Species

KNApSAcK Entry

Organism name Solanum tuberosum L.
Genus Solanum
Family Solanaceae
Kingdom Plantae

NCBI taxonomy

Entry

Linked NCBI taxonomy name Solanum tuberosum
Linked NCBI taxonomy ID 4113
Linked level species

Family

Family in NCBI taxonomy Solanaceae
ID 4070

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Viridiplantae
ID 33090

Plant class

Plant class asterids
ID 71274

Natural Activity

List (37)

Species Activity
Solanum tuberosum L. Alterative
Solanum tuberosum L. Alterative
Solanum tuberosum L. Analgesic
Solanum tuberosum L. Analgesic
Solanum tuberosum L. Antibacterial
Solanum tuberosum L. Antiinflammatory
Solanum tuberosum L. Antiseptic
Solanum tuberosum L. Antiseptic
Solanum tuberosum L. Antispasmodic
Solanum tuberosum L. Antispasmodic
Solanum tuberosum L. Antiulcer
Solanum tuberosum L. Bactericide
Solanum tuberosum L. Cardiotonic
Solanum tuberosum L. Cardiotonic
Solanum tuberosum L. Collyrium
Solanum tuberosum L. Diuretic
Solanum tuberosum L. Diuretic
Solanum tuberosum L. Emetic
Solanum tuberosum L. Emetic
Solanum tuberosum L. Emollient
Solanum tuberosum L. Fungicide
Solanum tuberosum L. Fungicide
Solanum tuberosum L. Hemostat
Solanum tuberosum L. Hypoglycemic
Solanum tuberosum L. Hypoglycemic
Solanum tuberosum L. Hypotensive
Solanum tuberosum L. Hypotensive
Solanum tuberosum L. Lactagogue
Solanum tuberosum L. Lactagogue
Solanum tuberosum L. Myotropic
Solanum tuberosum L. Myotropic
Solanum tuberosum L. Narcotic
Solanum tuberosum L. Narcotic
Solanum tuberosum L. Orexigenic
Solanum tuberosum L. Orexigenic
Solanum tuberosum L. Pectoral
Solanum tuberosum L. Pectoral

Metabolite list (8)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE
# of genes in
CTD interaction
/ related diseases
KCF-S
cluster
phytochemical
cluster
figure
C00005413 External link 512 Rutin
/ Birutan
/ 3-Rutinosylquercetin
/ Quercetin 3-O-rutinoside
/ (+)-Quercetin 3-O-rutinoside
/ Quercetin 3-O-beta-rutinoside
/ (+)-Quercetin 3-O-beta-rutinoside
/ 3,3',4',5,7-Pentahydroxyflavone 3-rutinoside
/ Quercetin 3-O-alpha-L-rhamnopyranosyl-(1->6)-beta-D-glucopyranoside
CHEMBL32579
CHEMBL310754
CHEMBL182108
CHEMBL226335
CHEMBL502782
CHEMBL1436093
CHEMBL1532989
D012431
25 / 18 / 16 29 / 8 No. 1 No. 15
C00005373 External link 512 Hirsutrin
/ Isoquercetin
/ Isoquercetrin
/ (-)-Isoquercetrin
/ Quercetin 3-glucoside
/ Quercetin 3-O-beta-D-glucoside
/ Quercetin-3-O-beta-D-glucopyranoside
/ Quercetin 3-O-beta-D-glucopyranoside
/ (-)-Quercetin-3-O-beta-D-glucopyranoside
CHEMBL33027
CHEMBL309323
CHEMBL250450
CHEMBL251254
CHEMBL457304
CHEMBL1098724
CHEMBL2337335
CHEMBL2337336
38 / 43 / 34 No. 2 No. 15
C00003672 External link 512 Sitosterol
/ beta-sitosterl
/ (-)-beta-Sitosterol
/ Stigmast-5-en-3beta-ol
CHEMBL221542
CHEMBL1398443
CHEMBL1875388
17 / 19 / 12 No. 53 No. 11
C00007320 External link 512 24-Methylenelophenol
No. 111 No. 11
C00002724 External link 512 Heriguard
/ Chlorogenic acid
/ 3-O-Caffeoylquinic acid
CHEMBL284616
CHEMBL230481
CHEMBL249450
CHEMBL1332980
CHEMBL1394423
CHEMBL1419611
CHEMBL1473644
CHEMBL1552319
D002726
30 / 19 / 22 37 / 9 No. 314 No. 6
C00001408 External link 512 Dopamine
CHEMBL59
D004298
69 / 40 / 56 51 / 52 No. 1114 No. 6
C00001424 External link 512 Norepinephrine
/ L-Noradrenaline
/ (-)-Norepinephrine
CHEMBL432
CHEMBL18824
CHEMBL1437
CHEMBL2311152
D009638
50 / 33 / 35 36 / 90 No. 3197
C00037562 External link 512 Normetanephrine
CHEMBL774
CHEMBL1559460
D009647
8 / 2 / 3 1 / 2 No. 3197

