PCIDB

KNApSAcK Metabolite C00001424

Metabolite

KNApSAcK Entry

id C00001424
Name Norepinephrine / L-Noradrenaline / (-)-Norepinephrine
CAS RN 51-41-2
Standard InChI InChI=1S/C8H11NO3/c9-4-8(12)5-1-2-6(10)7(11)3-5/h1-3,8,10-12H,4,9H2/t8-/m0/s1
Standard InChI (Main Layer) InChI=1S/C8H11NO3/c9-4-8(12)5-1-2-6(10)7(11)3-5/h1-3,8,10-12H,4,9H2

Cluster

Phytochemical cluster
KCF-S cluster No. 3197

Link

ChEMBL

By standard InChI CHEMBL1437
By standard InChI Main Layer CHEMBL432 CHEMBL18824 CHEMBL1437 CHEMBL2311152

KEGG

By LinkDB C00547

CTD

By CAS RN D009638

Human Protein / Gene in interaction

50 ChEMBL Protein in interactions

accession description class description compound assay ID (# of activities) # of diseases
(OMIM / KEGG)
Q9Y2I1 Nischarin Other cytosolic protein CHEMBL1437 CHEMBL841852 (1)
0 / 0
O15244 Solute carrier family 22 member 2 Drug uniporter CHEMBL1437 CHEMBL2076309 (1) CHEMBL2077787 (1)
CHEMBL2077788 (1)
0 / 0
P21728 D(1A) dopamine receptor Dopamine receptor CHEMBL432 CHEMBL1437 CHEMBL669035 (1) CHEMBL669037 (1)
CHEMBL1738091 (2) CHEMBL1737859 (1)
CHEMBL1738565 (2) CHEMBL2114744 (2)
0 / 0
Q13526 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 Enzyme CHEMBL18824 CHEMBL1437 CHEMBL1794585 (2)
0 / 0
Q99489 D-aspartate oxidase Enzyme CHEMBL1437 CHEMBL2327933 (1)
0 / 0
P02545 Prelamin-A/C Unclassified protein CHEMBL1437 CHEMBL1614544 (1)
11 / 10
P10828 Thyroid hormone receptor beta NR1A2 CHEMBL18824 CHEMBL1613776 (1)
3 / 1
P07550 Beta-2 adrenergic receptor Adrenergic receptor CHEMBL1437 CHEMBL647096 (1) CHEMBL651793 (1)
CHEMBL651795 (1) CHEMBL651652 (1)
CHEMBL650886 (1) CHEMBL652673 (1)
CHEMBL692356 (1) CHEMBL819727 (1)
CHEMBL819728 (1) CHEMBL1058735 (1)
CHEMBL1043293 (1)
0 / 1
P18825 Alpha-2C adrenergic receptor Adrenergic receptor CHEMBL1437 CHEMBL642033 (1) CHEMBL646081 (1)
CHEMBL646082 (1) CHEMBL642053 (1)
CHEMBL643443 (1) CHEMBL648617 (1)
CHEMBL918084 (1) CHEMBL918085 (1)
CHEMBL895082 (1) CHEMBL1016581 (1)
CHEMBL1047069 (1) CHEMBL1047075 (1)
0 / 0
P13945 Beta-3 adrenergic receptor Adrenergic receptor CHEMBL1437 CHEMBL647096 (1) CHEMBL651793 (1)
CHEMBL651795 (1) CHEMBL651652 (1)
CHEMBL652673 (1) CHEMBL692356 (1)
CHEMBL936719 (1) CHEMBL936720 (1)
CHEMBL936722 (1)
0 / 0
P14920 D-amino-acid oxidase Enzyme CHEMBL1437 CHEMBL2327932 (1)
0 / 0
P54132 Bloom syndrome protein Enzyme CHEMBL18824 CHEMBL1437 CHEMBL1614067 (2)
1 / 2
Q9NR56 Muscleblind-like protein 1 Unclassified protein CHEMBL1437 CHEMBL1738096 (1) CHEMBL1738622 (1)
1 / 0
P11473 Vitamin D3 receptor NR1I1 CHEMBL432 CHEMBL1437 CHEMBL1794311 (3)
2 / 3
P14416 D(2) dopamine receptor Dopamine receptor CHEMBL1437 CHEMBL671063 (1)
2 / 0
O15296 Arachidonate 15-lipoxygenase B Enzyme CHEMBL1437 CHEMBL1613800 (1)
0 / 0
P39748 Flap endonuclease 1 Enzyme CHEMBL432 CHEMBL1437 CHEMBL1613922 (2) CHEMBL1794486 (2)
0 / 0
Q92830 Histone acetyltransferase KAT2A Enzyme CHEMBL1437 CHEMBL1738606 (1)
0 / 0
P08913 Alpha-2A adrenergic receptor Adrenergic receptor CHEMBL1437 CHEMBL642033 (1) CHEMBL646081 (1)
CHEMBL646082 (1) CHEMBL647962 (1)
CHEMBL642053 (1) CHEMBL643443 (1)
CHEMBL918090 (1) CHEMBL918091 (1)
CHEMBL895080 (1) CHEMBL1015738 (1)
CHEMBL1047071 (1) CHEMBL1047078 (1)
CHEMBL1226895 (1) CHEMBL1228581 (1)
CHEMBL1228585 (1) CHEMBL1647738 (1)
CHEMBL1932426 (1) CHEMBL1932427 (1)
0 / 0
P35348 Alpha-1A adrenergic receptor Adrenergic receptor CHEMBL1437 CHEMBL873047 (1) CHEMBL643537 (1)
CHEMBL648744 (1) CHEMBL647013 (1)
CHEMBL652807 (1) CHEMBL663937 (1)
CHEMBL663939 (1) CHEMBL663943 (1)
