PCIDB

Rubus spp.

Species

KNApSAcK Entry

Organism name Rubus spp.
Genus Rubus
Family Rosaceae
Kingdom Plantae

NCBI taxonomy

Entry

Linked NCBI taxonomy name Rubus
Linked NCBI taxonomy ID 23216
Linked level genus

Family

Family in NCBI taxonomy Rosaceae
ID 3745

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Viridiplantae
ID 33090

Plant class

Plant class rosids
ID 71275

Natural Activity

List (16)

Species Activity
Rubus spp. Antibacterial
Rubus spp. Antidote
Rubus spp. Antiinflammatory
Rubus spp. Antioxidant
Rubus spp. Antitumor
Rubus spp. Apoptotic
Rubus spp. Astringent
Rubus spp. Depurative
Rubus spp. Detoxicant
Rubus spp. Diaphoretic
Rubus spp. Diuretic
Rubus spp. Fungicide
Rubus spp. Hemostat
Rubus spp. Hypocholesterolemic
Rubus spp. Stimulant
Rubus spp. Tonic

Metabolite list (14)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE 		# of genes in
CTD interaction
/ related diseases 		KCF-S
cluster 		phytochemical
cluster 		figure
C00005180 External link 512 Kaempferol 3-glucoside-7-xyloside
No. 1 No. 15
C00002376 External link 512 Cyanidin 3-rutinoside
CHEMBL505251
C020386
3 / 0 / 1 No. 1 No. 15
C00006639 External link 512 Pelargonidin 3-rutinoside
No. 1 No. 15
C00006681 External link 512 Oxycoccicyanin
/ Peonidin 3-O-beta-D-glucopyranoside
CHEMBL1784263
No. 2 No. 15
C00006630 External link 512 Callistephin
/ Pelargonidin 3-O-beta-D-glucopyranoside
C078485
No. 2 No. 15
C00006644 External link 512 Pelargonidin 3-(2G-glucosylrutinoside)
No. 5 No. 15
C00006675 External link 512 Cyanidin 3-rutinoside-5-glucoside
No. 5 No. 15
C00006671 External link 512 Cyanidin 3-(2G-xylosylrutinoside)
No. 5 No. 15
C00009075 External link 512 Procyanidin B1
/ Epicatechin-(4beta->8)-catechin
CHEMBL38714
CHEMBL81753
CHEMBL504937
CHEMBL501490
CHEMBL447373
CHEMBL1253314
CHEMBL1590914
C479579
20 / 7 / 8 No. 16 No. 19
C00009071 External link 512 Procyanidin B3
/ Catechin-(4alpha->8)-catechin
CHEMBL38714
CHEMBL81753
CHEMBL504937
CHEMBL501490
CHEMBL447373
CHEMBL1253314
CHEMBL1590914
20 / 7 / 8 No. 16 No. 19
C00009076 External link 512 Procyanidin B5
/ Epicatechin-(4beta-6)-epicatechin
CHEMBL506487
CHEMBL502984
CHEMBL451115
No. 16 No. 19
C00002932 External link 512 Pedunculagin
CHEMBL292719
CHEMBL506204
1 / 1 / 0 No. 226 No. 81
C00002909 External link 512 Casuarictin
CHEMBL305099
CHEMBL446979
C073064
No. 226 No. 81
C00001188 External link 512 Isocitric acid
CHEMBL390356
CHEMBL539669
CHEMBL2338331
2 / 2 / 3 No. 7222