Human Protein / Gene in interactions

145 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
P08684 Cytochrome P450 3A4 Cytochrome P450 3A4 C00001408 C00001424 C00002724 C00003672 C00005413 C00037562 0 / 1
Q96KQ7 Histone-lysine N-methyltransferase EHMT2 Enzyme C00001408 C00001424 C00002724 C00005373 C00005413 C00037562 0 / 0
P27695 DNA-(apurinic or apyrimidinic site) lyase Enzyme C00001408 C00001424 C00002724 C00005373 C00005413 0 / 0
B2RXH2 Lysine-specific demethylase 4E Enzyme C00001408 C00001424 C00002724 C00005373 C00005413 0 / 0
P10635 Cytochrome P450 2D6 Cytochrome P450 2D6 C00001408 C00002724 C00003672 C00037562 1 / 0
P10636 Microtubule-associated protein tau Unclassified protein C00001408 C00001424 C00005373 C00005413 4 / 3
Q9NUW8 Tyrosyl-DNA phosphodiesterase 1 Enzyme C00001408 C00001424 C00002724 C00003672 1 / 1
Q9UBT6 DNA polymerase kappa Enzyme C00001408 C00001424 C00005373 C00005413 0 / 0
P33261 Cytochrome P450 2C19 Cytochrome P450 2C19 C00001408 C00002724 C00003672 C00037562 1 / 1
P05177 Cytochrome P450 1A2 Cytochrome P450 1A2 C00001408 C00002724 C00003672 C00037562 0 / 0
P28482 Mitogen-activated protein kinase 1 Erk C00001408 C00001424 C00005373 C00005413 0 / 0
P14679 Tyrosinase Oxidoreductase C00001408 C00003672 C00005373 C00005413 4 / 2
P11712 Cytochrome P450 2C9 Cytochrome P450 2C9 C00001408 C00002724 C00003672 C00037562 0 / 1
P18825 Alpha-2C adrenergic receptor Adrenergic receptor C00001408 C00001424 C00005373 C00005413 0 / 0
O94925 Glutaminase kidney isoform, mitochondrial Enzyme C00001408 C00001424 C00002724 C00005373 0 / 0
P35354 Prostaglandin G/H synthase 2 Oxidoreductase C00002724 C00005373 C00005413 0 / 3
P39748 Flap endonuclease 1 Enzyme C00001408 C00001424 C00005373 0 / 0
P08913 Alpha-2A adrenergic receptor Adrenergic receptor C00001408 C00001424 C00005413 0 / 0
Q99714 3-hydroxyacyl-CoA dehydrogenase type-2 Enzyme C00001408 C00002724 C00005413 3 / 3
P06746 DNA polymerase beta Enzyme C00003672 C00005373 C00005413 0 / 0
Q9NR56 Muscleblind-like protein 1 Unclassified protein C00001424 C00005373 C00005413 1 / 0
P16473 Thyrotropin receptor Glycohormone receptor C00002724 C00003672 3 / 2
P46063 ATP-dependent DNA helicase Q1 Enzyme C00001408 C00001424 0 / 0
P18089 Alpha-2B adrenergic receptor Adrenergic receptor C00001408 C00001424 0 / 0
P35368 Alpha-1B adrenergic receptor Adrenergic receptor C00001408 C00001424 0 / 0
P23975 Sodium-dependent noradrenaline transporter Norepinephrine C00001408 C00001424 1 / 1
Q16236 Nuclear factor erythroid 2-related factor 2 Unclassified protein C00001424 C00002724 0 / 0
O15245 Solute carrier family 22 member 1 Drug uniporter C00001408 C00037562 0 / 0
O75164 Lysine-specific demethylase 4A Enzyme C00001424 C00002724 0 / 0
P02545 Prelamin-A/C Unclassified protein C00001424 C00005373 11 / 10
Q9UNA4 DNA polymerase iota Enzyme C00001408 C00005373 0 / 0
Q13951 Core-binding factor subunit beta Unclassified protein C00001424 C00005373 0 / 1
P10253 Lysosomal alpha-glucosidase Hydrolase C00005373 C00005413 1 / 1
P47989 Xanthine dehydrogenase/oxidase Oxidoreductase C00005373 C00005413 1 / 1
P35372 Mu-type opioid receptor Opioid receptor C00001424 C00005373 0 / 0
P08588 Beta-1 adrenergic receptor Adrenergic receptor C00001408 C00001424 1 / 0
P03372 Estrogen receptor NR3A1 C00003672 C00005413 1 / 1
Q9UNQ0 ATP-binding cassette sub-family G member 2 ATP binding cassette C00005373 C00005413 2 / 0
Q01196 Runt-related transcription factor 1 Unclassified protein C00001424 C00005373 1 / 4
O15244 Solute carrier family 22 member 2 Drug uniporter C00001408 C00001424 0 / 0
O94782 Ubiquitin carboxyl-terminal hydrolase 1 Enzyme C00001424 C00005413 0 / 0
P50224 Sulfotransferase 1A3/1A4 Enzyme C00001408 C00001424 0 / 0
P15121 Aldose reductase Enzyme C00002724 C00005373 0 / 0
P35348 Alpha-1A adrenergic receptor Adrenergic receptor C00001408 C00001424 0 / 0
P25100 Alpha-1D adrenergic receptor Adrenergic receptor C00001408 C00001424 0 / 0
O75496 Geminin Unclassified protein C00002724 C00005373 0 / 0
P21728 D(1A) dopamine receptor Dopamine receptor C00001408 C00001424 0 / 0
P00352 Retinal dehydrogenase 1 Enzyme C00001408 C00002724 0 / 0
P14416 D(2) dopamine receptor Dopamine receptor C00001408 C00001424 2 / 0
P07550 Beta-2 adrenergic receptor Adrenergic receptor C00001408 C00001424 0 / 1
Q9HAW7 UDP-glucuronosyltransferase 1-7 Enzyme C00001408 0 / 0
P11388 DNA topoisomerase 2-alpha Isomerase C00005413 0 / 0
P11473 Vitamin D3 receptor NR1I1 C00001424 2 / 3
P54132 Bloom syndrome protein Enzyme C00001424 1 / 2
P41145 Kappa-type opioid receptor Opioid receptor C00005373 0 / 0
P23280 Carbonic anhydrase 6 Lyase C00001408 0 / 0
O15296 Arachidonate 15-lipoxygenase B Enzyme C00001424 0 / 0
Q9ULX7 Carbonic anhydrase 14 Lyase C00001408 0 / 0
P14920 D-amino-acid oxidase Enzyme C00001424 0 / 0
O43570 Carbonic anhydrase 12 Lyase C00001408 1 / 2
P36888 Receptor-type tyrosine-protein kinase FLT3 Pdgfr C00005373 1 / 1
Q16665 Hypoxia-inducible factor 1-alpha Transcription Factor C00001408 0 / 0
P07237 Protein disulfide-isomerase Enzyme C00005373 0 / 0
Q92830 Histone acetyltransferase KAT2A Enzyme C00001424 0 / 0
P16662 UDP-glucuronosyltransferase 2B7 Enzyme C00001408 0 / 0
