Allium sativum
Species
KNApSAcK Entry
| Organism name | Allium sativum |
|---|---|
| Genus | Allium |
| Family | Alliaceae |
| Kingdom | Plantae |
NCBI taxonomy
Entry
| Linked NCBI taxonomy name | Allium sativum |
|---|---|
| Linked NCBI taxonomy ID | 4682 |
| Linked level | species |
Family
| Family in NCBI taxonomy | Amaryllidaceae |
|---|---|
| ID | 4668 |
Kingdom (Superkingdom)
| Kingdom (Superkingdom) in NCBI taxonomy | Viridiplantae |
|---|---|
| ID | 33090 |
Plant class
| Plant class | Liliopsida |
|---|---|
| ID | 4447 |
Natural Activity
List (293)
| Species | Activity |
|---|---|
| Allium sativum L. | Abscess |
| Allium sativum L. | Acarifuge |
| Allium sativum L. | Acne |
| Allium sativum L. | Adenosis |
| Allium sativum L. | Aegilops |
| Allium sativum L. | Aging |
| Allium sativum L. | Alexeteric |
| Allium sativum L. | Allergy |
| Allium sativum L. | Alopecia |
| Allium sativum L. | Alterative |
| Allium sativum L. | Altitude Sickness |
| Allium sativum L. | Alzheimer's |
| Allium sativum L. | Amebiasis |
| Allium sativum L. | Amebicide |
| Allium sativum L. | Amenorrhea |
| Allium sativum L. | Analgesic |
| Allium sativum L. | Androgenic |
| Allium sativum L. | Anemia |
| Allium sativum L. | Anorexia |
| Allium sativum L. | Antiaflatoxin |
| Allium sativum L. | Antiaggregant |
| Allium sativum L. | Antiallergic |
| Allium sativum L. | Antiandrogenic |
| Allium sativum L. | Antiarthritic |
| Allium sativum L. | Antiatherogenic |
| Allium sativum L. | Antiatherosclerotic |
| Allium sativum L. | Antibacterial |
| Allium sativum L. | Anticancer |
| Allium sativum L. | Anticholinesterase |
| Allium sativum L. | Antidiabetic |
| Allium sativum L. | Antidote |
| Allium sativum L. | Antifertility |
| Allium sativum L. | Antigiardial |
| Allium sativum L. | Antiinflammatory |
| Allium sativum L. | Antiintegrase |
| Allium sativum L. | Antimycotic |
| Allium sativum L. | Antioxidant |
| Allium sativum L. | Antiprostaglandin |
| Allium sativum L. | Antipyretic |
| Allium sativum L. | Antirheumatic |
| Allium sativum L. | Antiseptic |
| Allium sativum L. | Antispasmodic |
| Allium sativum L. | Antistress |
| Allium sativum L. | Antithrombic |
| Allium sativum L. | Antithyroid |
| Allium sativum L. | Antitumor |
| Allium sativum L. | Antiulcer |
| Allium sativum L. | Antiviral |
| Allium sativum L. | Aphrodisiac |
| Allium sativum L. | Aphtha |
| Allium sativum L. | Appendicitis |
| Allium sativum L. | Arrhythmia |
| Allium sativum L. | Arthrosis |
| Allium sativum L. | Asthma |
| Allium sativum L. | Atherosclerosis |
| Allium sativum L. | Athlete's Foot |
| Allium sativum L. | Bacillus |
| Allium sativum L. | Bacteria |
| Allium sativum L. | Bite |
| Allium sativum L. | Boil |
| Allium sativum L. | Bronchiectasis |
| Allium sativum L. | Bronchosis |
| Allium sativum L. | Burn |
| Allium sativum L. | Callus |
| Allium sativum L. | Cancer |
| Allium sativum L. | Cancer, abdomen |
| Allium sativum L. | Cancer, bladder |
| Allium sativum L. | Cancer, breast |
| Allium sativum L. | Cancer, colon |