CHEMBL663945 (1) CHEMBL663946 (1)
CHEMBL663947 (1) CHEMBL671863 (1)
CHEMBL845264 (1) CHEMBL845265 (1)
0 / 0
P43220 Glucagon-like peptide 1 receptor Glucagon-like peptide receptor CHEMBL1437 CHEMBL2114931 (1)
0 / 0
Q9GZT4 Serine racemase Enzyme CHEMBL1437 CHEMBL2327930 (1)
0 / 0
P83916 Chromobox protein homolog 1 Unclassified protein CHEMBL432 CHEMBL1738610 (1)
0 / 0
P50224 Sulfotransferase 1A3/1A4 Enzyme CHEMBL1437 CHEMBL1743305 (1)
0 / 0
O94782 Ubiquitin carboxyl-terminal hydrolase 1 Enzyme CHEMBL18824 CHEMBL1437 CHEMBL1794467 (2)
0 / 0
P28482 Mitogen-activated protein kinase 1 Erk CHEMBL18824 CHEMBL1613808 (1)
0 / 0
P15428 15-hydroxyprostaglandin dehydrogenase [NAD(+)] Enzyme CHEMBL18824 CHEMBL1437 CHEMBL1614038 (2)
2 / 2
Q96QE3 ATPase family AAA domain-containing protein 5 Unclassified protein CHEMBL432 CHEMBL1738675 (1)
0 / 0
P08588 Beta-1 adrenergic receptor Adrenergic receptor CHEMBL1437 CHEMBL651262 (1) CHEMBL647096 (1)
CHEMBL651793 (1) CHEMBL651795 (1)
CHEMBL651652 (1) CHEMBL652673 (1)
CHEMBL692356 (1)
1 / 0
P35372 Mu-type opioid receptor Opioid receptor CHEMBL1437 CHEMBL935496 (1)
0 / 0
P08684 Cytochrome P450 3A4 Cytochrome P450 3A4 CHEMBL18824 CHEMBL1614108 (1) CHEMBL1613886 (1)
0 / 1
O75164 Lysine-specific demethylase 4A Enzyme CHEMBL18824 CHEMBL1437 CHEMBL1737991 (2)
0 / 0
P27695 DNA-(apurinic or apyrimidinic site) lyase Enzyme CHEMBL18824 CHEMBL1437 CHEMBL1614466 (2) CHEMBL1614211 (4)
0 / 0
P10636 Microtubule-associated protein tau Unclassified protein CHEMBL18824 CHEMBL1437 CHEMBL1614250 (3) CHEMBL1613899 (1)
CHEMBL1614284 (1) CHEMBL1614365 (1)
CHEMBL1614421 (3) CHEMBL1614502 (2)
4 / 3
Q16236 Nuclear factor erythroid 2-related factor 2 Unclassified protein CHEMBL1437 CHEMBL2114890 (1)
0 / 0
P23975 Sodium-dependent noradrenaline transporter Norepinephrine CHEMBL1437 CHEMBL2311152 CHEMBL945607 (1) CHEMBL945608 (1)
CHEMBL1065538 (1)
1 / 1
P35368 Alpha-1B adrenergic receptor Adrenergic receptor CHEMBL1437 CHEMBL643537 (1) CHEMBL648744 (1)
CHEMBL647013 (1) CHEMBL845264 (1)
CHEMBL1043292 (1)
0 / 0
P18089 Alpha-2B adrenergic receptor Adrenergic receptor CHEMBL1437 CHEMBL642033 (1) CHEMBL646081 (1)
CHEMBL646082 (1) CHEMBL642053 (1)
CHEMBL643443 (1) CHEMBL918087 (1)
CHEMBL918088 (1) CHEMBL895081 (1)
CHEMBL1016577 (1) CHEMBL1047070 (1)
0 / 0
Q9UBT6 DNA polymerase kappa Enzyme CHEMBL432 CHEMBL18824 CHEMBL1437 CHEMBL1794536 (6)
0 / 0
B2RXH2 Lysine-specific demethylase 4E Enzyme CHEMBL18824 CHEMBL1613914 (1)
0 / 0
P46063 ATP-dependent DNA helicase Q1 Enzyme CHEMBL18824 CHEMBL1437 CHEMBL1613829 (3) CHEMBL1613928 (2)
0 / 0
Q96KQ7 Histone-lysine N-methyltransferase EHMT2 Enzyme CHEMBL432 CHEMBL1437 CHEMBL1738442 (4)
0 / 0
Q9NUW8 Tyrosyl-DNA phosphodiesterase 1 Enzyme CHEMBL18824 CHEMBL1437 CHEMBL1614364 (6) CHEMBL1738394 (1)
1 / 1
O00255 Menin Unclassified protein CHEMBL1437 CHEMBL1614257 (1)
2 / 5
Q03164 Histone-lysine N-methyltransferase 2A Enzyme CHEMBL1437 CHEMBL1614257 (1)
1 / 3
Q13951 Core-binding factor subunit beta Unclassified protein CHEMBL18824 CHEMBL1738090 (1) CHEMBL1737904 (1)
0 / 1
Q01196 Runt-related transcription factor 1 Unclassified protein CHEMBL18824 CHEMBL1738090 (1) CHEMBL1737904 (1)
1 / 6
O75751 Solute carrier family 22 member 3 Unclassified protein CHEMBL1437 CHEMBL2077213 (1)
0 / 0
P25100 Alpha-1D adrenergic receptor Adrenergic receptor CHEMBL1437 CHEMBL643537 (1) CHEMBL648744 (1)
CHEMBL647013 (1) CHEMBL845265 (1)
0 / 0
O94925 Glutaminase kidney isoform, mitochondrial Enzyme CHEMBL1437 CHEMBL2114738 (1)
0 / 0