P50225 Sulfotransferase 1A1 Enzyme C00001408 0 / 0
O60656 UDP-glucuronosyltransferase 1-9 Enzyme C00002724 0 / 0
P54855 UDP-glucuronosyltransferase 2B15 Enzyme C00001408 0 / 0
Q99700 Ataxin-2 Unclassified protein C00001408 1 / 1
P21917 D(4) dopamine receptor Dopamine receptor C00001408 0 / 0
O95622 Adenylate cyclase type 5 Enzyme C00001408 1 / 0
P35462 D(3) dopamine receptor Dopamine receptor C00001408 1 / 0
P41143 Delta-type opioid receptor Opioid receptor C00005373 0 / 0
P06241 Tyrosine-protein kinase Fyn Src C00001408 0 / 0
P10145 Interleukin-8 Secreted protein C00002724 0 / 0
P00915 Carbonic anhydrase 1 Lyase C00001408 0 / 0
P49841 Glycogen synthase kinase-3 beta Gsk C00003672 0 / 0
P27487 Dipeptidyl peptidase 4 S9B C00005413 0 / 1
P40763 Signal transducer and activator of transcription 3 Transcription Factor C00002724 1 / 2
P43220 Glucagon-like peptide 1 receptor Glucagon-like peptide receptor C00001424 0 / 0
Q9GZT4 Serine racemase Enzyme C00001424 0 / 0
Q9Y253 DNA polymerase eta Enzyme C00005373 1 / 1
P09923 Intestinal-type alkaline phosphatase Enzyme C00005373 0 / 0
P05186 Alkaline phosphatase, tissue-nonspecific isozyme Enzyme C00005373 3 / 1
P83916 Chromobox protein homolog 1 Unclassified protein C00001424 0 / 0
P08183 Multidrug resistance protein 1 drug C00003672 1 / 0
P13945 Beta-3 adrenergic receptor Adrenergic receptor C00001424 0 / 0
P00734 Prothrombin S1A C00003672 4 / 2
P04150 Glucocorticoid receptor NR3C1 C00002724 0 / 1
Q9HAW8 UDP-glucuronosyltransferase 1-10 Enzyme C00001408 0 / 0
P31645 Sodium-dependent serotonin transporter Serotonin C00001408 2 / 0
P12931 Proto-oncogene tyrosine-protein kinase Src Src C00002724 0 / 0
P06276 Cholinesterase Hydrolase C00005413 0 / 0
P06280 Alpha-galactosidase A Enzyme C00005373 1 / 1
P48039 Melatonin receptor type 1A Melatonin receptor C00001408 0 / 0
P21918 D(1B) dopamine receptor Dopamine receptor C00001408 1 / 0
P10696 Alkaline phosphatase, placental-like Enzyme C00005373 0 / 1
Q9UIF8 Bromodomain adjacent to zinc finger domain protein 2B Unclassified protein C00005373 0 / 0
Q16790 Carbonic anhydrase 9 Lyase C00001408 0 / 1
Q16853 Membrane primary amine oxidase Enzyme C00001408 0 / 0
P49798 Regulator of G-protein signaling 4 Unclassified protein C00003672 2 / 0
Q01959 Sodium-dependent dopamine transporter Dopamine C00001408 1 / 0
P51692 Signal transducer and activator of transcription 5B Unclassified protein C00002724 1 / 1
P15428 15-hydroxyprostaglandin dehydrogenase [NAD(+)] Enzyme C00001424 2 / 2
Q96QE3 ATPase family AAA domain-containing protein 5 Unclassified protein C00001424 0 / 0
O60218 Aldo-keto reductase family 1 member B10 Enzyme C00002724 0 / 0
P00918 Carbonic anhydrase 2 Lyase C00001408 1 / 2
P22303 Acetylcholinesterase Hydrolase C00005413 1 / 0
P10828 Thyroid hormone receptor beta NR1A2 C00001424 3 / 1
P19838 Nuclear factor NF-kappa-B p105 subunit Transcription Factor C00037562 0 / 0
P16050 Arachidonate 15-lipoxygenase Enzyme C00001408 0 / 0
Q16637 Survival motor neuron protein Unclassified protein C00005373 4 / 1
P08047 Transcription factor Sp1 Unclassified protein C00003672 0 / 0
O43704 Sulfotransferase family cytosolic 1B member 1 Enzyme C00001408 0 / 0
Q99489 D-aspartate oxidase Enzyme C00001424 0 / 0
P04637 Cellular tumor antigen p53 Transcription Factor C00001408 7 / 37
P22309 UDP-glucuronosyltransferase 1-1 Enzyme C00001408 5 / 1
P18031 Tyrosine-protein phosphatase non-receptor type 1 Tyr C00003672 0 / 0
Q99549 M-phase phosphoprotein 8 Unclassified protein C00001408 0 / 0
P19224 UDP-glucuronosyltransferase 1-6 Enzyme C00002724 0 / 0
Q13526 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 Enzyme C00001424 0 / 0
P08908 5-hydroxytryptamine receptor 1A Serotonin receptor C00005373 1 / 0
P49286 Melatonin receptor type 1B Melatonin receptor C00001408 0 / 1
P43166 Carbonic anhydrase 7 Lyase C00001408 0 / 0
P35218 Carbonic anhydrase 5A, mitochondrial Lyase C00001408 0 / 0
P07451 Carbonic anhydrase 3 Lyase C00001408 0 / 0
P06239 Tyrosine-protein kinase Lck Src C00002724 0 / 1
P34949 Mannose-6-phosphate isomerase Enzyme C00005373 1 / 1
P48147 Prolyl endopeptidase S9A C00005413 0 / 0
P22748 Carbonic anhydrase 4 Lyase C00001408 1 / 1
P80365 Corticosteroid 11-beta-dehydrogenase isozyme 2 Enzyme C00003672 1 / 1
P22310 UDP-glucuronosyltransferase 1-4 Enzyme C00001408 3 / 0
P33527 Multidrug resistance-associated protein 1 drugs C00005413 0 / 0
Q9Y2D0 Carbonic anhydrase 5B, mitochondrial Lyase C00001408 0 / 0
P40225 Thrombopoietin Unclassified protein C00001408 1 / 1
P42224 Signal transducer and activator of transcription 1-alpha/beta Unclassified protein C00002724 3 / 3
Q9Y2I1 Nischarin Other cytosolic protein C00001424 0 / 0
P42345 Serine/threonine-protein kinase mTOR Enzyme C00001408 0 / 0
O00255 Menin Unclassified protein C00001424 2 / 5
Q03164 Histone-lysine N-methyltransferase 2A Enzyme C00001424 1 / 2
P04062 Glucosylceramidase Enzyme C00005373 6 / 4
Q13093 Platelet-activating factor acetylhydrolase Enzyme C00002724 3 / 0
O75751 Solute carrier family 22 member 3 Unclassified protein C00001424 0 / 0
Q12809 Potassium voltage-gated channel subfamily H member 2 KCNH, Kv10-12.x (Ether-a-go-go) C00002724 2 / 2
Q9NPH5 NADPH oxidase 4 Enzyme C00005373 0 / 0