| Allium sativum L. | Cancer, esophagus |
| Allium sativum L. | Cancer, gland |
| Allium sativum L. | Cancer, lung |
| Allium sativum L. | Cancer, prostate |
| Allium sativum L. | Cancer, skin |
| Allium sativum L. | Cancer, stomach |
| Allium sativum L. | Cancer, uterus |
| Allium sativum L. | Candida |
| Allium sativum L. | Carbuncle |
| Allium sativum L. | Cardiopathy |
| Allium sativum L. | Cardiotonic |
| Allium sativum L. | Caries |
| Allium sativum L. | Carminative |
| Allium sativum L. | Catarrh |
| Allium sativum L. | Celiac |
| Allium sativum L. | Childbirth |
| Allium sativum L. | Cholecystosis |
| Allium sativum L. | Cholera |
| Allium sativum L. | Choleretic |
| Allium sativum L. | Chronic Fatigue |
| Allium sativum L. | Coccidiosis |
| Allium sativum L. | Cold |
| Allium sativum L. | Colic |
| Allium sativum L. | Colosis |
| Allium sativum L. | Congestion |
| Allium sativum L. | Constipation |
| Allium sativum L. | Convulsion |
| Allium sativum L. | Corn |
| Allium sativum L. | Cough |
| Allium sativum L. | Cramp |
| Allium sativum L. | Cryptococcus |
| Allium sativum L. | Cystosis |
| Allium sativum L. | Cytomegalovirus |
| Allium sativum L. | Deafness |
| Allium sativum L. | Debility |
| Allium sativum L. | Decongestant |
| Allium sativum L. | Dementia |
| Allium sativum L. | Dermatosis |
| Allium sativum L. | Detoxicant |
| Allium sativum L. | Diabetes |
| Allium sativum L. | Diaphoretic |
| Allium sativum L. | Diarrhea |
| Allium sativum L. | Digestive |
| Allium sativum L. | Diphtheria |
| Allium sativum L. | Diuretic |
| Allium sativum L. | Dropsy |
| Allium sativum L. | Dysentery |
| Allium sativum L. | Dysmenorrhea |
| Allium sativum L. | Dyspepsia |
| Allium sativum L. | Dyspnea |
| Allium sativum L. | Earache |
| Allium sativum L. | Edema |
| Allium sativum L. | Edemagenic |
| Allium sativum L. | Emmenagogue |
| Allium sativum L. | Enterosis |
| Allium sativum L. | Epigastrosis |
| Allium sativum L. | Epilepsy |
| Allium sativum L. | Escherichia |
| Allium sativum L. | Estrogenic |
| Allium sativum L. | Expectorant |
| Allium sativum L. | Felon |
| Allium sativum L. | Fever |
| Allium sativum L. | Fibrinolytic |
| Allium sativum L. | Fibroid |
| Allium sativum L. | Filaria |
| Allium sativum L. | Flu |
| Allium sativum L. | Fungicide |
| Allium sativum L. | Fungus |
| Allium sativum L. | Gangrene |
| Allium sativum L. | Gas |
| Allium sativum L. | Gastroenterosis |
| Allium sativum L. | Gastrosis |
| Allium sativum L. | Gastrotonic |
| Allium sativum L. | Giardia |
| Allium sativum L. | Glutathionigenic |
| Allium sativum L. | Gout |
| Allium sativum L. | Headache |
| Allium sativum L. | Helicobacter |
| Allium sativum L. | Hemorrhoid |
| Allium sativum L. | Hepatoprotective |
| Allium sativum L. | Hepatosis |
| Allium sativum L. | Hepatotoxicity(Acetaminophen) |
| Allium sativum L. | Herpes |
| Allium sativum L. | High Blood Pressure |
| Allium sativum L. | High Cholesterol |
| Allium sativum L. | High Triglycerides |
| Allium sativum L. | HIV |