CTD interaction (94)

compound gene gene name gene description interaction interaction type form reference
pmid
D009638 148 ADRA1A
ADRA1C
ADRA1L1
ALPHA1AAR
adrenoceptor alpha 1A Norepinephrine binds to ADRA1A protein affects binding
protein 8183249
D009638 148 ADRA1A
ADRA1C
ADRA1L1
ALPHA1AAR
adrenoceptor alpha 1A Norepinephrine binds to and results in increased activity of ADRA1A protein affects binding
/ increases activity
protein 20030735
D009638 148 ADRA1A
ADRA1C
ADRA1L1
ALPHA1AAR
adrenoceptor alpha 1A [Norepinephrine binds to and results in increased activity of ADRA1A protein] which results in increased abundance of Calcium affects binding
/ increases abundance
/ increases activity
protein 20030735
D009638 148 ADRA1A
ADRA1C
ADRA1L1
ALPHA1AAR
adrenoceptor alpha 1A Norepinephrine inhibits the reaction [ADRA1A protein binds to Prazosin] affects binding
/ decreases reaction
protein 20030735
D009638 147 ADRA1B
ADRA1
ALPHA1BAR
adrenoceptor alpha 1B Norepinephrine binds to and results in increased activity of ADRA1B protein affects binding
/ increases activity
protein 20030735
D009638 147 ADRA1B
ADRA1
ALPHA1BAR
adrenoceptor alpha 1B [Norepinephrine binds to and results in increased activity of ADRA1B protein] which results in increased abundance of Calcium affects binding
/ increases abundance
/ increases activity
protein 20030735
D009638 147 ADRA1B
ADRA1
ALPHA1BAR
adrenoceptor alpha 1B Norepinephrine inhibits the reaction [ADRA1B protein binds to Prazosin] affects binding
/ decreases reaction
protein 20030735
D009638 146 ADRA1D
ADRA1
ADRA1A
ADRA1R
ALPHA1
DAR
dJ779E11.2
adrenoceptor alpha 1D Norepinephrine binds to ADRA1D protein affects binding
protein 8183249
15493479
D009638 146 ADRA1D
ADRA1
ADRA1A
ADRA1R
ALPHA1
DAR
dJ779E11.2
adrenoceptor alpha 1D Norepinephrine binds to and results in increased activity of ADRA1D protein affects binding
/ increases activity
protein 20030735
D009638 146 ADRA1D
ADRA1
ADRA1A
ADRA1R
ALPHA1
DAR
dJ779E11.2
adrenoceptor alpha 1D [Norepinephrine binds to and results in increased activity of ADRA1D protein] which results in increased abundance of Calcium affects binding
/ increases abundance
/ increases activity
protein 20030735
D009638 146 ADRA1D
ADRA1
ADRA1A
ADRA1R
ALPHA1
DAR
dJ779E11.2
adrenoceptor alpha 1D Norepinephrine inhibits the reaction [ADRA1D protein binds to Prazosin] affects binding
/ decreases reaction
protein 20030735
D009638 150 ADRA2A
ADRA2
ADRA2R
ADRAR
ALPHA2AAR
ZNF32
adrenoceptor alpha 2A 1-(6-((3-methoxyestra-1,3,5(10)-trien-17-yl)amino)hexyl)-1H-pyrrole-2,5-dione inhibits the reaction [Norepinephrine binds to and results in increased activity of ADRA2A protein] affects binding
/ decreases reaction
/ increases activity
protein 10742289
D009638 150 ADRA2A
ADRA2
ADRA2R
ADRAR
ALPHA2AAR
ZNF32
adrenoceptor alpha 2A brimonidine inhibits the reaction [Norepinephrine binds to and results in increased activity of ADRA2A protein] affects binding
/ decreases reaction
/ increases activity
protein 10742289
D009638 150 ADRA2A
ADRA2
ADRA2R
ADRAR
ALPHA2AAR
ZNF32
adrenoceptor alpha 2A Dexmedetomidine inhibits the reaction [Norepinephrine binds to and results in increased activity of ADRA2A protein] affects binding
/ decreases reaction
/ increases activity
protein 10742289
D009638 150 ADRA2A
ADRA2
ADRA2R
ADRAR
ALPHA2AAR
ZNF32
adrenoceptor alpha 2A Doxazosin inhibits the reaction [Norepinephrine binds to and results in increased activity of ADRA2A protein] affects binding
/ decreases reaction
/ increases activity
protein 10742289
D009638 150 ADRA2A
ADRA2
ADRA2R
ADRAR
ALPHA2AAR
ZNF32
adrenoceptor alpha 2A Norepinephrine binds to and results in increased activity of ADRA2A protein affects binding
/ increases activity
protein 10742289
20030735
D009638 150 ADRA2A
ADRA2
ADRA2R
ADRAR
ALPHA2AAR
ZNF32
adrenoceptor alpha 2A [Norepinephrine binds to and results in increased activity of ADRA2A protein] which results in increased abundance of Calcium affects binding
/ increases abundance
/ increases activity
protein 20030735
D009638 150 ADRA2A
ADRA2
ADRA2R
ADRAR
ALPHA2AAR
ZNF32
adrenoceptor alpha 2A Norepinephrine inhibits the reaction [ADRA2A protein binds to 2-methoxyidazoxan] affects binding
/ decreases reaction
protein 20030735
D009638 150 ADRA2A
ADRA2
ADRA2R
ADRAR
ALPHA2AAR
ZNF32
adrenoceptor alpha 2A Prazosin inhibits the reaction [Norepinephrine binds to and results in increased activity of ADRA2A protein] affects binding
/ decreases reaction
/ increases activity
protein 10742289
D009638 150 ADRA2A
ADRA2
ADRA2R
ADRAR
ALPHA2AAR
ZNF32
adrenoceptor alpha 2A talipexole inhibits the reaction [Norepinephrine binds to and results in increased activity of ADRA2A protein] affects binding
/ decreases reaction
/ increases activity
protein 10742289
D009638 150 ADRA2A
ADRA2
ADRA2R
ADRAR
ALPHA2AAR
ZNF32
adrenoceptor alpha 2A Thapsigargin inhibits the reaction [Norepinephrine binds to and results in increased activity of ADRA2A protein] affects binding
/ decreases reaction
/ increases activity
protein 10742289
D009638 150 ADRA2A
ADRA2
ADRA2R
ADRAR
ALPHA2AAR
ZNF32
adrenoceptor alpha 2A Yohimbine inhibits the reaction [Norepinephrine binds to and results in increased activity of ADRA2A protein] affects binding
/ decreases reaction
/ increases activity
protein 10742289
D009638 151 ADRA2B
ADRA2L1
ADRA2RL1
ADRARL1
ALPHA2BAR
alpha-2BAR
adrenoceptor alpha 2B Norepinephrine binds to and results in increased activity of ADRA2B protein affects binding
