PCIDB

Maytenus krukovii

Species

KNApSAcK Entry

Organism name Maytenus krukovii
Genus Maytenus
Family Celastraceae
Kingdom Plantae

NCBI taxonomy

Entry

Linked NCBI taxonomy name Maytenus
Linked NCBI taxonomy ID 123430
Linked level genus

Family

Family in NCBI taxonomy Celastraceae
ID 4305

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Viridiplantae
ID 33090

Plant class

Plant class rosids
ID 71275

Metabolite list (4)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE 		# of genes in
CTD interaction
/ related diseases 		KCF-S
cluster 		phytochemical
cluster 		figure
C00050373 External link 512 Krukovine B
/ (+)-Krukovine B
No. 13 No. 51
C00050372 External link 512 Krukovine A
/ (+)-Krukovine A
No. 13 No. 51
C00001405 External link 512 D-Cathine
CHEMBL61006
CHEMBL136560
CHEMBL1412041
CHEMBL1574804
CHEMBL1616525
CHEMBL1788114
CHEMBL2092846
13 / 13 / 13 No. 2149 No. 9
C00001406 External link 512 D-Cathinone
CHEMBL1124
CHEMBL2104047
1 / 0 / 0 No. 2578 No. 9

Human Protein / Gene in interactions

14 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
P10635 Cytochrome P450 2D6 Cytochrome P450 2D6 C00001405 1 / 0
P02545 Prelamin-A/C Unclassified protein C00001405 11 / 10
P11712 Cytochrome P450 2C9 Cytochrome P450 2C9 C00001405 0 / 1
Q16665 Hypoxia-inducible factor 1-alpha Transcription Factor C00001405 0 / 0
Q92830 Histone acetyltransferase KAT2A Enzyme C00001405 0 / 0
P08913 Alpha-2A adrenergic receptor Adrenergic receptor C00001405 0 / 0
P35348 Alpha-1A adrenergic receptor Adrenergic receptor C00001405 0 / 0
P05177 Cytochrome P450 1A2 Cytochrome P450 1A2 C00001405 0 / 0
P33261 Cytochrome P450 2C19 Cytochrome P450 2C19 C00001405 1 / 1
P08684 Cytochrome P450 3A4 Cytochrome P450 3A4 C00001405 0 / 1
B2RXH2 Lysine-specific demethylase 4E Enzyme C00001405 0 / 0
P35368 Alpha-1B adrenergic receptor Adrenergic receptor C00001405 0 / 0
P25100 Alpha-1D adrenergic receptor Adrenergic receptor C00001405 0 / 0
O94925 Glutaminase kidney isoform, mitochondrial Enzyme C00001406 0 / 0

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (13)

OMIM preferred title UniProt
#115200 Cardiomyopathy, dilated, 1a; cmd1a P02545
#212112 Cardiomyopathy, dilated, with hypergonadotropic hypogonadism P02545
#605588 Charcot-marie-tooth disease, axonal, type 2b1; cmt2b1 P02545
#609535 Drug metabolism, poor, cyp2c19-related P33261
#608902 Drug metabolism, poor, cyp2d6-related P10635
#181350 Emery-dreifuss muscular dystrophy 2, autosomal dominant; edmd2 P02545
#610140 Heart-hand syndrome, slovenian type P02545
#176670 Hutchinson-gilford progeria syndrome; hgps P02545
#151660 Lipodystrophy, familial partial, type 2; fpld2 P02545
#248370 Mandibuloacral dysplasia with type a lipodystrophy; mada P02545
#613205 Muscular dystrophy, congenital, lmna-related P02545
#159001 Muscular dystrophy, limb-girdle, type 1b; lgmd1b P02545
#275210 Restrictive dermopathy, lethal P02545

KEGG DISEASE (13)

KEGG name UniProt
H00264 Charcot-Marie-Tooth disease (CMT) P02545 (related)
H00294 Dilated cardiomyopathy (DCM) P02545 (related)
H00420 Familial partial lipodystrophy (FPL) P02545 (related)
H00563 Emery-Dreifuss muscular dystrophy P02545 (related)
H00590 Congenital muscular dystrophies (CMD/MDC) P02545 (related)
H00593 Limb-girdle muscular dystrophy (LGMD) P02545 (related)
H00601 Hutchinson-Gilford progeria syndrome P02545 (related)
H00663 Restrictive dermopathy P02545 (related)
H00665 Mandibuloacral dysplasia P02545 (related)
H01216 Left ventricular noncompaction (LVNC) P02545 (related)
H00036 Osteosarcoma P08684 (marker)
H01205 Coumarin resistance P11712 (related)
H01171 Poor drug metabolism (PM) P33261 (related)