| Allium sativum L. | Hookworm |
| Allium sativum L. | Hyperglycemic |
| Allium sativum L. | Hyperlipidemia |
| Allium sativum L. | Hyperperistalsis |
| Allium sativum L. | Hypocholesterolemic |
| Allium sativum L. | Hypoglycemia |
| Allium sativum L. | Hypoglycemic |
| Allium sativum L. | Hypolipidemic |
| Allium sativum L. | Hypoperistaltic |
| Allium sativum L. | Hypotensive |
| Allium sativum L. | Hypotention |
| Allium sativum L. | Hypotriglyceridemic |
| Allium sativum L. | Hypouricemic |
| Allium sativum L. | Hysteria |
| Allium sativum L. | Immunodepression |
| Allium sativum L. | Immunostimulant |
| Allium sativum L. | Impotence |
| Allium sativum L. | Induration |
| Allium sativum L. | Infection |
| Allium sativum L. | Inflammation |
| Allium sativum L. | Insanity |
| Allium sativum L. | Insectifuge |
| Allium sativum L. | Insomnia |
| Allium sativum L. | Insulin-Sparing |
| Allium sativum L. | Interleukenogenic |
| Allium sativum L. | Intermmittent Claudication |
| Allium sativum L. | Keratosis |
| Allium sativum L. | Lambliasis |
| Allium sativum L. | Larvicide |
| Allium sativum L. | Laryngosis |
| Allium sativum L. | Lead Poisoning |
| Allium sativum L. | Leishmaniasis |
| Allium sativum L. | Leprosy |
| Allium sativum L. | Leukemia |
| Allium sativum L. | Leukoderma |
| Allium sativum L. | Lipolytic |
| Allium sativum L. | Lumbago |
| Allium sativum L. | Lupus |
| Allium sativum L. | Lymphocytogenic |
| Allium sativum L. | Lymphoma |
| Allium sativum L. | Malaria |
| Allium sativum L. | Mange |
| Allium sativum L. | Melancholy |
| Allium sativum L. | Melanoma |
| Allium sativum L. | Meningosis |
| Allium sativum L. | Menopause |
| Allium sativum L. | Mucososis |
| Allium sativum L. | Mycosis |
| Allium sativum L. | Myocontractant |
| Allium sativum L. | Myofascities |
| Allium sativum L. | Myorelaxant |
| Allium sativum L. | Myosis |
| Allium sativum L. | Nausea |
| Allium sativum L. | Nephrosis |
| Allium sativum L. | Nervine |
| Allium sativum L. | Neuralgia |
| Allium sativum L. | Neuroblastoma |
| Allium sativum L. | Nicotinism |
| Allium sativum L. | NKC-Enhancer |
| Allium sativum L. | NO-Genic |
| Allium sativum L. | Odontosis |
| Allium sativum L. | Orexigenic |
| Allium sativum L. | Otosis |
| Allium sativum L. | Ovicide |
| Allium sativum L. | Oxytocic |
| Allium sativum L. | Pain |
| Allium sativum L. | Palpitation |
| Allium sativum L. | Paradentosis |
| Allium sativum L. | Paralysis |
| Allium sativum L. | Parasite |
| Allium sativum L. | Parasiticide |
| Allium sativum L. | Paratyphoid |
| Allium sativum L. | Paratyphus |
| Allium sativum L. | Periodontosis |
| Allium sativum L. | Pertussis |
| Allium sativum L. | Phagocytotic |
| Allium sativum L. | Pharyngosis |
| Allium sativum L. | Pinworm |
| Allium sativum L. | Pneumonia |
| Allium sativum L. | Poliomyelitis |
| Allium sativum L. | Polyp |
| Allium sativum L. | Protisticide |
| Allium sativum L. | Pulmonosis |
| Allium sativum L. | Pulposis |
| Allium sativum L. | Raynaud's |
| Allium sativum L. | Respirosis |
