| Organism name | Fraxinus ornus |
|---|---|
| Genus | Fraxinus |
| Family | Oleaceae |
| Kingdom | Plantae |
| Linked NCBI taxonomy name | Fraxinus ornus |
|---|---|
| Linked NCBI taxonomy ID | 38874 |
| Linked level | species |
| Family in NCBI taxonomy | Oleaceae |
|---|---|
| ID | 4144 |
| Kingdom (Superkingdom) in NCBI taxonomy | Viridiplantae |
|---|---|
| ID | 33090 |
| Plant class | asterids |
|---|---|
| ID | 71274 |
| KNApSAcK ID | name | ChEMBL link | CTD link |
# of proteins in
ChEMBL interaction / related OMIM / related KEGG DISEASE |
# of genes in
CTD interaction / related diseases |
KCF-S
cluster |
phytochemical
cluster |
figure |
|---|---|---|---|---|---|---|---|---|
|
C00037437
|
Lugrandoside
/ (-)-Lugrandoside |
No. 33 |
|
|||||
|
C00030516
|
Isoacteoside
/ Isoverbascoside |
CHEMBL504873
|
C064683
|
6 / 5 / 4 | No. 33 |
|
||
|
C00003093
|
Oleuropein
|
CHEMBL1911053
|
C002769
|
8 / 5 | No. 243 |
|
||
|
C00037421
|
Ligstroside
/ (-)-Ligstroside |
CHEMBL1086877
|
1 / 1 / 0 | No. 243 |
|
|||
|
C00033686
|
Calceolarioside B
|
CHEMBL518414
|
3 / 2 / 5 | No. 382 |
|
|||
|
C00040787
|
2-(4-Hydroxyphenyl)-ethyl-(6-O-caffeoyl)-beta-D-glucopyranoside
|
No. 382 |
|
|||||
|
C00007191
|
(+)-8(1)-Hydroxypinoresinol
|
CHEMBL471274
|
No. 700 | No. 21 |
|
|||
|
C00042518
|
Framoside
|
No. 842 |
|
|||||
|
C00042597
|
Hydroxyframoside B
|
No. 842 |
|
|||||
|
C00042596
|
Hydroxyframoside A
|
No. 842 |
|
|||||
|
C00001150
|
Stachyose
|
CHEMBL1625803
|
C005695
|
No. 1212 |
|
|||
|
C00042598
|
Hydroxyornoside
/ (-)-Hydroxyornoside |
No. 4674 |
|
| accession | description | class description | KNApSAcK metabolite in interactions |
# of diseases
(OMIM / KEGG) |
|---|---|---|---|---|
| P35354 | Prostaglandin G/H synthase 2 | Oxidoreductase | C00033686 | 0 / 3 |
| P17252 | Protein kinase C alpha type | Alpha | C00033686 | 0 / 0 |
| P39900 | Macrophage metalloelastase | M10A | C00030516 | 0 / 0 |
| P14780 | Matrix metalloproteinase-9 | M10A | C00030516 | 2 / 2 |
| P03956 | Interstitial collagenase | M10A | C00030516 | 0 / 1 |
| P11511 | Cytochrome P450 19A1 | Cytochrome P450 19A1 | C00033686 | 2 / 2 |
| P45452 | Collagenase 3 | M10A | C00030516 | 1 / 1 |
| P08253 | 72 kDa type IV collagenase | M10A | C00030516 | 1 / 3 |
| P14672 | Solute carrier family 2, facilitated glucose transporter member 4 | Unclassified protein | C00037421 | 1 / 0 |
| P08254 | Stromelysin-1 | M10A | C00030516 | 1 / 0 |
| gene | gene name | gene description | KNApSAcK metabolite in interactions |
|---|---|---|---|
| 1588 | CYP19A1, ARO, ARO1, CPV1, CYAR, CYP19, CYPXIX, P-450AROM | cytochrome P450, family 19, subfamily A, polypeptide 1 (EC:1.14.14.1) |
C00003093
|
| 3383 | ICAM1, BB2, CD54, P3.58 | intercellular adhesion molecule 1 |
C00003093
|
| 4318 | MMP9, CLG4B, GELB, MANDP2, MMP-9 | matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase) (EC:3.4.24.35) |
C00003093
|
| 5743 | PTGS2, COX-2, COX2, GRIPGHS, PGG/HS, PGHS-2, PHS-2, hCox-2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) (EC:1.14.99.1) |
C00003093
|
| 5970 | RELA, NFKB3, p65 | v-rel avian reticuloendotheliosis viral oncogene homolog A |
C00003093
|
| 6401 | SELE, CD62E, ELAM, ELAM1, ESEL, LECAM2 | selectin E |
C00003093
|
| 7124 | TNF, DIF, TNF-alpha, TNFA, TNFSF2 | tumor necrosis factor |
C00003093
|
| 7412 | VCAM1, CD106, INCAM-100 | vascular cell adhesion molecule 1 |
C00003093
|
| OMIM | preferred title | UniProt |
|---|---|---|
| #613546 | Aromatase deficiency |
P11511
|
| #139300 | Aromatase excess syndrome; aexs |
P11511
|
| #614466 | Coronary heart disease, susceptibility to, 6; chds6 |
P08254
|
| #125853 | Diabetes mellitus, noninsulin-dependent; niddm |
P14672
|
| #603932 | Intervertebral disc disease; idd |
P14780
|
| #613073 | Metaphyseal anadysplasia 2; mandp2 |
P14780
|
| #259600 | Multicentric osteolysis, nodulosis, and arthropathy; mona |
P08253
|
| #602111 | Spondyloepimetaphyseal dysplasia, missouri type |
P45452
|
| KEGG | name | UniProt |
|---|---|---|
| H00028 | Choriocarcinoma |
P03956
(related)
P08253 (related) |
| H00025 | Penile cancer |
P08253
(related)
P14780 (related) P35354 (related) |
| H00472 | Torg-Winchester syndrome |
P08253
(related)
|
| H00599 | 46,XX disorders of sex development (Disorders related to androgen excess) |
P11511
(related)
|
| H00794 | Aromatase excess syndrome |
P11511
(related)
|
| H00479 | Metaphyseal dysplasias |
P14780
(related)
P45452 (related) |
| H00017 | Esophageal cancer |
P35354
(related)
|
| H00046 | Cholangiocarcinoma |
P35354
(related)
|