No. 72
C00029516	Gastrodin / (-)-Gastrodin / 4-(beta-D-Glucopyranosyloxy) benzyl alcohol	CHEMBL274739	C045345	2 / 2 / 2	0 / 2	No. 45	No. 72
C00029812	Benzyl beta-D-glucopyranoside / (-)-Benzyl-O-beta-D-glucopyranoside	CHEMBL1170453 CHEMBL2336738	C410942			No. 45	No. 72
C00030034	Cucurbitacin l 2-O-beta-D-glucopyranoside	CHEMBL449483		1 / 4 / 2		No. 315
C00030001	Colocynthoside A / (-)-Colocynthoside A					No. 315
C00030032	Cucurbitacin K 2-O-beta-glucopyranoside / Cucurbitacin K 2-O-beta-D-glucopyranoside	CHEMBL1923785 CHEMBL1923786				No. 315
C00030029	Elaterinide / Gratiotoxin / Cucurbitacin E-2-O-glucoside / alpha-Elaterin 2-D-glucopyranoside / Cucurbitacin E 2-O-beta-D-glucopyranoside	CHEMBL1455367 CHEMBL1765381		8 / 5 / 3		No. 315
C00030031	Cucurbitacin I 2-O-beta-D-glucopyranoside	CHEMBL1723294 CHEMBL1765380		2 / 0 / 0		No. 315
C00030608	Khekadaengoside E / (-)-Khekadaengoside E					No. 315
C00030002	Colocynthoside B / (-)-Colocynthoside B					No. 675	No. 51
C00029478	3,4'-Dihydroxypropiophenone / 4-Hydroxy-(3-hydroxypropionyl)benzene	CHEMBL1417159		25 / 10 / 7		No. 2849
C00029477	beta-Hydroxypropiovanillone / omega-Hydroxypropioguaiacone / 3,4'-Dihydroxy-3'-methoxypropiophenone / 3-Hydroxy-1-(4-hydroxy-3-methoxyphenyl)-1-propanone	CHEMBL485875				No. 2959

Human Protein / Gene in interactions

42 ChEMBL Protein in interactions

accession	description	class description	KNApSAcK metabolite in interactions	# of diseases (OMIM / KEGG)
Q96QE3	ATPase family AAA domain-containing protein 5	Unclassified protein	C00001059 C00030029 C00030031	0 / 0
Q9UNA4	DNA polymerase iota	Enzyme	C00001059 C00029478 C00030029	0 / 0
Q9Y468	Lethal(3)malignant brain tumor-like protein 1	Unclassified protein	C00001059 C00029478 C00030029	0 / 0
P39748	Flap endonuclease 1	Enzyme	C00001059 C00029478	0 / 0
P10253	Lysosomal alpha-glucosidase	Hydrolase	C00001059 C00029478	1 / 1
Q13526	Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1	Enzyme	C00001059 C00029478	0 / 0
P51649	Succinate-semialdehyde dehydrogenase, mitochondrial	Oxidoreductase	C00029516 C00030466	1 / 1
O94925	Glutaminase kidney isoform, mitochondrial	Enzyme	C00001059 C00029478	0 / 0
Q9NR56	Muscleblind-like protein 1	Unclassified protein	C00001059 C00029478	1 / 0
P00352	Retinal dehydrogenase 1	Enzyme	C00001059 C00029478	0 / 0
O75874	Isocitrate dehydrogenase [NADP] cytoplasmic	Enzyme	C00001059 C00030029	1 / 0
P06746	DNA polymerase beta	Enzyme	C00001059 C00029478	0 / 0
Q9NUW8	Tyrosyl-DNA phosphodiesterase 1	Enzyme	C00001059 C00029478	1 / 1
P46063	ATP-dependent DNA helicase Q1	Enzyme	C00001059 C00029478	0 / 0
B2RXH2	Lysine-specific demethylase 4E	Enzyme	C00001059 C00029478	0 / 0
Q9Y253	DNA polymerase eta	Enzyme	C00001059 C00029478	1 / 1
Q9UBT6	DNA polymerase kappa	Enzyme	C00001059 C00029478	0 / 0
P27695	DNA-(apurinic or apyrimidinic site) lyase	Enzyme	C00001059 C00029478	0 / 0
Q14191	Werner syndrome ATP-dependent helicase	Enzyme	C00001059 C00029478	2 / 1
P83916	Chromobox protein homolog 1	Unclassified protein	C00029478 C00030031	0 / 0
O75164	Lysine-specific demethylase 4A	Enzyme	C00001059 C00029478	0 / 0
Q9UIF8	Bromodomain adjacent to zinc finger domain protein 2B	Unclassified protein	C00001059 C00029478	0 / 0
P80404	4-aminobutyrate aminotransferase, mitochondrial	Transferase	C00029516 C00030466	1 / 1
Q07820	Induced myeloid leukemia cell differentiation protein Mcl-1	Other cytosolic protein	C00029478	0 / 0
P30989	Neurotensin receptor type 1	Neurotensin receptor	C00001059	0 / 0
P10696	Alkaline phosphatase, placental-like	Enzyme	C00029478	0 / 1
P14679	Tyrosinase	Oxidoreductase	C00030034	4 / 2
P05186	Alkaline phosphatase, tissue-nonspecific isozyme	Enzyme	C00029478	3 / 1
Q16236	Nuclear factor erythroid 2-related factor 2	Unclassified protein	C00001059	0 / 0
P09923	Intestinal-type alkaline phosphatase	Enzyme	C00029478	0 / 0
P63092	Guanine nucleotide-binding protein G(s) subunit alpha isoforms short	Other membrane protein	C00001059	7 / 3
O75496	Geminin	Unclassified protein	C00030029	0 / 0
Q96KQ7	Histone-lysine N-methyltransferase EHMT2	Enzyme	C00029478	0 / 0
P84022	Mothers against decapentaplegic homolog 3	Unclassified protein	C00030029	2 / 0
P17405	Sphingomyelin phosphodiesterase	Enzyme	C00001059	2 / 2
O00255	Menin	Unclassified protein	C00001059	2 / 5
Q03164	Histone-lysine N-methyltransferase 2A	Enzyme	C00001059	1 / 2
Q13951	Core-binding factor subunit beta	Unclassified protein	C00001059	0 / 1
Q01196	Runt-related transcription factor 1	Unclassified protein	C00001059	1 / 4
P54132	Bloom syndrome protein	Enzyme	C00029478	1 / 2
Q99700	Ataxin-2	Unclassified protein	C00030029	1 / 1
Q06710	Paired box protein Pax-8	Unclassified protein	C00030029	1 / 2

Related Diseases

Diseases related to proteins in ChEMBL interactions

Diseases related to CTD interactions