| Allium sativum L. | Rheumatism |
| Allium sativum L. | Rhinosis |
| Allium sativum L. | Ringworm |
| Allium sativum L. | Roundworm |
| Allium sativum L. | Rubefacient |
| Allium sativum L. | Salmonella |
| Allium sativum L. | Scabies |
| Allium sativum L. | Sciatica |
| Allium sativum L. | Sedative |
| Allium sativum L. | Senile Dementia |
| Allium sativum L. | Sepsis |
| Allium sativum L. | Shigella |
| Allium sativum L. | Sinusosis |
| Allium sativum L. | Snakebite |
| Allium sativum L. | Sore |
| Allium sativum L. | Sore Throat |
| Allium sativum L. | Spermicide |
| Allium sativum L. | Splenosis |
| Allium sativum L. | Streptococcus |
| Allium sativum L. | Stroke |
| Allium sativum L. | Swelling |
| Allium sativum L. | Syncope |
| Allium sativum L. | Tapeworm |
| Allium sativum L. | Thirst |
| Allium sativum L. | Thrombosis |
| Allium sativum L. | Tick |
| Allium sativum L. | Tonic |
| Allium sativum L. | Tonsilosis |
| Allium sativum L. | Trachoma |
| Allium sativum L. | Trichomonaisis |
| Allium sativum L. | Trypanosomiasis |
| Allium sativum L. | Tuberculosis |
| Allium sativum L. | Tumor |
| Allium sativum L. | Typhoid |
| Allium sativum L. | Typhus |
| Allium sativum L. | Ulcer |
| Allium sativum L. | Ulcus cruris |
| Allium sativum L. | UTI |
| Allium sativum L. | Vaginosis |
| Allium sativum L. | Varicosis |
| Allium sativum L. | Vasodilator |
| Allium sativum L. | Vermifuge |
| Allium sativum L. | Virus |
| Allium sativum L. | Vulnerary |
| Allium sativum L. | Wart |
| Allium sativum L. | Water Retention |
| Allium sativum L. | Wen |
| Allium sativum L. | Whitlow |
| Allium sativum L. | Worm |
| Allium sativum L. | Wound |
| Allium sativum L. | Yeast |
Metabolite list (10)
| KNApSAcK ID | name | ChEMBL link | CTD link |
# of proteins in
ChEMBL interaction / related OMIM / related KEGG DISEASE |
# of genes in
CTD interaction / related diseases |
KCF-S
cluster |
phytochemical
cluster |
figure |
|---|---|---|---|---|---|---|---|---|
C00002374
|
Chrysanthemin
/ Cyanidin 3-O-glucoside |
CHEMBL257839
CHEMBL1197952 |
C114438
|
1 / 0 / 1 | No. 2 | No. 15 |
|
|
|
C00006799
|
Cyanidin 3-(3'',6''-dimalonylglucoside)
|
No. 2 | No. 15 |
|
||||
|
C00006796
|
Cyanidin 3-(6''-malonylglucoside)
/ Cyanidin-3-O-(6-O-malonyl-beta-D-glucopyranoside) |
CHEMBL1173160
|
No. 2 | No. 15 |
|
|||
|
C00006795
|
Cyanidin 3-(3''-malonylglucoside)
|
No. 2 | No. 15 |
|
||||
|
C00034232
|
Se-Methylselenocysteine
|
CHEMBL62382
CHEMBL1472699 |
16 / 8 / 6 | No. 2513 |
|
|||
|
C00001336
|
Alliin
|
CHEMBL464166
CHEMBL2048655 |
3 / 5 / 3 | No. 2949 |
|
|||
|
C00001246
|
Dimethyl trisulfide
|
C054170
|
No. 4703 |
|
||||
|
C00001243
|
Diallyl disulfide
|
CHEMBL366603
|
C028009
|
11 / 10 / 9 | 33 / 5 | No. 6073 |
|
|
|
C00001244
|
Diallyl sulfide
|
CHEMBL170458
|
C038491
|
6 / 11 / 4 | 31 / 8 | No. 7212 |
|
|
|
C00001242
|
Allicin
|
CHEMBL359965
|
C006452
|
7 / 6 / 4 | 3 / 0 | No. 7944 |
|
Human Protein / Gene in interactions
31 ChEMBL Protein in interactions
| accession | description | class description | KNApSAcK metabolite in interactions |