Human Protein / Gene in interactions

26 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
P10635 Cytochrome P450 2D6 Cytochrome P450 2D6 C00009071 C00009075 1 / 0
Q15139 Serine/threonine-protein kinase D1 Pkd C00009071 C00009075 0 / 0
P11712 Cytochrome P450 2C9 Cytochrome P450 2C9 C00009071 C00009075 0 / 1
P41743 Protein kinase C iota type Iota C00009071 C00009075 0 / 0
P24723 Protein kinase C eta type Eta C00009071 C00009075 1 / 0
P05771 Protein kinase C beta type Alpha C00009071 C00009075 0 / 0
P05129 Protein kinase C gamma type Alpha C00009071 C00009075 1 / 1
P18433 Receptor-type tyrosine-protein phosphatase alpha Receptor tyrosine-protein phosphatase C00009071 C00009075 0 / 0
P05177 Cytochrome P450 1A2 Cytochrome P450 1A2 C00009071 C00009075 0 / 0
Q99714 3-hydroxyacyl-CoA dehydrogenase type-2 Enzyme C00009071 C00009075 3 / 3
P23467 Receptor-type tyrosine-protein phosphatase beta Receptor tyrosine-protein phosphatase C00009071 C00009075 0 / 0
P16050 Arachidonate 15-lipoxygenase Enzyme C00009071 C00009075 0 / 0
P33261 Cytochrome P450 2C19 Cytochrome P450 2C19 C00009071 C00009075 1 / 1
Q05655 Protein kinase C delta type Delta C00009071 C00009075 0 / 0
Q05513 Protein kinase C zeta type Iota C00009071 C00009075 0 / 0
Q04759 Protein kinase C theta type Delta C00009071 C00009075 0 / 1
Q02156 Protein kinase C epsilon type Eta C00009071 C00009075 0 / 0
O94806 Serine/threonine-protein kinase D3 Pkd C00009071 C00009075 0 / 0
P17252 Protein kinase C alpha type Alpha C00009071 C00009075 0 / 0
P08684 Cytochrome P450 3A4 Cytochrome P450 3A4 C00009071 C00009075 0 / 1
O43521 Bcl-2-like protein 11 Unclassified protein C00002376 0 / 0
Q16611 Bcl-2 homologous antagonist/killer Unclassified protein C00002376 0 / 0
P00742 Coagulation factor X S1A C00002932 1 / 0
Q9GZT9 Egl nine homolog 1 Enzyme C00001188 1 / 1
Q07812 Apoptosis regulator BAX Unclassified protein C00002376 0 / 1
Q9C0B1 Alpha-ketoglutarate-dependent dioxygenase FTO Unclassified protein C00001188 1 / 2

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (10)

OMIM preferred title UniProt
#300438 17-beta-hydroxysteroid dehydrogenase x deficiency Q99714
#609535 Drug metabolism, poor, cyp2c19-related P33261
#608902 Drug metabolism, poor, cyp2d6-related P10635
#609820 Erythrocytosis, familial, 3; ecyt3 Q9GZT9
#227600 Factor x deficiency P00742
#612938 Growth retardation, developmental delay, coarse facies, and early death; gdfd Q9C0B1
#300705 Mental retardation, x-linked 17; mrx17 Q99714
#300220 Mental retardation, x-linked, syndromic 10; mrxs10 Q99714
#605361 Spinocerebellar ataxia 14; sca14 P05129
#601367 Stroke, ischemic P24723

KEGG DISEASE (12)

KEGG name UniProt
H00063 Spinocerebellar ataxia (SCA) P05129 (related)
H00036 Osteosarcoma P08684 (marker)
H01205 Coumarin resistance P11712 (related)
H01171 Poor drug metabolism (PM) P33261 (related)
H00408 Type I diabetes mellitus Q04759 (related)
H00020 Colorectal cancer Q07812 (related)
H00480 Non-syndromic X-linked mental retardation Q99714 (related)
H00658 Syndromic X-linked mental retardation Q99714 (related)
H00925 2-Methyl-3-hydroxybutyryl-CoA dehydrogenase (MHBD) deficiency Q99714 (related)
H00409 Type II diabetes mellitus Q9C0B1 (related)
H00926 Growth retardation, developmental delay, coarse facies, and early death Q9C0B1 (related)
H00236 Congenital polycythemia Q9GZT9 (related)