/ increases activity
protein 20030735
D009638 151 ADRA2B
ADRA2L1
ADRA2RL1
ADRARL1
ALPHA2BAR
alpha-2BAR
adrenoceptor alpha 2B [Norepinephrine binds to and results in increased activity of ADRA2B protein] which results in increased abundance of Calcium affects binding
/ increases abundance
/ increases activity
protein 20030735
D009638 151 ADRA2B
ADRA2L1
ADRA2RL1
ADRARL1
ALPHA2BAR
alpha-2BAR
adrenoceptor alpha 2B Norepinephrine inhibits the reaction [ADRA2B protein binds to 2-methoxyidazoxan] affects binding
/ decreases reaction
protein 20030735
D009638 152 ADRA2C
ADRA2L2
ADRA2RL2
ADRARL2
ALPHA2CAR
adrenoceptor alpha 2C Norepinephrine binds to and results in increased activity of ADRA2C protein affects binding
/ increases activity
protein 20030735
D009638 152 ADRA2C
ADRA2L2
ADRA2RL2
ADRARL2
ALPHA2CAR
adrenoceptor alpha 2C [Norepinephrine binds to and results in increased activity of ADRA2C protein] which results in increased abundance of Calcium affects binding
/ increases abundance
/ increases activity
protein 20030735
D009638 152 ADRA2C
ADRA2L2
ADRA2RL2
ADRARL2
ALPHA2CAR
adrenoceptor alpha 2C Norepinephrine inhibits the reaction [ADRA2C protein binds to 2-methoxyidazoxan] affects binding
/ decreases reaction
protein 20030735
D009638 153 ADRB1
ADRB1R
B1AR
BETA1AR
RHR
adrenoceptor beta 1 Norepinephrine binds to and results in increased activity of ADRB1 protein affects binding
/ increases activity
protein 10344530
14730417
17200720
D009638 153 ADRB1
ADRB1R
B1AR
BETA1AR
RHR
adrenoceptor beta 1 [Norepinephrine binds to and results in increased activity of ADRB1 protein] which results in increased abundance of Cyclic AMP affects binding
/ increases abundance
/ increases activity
protein 14730417
17200720
D009638 153 ADRB1
ADRB1R
B1AR
BETA1AR
RHR
adrenoceptor beta 1 Norepinephrine inhibits the reaction [cyanopindolol binds to ADRB1 protein] affects binding
/ decreases reaction
protein 14730417
D009638 153 ADRB1
ADRB1R
B1AR
BETA1AR
RHR
adrenoceptor beta 1 Norepinephrine inhibits the reaction [Iodocyanopindolol binds to ADRB1 protein] affects binding
/ decreases reaction
protein 8096834
D009638 153 ADRB1
ADRB1R
B1AR
BETA1AR
RHR
adrenoceptor beta 1 Norepinephrine promotes the reaction [ADRB1 protein results in increased activity of GNAS protein] increases activity
/ increases reaction
protein 17200720
D009638 153 ADRB1
ADRB1R
B1AR
BETA1AR
RHR
adrenoceptor beta 1 Octopamine inhibits the reaction [Norepinephrine binds to ADRB1 protein] affects binding
/ decreases reaction
protein 10344530
D009638 153 ADRB1
ADRB1R
B1AR
BETA1AR
RHR
adrenoceptor beta 1 Propranolol inhibits the reaction [Norepinephrine binds to and results in increased activity of ADRB1 protein] affects binding
/ decreases reaction
/ increases activity
protein 17200720
D009638 154 ADRB2
ADRB2R
ADRBR
B2AR
BAR
BETA2AR
adrenoceptor beta 2, surface Norepinephrine binds to and results in increased activity of ADRB2 protein affects binding
/ increases activity
protein 10344530
14730417
D009638 154 ADRB2
ADRB2R
ADRBR
B2AR
BAR
BETA2AR
adrenoceptor beta 2, surface [Norepinephrine binds to and results in increased activity of ADRB2 protein] which results in increased abundance of Cyclic AMP affects binding
/ increases abundance
/ increases activity
protein 14730417
D009638 154 ADRB2
ADRB2R
ADRBR
B2AR
BAR
BETA2AR
adrenoceptor beta 2, surface Norepinephrine inhibits the reaction [cyanopindolol binds to ADRB2 protein] affects binding
/ decreases reaction
protein 14730417
D009638 154 ADRB2
ADRB2R
ADRBR
B2AR
BAR
BETA2AR
adrenoceptor beta 2, surface Octopamine inhibits the reaction [Norepinephrine binds to ADRB2 protein] affects binding
/ decreases reaction
protein 10344530
D009638 155 ADRB3
BETA3AR
adrenoceptor beta 3 Norepinephrine binds to and results in increased activity of ADRB3 protein affects binding
/ increases activity
protein 1682311
14730417
D009638 155 ADRB3
BETA3AR
adrenoceptor beta 3 [Norepinephrine binds to and results in increased activity of ADRB3 protein] which results in increased abundance of Cyclic AMP affects binding
/ increases abundance
/ increases activity
protein 14730417
D009638 155 ADRB3
BETA3AR
adrenoceptor beta 3 Norepinephrine inhibits the reaction [cyanopindolol binds to ADRB3 protein] affects binding
/ decreases reaction
protein 14730417
D009638 155 ADRB3
BETA3AR
adrenoceptor beta 3 Octopamine inhibits the reaction [Norepinephrine binds to ADRB3 protein] affects binding
/ decreases reaction
protein 10344530
D009638 836 CASP3
CPP32
CPP32B
SCA-1
caspase 3, apoptosis-related cysteine peptidase (EC:3.4.22.56) Acetylcysteine inhibits the reaction [Norepinephrine results in increased activity of and results in increased cleavage of CASP3 protein] decreases reaction
/ increases activity
/ increases cleavage
protein 17136323
D009638 836 CASP3
CPP32
CPP32B
SCA-1
caspase 3, apoptosis-related cysteine peptidase (EC:3.4.22.56) Norepinephrine results in increased activity of and results in increased cleavage of CASP3 protein increases activity
/ increases cleavage
protein 17136323
D009638 840 CASP7
CASP-7
CMH-1
ICE-LAP3
LICE2
MCH3
caspase 7, apoptosis-related cysteine peptidase (EC:3.4.22.60) Acetylcysteine inhibits the reaction [Norepinephrine results in increased activity of and results in increased cleavage of CASP7 protein] decreases reaction
/ increases activity
/ increases cleavage
protein 17136323
D009638 840 CASP7
CASP-7
CMH-1
ICE-LAP3
LICE2
MCH3