# of diseases
(OMIM / KEGG) |
|---|---|---|---|---|
| P51170 | Amiloride-sensitive sodium channel subunit gamma | Unclassified protein | C00001242 C00001243 C00001244 C00001336 | 2 / 3 |
| P51168 | Amiloride-sensitive sodium channel subunit beta | Unclassified protein | C00001242 C00001243 C00001244 C00001336 | 3 / 3 |
| P37088 | Amiloride-sensitive sodium channel subunit alpha | NA | C00001242 C00001243 C00001244 C00001336 | 2 / 2 |
| O75762 | Transient receptor potential cation channel subfamily A member 1 | Unclassified protein | C00001242 C00001243 C00001244 | 1 / 0 |
| P16050 | Arachidonate 15-lipoxygenase | Enzyme | C00001243 C00034232 | 0 / 0 |
| P08684 | Cytochrome P450 3A4 | Cytochrome P450 3A4 | C00001243 C00034232 | 0 / 1 |
| P28482 | Mitogen-activated protein kinase 1 | Erk | C00034232 | 0 / 0 |
| P08183 | Multidrug resistance protein 1 | drug | C00001244 | 1 / 0 |
| P11712 | Cytochrome P450 2C9 | Cytochrome P450 2C9 | C00034232 | 0 / 1 |
| P11473 | Vitamin D3 receptor | NR1I1 | C00001243 | 2 / 3 |
| P07858 | Cathepsin B | C1A | C00001242 | 0 / 1 |
| P00352 | Retinal dehydrogenase 1 | Enzyme | C00001243 | 0 / 0 |
| Q16665 | Hypoxia-inducible factor 1-alpha | Transcription Factor | C00034232 | 0 / 0 |
| P07711 | Cathepsin L1 | C1A | C00001242 | 0 / 0 |
| Q8NER1 | Transient receptor potential cation channel subfamily V member 1 | TRPV (Vanilloid) | C00001242 | 0 / 0 |
| P16473 | Thyrotropin receptor | Glycohormone receptor | C00034232 | 3 / 2 |
| P05177 | Cytochrome P450 1A2 | Cytochrome P450 1A2 | C00034232 | 0 / 0 |
| P28907 | ADP-ribosyl cyclase 1 | Enzyme | C00002374 | 0 / 1 |
| P15428 | 15-hydroxyprostaglandin dehydrogenase [NAD(+)] | Enzyme | C00001243 | 2 / 2 |
| Q96QE3 | ATPase family AAA domain-containing protein 5 | Unclassified protein | C00034232 | 0 / 0 |
| P19838 | Nuclear factor NF-kappa-B p105 subunit | Transcription Factor | C00034232 | 0 / 0 |
| Q16773 | Kynurenine--oxoglutarate transaminase 1 | Enzyme | C00034232 | 0 / 0 |
| P33261 | Cytochrome P450 2C19 | Cytochrome P450 2C19 | C00034232 | 1 / 1 |
| P49798 | Regulator of G-protein signaling 4 | Unclassified protein | C00034232 | 2 / 0 |
| P05181 | Cytochrome P450 2E1 | Cytochrome P450 2E1 | C00001243 | 0 / 0 |
| P27695 | DNA-(apurinic or apyrimidinic site) lyase | Enzyme | C00001243 | 0 / 0 |
| Q16236 | Nuclear factor erythroid 2-related factor 2 | Unclassified protein | C00034232 | 0 / 0 |
| Q96KQ7 | Histone-lysine N-methyltransferase EHMT2 | Enzyme | C00034232 | 0 / 0 |
| Q99700 | Ataxin-2 | Unclassified protein | C00034232 | 1 / 1 |
| Q16637 | Survival motor neuron protein | Unclassified protein | C00001244 | 4 / 1 |
| P10635 | Cytochrome P450 2D6 | Cytochrome P450 2D6 | C00034232 | 1 / 0 |
54 Gene in CTD interactions
| gene | gene name | gene description | KNApSAcK metabolite in interactions |
|---|---|---|---|
| 5243 | ABCB1, ABC20, CD243, CLCS, GP170, MDR1, P-GP, PGY1 | ATP-binding cassette, sub-family B (MDR/TAP), member 1 (EC:3.6.3.44) |
C00001243
C00001244
|
