Species

KNApSAcK Entry

Organism name Arum maculatum
Genus Arum
Family Araceae
Kingdom Plantae

NCBI taxonomy

Entry

Linked NCBI taxonomy name Arum maculatum
Linked NCBI taxonomy ID 4458
Linked level species

Family

Family in NCBI taxonomy Araceae
ID 4454

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Viridiplantae
ID 33090

Plant class

Plant class Liliopsida
ID 4447

Metabolite list (5)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE
# of genes in
CTD interaction
/ related diseases
KCF-S
cluster
phytochemical
cluster
figure
C00002376 External link 512 Cyanidin 3-rutinoside
CHEMBL505251
C020386
3 / 0 / 1 No. 1 No. 15
C00022905 External link 512 Lycophyll
/ psi,psi-Carotene-16,16'-diol
No. 97 No. 59
C00001254 External link 512 Heptan-2-one
CHEMBL18893
C011917
1 / 0 No. 1738
C00001418 External link 512 Indole
CHEMBL15844
C030374
13 / 5 / 6 6 / 0 No. 3673
C00001413 External link 512 Hexylamine
CHEMBL1320720
C007940
3 / 0 / 1 No. 5177

Human Protein / Gene in interactions

19 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
Q07812 Apoptosis regulator BAX Unclassified protein C00002376 0 / 1
P00918 Carbonic anhydrase 2 Lyase C00001418 1 / 2
Q00535 Cyclin-dependent kinase 5 Cdk5 C00001418 0 / 0
Q15078 Cyclin-dependent kinase 5 activator 1 REG serine/threonine protein kinase family C00001418 0 / 0
P23280 Carbonic anhydrase 6 Lyase C00001418 0 / 0
P10145 Interleukin-8 Secreted protein C00001413 0 / 0
P00915 Carbonic anhydrase 1 Lyase C00001418 0 / 0
Q16611 Bcl-2 homologous antagonist/killer Unclassified protein C00002376 0 / 0
O43521 Bcl-2-like protein 11 Unclassified protein C00002376 0 / 0
P04150 Glucocorticoid receptor NR3C1 C00001413 0 / 1
P55263 Adenosine kinase Enzyme C00001418 1 / 0
Q16236 Nuclear factor erythroid 2-related factor 2 Unclassified protein C00001413 0 / 0
P23141 Liver carboxylesterase 1 Enzyme C00001418 0 / 0
P22748 Carbonic anhydrase 4 Lyase C00001418 1 / 1
P05107 Integrin beta-2 Membrane receptor C00001418 1 / 1
P05362 Intercellular adhesion molecule 1 Adhesion C00001418 1 / 2
P20701 Integrin alpha-L Membrane receptor C00001418 0 / 0
P49840 Glycogen synthase kinase-3 alpha Gsk C00001418 0 / 0
P49841 Glycogen synthase kinase-3 beta Gsk C00001418 0 / 0

7 Gene in CTD interactions

gene gene name gene description KNApSAcK metabolite in interactions
2950 GSTP1, DFN7, FAEES3, GST3, GSTP, PI glutathione S-transferase pi 1 (EC:2.5.1.18) C00001254
196 AHR, bHLHe76 aryl hydrocarbon receptor C00001418
405 ARNT, HIF-1-beta, HIF-1beta, HIF1-beta, HIF1B, HIF1BETA, TANGO, bHLHe2 aryl hydrocarbon receptor nuclear translocator C00001418
4157 MC1R, CMM5, MSH-R, SHEP2 melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor) C00001418
4159 MC3R, BMIQ9, MC3, MC3-R, OB20, OQTL melanocortin 3 receptor C00001418
4160 MC4R melanocortin 4 receptor C00001418
4161 MC5R, MC2 melanocortin 5 receptor C00001418

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (5)

OMIM preferred title UniProt
#614300 Hypermethioninemia due to adenosine kinase deficiency P55263
#116920 Leukocyte adhesion deficiency, type i; lad P05107
#611162 Malaria, susceptibility to P05362
#259730 Osteopetrosis, autosomal recessive 3; optb3 P00918
#600852 Retinitis pigmentosa 17; rp17 P22748

KEGG DISEASE (8)

KEGG name UniProt
H00241 Combined proximal and distal renal tubular acidosis (RTA type 3) P00918 (related)
H00436 Osteopetrosis P00918 (related)
H00599 46,XX disorders of sex development (Disorders related to androgen excess) P04150 (related)
H00099 Leukocyte adhesion deficiency (LAD) P05107 (related)
H00083 Allograft rejection P05362 (related)
H00080 Systemic lupus erythematosus P05362 (marker)
H00527 Retinitis pigmentosa (RP) P22748 (related)
H00020 Colorectal cancer Q07812 (related)