caspase 7, apoptosis-related cysteine peptidase (EC:3.4.22.60) Norepinephrine results in increased activity of and results in increased cleavage of CASP7 protein increases activity
/ increases cleavage
protein 17136323
D009638 6352 CCL5
D17S136E
RANTES
SCYA5
SIS-delta
SISd
TCP228
eoCP
chemokine (C-C motif) ligand 5 Norepinephrine results in increased secretion of CCL5 protein increases secretion
protein 16782692
D009638 6352 CCL5
D17S136E
RANTES
SCYA5
SIS-delta
SISd
TCP228
eoCP
chemokine (C-C motif) ligand 5 Prazosin inhibits the reaction [Norepinephrine results in increased secretion of CCL5 protein] decreases reaction
/ increases secretion
protein 16782692
D009638 1312 COMT
catechol-O-methyltransferase (EC:2.1.1.6) COMT protein results in increased methylation of Norepinephrine increases methylation
protein 11160877
D009638 1312 COMT
catechol-O-methyltransferase (EC:2.1.1.6) [tolcapone results in decreased activity of COMT protein] which results in increased abundance of Norepinephrine decreases activity
/ increases abundance
protein 11248589
D009638 1813 DRD2
D2DR
D2R
dopamine receptor D2 [Norepinephrine binds to and results in increased activity of DRD2 protein alternative form] which results in decreased transport of Calcium affects binding
/ decreases transport
/ increases activity
protein 8032591
D009638 1813 DRD2
D2DR
D2R
dopamine receptor D2 Sulpiride inhibits the reaction [[Norepinephrine binds to and results in increased activity of DRD2 protein alternative form] which results in decreased transport of Calcium] affects binding
/ decreases reaction
/ decreases transport
/ increases activity
protein 8032591
D009638 2335 FN1
CIG
ED-B
FINC
FN
FNZ
GFND
GFND2
LETS
MSF
fibronectin 1 [Norepinephrine co-treated with Prazosin] results in decreased expression of FN1 protein affects cotreatment
/ decreases expression
protein 11821714
D009638 2335 FN1
CIG
ED-B
FINC
FN
FNZ
GFND
GFND2
LETS
MSF
fibronectin 1 [Norepinephrine co-treated with Propranolol] results in increased expression of FN1 protein affects cotreatment
/ increases expression
protein 11821714
D009638 2778 GNAS
AHO
C20orf45
GNAS1
GPSA
GSA
GSP
NESP
PHP1A
PHP1B
PHP1C
POH
GNAS complex locus Norepinephrine promotes the reaction [ADRB1 protein results in increased activity of GNAS protein] increases activity
/ increases reaction
protein 17200720
D009638 3569 IL6
BSF2
HGF
HSF
IFNB2
IL-6
interleukin 6 (interferon, beta 2) Norepinephrine results in increased expression of and results in increased secretion of IL6 protein increases expression
/ increases secretion
protein 18636164
D009638 3569 IL6
BSF2
HGF
HSF
IFNB2
IL-6
interleukin 6 (interferon, beta 2) sulforafan inhibits the reaction [Norepinephrine results in increased expression of and results in increased secretion of IL6 protein] decreases reaction
/ increases expression
/ increases secretion
protein 18636164
D009638 3576 IL8
CXCL8
GCP-1
GCP1
LECT
LUCT
LYNAP
MDNCF
MONAP
NAF
NAP-1
NAP1
interleukin 8 3-(4-methylphenylsulfonyl)-2-propenenitrile inhibits the reaction [Norepinephrine results in increased secretion of IL8 protein] decreases reaction
/ increases secretion
protein 16782692
D009638 3576 IL8
CXCL8
GCP-1
GCP1
LECT
LUCT
LYNAP
MDNCF
MONAP
NAF
NAP-1
NAP1
interleukin 8 Prazosin inhibits the reaction [Norepinephrine results in increased secretion of IL8 protein] decreases reaction
/ increases secretion
protein 16782692
D009638 4128 MAOA
MAO-A
monoamine oxidase A (EC:1.4.3.4) MAOA protein results in increased metabolism of Norepinephrine increases metabolic processing
protein 10647887
D009638 5594 MAPK1
ERK
ERK2
ERT1
MAPK2
P42MAPK
PRKM1
PRKM2
p38
p40
p41
p41mapk
mitogen-activated protein kinase 1 (EC:2.7.11.24) Norepinephrine inhibits the reaction [Estradiol results in decreased phosphorylation of MAPK1 protein] decreases phosphorylation
/ decreases reaction
protein 15292328
D009638 5595 MAPK3
ERK-1
ERK1
ERT2
HS44KDAP
HUMKER1A
P44ERK1
P44MAPK
PRKM3
p44-ERK1
p44-MAPK
mitogen-activated protein kinase 3 (EC:2.7.11.24) Norepinephrine inhibits the reaction [Estradiol results in decreased phosphorylation of MAPK3 protein] decreases phosphorylation
/ decreases reaction
protein 15292328
D009638 4790 NFKB1
EBP-1
KBF1
NF-kB1
NF-kappa-B
NF-kappaB
NFKB-p105
NFKB-p50
NFkappaB
p105
p50
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 Norepinephrine affects the localization of [NFKB1 protein binds to RELA protein] affects binding
/ affects localization
protein 16782692
D009638 4790 NFKB1
EBP-1
KBF1
NF-kB1
NF-kappa-B
NF-kappaB
NFKB-p105
NFKB-p50
NFkappaB
p105
p50
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 Norepinephrine results in increased activity of [NFKB1 protein binds to RELA protein] affects binding
/ increases activity
protein 16782692
D009638 4879 NPPB
BNP
natriuretic peptide B NPPB affects the abundance of Norepinephrine affects abundance
20339970
D009638 4879 NPPB
BNP
natriuretic peptide B NPPB protein results in decreased abundance of Norepinephrine decreases abundance
protein 16333235
D009638 4852 NPY
PYY4
neuropeptide Y NPY protein affects the susceptibility to Norepinephrine affects response to substance
protein 15003356
D009638 5970 RELA
NFKB3
p65
v-rel avian reticuloendotheliosis viral oncogene homolog A Norepinephrine affects the localization of [NFKB1 protein binds to RELA protein] affects binding
/ affects localization
protein 16782692
D009638 5970 RELA
NFKB3
p65
v-rel avian reticuloendotheliosis viral oncogene homolog A Norepinephrine results in increased activity of [NFKB1 protein binds to RELA protein] affects binding