| 5599 | MAPK8, JNK, JNK-46, JNK1, JNK1A2, JNK21B1/2, PRKM8, SAPK1, SAPK1c | mitogen-activated protein kinase 8 (EC:2.7.11.24) |
C00001243
C00001244
|
| 1571 | CYP2E1, CPE1, CYP2E, P450-J, P450C2E | cytochrome P450, family 2, subfamily E, polypeptide 1 (EC:1.14.13.n7) |
C00001243
C00001244
|
| 361523 |
C00001243
C00001244
|
||
| 4363 | ABCC1, ABC29, ABCC, GS-X, MRP, MRP1 | ATP-binding cassette, sub-family C (CFTR/MRP), member 1 |
C00001243
C00001244
|
| 8714 | ABCC3, ABC31, EST90757, MLP2, MOAT-D, MRP3, cMOAT2 | ATP-binding cassette, sub-family C (CFTR/MRP), member 3 |
C00001243
C00001244
|
| 10257 | ABCC4, EST170205, MOAT-B, MOATB, MRP4 | ATP-binding cassette, sub-family C (CFTR/MRP), member 4 |
C00001243
C00001244
|
| 24300 |
C00001243
C00001244
|
||
| 1548 | CYP2A6, CPA6, CYP2A, CYP2A3, CYPIIA6, P450C2A, P450PB | cytochrome P450, family 2, subfamily A, polypeptide 6 (EC:1.14.14.1) |
C00001243
C00001244
|
| 596 | BCL2, Bcl-2, PPP1R50 | B-cell CLL/lymphoma 2 |
C00001243
C00001244
|
| 836 | CASP3, CPP32, CPP32B, SCA-1 | caspase 3, apoptosis-related cysteine peptidase (EC:3.4.22.56) |
C00001243
C00001244
|
| 842 | CASP9, APAF-3, APAF3, ICE-LAP6, MCH6, PPP1R56 | caspase 9, apoptosis-related cysteine peptidase (EC:3.4.22.62) |
C00001243
C00001244
|
| 1543 | CYP1A1, AHH, AHRR, CP11, CYP1, P1-450, P450-C, P450DX | cytochrome P450, family 1, subfamily A, polypeptide 1 (EC:1.14.14.1) |
C00001243
C00001244
|
| 3725 | JUN, AP-1, AP1, c-Jun | jun proto-oncogene |
C00001243
|
| 999 | CDH1, Arc-1, CD324, CDHE, ECAD, LCAM, UVO | cadherin 1, type 1, E-cadherin (epithelial) |
C00001243
|
| 983 | CDK1, CDC2, CDC28A, P34CDC2 | cyclin-dependent kinase 1 (EC:2.7.11.23 2.7.11.22) |
C00001243
|
| 9075 | CLDN2 | claudin 2 |
C00001243
|
| 1365 | CLDN3, C7orf1, CPE-R2, CPETR2, HRVP1, RVP1 | claudin 3 |
C00001243
|
| 1364 | CLDN4, CPE-R, CPER, CPETR, CPETR1, WBSCR8, hCPE-R | claudin 4 |
C00001243
|
| 7122 | CLDN5, AWAL, BEC1, CPETRL1, TMVCF | claudin 5 |
C00001243
|
| 1499 | CTNNB1, CTNNB, MRD19, armadillo | catenin (cadherin-associated protein), beta 1, 88kDa |
C00001243
|
| 857 | CAV1, BSCL3, CGL3, MSTP085, PPH3, VIP21, CAV | caveolin 1, caveolae protein, 22kDa |
C00001243
|
| 467 | ATF3 | activating transcription factor 3 |
C00001243
|
| 368 | ABCC6, ABC34, ARA, EST349056, GACI2, MLP1, MOAT-E, MOATE, MRP6, PXE, PXE1, URG7 | ATP-binding cassette, sub-family C (CFTR/MRP), member 6 |
C00001243
|
| 3383 | ICAM1, BB2, CD54, P3.58 | intercellular adhesion molecule 1 |
C00001242
|
| 7442 | TRPV1, VR1 | transient receptor potential cation channel, subfamily V, member 1 |
C00001242
|
| 9518 | GDF15, GDF-15, MIC-1, MIC1, NAG-1, PDF, PLAB, PTGFB | growth differentiation factor 15 |
C00001243
|
| 891 | CCNB1, CCNB | cyclin B1 |
C00001243
|
| 7124 | TNF, DIF, TNF-alpha, TNFA, TNFSF2 | tumor necrosis factor |
C00001242
|
| 4313 | MMP2, CLG4, CLG4A, MMP-II, MONA, TBE-1 | matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase) (EC:3.4.24.24) |
C00001243
|
| 4318 | MMP9, CLG4B, GELB, MANDP2, MMP-9 | matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase) (EC:3.4.24.35) |