128 Gene in CTD interactions

gene gene name gene description KNApSAcK metabolite in interactions
6818 SULT1A3, HAST, HAST3, M-PST, ST1A3/ST1A4, ST1A5, STM, TL-PST sulfotransferase family, cytosolic, 1A, phenol-preferring, member 3 (EC:2.8.2.1) C00001408 C00001424 C00037562
836 CASP3, CPP32, CPP32B, SCA-1 caspase 3, apoptosis-related cysteine peptidase (EC:3.4.22.56) C00001408 C00001424 C00005413
5594 MAPK1, ERK, ERK2, ERT1, MAPK2, P42MAPK, PRKM1, PRKM2, p38, p40, p41, p41mapk mitogen-activated protein kinase 1 (EC:2.7.11.24) C00001408 C00001424 C00005413
5595 MAPK3, ERK-1, ERK1, ERT2, HS44KDAP, HUMKER1A, P44ERK1, P44MAPK, PRKM3, p44-ERK1, p44-MAPK mitogen-activated protein kinase 3 (EC:2.7.11.24) C00001408 C00001424 C00005413
6570 SLC18A1, CGAT, VAT1, VMAT1 solute carrier family 18 (vesicular monoamine transporter), member 1 C00001408 C00001424
134864 TAAR1, RP11-295F4.9, TA1, TAR1, TRAR1 trace amine associated receptor 1 C00001408 C00001424
581 BAX, BCL2L4 BCL2-associated X protein C00001408 C00005413
6532 SLC6A4, 5-HTT, 5-HTTLPR, 5HTT, HTT, OCD1, SERT, SERT1, hSERT solute carrier family 6 (neurotransmitter transporter), member 4 C00001408 C00001424
6531 SLC6A3, DAT, DAT1, PKDYS solute carrier family 6 (neurotransmitter transporter), member 3 C00001408 C00001424
6530 SLC6A2, NAT1, NET, NET1, SLC6A5 solute carrier family 6 (neurotransmitter transporter), member 2 C00001408 C00001424
6571 SLC18A2, SVAT, SVMT, VAT2, VMAT2 solute carrier family 18 (vesicular monoamine transporter), member 2 C00001408 C00001424
7124 TNF, DIF, TNF-alpha, TNFA, TNFSF2 tumor necrosis factor C00001408 C00005413
3569 IL6, BSF2, HGF, HSF, IFNB2, IL-6 interleukin 6 (interferon, beta 2) C00001424 C00005413
3576 IL8, CXCL8, GCP-1, GCP1, LECT, LUCT, LYNAP, MDNCF, MONAP, NAF, NAP-1, NAP1 interleukin 8 C00001424 C00005413
3725 JUN, AP-1, AP1, c-Jun jun proto-oncogene C00001408 C00005413
1813 DRD2, D2DR, D2R dopamine receptor D2 C00001408 C00001424
1543 CYP1A1, AHH, AHRR, CP11, CYP1, P1-450, P450-C, P450DX cytochrome P450, family 1, subfamily A, polypeptide 1 (EC:1.14.14.1) C00001408 C00005413
1312 COMT catechol-O-methyltransferase (EC:2.1.1.6) C00001408 C00001424
847 CAT catalase (EC:1.11.1.6) C00001408 C00005413
840 CASP7, CASP-7, CMH-1, ICE-LAP3, LICE2, MCH3 caspase 7, apoptosis-related cysteine peptidase (EC:3.4.22.60) C00001408 C00001424
5970 RELA, NFKB3, p65 v-rel avian reticuloendotheliosis viral oncogene homolog A C00001424 C00005413
596 BCL2, Bcl-2, PPP1R50 B-cell CLL/lymphoma 2 C00001408 C00005413
155 ADRB3, BETA3AR adrenoceptor beta 3 C00001424
5468 PPARG, CIMT1, GLM1, NR1C3, PPARG1, PPARG2, PPARgamma peroxisome proliferator-activated receptor gamma C00002724
5886 RAD23A, HHR23A, HR23A RAD23 homolog A (S. cerevisiae) C00002724
5914 RARA, NR1B1, RAR retinoic acid receptor, alpha C00002724
6256 RXRA, NR2B1 retinoid X receptor, alpha C00002724
6649 SOD3, EC-SOD superoxide dismutase 3, extracellular (EC:1.15.1.1) C00002724
6716 SRD5A2 steroid-5-alpha-reductase, alpha polypeptide 2 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 2) (EC:1.3.1.22) C00002724
7178 TPT1, HRF, TCTP, p02, p23 tumor protein, translationally-controlled 1 C00002724
7295 TXN, TRDX, TRX, TRX1 thioredoxin C00002724
7299 TYR, ATN, CMM8, OCA1, OCA1A, OCAIA, SHEP3 tyrosinase (EC:1.14.18.1) C00002724
7306 TYRP1, CAS2, CATB, GP75, OCA3, TRP, TRP1, TYRP, b-PROTEIN tyrosinase-related protein 1 (EC:1.14.18.-) C00002724
54575 UGT1A10, UDPGT, UGT-1J, UGT1-10, UGT1.10, UGT1J UDP glucuronosyltransferase 1 family, polypeptide A10 (EC:2.4.1.17) C00002724
54659 UGT1A3, UDPGT, UDPGT_1-3, UGT-1C, UGT1-03, UGT1.3, UGT1C UDP glucuronosyltransferase 1 family, polypeptide A3 (EC:2.4.1.17) C00002724
54577 UGT1A7, UDPGT, UDPGT_1-7, UGT-1G, UGT1-07, UGT1.7, UGT1G UDP glucuronosyltransferase 1 family, polypeptide A7 (EC:2.4.1.17) C00002724
54576 UGT1A8, UDPGT, UDPGT_1-8, UGT-1H, UGT1-08, UGT1.8, UGT1A8S, UGT1H UDP glucuronosyltransferase 1 family, polypeptide A8 (EC:2.4.1.17) C00002724
183 AGT, ANHU, SERPINA8 angiotensinogen (serpin peptidase inhibitor, clade A, member 8) C00001408
47 ACLY, ACL, ATPCL, CLATP ATP citrate lyase (EC:2.3.3.8) C00002724
27113 BBC3, JFY-1, JFY1, PUMA BCL2 binding component 3 C00001408
5241 PGR, NR3C3, PR progesterone receptor C00002724
664 BNIP3, NIP3 BCL2/adenovirus E1B 19kDa interacting protein 3 C00001408
4846 NOS3, ECNOS, eNOS nitric oxide synthase 3 (endothelial cell) (EC:1.14.13.39) C00002724
4157 MC1R, CMM5, MSH-R, SHEP2 melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor) C00002724
3852 KRT5, CK5, DDD, DDD1, EBS2, K5, KRT5A keratin 5 C00002724
3552 IL1A, IL-1A, IL1, IL1-ALPHA, IL1F1 interleukin 1, alpha C00002724
3315 HSPB1, CMT2F, HMN2B, HS.76067, HSP27, HSP28, Hsp25, SRP27 heat shock 27kDa protein 1 C00002724
1565 CYP2D6, CPD6, CYP2D, CYP2D7AP, CYP2D7BP, CYP2D7P2, CYP2D8P2, CYP2DL1, CYPIID6, P450-DB1, P450C2D, P450DB1 cytochrome P450, family 2, subfamily D, polypeptide 6 (EC:1.14.14.1) C00001408
1576 CYP3A4, CP33, CP34, CYP3A, CYP3A3, CYPIIIA3, CYPIIIA4, HLP, NF-25, P450C3, P450PCN1 cytochrome P450, family 3, subfamily A, polypeptide 4 (EC:1.14.13.67 1.14.13.97 1.14.13.32 1.14.13.157) C00001408
1812 DRD1, DADR, DRD1A dopamine receptor D1 C00001408
3036 HAS1, HAS hyaluronan synthase 1 (EC:2.4.1.212) C00002724
2152 F3, CD142, TF, TFA coagulation factor III (thromboplastin, tissue factor) C00001408
2353 FOS, AP-1, C-FOS, p55 FBJ murine osteosarcoma viral oncogene homolog C00001408
2668 GDNF, ATF1, ATF2, HFB1-GDNF, HSCR3 glial cell derived neurotrophic factor C00001408
2938 GSTA1, GST2, GSTA1-1, GTH1 glutathione S-transferase alpha 1 (EC:2.5.1.18) C00001408
2944 GSTM1, GST1, GSTM1-1, GSTM1a-1a, GSTM1b-1b, GTH4, GTM1, H-B, MU, MU-1 glutathione S-transferase mu 1 (EC:2.5.1.18) C00001408
2950 GSTP1, DFN7, FAEES3, GST3, GSTP, PI glutathione S-transferase pi 1 (EC:2.5.1.18) C00001408
3091 HIF1A, HIF-1A, HIF-1alpha, HIF1, HIF1-ALPHA, MOP1, PASD8, bHLHe78 hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) C00001408
3162 HMOX1, HMOX1D, HO-1, HSP32, bK286B10 heme oxygenase (decycling) 1 (EC:1.14.99.3) C00001408