/ increases activity
protein 16782692
D009638 6279 S100A8
60B8AG
CAGA
CFAG
CGLA
CP-10
L1Ag
MA387
MIF
MRP8
NIF
P8
S100 calcium binding protein A8 Norepinephrine results in increased expression of S100A8 mRNA increases expression
mRNA 16677282
D009638 6279 S100A8
60B8AG
CAGA
CFAG
CGLA
CP-10
L1Ag
MA387
MIF
MRP8
NIF
P8
S100 calcium binding protein A8 Norepinephrine results in increased expression of S100A8 protein increases expression
protein 16677282
D009638 6280 S100A9
60B8AG
CAGB
CFAG
CGLB
L1AG
LIAG
MAC387
MIF
MRP14
NIF
P14
S100 calcium binding protein A9 Norepinephrine results in increased expression of S100A9 mRNA increases expression
mRNA 16677282
D009638 6280 S100A9
60B8AG
CAGB
CFAG
CGLB
L1AG
LIAG
MAC387
MIF
MRP14
NIF
P14
S100 calcium binding protein A9 Norepinephrine results in increased expression of S100A9 protein increases expression
protein 16677282
D009638 6285 S100B
NEF
S100
S100-B
S100beta
S100 calcium binding protein B Norepinephrine results in increased expression of S100B mRNA increases expression
mRNA 9788975
D009638 6285 S100B
NEF
S100
S100-B
S100beta
S100 calcium binding protein B Norepinephrine results in increased expression of S100B protein increases expression
protein 9788975
D009638 6285 S100B
NEF
S100
S100-B
S100beta
S100 calcium binding protein B S100B protein affects the susceptibility to Norepinephrine affects response to substance
protein 9788975
D009638 6570 SLC18A1
CGAT
VAT1
VMAT1
solute carrier family 18 (vesicular monoamine transporter), member 1 Norepinephrine inhibits the reaction [SLC18A1 protein results in increased uptake of Serotonin] decreases reaction
/ increases uptake
protein 8245983
D009638 6571 SLC18A2
SVAT
SVMT
VAT2
VMAT2
solute carrier family 18 (vesicular monoamine transporter), member 2 Norepinephrine binds to SLC18A2 protein affects binding
protein 7912402
D009638 6571 SLC18A2
SVAT
SVMT
VAT2
VMAT2
solute carrier family 18 (vesicular monoamine transporter), member 2 Norepinephrine results in decreased activity of SLC18A2 protein decreases activity
protein 15475732
D009638 6530 SLC6A2
NAT1
NET
NET1
SLC6A5
solute carrier family 6 (neurotransmitter transporter), member 2 Norepinephrine inhibits the reaction [nisoxetine binds to SLC6A2 protein] affects binding
/ decreases reaction
protein 11082428
D009638 6530 SLC6A2
NAT1
NET
NET1
SLC6A5
solute carrier family 6 (neurotransmitter transporter), member 2 Norepinephrine results in decreased activity of SLC6A2 protein decreases activity
protein 11082428
D009638 6530 SLC6A2
NAT1
NET
NET1
SLC6A5
solute carrier family 6 (neurotransmitter transporter), member 2 Norepinephrine results in decreased expression of SLC6A2 protein decreases expression
protein 11082428
D009638 6530 SLC6A2
NAT1
NET
NET1
SLC6A5
solute carrier family 6 (neurotransmitter transporter), member 2 SLC6A2 mutant form results in decreased uptake of Norepinephrine decreases uptake
mutant form 11458707
D009638 6530 SLC6A2
NAT1
NET
NET1
SLC6A5
solute carrier family 6 (neurotransmitter transporter), member 2 SLC6A2 protein promotes the reaction [Norepinephrine results in increased activity of TAAR1 protein] increases activity
/ increases reaction
protein 17234900
D009638 6531 SLC6A3
DAT
DAT1
PKDYS
solute carrier family 6 (neurotransmitter transporter), member 3 SLC6A3 protein promotes the reaction [Norepinephrine results in increased activity of TAAR1 protein] increases activity
/ increases reaction
protein 17234900
D009638 6531 SLC6A3
DAT
DAT1
PKDYS
solute carrier family 6 (neurotransmitter transporter), member 3 SLC6A3 protein results in increased uptake of Norepinephrine increases uptake
protein 17250655
D009638 6532 SLC6A4
5-HTT
5-HTTLPR
5HTT
HTT
OCD1
SERT
SERT1
hSERT
solute carrier family 6 (neurotransmitter transporter), member 4 SLC6A4 protein promotes the reaction [Norepinephrine results in increased activity of TAAR1 protein] increases activity
/ increases reaction
protein 17234900
D009638 6818 SULT1A3
HAST
HAST3
M-PST
ST1A3/ST1A4
ST1A5
STM
TL-PST
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 3 (EC:2.8.2.1) SULT1A3 protein results in increased sulfation of Norepinephrine increases sulfation
protein 11181495
D009638 134864 TAAR1
RP11-295F4.9
TA1
TAR1
TRAR1
trace amine associated receptor 1 SLC6A2 protein promotes the reaction [Norepinephrine results in increased activity of TAAR1 protein] increases activity
/ increases reaction
protein 17234900
D009638 134864 TAAR1
RP11-295F4.9
TA1
TAR1
TRAR1
trace amine associated receptor 1 SLC6A3 protein promotes the reaction [Norepinephrine results in increased activity of TAAR1 protein] increases activity
/ increases reaction
protein 17234900
D009638 134864 TAAR1
RP11-295F4.9
TA1
TAR1
TRAR1
trace amine associated receptor 1 SLC6A4 protein promotes the reaction [Norepinephrine results in increased activity of TAAR1 protein] increases activity
/ increases reaction
protein 17234900
D009638 7391 USF1
FCHL
FCHL1
HYPLIP1
MLTF
MLTFI
UEF
bHLHb11
upstream transcription factor 1 USF1 gene polymorphism promotes the reaction [Norepinephrine results in increased metabolism of Lipids] increases metabolic processing
/ increases reaction
gene 15985485
D009638 7391 USF1
FCHL
FCHL1
HYPLIP1
MLTF
MLTFI
UEF
bHLHb11
upstream transcription factor 1 USF1 protein affects the reaction [Norepinephrine results in increased metabolism of Lipids] affects reaction
/ increases metabolic processing
protein 15985485