C00001243
|
| 4846 | NOS3, ECNOS, eNOS | nitric oxide synthase 3 (endothelial cell) (EC:1.14.13.39) |
C00001243
|
| 6615 | SNAI1, SLUGH2, SNA, SNAH, SNAIL, SNAIL1, dJ710H13.1 | snail family zinc finger 1 |
C00001243
|
| 7076 | TIMP1, CLGI, EPA, EPO, HCI, TIMP | TIMP metallopeptidase inhibitor 1 |
C00001243
|
| 7077 | TIMP2, CSC-21K, DDC8 | TIMP metallopeptidase inhibitor 2 |
C00001243
|
| 7157 | TP53, BCC7, LFS1, P53, TRP53 | tumor protein p53 |
C00001243
|
| 581 | BAX, BCL2L4 | BCL2-associated X protein |
C00001244
|
| 330 | BIRC3, AIP1, API2, CIAP2, HAIP1, HIAP1, MALT2, MIHC, RNF49, c-IAP2 | baculoviral IAP repeat containing 3 |
C00001244
|
| 332 | BIRC5, API4, EPR-1 | baculoviral IAP repeat containing 5 |
C00001244
|
| 837 | CASP4, ICE(rel)II, ICEREL-II, ICH-2, Mih1/TX, TX | caspase 4, apoptosis-related cysteine peptidase (EC:3.4.22.57) |
C00001244
|
| 831 | CAST, BS-17 | calpastatin |
C00001244
|
| 1026 | CDKN1A, CAP20, CDKN1, CIP1, MDA-6, P21, SDI1, WAF1, p21CIP1 | cyclin-dependent kinase inhibitor 1A (p21, Cip1) |
C00001244
|
| 1555 | CYP2B6, CPB6, CYP2B, CYP2B7, CYP2B7P, CYPIIB6, EFVM, IIB1, P450 | cytochrome P450, family 2, subfamily B, polypeptide 6 (EC:1.14.14.1) |
C00001244
|
| 56616 | DIABLO, DFNA64, SMAC | diablo, IAP-binding mitochondrial protein |
C00001244
|
| 355 | FAS, ALPS1A, APO-1, APT1, CD95, FAS1, FASTM, TNFRSF6 | Fas cell surface death receptor |
C00001244
|
| 1647 | GADD45A, DDIT1, GADD45 | growth arrest and DNA-damage-inducible, alpha |
C00001244
|
| 2950 | GSTP1, DFN7, FAEES3, GST3, GSTP, PI | glutathione S-transferase pi 1 (EC:2.5.1.18) |
C00001244
|
| 10397 | NDRG1, CAP43, CMT4D, DRG-1, DRG1, GC4, HMSNL, NDR1, NMSL, PROXY1, RIT42, RTP, TARG1, TDD5 | N-myc downstream regulated 1 |
C00001244
|
| 1728 | NQO1, DHQU, DIA4, DTD, NMOR1, NMORI, QR1 | NAD(P)H dehydrogenase, quinone 1 (EC:1.6.5.2) |
C00001244
|
| 5465 | PPARA, NR1C1, PPAR, PPARalpha, hPPAR | peroxisome proliferator-activated receptor alpha |
C00001244
|
| 5743 | PTGS2, COX-2, COX2, GRIPGHS, PGG/HS, PGHS-2, PHS-2, hCox-2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) (EC:1.14.99.1) |
C00001244
|
| 6720 | SREBF1, SREBP-1c, SREBP1, bHLHd1 | sterol regulatory element binding transcription factor 1 |
C00001244
|
| 7296 | TXNRD1, GRIM-12, TR, TR1, TRXR1, TXNR | thioredoxin reductase 1 (EC:1.8.1.9) |
C00001244
|
| 331 | XIAP, API3, BIRC4, IAP-3, ILP1, MIHA, XLP2, hIAP-3, hIAP3 | X-linked inhibitor of apoptosis |
C00001244
|
Related Diseases
Diseases related to proteins in ChEMBL interactions
OMIM (23)
| OMIM | preferred title | UniProt |
|---|---|---|
| #211400 | Bronchiectasis with or without elevated sweat chloride 1; besc1 |
P51168
|
| #613021 | Bronchiectasis with or without elevated sweat chloride 2; besc2 |
P37088
|
| #613071 | Bronchiectasis with or without elevated sweat chloride 3; besc3 |
P51170
|
| #119900 | Digital clubbing, isolated congenital |
P15428
|
| #609535 | Drug metabolism, poor, cyp2c19-related |
P33261
|
| #608902 | Drug metabolism, poor, cyp2d6-related |