3359 HTR3A, 5-HT-3, 5-HT3A, 5-HT3R, 5HT3R, HTR3 5-hydroxytryptamine (serotonin) receptor 3A, ionotropic C00001408
9177 HTR3B, 5-HT3B 5-hydroxytryptamine (serotonin) receptor 3B, ionotropic C00001408
3630 INS, IDDM2, ILPR, IRDN, MODY10 insulin C00001408
2896 GRN, CLN11, GEP, GP88, PCDGF, PEPI, PGRN granulin C00002724
2246 FGF1, AFGF, ECGF, ECGF-beta, ECGFA, ECGFB, FGF-1, FGF-alpha, FGFA, GLIO703, HBGF-1, HBGF1 fibroblast growth factor 1 (acidic) C00002724
2201 FBN2, CCA, DA9 fibrillin 2 C00002724
4137 MAPT, DDPAC, FTDP-17, MAPTL, MSTD, MTBT1, MTBT2, PPND, TAU microtubule-associated protein tau C00001408
2475 MTOR, FRAP, FRAP1, FRAP2, RAFT1, RAPT1 mechanistic target of rapamycin (serine/threonine kinase) (EC:2.7.11.1) C00001408
4548 MTR, HMAG, MS, cblG 5-methyltetrahydrofolate-homocysteine methyltransferase (EC:2.1.1.13) C00001408
5071 PARK2, AR-JP, LPRS2, PDJ, PRKN parkin RBR E3 ubiquitin protein ligase C00001408
142 PARP1, ADPRT, ADPRT_1, ADPRT1, ARTD1, PARP, PARP-1, PPOL, pADPRT-1 poly (ADP-ribose) polymerase 1 (EC:2.4.2.30) C00001408
5617 PRL prolactin C00001408
5998 RGS3, C2PA, RGP3 regulator of G-protein signaling 3 C00001408
6198 RPS6KB1, PS6K, S6K, S6K-beta-1, S6K1, STK14A, p70_S6KA, p70(S6K)-alpha, p70-S6K, p70-alpha ribosomal protein S6 kinase, 70kDa, polypeptide 1 (EC:2.7.11.1) C00001408
6343 SCT secretin C00001408
2200 FBN1, ACMICD, ECTOL1, FBN, GPHYSD2, MASS, MFS1, OCTD, SGS, SSKS, WMS, WMS2 fibrillin 1 C00002724
1950 EGF, HOMG4, URG epidermal growth factor C00002724
85413 SLC22A16, CT2, FLIPT2, OAT6, OCT6, OKB1, dJ261K5.1 solute carrier family 22 (organic cation/carnitine transporter), member 16 C00001408
9016 SLC25A14, BMCP1, UCP5 solute carrier family 25 (mitochondrial carrier, brain), member 14 C00001408
1830 DSG3, CDHF6, PVA desmoglein 3 C00002724
114757 CYGB, HGB, STAP cytoglobin C00002724
4512 COX1, COI, MTCO1, MT-CO1 cytochrome c oxidase subunit I C00002724
6622 SNCA, NACP, PARK1, PARK4, PD1 synuclein, alpha (non A4 component of amyloid precursor) C00001408
6817 SULT1A1, HAST1/HAST2, P-PST, PST, ST1A1, ST1A3, STP, STP1, TSPST1 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1 (EC:2.8.2.1) C00001408
1277 COL1A1, OI4 collagen, type I, alpha 1 C00002724
999 CDH1, Arc-1, CD324, CDHE, ECAD, LCAM, UVO cadherin 1, type 1, E-cadherin (epithelial) C00002724
7054 TH, DYT14, DYT5b, TYH tyrosine hydroxylase (EC:1.14.16.2) C00001408
960 CD44, CDW44, CSPG8, ECMR-III, HCELL, HUTCH-I, IN, LHR, MC56, MDU2, MDU3, MIC4, Pgp1 CD44 molecule (Indian blood group) C00002724
7157 TP53, BCC7, LFS1, P53, TRP53 tumor protein p53 C00001408
148 ADRA1A, ADRA1C, ADRA1L1, ALPHA1AAR adrenoceptor alpha 1A C00001424
147 ADRA1B, ADRA1, ALPHA1BAR adrenoceptor alpha 1B C00001424
146 ADRA1D, ADRA1, ADRA1A, ADRA1R, ALPHA1, DAR, dJ779E11.2 adrenoceptor alpha 1D C00001424
150 ADRA2A, ADRA2, ADRA2R, ADRAR, ALPHA2AAR, ZNF32 adrenoceptor alpha 2A C00001424
151 ADRA2B, ADRA2L1, ADRA2RL1, ADRARL1, ALPHA2BAR, alpha-2BAR adrenoceptor alpha 2B C00001424
152 ADRA2C, ADRA2L2, ADRA2RL2, ADRARL2, ALPHA2CAR adrenoceptor alpha 2C C00001424
153 ADRB1, ADRB1R, B1AR, BETA1AR, RHR adrenoceptor beta 1 C00001424
154 ADRB2, ADRB2R, ADRBR, B2AR, BAR, BETA2AR adrenoceptor beta 2, surface C00001424
8985 PLOD3, LH3 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3 (EC:1.14.11.4) C00002724
6352 CCL5, D17S136E, RANTES, SCYA5, SIS-delta, SISd, TCP228, eoCP chemokine (C-C motif) ligand 5 C00001424
2335 FN1, CIG, ED-B, FINC, FN, FNZ, GFND, GFND2, LETS, MSF fibronectin 1 C00001424
2778 GNAS, AHO, C20orf45, GNAS1, GPSA, GSA, GSP, NESP, PHP1A, PHP1B, PHP1C, POH GNAS complex locus C00001424
367 AR, AIS, DHTR, HUMARA, HYSP1, KD, NR3C4, SBMA, SMAX1, TFM androgen receptor C00002724
360 AQP3, AQP-3, GIL aquaporin 3 (Gill blood group) C00002724
4128 MAOA, MAO-A monoamine oxidase A (EC:1.4.3.4) C00001424
4790 NFKB1, EBP-1, KBF1, NF-kB1, NF-kappa-B, NF-kappaB, NFKB-p105, NFKB-p50, NFkappaB, p105, p50 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 C00001424
4879 NPPB, BNP natriuretic peptide B C00001424
4852 NPY, PYY4 neuropeptide Y C00001424
358 AQP1, AQP-CHIP, CHIP28, CO aquaporin 1 C00002724
6279 S100A8, 60B8AG, CAGA, CFAG, CGLA, CP-10, L1Ag, MA387, MIF, MRP8, NIF, P8 S100 calcium binding protein A8 C00001424
6280 S100A9, 60B8AG, CAGB, CFAG, CGLB, L1AG, LIAG, MAC387, MIF, MRP14, NIF, P14 S100 calcium binding protein A9 C00001424
6285 S100B, NEF, S100, S100-B, S100beta S100 calcium binding protein B C00001424
7391 USF1, FCHL, FCHL1, HYPLIP1, MLTF, MLTFI, UEF, bHLHb11 upstream transcription factor 1 C00001424
177 AGER, RAGE advanced glycosylation end product-specific receptor C00005413
196 AHR, bHLHe76 aryl hydrocarbon receptor C00005413
405 ARNT, HIF-1-beta, HIF-1beta, HIF1-beta, HIF1B, HIF1BETA, TANGO, bHLHe2 aryl hydrocarbon receptor nuclear translocator C00005413
873 CBR1, CBR, SDR21C1, hCBR1 carbonyl reductase 1 (EC:1.1.1.189 1.1.1.197 1.1.1.184) C00005413
6347 CCL2, GDCF-2, HC11, HSMCR30, MCAF, MCP-1, MCP1, SCYA2, SMC-CF chemokine (C-C motif) ligand 2 C00005413
3627 CXCL10, C7, IFI10, INP10, IP-10, SCYB10, crg-2, gIP-10, mob-1 chemokine (C-X-C motif) ligand 10 C00005413
1545 CYP1B1, CP1B, CYPIB1, GLC3A, P4501B1 cytochrome P450, family 1, subfamily B, polypeptide 1 (EC:1.14.14.1) C00005413
1956 EGFR, ERBB, ERBB1, HER1, PIG61, mENA epidermal growth factor receptor (EC:2.7.10.1) C00005413
2936 GSR glutathione reductase (EC:1.8.1.7) C00005413
3458 IFNG, IFG, IFI interferon, gamma C00005413
3480 IGF1R, CD221, IGFIR, IGFR, JTK13 insulin-like growth factor 1 receptor (EC:2.7.10.1) C00005413
3553 IL1B, IL-1, IL1-BETA, IL1F2 interleukin 1, beta C00005413
3667 IRS1, HIRS-1 insulin receptor substrate 1 C00005413
4792 NFKBIA, IKBA, MAD-3, NFKBI nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha C00005413
5743 PTGS2, COX-2, COX2, GRIPGHS, PGG/HS, PGHS-2, PHS-2, hCox-2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) (EC:1.14.99.1) C00005413
7039 TGFA, TFGA transforming growth factor, alpha C00005413
7422 VEGFA, MVCD1, VEGF, VPF vascular endothelial growth factor A C00005413