Related Disease

Diseases related to proteins in ChEMBL interactions

OMIM (33)

OMIM preferred title UniProt
#103780 Alcohol dependence P14416
#210900 Bloom syndrome; blm P54132
#115200 Cardiomyopathy, dilated, 1a; cmd1a P02545
#212112 Cardiomyopathy, dilated, with hypergonadotropic hypogonadism P02545
#605588 Charcot-marie-tooth disease, axonal, type 2b1; cmt2b1 P02545
#119900 Digital clubbing, isolated congenital P15428
#181350 Emery-dreifuss muscular dystrophy 2, autosomal dominant; edmd2 P02545
#600274 Frontotemporal dementia; ftd P10636
#605130 Hairy elbows, short stature, facial dysmorphism, and developmental delay Q03164
#610140 Heart-hand syndrome, slovenian type P02545
#176670 Hutchinson-gilford progeria syndrome; hgps P02545
#145000 Hyperparathyroidism 1; hrpt1 O00255
#259100 Hypertrophic osteoarthropathy, primary, autosomal recessive, 1; phoar1 P15428
#151660 Lipodystrophy, familial partial, type 2; fpld2 P02545
#248370 Mandibuloacral dysplasia with type a lipodystrophy; mada P02545
#131100 Multiple endocrine neoplasia, type i; men1 O00255
#613205 Muscular dystrophy, congenital, lmna-related P02545
#159001 Muscular dystrophy, limb-girdle, type 1b; lgmd1b P02545
#607948 Mycobacterium tuberculosis, susceptibility to P11473
#159900 Myoclonic dystonia P14416
#160900 Myotonic dystrophy 1; dm1 Q9NR56
#604715 Orthostatic intolerance P23975
#260540 Parkinson-dementia syndrome P10636
#172700 Pick disease of brain P10636
#601399 Platelet disorder, familial, with associated myeloid malignancy Q01196
#607276 Resting heart rate, variation in P08588
#275210 Restrictive dermopathy, lethal P02545
#607250 Spinocerebellar ataxia, autosomal recessive, with axonal neuropathy; scan1 Q9NUW8
#601104 Supranuclear palsy, progressive, 1; psnp1 P10636
#188570 Thyroid hormone resistance, generalized, autosomal dominant; grth P10828
#274300 Thyroid hormone resistance, generalized, autosomal recessive; grth P10828
#145650 Thyroid hormone resistance, selective pituitary; prth P10828
#277440 Vitamin d-dependent rickets, type 2a; vddr2a P11473

KEGG DISEASE (35)

KEGG disease name UniProt
H00033 Adrenal carcinoma O00255 (related)
H00034 Carcinoid O00255 (related)
H00045 Malignant islet cell carcinoma O00255 (related)
H00246 Primary hyperparathyroidism O00255 (related)
H01102 Pituitary adenomas O00255 (related)
H00264 Charcot-Marie-Tooth disease (CMT) P02545 (related)
H00294 Dilated cardiomyopathy (DCM) P02545 (related)
H00420 Familial partial lipodystrophy (FPL) P02545 (related)
H00563 Emery-Dreifuss muscular dystrophy P02545 (related)
H00590 Congenital muscular dystrophies (CMD/MDC) P02545 (related)
H00593 Limb-girdle muscular dystrophy (LGMD) P02545 (related)
H00601 Hutchinson-Gilford progeria syndrome P02545 (related)
H00663 Restrictive dermopathy P02545 (related)
H00665 Mandibuloacral dysplasia P02545 (related)
H01216 Left ventricular noncompaction (LVNC) P02545 (related)
H00079 Asthma P07550 (related)
H00036 Osteosarcoma P08684 (marker)
H00058 Amyotrophic lateral sclerosis (ALS) P10636 (related)
H00077 Progressive supranuclear palsy (PSP) P10636 (related)
H00078 Frontotemporal lobar degeneration (FTLD) P10636 (related)
H00249 Thyroid hormone resistance syndrome P10828 (related)
H00342 Tuberculosis P11473 (related)
H00784 Localized autosomal recessive hypotrichosis P11473 (related)
H01143 Vitamin D-dependent rickets P11473 (related)
H00457 Primary hypertrophic osteoarthropathy (PHO) P15428 (related)
H01246 Isolated congenital nail clubbing (ICNC) P15428 (related)
H01031 Orthostatic intolerance (OI) P23975 (related)
H00094 DNA repair defects P54132 (related)
H00296 Defects in RecQ helicases P54132 (related)
H00001 Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) Q01196 (related)
Q01196 (marker)
Q03164 (related)
Q03164 (marker)
H00003 Acute myeloid leukemia (AML) Q01196 (related)
Q01196 (marker)
Q13951 (marker)
H00004 Chronic myeloid leukemia (CML) Q01196 (related)
H00978 Thrombocytopenia (THC) Q01196 (related)
H00002 Acute lymphoblastic leukemia (ALL) (precursor T lymphoblastic leukemia) Q03164 (related)
H00063 Spinocerebellar ataxia (SCA) Q9NUW8 (related)