P10635
|
| #615040 | Episodic pain syndrome, familial, 1; feps1 |
O75762
|
| #603373 | Hyperthyroidism, familial gestational |
P16473
|
| #609152 | Hyperthyroidism, nonautoimmune |
P16473
|
| #259100 | Hypertrophic osteoarthropathy, primary, autosomal recessive, 1; phoar1 |
P15428
|
| #275200 | Hypothyroidism, congenital, nongoitrous, 1; chng1 |
P16473
|
| #612244 | Inflammatory bowel disease 13; ibd13 |
P08183
|
| #177200 | Liddle syndrome |
P51168
P51170 |
| #607948 | Mycobacterium tuberculosis, susceptibility to |
P11473
|
| #264350 | Pseudohypoaldosteronism, type i, autosomal recessive; pha1b |
P37088
P51168 |
| #604906 | Schizophrenia 9; sczd9 |
P49798
|
| #181500 | Schizophrenia; sczd |
P49798
|
| #253300 | Spinal muscular atrophy, type i; sma1 |
Q16637
|
| #253550 | Spinal muscular atrophy, type ii; sma2 |
Q16637
|
| #253400 | Spinal muscular atrophy, type iii; sma3 |
Q16637
|
| #271150 | Spinal muscular atrophy, type iv; sma4 |
Q16637
|
| #183090 | Spinocerebellar ataxia 2; sca2 |
Q99700
|
| #277440 | Vitamin d-dependent rickets, type 2a; vddr2a |
P11473
|
KEGG DISEASE (17)
| KEGG | name | UniProt |
|---|---|---|
| H00932 | Tropical calcific pancreatitis |
P07858
(related)
|
| H00036 | Osteosarcoma |
P08684
(marker)
|
| H00342 | Tuberculosis |
P11473
(related)
|
| H00784 | Localized autosomal recessive hypotrichosis |
P11473
(related)
|
| H01143 | Vitamin D-dependent rickets |
P11473
(related)
|
| H01205 | Coumarin resistance |
P11712
(related)
|
| H00457 | Primary hypertrophic osteoarthropathy (PHO) |
P15428
(related)
|
| H01246 | Isolated congenital nail clubbing (ICNC) |
P15428
(related)
|
| H00250 | Congenital nongoitrous hypothyroidism (CHNG) |
P16473
(related)
|
| H01269 | Congenital hyperthyroidism |
P16473
(related)
|
| H00005 | Chronic lymphocytic leukemia (CLL) |
P28907
(marker)
|
| H01171 | Poor drug metabolism (PM) |
P33261
(related)
|
| H00243 | Hyperkalemic distal renal tubular acidosis (RTA type 4) |
P37088
(related)
P51168 (related) P51170 (related) |
| H00892 | Bronchiectasis with or without elevated sweat chloride |
P37088
(related)
P51168 (related) P51170 (related) |
| H00242 | Liddle syndrome |
P51168
(related)
P51170 (related) |
| H00455 | Spinal muscular atrophy (SMA) |
Q16637
(related)
|
| H00063 | Spinocerebellar ataxia (SCA) |
Q99700
(related)
|
Diseases related to CTD interactions
13 disease in interactions with metabolites
| MESH or OMIM | name |
KNApSAcK
metabolite |
|---|---|---|
| D000230 | Adenocarcinoma |
C00001243
|
| D003110 | Colonic Neoplasms |
C00001243
|
| D007674 | Kidney Diseases |
C00001243
|
| D009369 | Neoplasms |
C00001243
|
| D011471 | Prostatic Neoplasms |
C00001243
|
| D001943 | Breast Neoplasms |
C00001244
|
| D056486 | Drug-Induced Liver Injury |
C00001244
|
| D005235 | Fatty Liver, Alcoholic |
C00001244
|
| D006525 | Hepatitis, Viral, Human |
C00001244
|
| D006965 | Hyperplasia |
C00001244
|
| D008113 | Liver Neoplasms |
C00001244
|
| D009404 | Nephrotic Syndrome |
C00001244
|
| D012878 | Skin Neoplasms |
C00001244
|