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (109)

OMIM preferred title UniProt
#300438 17-beta-hydroxysteroid dehydrogenase x deficiency Q99714
#202300 Adrenocortical carcinoma, hereditary; adcc P04637
#103470 Albinism, ocular, with sensorineural deafness P14679
#203100 Albinism, oculocutaneous, type ia; oca1a P14679
#606952 Albinism, oculocutaneous, type ib; oca1b P14679
#103780 Alcohol dependence P14416
P31645
#218030 Apparent mineralocorticoid excess; ame P80365
#600807 Asthma, susceptibility to Q13093
#209950 Atypical mycobacteriosis, familial P42224
#614740 Basal cell carcinoma, susceptibility to, 7; bcc7 P04637
#601816 Bilirubin, serum level of, quantitative trait locus 1; biliqtl1 P22309
#606798 Blepharospasm, benign essential P21918
#614490 Blood group, junior system; jr Q9UNQ0
#210900 Bloom syndrome; blm P54132
#614162 Candidiasis, familial, 7; candf7 P42224
#115200 Cardiomyopathy, dilated, 1a; cmd1a P02545
#212112 Cardiomyopathy, dilated, with hypergonadotropic hypogonadism P02545
#605588 Charcot-marie-tooth disease, axonal, type 2b1; cmt2b1 P02545
#602579 Congenital disorder of glycosylation, type ib; cdg1b P34949
#218800 Crigler-najjar syndrome, type i P22309
P22310
#606785 Crigler-najjar syndrome, type ii P22309
P22310
#119900 Digital clubbing, isolated congenital P15428
#609535 Drug metabolism, poor, cyp2c19-related P33261
#608902 Drug metabolism, poor, cyp2d6-related P10635
#606703 Dyskinesia, familial, with facial myokymia; fdfm O95622
#181350 Emery-dreifuss muscular dystrophy 2, autosomal dominant; edmd2 P02545
#133239 Esophageal cancer P04637
#615363 Estrogen resistance; estrr P03372
#301500 Fabry disease P06280
#600274 Frontotemporal dementia; ftd P10636
#608013 Gaucher disease, perinatal lethal P04062
#230800 Gaucher disease, type i P04062
#230900 Gaucher disease, type ii P04062
#231000 Gaucher disease, type iii P04062
#231005 Gaucher disease, type iiic P04062
#143500 Gilbert syndrome P22309
P22310
#232300 Glycogen storage disease ii P10253
#245590 Growth hormone insensitivity with immunodeficiency P51692
#605130 Hairy elbows, short stature, facial dysmorphism, and developmental delay Q03164
#610140 Heart-hand syndrome, slovenian type P02545
#176670 Hutchinson-gilford progeria syndrome; hgps P02545
#147060 Hyper-ige recurrent infection syndrome, autosomal dominant P40763
#237900 Hyperbilirubinemia, transient familial neonatal; hblrtfn P22309
#143860 Hyperchlorhidrosis, isolated O43570
#145000 Hyperparathyroidism 1; hrpt1 O00255
#603373 Hyperthyroidism, familial gestational P16473
#609152 Hyperthyroidism, nonautoimmune P16473
#259100 Hypertrophic osteoarthropathy, primary, autosomal recessive, 1; phoar1 P15428
#146300 Hypophosphatasia, adult P05186
#241510 Hypophosphatasia, childhood P05186
#241500 Hypophosphatasia, infantile P05186
#275200 Hypothyroidism, congenital, nongoitrous, 1; chng1 P16473
#147050 Ige responsiveness, atopic; iger Q13093
#612244 Inflammatory bowel disease 13; ibd13 P08183
#601626 Leukemia, acute myeloid; aml P36888
#151623 Li-fraumeni syndrome 1; lfs1 P04637
#151660 Lipodystrophy, familial partial, type 2; fpld2 P02545
#613688 Long qt syndrome 2; lqt2 Q12809
#211980 Lung cancer P04637
#248370 Mandibuloacral dysplasia with type a lipodystrophy; mada P02545
#300705 Mental retardation, x-linked 17; mrx17 Q99714
#300220 Mental retardation, x-linked, syndromic 10; mrxs10 Q99714
#131100 Multiple endocrine neoplasia, type i; men1 O00255
#613205 Muscular dystrophy, congenital, lmna-related P02545
#159001 Muscular dystrophy, limb-girdle, type 1b; lgmd1b P02545
#613796 Mycobacterial and viral infections, susceptibility to, autosomal recessive P42224
#607948 Mycobacterium tuberculosis, susceptibility to P11473
#159900 Myoclonic dystonia P14416
#160900 Myotonic dystrophy 1; dm1 Q9NR56
#164230 Obsessive-compulsive disorder; ocd P31645
#604715 Orthostatic intolerance P23975
#259730 Osteopetrosis, autosomal recessive 3; optb3 P00918
#260500 Papilloma of choroid plexus; cpp P04637
#168600 Parkinson disease, late-onset; pd P04062
#260540 Parkinson-dementia syndrome P10636
#613135 Parkinsonism-dystonia, infantile; pkdys Q01959
#614674 Periodic fever, menstrual cycle-dependent P08908
#172700 Pick disease of brain P10636
#601399 Platelet disorder, familial, with associated myeloid malignancy Q01196
#614278 Platelet-activating factor acetylhydrolase deficiency; pafad Q13093
#614390 Pregnancy loss, recurrent, susceptibility to, 2; rprgl2 P00734
#613679 Prothrombin deficiency, congenital P00734
#607276 Resting heart rate, variation in P08588
#275210 Restrictive dermopathy, lethal P02545
#600852 Retinitis pigmentosa 17; rp17 P22748
#604906 Schizophrenia 9; sczd9 P49798
#181500 Schizophrenia; sczd P49798
#609620 Short qt syndrome 1; sqt1 Q12809
#601800 Skin/hair/eye pigmentation, variation in, 3; shep3 P14679
#253300 Spinal muscular atrophy, type i; sma1 Q16637
#253550 Spinal muscular atrophy, type ii; sma2 Q16637
#253400 Spinal muscular atrophy, type iii; sma3 Q16637
#271150 Spinal muscular atrophy, type iv; sma4 Q16637
#183090 Spinocerebellar ataxia 2; sca2 Q99700
#607250 Spinocerebellar ataxia, autosomal recessive, with axonal neuropathy; scan1 Q9NUW8
#275355 Squamous cell carcinoma, head and neck; hnscc P04637
#601367 Stroke, ischemic P00734
#601104 Supranuclear palsy, progressive, 1; psnp1 P10636
#187950 Thrombocythemia 1; thcyt1 P40225
#188050 Thrombophilia due to thrombin defect; thph1 P00734
#188570 Thyroid hormone resistance, generalized, autosomal dominant; grth P10828
#274300 Thyroid hormone resistance, generalized, autosomal recessive; grth P10828
#145650 Thyroid hormone resistance, selective pituitary; prth P10828
#190300 Tremor, hereditary essential, 1; etm1 P35462
#138900 Uric acid concentration, serum, quantitative trait locus 1; uaqtl1 Q9UNQ0
#277440 Vitamin d-dependent rickets, type 2a; vddr2a P11473
#278300 Xanthinuria, type i P47989
#278750 Xeroderma pigmentosum, variant type; xpv Q9Y253
#112100 Yt blood group antigen P22303