Diseases related to CTD interactions

90 disease from interactions of metabolites

MeSH disease OMIM compound disease name evidence type reference
pmid
D058186 D009638 Acute Kidney Injury marker/mechanism
513486
618599
668387
686175
691972
691976
735158
1102487
2139164
2243129
2946967
2948068
3015452
3573537
3706779
5034334
6652879
6720897
6769339
7419955
D000647 D009638 Amnesia therapeutic
561405
19041726
D019969 D009638 Amphetamine-Related Disorders marker/mechanism
9205790
D017542 D009638 Aneurysm, Ruptured marker/mechanism
2775019
D000860 D009638 Anoxia marker/mechanism
11311734
D001002 D009638 Anuria marker/mechanism
2948068
D001008 D009638 Anxiety Disorders marker/mechanism
6939007
D001145 D009638 Arrhythmias, Cardiac marker/mechanism
3791353
6744105
7627047
15079024
D001237 D009638 Asphyxia therapeutic
238228
D001321 D009638 Autistic Disorder marker/mechanism
8570775
D001766 D009638 Blindness marker/mechanism
3692857
D001919 D009638 Bradycardia marker/mechanism
therapeutic
869641
959464
1122937
1255483
1355091
1953698
2867949
3616437
7301221
8302145
16803915
D002545 D009638 Brain Ischemia marker/mechanism
8099768
D002037 D009638 Bundle-Branch Block therapeutic
11089775
D002100 D009638 Cachexia marker/mechanism
14966787
D002303 D009638 Cardiac Output, Low marker/mechanism
3677452
D006332 D009638 Cardiomegaly marker/mechanism
11179087
11940550
16124610
20374255
D009202 D009638 Cardiomyopathies marker/mechanism
20513218
D002375 D009638 Catalepsy therapeutic
8216760
D002543 D009638 Cerebral Hemorrhage marker/mechanism
15079024
D019970 D009638 Cocaine-Related Disorders marker/mechanism
18985323
D003922 D009638 Diabetes Mellitus, Type 1 marker/mechanism
6735272
D004409 D009638 Dyskinesia, Drug-Induced marker/mechanism
19146929
D004421 D009638 Dystonia marker/mechanism
1666503
1667258
D004827 D009638 Epilepsy therapeutic
821787
D005901 D009638 Glaucoma therapeutic
1138682
D005921 D009638 Glomerulonephritis marker/mechanism
11459117
D005923 D009638 Glomerulosclerosis, Focal Segmental marker/mechanism
19858406
D006261 D009638 Headache marker/mechanism
therapeutic
276963
2880686
D006323 D009638 Heart Arrest therapeutic
7762840
19097734
D006331 D009638 Heart Diseases marker/mechanism
3791353
5073842
6131755
D006333 D009638 Heart Failure marker/mechanism
7436166
7586371
9751683
12025466
12628948
15158148
16091638
D006470 D009638 Hemorrhage therapeutic
433043
D006930 D009638 Hyperalgesia marker/mechanism
2128375
3061568
8577481
9613798
10204755
16151601
D006935 D009638 Hypercapnia marker/mechanism
11311734
D006940 D009638 Hyperemia marker/mechanism
1138682
1581859
7949234
9277469
D006973 D009638 Hypertension marker/mechanism
43064
232021
282104
433043
525373
811997
1033105
1071667
1106169
1355091
1595107
1849535
1850525
1875449
1908657
1926237
2024278
2089934
2427882
2455169
2468958
2778312
2801151
3053895
3113166
3260082
3677452
3734443
3766759
5870364
6131755
6138461
6160942
6215903
6268123
6279499
6302156
6367368
6690337
6735272
6742791
6861444
7068199
7249534
7301221
7856916
7915249
7944421
8097719
8711809
8816361
8859936
8952593
9005172
9024144
9037424
9194512
9788975
9854457
10400907
11321437
11459117
12297708
14751847
14871037
15278610
15834284
16788141
17259435
17502491
17645634
18768397
19097734
19109942
19858406
20665428
D006974 D009638 Hypertension, Malignant marker/mechanism
6373596
D006976 D009638 Hypertension, Pulmonary marker/mechanism
7549228
D006984 D009638 Hypertrophy marker/mechanism
9788975
21756902
D017379 D009638 Hypertrophy, Left Ventricular marker/mechanism
8859936
10353135
10722803
11501170
14577597
14751847
16864425
20374255
D007008 D009638 Hypokalemia marker/mechanism
8734244
D007022 D009638 Hypotension marker/mechanism
therapeutic
1934231
2468958
2596658
2880686
2900909
2923291
3078272
3536153
3718622
3802857
6117801
6481092
6542785
6691577
6740701
6756847
7353333
7911308
8031432
8346819
8610874
8816361
9445295
10563144
12892164
15518130
15618781
16188828
16675238
16803915
17125115
17220694
17620917
19049484
19299808
D007024 D009638 Hypotension, Orthostatic marker/mechanism
8422659
D007035 D009638 Hypothermia marker/mechanism
959464
D007511 D009638 Ischemia marker/mechanism
686175
691976
3706779
6652879
D007674 D009638 Kidney Diseases marker/mechanism
6156352
D008113 D009638 Liver Neoplasms therapeutic
1530348
1908657
7944421
D008114 D009638 Liver Neoplasms, Experimental marker/mechanism
15687
D009203 D009638 Myocardial Infarction marker/mechanism
590420
624319
1849082
4163310
D017202 D009638 Myocardial Ischemia marker/mechanism
therapeutic
4825226
17620917
D015428 D009638 Myocardial Reperfusion Injury marker/mechanism
15642760
D009336 D009638 Necrosis marker/mechanism
2764457
3706779
3791353
3894677
6033906
6131755
D009410 D009638 Nerve Degeneration marker/mechanism
17136323
D009798 D009638 Ocular Hypertension therapeutic
1138682
D009846 D009638 Oliguria marker/mechanism
618599
D009901 D009638 Optic Nerve Diseases therapeutic
6213676
D010146 D009638 Pain marker/mechanism
8773445
D010243 D009638 Paralysis marker/mechanism
3370449
D010554 D009638 Personality Disorders marker/mechanism
3575346
D011183 D009638 Postoperative Complications therapeutic
10972598
D011249 D009638 Pregnancy Complications, Cardiovascular marker/mechanism
6735272
D011297 D009638 Prenatal Exposure Delayed Effects marker/mechanism
3988167
D011507 D009638 Proteinuria marker/mechanism
464098
D011605 D009638 Psychoses, Substance-Induced marker/mechanism
8878306
9205790
D029424 D009638 Pulmonary Disease, Chronic Obstructive marker/mechanism
18068611
D051437 D009638 Renal Insufficiency marker/mechanism
6735272
D012120 D009638 Respiration Disorders therapeutic
2880686
D012131 D009638 Respiratory Insufficiency therapeutic
11089775
D012164 D009638 Retinal Diseases therapeutic
6213676
D012206 D009638 Rhabdomyolysis marker/mechanism
16431110
D012640 D009638 Seizures marker/mechanism
1984432
6742791
7856916
20433896
D018805 D009638 Sepsis therapeutic
21519229
D012769 D009638 Shock marker/mechanism
therapeutic
10570779
14122464
D012770 D009638 Shock, Cardiogenic therapeutic
21037469
D012771 D009638 Shock, Hemorrhagic therapeutic
1039254
D012772 D009638 Shock, Septic therapeutic
2408258
2747604
7798451
10075057
17125115
19039826
19050641
D013035 D009638 Spasm marker/mechanism
7315949
D013226 D009638 Status Epilepticus marker/mechanism
15488322
16563474
D013274 D009638 Stomach Neoplasms therapeutic
1908657
7944421
D013345 D009638 Subarachnoid Hemorrhage marker/mechanism
2775019
D013375 D009638 Substance Withdrawal Syndrome marker/mechanism
6488684
D013610 D009638 Tachycardia marker/mechanism
therapeutic
526067
1335070
1706810
1719281
2550615
2880686
3261545
6125170
6268123
7539346
8687027
19693491
D013616 D009638 Tachycardia, Sinus marker/mechanism
therapeutic
11089775
20406625
D017180 D009638 Tachycardia, Ventricular marker/mechanism
1581859
2880726
3351156
D014511 D009638 Uremia marker/mechanism
6652879
D056987 D009638 Vasoplegia therapeutic
12830064
D018754 D009638 Ventricular Dysfunction marker/mechanism
12010770
D018487 D009638 Ventricular Dysfunction, Left marker/mechanism
1428250
2083593
7995660
D014693 D009638 Ventricular Fibrillation marker/mechanism
therapeutic
2766111
6103072
6655564