KEGG DISEASE (108)

KEGG name UniProt
H00033 Adrenal carcinoma O00255 (related)
P04637 (related)
H00034 Carcinoid O00255 (related)
H00045 Malignant islet cell carcinoma O00255 (related)
H00246 Primary hyperparathyroidism O00255 (related)
H01102 Pituitary adenomas O00255 (related)
H01302 Hyperchlorhidrosis isolated (HCHLH) O43570 (related)
H00021 Renal cell carcinoma O43570 (marker)
P04637 (marker)
Q16790 (marker)
H00223 Inherited thrombophilia P00734 (related)
H01254 Congenital prothrombin deficiency P00734 (related)
H00241 Combined proximal and distal renal tubular acidosis (RTA type 3) P00918 (related)
H00436 Osteopetrosis P00918 (related)
H00264 Charcot-Marie-Tooth disease (CMT) P02545 (related)
H00294 Dilated cardiomyopathy (DCM) P02545 (related)
H00420 Familial partial lipodystrophy (FPL) P02545 (related)
H00563 Emery-Dreifuss muscular dystrophy P02545 (related)
H00590 Congenital muscular dystrophies (CMD/MDC) P02545 (related)
H00593 Limb-girdle muscular dystrophy (LGMD) P02545 (related)
H00601 Hutchinson-Gilford progeria syndrome P02545 (related)
H00663 Restrictive dermopathy P02545 (related)
H00665 Mandibuloacral dysplasia P02545 (related)
H01216 Left ventricular noncompaction (LVNC) P02545 (related)
H00026 Endometrial Cancer P03372 (marker)
P04637 (related)
H00066 Lewy body dementia (LBD) P04062 (related)
H00126 Gaucher disease P04062 (related)
H00426 Defects in the degradation of ganglioside P04062 (related)
H00810 Progressive myoclonic epilepsy (PME) P04062 (related)
H00599 46,XX disorders of sex development (Disorders related to androgen excess) P04150 (related)
H00004 Chronic myeloid leukemia (CML) P04637 (related)
Q01196 (related)
H00005 Chronic lymphocytic leukemia (CLL) P04637 (related)
H00006 Hairy-cell leukemia P04637 (related)
H00008 Burkitt lymphoma P04637 (related)
H00009 Adult T-cell leukemia P04637 (related)
H00010 Multiple myeloma P04637 (related)
H00013 Small cell lung cancer P04637 (related)
H00014 Non-small cell lung cancer P04637 (related)
H00015 Malignant pleural mesothelioma P04637 (related)
H00016 Oral cancer P04637 (related)
P04637 (marker)
P40763 (related)
H00017 Esophageal cancer P04637 (related)
P04637 (marker)
P35354 (related)
H00018 Gastric cancer P04637 (related)
H00019 Pancreatic cancer P04637 (related)
P04637 (marker)
H00020 Colorectal cancer P04637 (related)
P04637 (marker)
H00022 Bladder cancer P04637 (related)
H00025 Penile cancer P04637 (related)
P04637 (marker)
P35354 (related)
H00027 Ovarian cancer P04637 (related)
H00028 Choriocarcinoma P04637 (related)
H00029 Vulvar cancer P04637 (related)
H00031 Breast cancer P04637 (related)
H00032 Thyroid cancer P04637 (related)
P27487 (marker)
H00036 Osteosarcoma P04637 (related)
P08684 (marker)
H00038 Malignant melanoma P04637 (related)
P14679 (marker)
H00039 Basal cell carcinoma P04637 (related)
H00040 Squamous cell carcinoma P04637 (related)
H00041 Kaposi's sarcoma P04637 (related)
H00042 Glioma P04637 (related)
P04637 (marker)
H00044 Cancer of the anal canal P04637 (related)
H00046 Cholangiocarcinoma P04637 (related)
P35354 (related)
H00047 Gallbladder cancer P04637 (related)
H00048 Hepatocellular carcinoma P04637 (related)
H00055 Laryngeal cancer P04637 (related)
P04637 (marker)
H00881 Li-Fraumeni syndrome P04637 (related)
H01007 Choroid plexus papilloma P04637 (related)
H00213 Hypophosphatasia P05186 (related)
H00093 Combined immunodeficiencies (CIDs) P06239 (related)
H00125 Fabry disease P06280 (related)
H00079 Asthma P07550 (related)
H00069 Glycogen storage diseases (GSD) P10253 (related)
H00058 Amyotrophic lateral sclerosis (ALS) P10636 (related)
H00077 Progressive supranuclear palsy (PSP) P10636 (related)
H00078 Frontotemporal lobar degeneration (FTLD) P10636 (related)
H00023 Testicular cancer P10696 (marker)
H00249 Thyroid hormone resistance syndrome P10828 (related)
H00342 Tuberculosis P11473 (related)
H00784 Localized autosomal recessive hypotrichosis P11473 (related)
H01143 Vitamin D-dependent rickets P11473 (related)
H01205 Coumarin resistance P11712 (related)
H00168 Oculocutaneous albinism (OCA) P14679 (related)
H00457 Primary hypertrophic osteoarthropathy (PHO) P15428 (related)
H01246 Isolated congenital nail clubbing (ICNC) P15428 (related)
H00250 Congenital nongoitrous hypothyroidism (CHNG) P16473 (related)
H01269 Congenital hyperthyroidism P16473 (related)
H00208 Hyperbilirubinemia P22309 (related)
H00527 Retinitis pigmentosa (RP) P22748 (related)
H01031 Orthostatic intolerance (OI) P23975 (related)
H01171 Poor drug metabolism (PM) P33261 (related)
H00118 Congenital disorders of glycosylation (CDG) type I P34949 (related)
H00003 Acute myeloid leukemia (AML) P36888 (related)
Q01196 (related)
Q01196 (marker)
Q13951 (marker)
H00227 Congenital amegakaryocytic thrombocytopenia (CAMT) P40225 (marker)
H00107 Other well-defined immunodeficiency syndromes P40763 (related)
H00089 IFN-gamma/IL-12 axis P42224 (related)
H00363 Candidiasis P42224 (related)
H01109 Chronic mucocutaneous candidiasis (CMC) P42224 (related)
H00192 Xanthinuria P47989 (related)
H00409 Type II diabetes mellitus P49286 (related)
H00931 Growth hormone insensitivity with immunodeficiency P51692 (related)
H00094 DNA repair defects P54132 (related)
H00296 Defects in RecQ helicases P54132 (related)
H00259 Apparent mineralocorticoid excess syndrome P80365 (related)
H00001 Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) Q01196 (related)
Q01196 (marker)
Q03164 (related)
Q03164 (marker)
H00978 Thrombocytopenia (THC) Q01196 (related)
H00002 Acute lymphoblastic leukemia (ALL) (precursor T lymphoblastic leukemia) Q03164 (related)
H00720 Long QT syndrome Q12809 (related)
H00725 Short QT syndrome Q12809 (related)
H00455 Spinal muscular atrophy (SMA) Q16637 (related)
H00063 Spinocerebellar ataxia (SCA) Q99700 (related)
Q9NUW8 (related)
H00480 Non-syndromic X-linked mental retardation Q99714 (related)
H00658 Syndromic X-linked mental retardation Q99714 (related)
H00925 2-Methyl-3-hydroxybutyryl-CoA dehydrogenase (MHBD) deficiency Q99714 (related)
H00403 Disorders of nucleotide excision repair Q9Y253 (related)

Diseases related to CTD interactions

128 disease in interactions with metabolites

MESH or OMIM name KNApSAcK
metabolite
D006973 Hypertension C00001408
C00001424
C00037562
D004409 Dyskinesia, Drug-Induced C00001408
C00001424
C00005413
D009336 Necrosis C00002724
C00001408
C00001424
D012769 Shock C00001408
C00001424
D013616 Tachycardia, Sinus C00001408
C00001424
D013610 Tachycardia C00001408
C00001424
D013375 Substance Withdrawal Syndrome C00001408
C00001424
D007674 Kidney Diseases C00001424
C00005413
D013226 Status Epilepticus C00001408
C00001424
D058186 Acute Kidney Injury C00001408
C00001424
D012772 Shock, Septic C00001408
C00001424
D001145 Arrhythmias, Cardiac C00001408
C00001424
D012770 Shock, Cardiogenic C00001408
C00001424
D002303 Cardiac Output, Low C00001408
C00001424
D002375 Catalepsy C00001408
C00001424
D018487 Ventricular Dysfunction, Left C00001408
C00001424
D012640 Seizures C00001408
C00001424
D019970 Cocaine-Related Disorders C00001408
C00001424
D009846 Oliguria C00001408
C00001424
D009410 Nerve Degeneration C00001408
C00001424
D010243 Paralysis C00001424
C00005413
D017202 Myocardial Ischemia C00001408
C00001424
D007024 Hypotension, Orthostatic C00001408
C00001424
D006323 Heart Arrest C00001408
C00001424
D006331 Heart Diseases C00001408
C00001424
D006333 Heart Failure C00001408
C00001424
D007022 Hypotension C00001408
C00001424
D006930 Hyperalgesia C00001408
C00001424
D007008 Hypokalemia C00001408
C00001424
D000647 Amnesia C00002724
C00001424
D009798 Ocular Hypertension C00001424
D018476 Hypokinesia C00001408
D006556 Heroin Dependence C00001408
D004802 Eosinophilia C00001408
D007859 Learning Disorders C00001408
D008133 Long QT Syndrome C00001408
D020149 Manganese Poisoning C00001408
D048629 Micronuclei, Chromosome-Defective C00001408
D004417 Dyspnea C00001408
D009205 Myocarditis C00001408
D062787 Drug Overdose C00001408
D009422 Nervous System Diseases C00001408
D004342 Drug Hypersensitivity C00001408
D010300 Parkinson Disease C00001408
D020734 Parkinsonian Disorders C00001408
D010547 Persistent Fetal Circulation Syndrome C00001408
D011595 Psychomotor Agitation C00001408
D012127 Respiratory Distress Syndrome, Newborn C00001408
D002493 Central Nervous System Diseases C00001408
D002389 Catatonia C00001408
D001480 Basal Ganglia Diseases C00001408
D000788 Angina Pectoris, Variant C00001408
D015431 Weight Loss C00002724
D008545 Melanoma C00002724
D052456 Hypoalphalipoproteinemias C00002724
D015228 Hypertriglyceridemia C00002724
D016171 Torsades de Pointes C00001408
D014202 Tremor C00001408
D020301 Vasospasm, Intracranial C00001408
D006951 Hyperlipoproteinemias C00002724
D019969 Amphetamine-Related Disorders C00001424
D017542 Aneurysm, Ruptured C00001424
D000860 Anoxia C00001424
D001002 Anuria C00001424
D001008 Anxiety Disorders C00001424
D001237 Asphyxia C00001424
D001321 Autistic Disorder C00001424
D001766 Blindness C00001424
D001919 Bradycardia C00001424
D002545 Brain Ischemia C00001424
D002037 Bundle-Branch Block C00001424
D002100 Cachexia C00001424
D006332 Cardiomegaly C00001424
D009202 Cardiomyopathies C00001424
D002543 Cerebral Hemorrhage C00001424
D003922 Diabetes Mellitus, Type 1 C00001424
D004421 Dystonia C00001424
D004827 Epilepsy C00001424
D005901 Glaucoma C00001424
D005921 Glomerulonephritis C00001424
D005923 Glomerulosclerosis, Focal Segmental C00001424
D006261 Headache C00001424
D006470 Hemorrhage C00001424
D006935 Hypercapnia C00001424
D006940 Hyperemia C00001424
D006974 Hypertension, Malignant C00001424
D006976 Hypertension, Pulmonary C00001424
D006984 Hypertrophy C00001424
D017379 Hypertrophy, Left Ventricular C00001424
D007035 Hypothermia C00001424
D007511 Ischemia C00001424
D006937 Hypercholesterolemia C00002724
D008113 Liver Neoplasms C00001424
D008114 Liver Neoplasms, Experimental C00001424
D009203 Myocardial Infarction C00001424
D015428 Myocardial Reperfusion Injury C00001424
D006948 Hyperkinesis C00001408
D009901 Optic Nerve Diseases C00001424
D010146 Pain C00001424
D056486 Drug-Induced Liver Injury C00002724
D010554 Personality Disorders C00001424
D011183 Postoperative Complications C00001424
D011249 Pregnancy Complications, Cardiovascular C00001424
D011297 Prenatal Exposure Delayed Effects C00001424
D011507 Proteinuria C00001424
D011605 Psychoses, Substance-Induced C00001424
D029424 Pulmonary Disease, Chronic Obstructive C00001424
D051437 Renal Insufficiency C00001424
D012120 Respiration Disorders C00001424
D012131 Respiratory Insufficiency C00001424
D012164 Retinal Diseases C00001424
D012206 Rhabdomyolysis C00001424
D018805 Sepsis C00001424
D012771 Shock, Hemorrhagic C00001424
D013035 Spasm C00001424
D013274 Stomach Neoplasms C00001424
D013345 Subarachnoid Hemorrhage C00001424
D017180 Tachycardia, Ventricular C00001424
D014511 Uremia C00001424
D056987 Vasoplegia C00001424
D018754 Ventricular Dysfunction C00001424
D014693 Ventricular Fibrillation C00001424
D006934 Hypercalcemia C00037562
D001424 Bacterial Infections C00005413
D003092 Colitis C00005413
D015212 Inflammatory Bowel Diseases C00005413
D028361 Mitochondrial Diseases C00005413
D013276 Stomach Ulcer C00005413