Piper obliquum

• Index
• Plant Species
• Metabolite list (25)
• Human Protein
  / Gene in interactions
• Related Diseases

Species

KNApSAcK Entry

Organism name	Piper obliquum
Genus	Piper
Family	Piperaceae
Kingdom	Plantae

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NCBI taxonomy

Entry

Linked NCBI taxonomy name	Piper obliquum
Linked NCBI taxonomy ID	425162
Linked level	species

Family

Family in NCBI taxonomy	Piperaceae
ID	16739

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy	Viridiplantae
ID	33090

Plant class

Plant class	Magnoliophyta
ID	3398

Metabolite list (25)

KNApSAcK ID	name	ChEMBL link	CTD link	# of proteins in ChEMBL interaction / related OMIM / related KEGG DISEASE	# of genes in CTD interaction / related diseases	KCF-S cluster	phytochemical cluster	figure
C00030479	Hexadecanoic acid / n-Hexadecanoic acid	CHEMBL82293	D019308	16 / 8 / 8	35 / 1	No. 184	No. 68
C00021213	Globulol / (-)-Globulol	CHEMBL2171207		1 / 2 / 3		No. 197	No. 38
C00033734	Cubenol					No. 205	No. 38
C00020066	T-Cadinol / epi-alpha-Cadinol	CHEMBL486795	C072576			No. 205	No. 38
C00020130	gamma-Muurolene / 1beta-Cadina-4,10(15)-diene					No. 283	No. 39
C00030345	gamma-Cadinene		C054278			No. 283	No. 39
C00029671	alpha-Muurolene					No. 283	No. 39
C00021423	1,5-Epoxysalvial-4(14)-ene					No. 311
C00003118	Copaene / alpha-Copaene / (-)-alpha-Copaene					No. 333	No. 38
C00003120	alpha-Cubebene					No. 333	No. 38
C00000816	beta-Pinene	CHEMBL501351	C010789			No. 476	No. 35
C00000805	alpha-Pinene	CHEMBL442565	C005451	3 / 3 / 2	0 / 1	No. 476	No. 35
C00021227	alpha-Gurjunene					No. 595	No. 38
C00029369	10-epi-gamma-Eudesmol / (-)-10-epi-gamma-Eudesmol	CHEMBL477900				No. 613	No. 38
C00021230	Aromadendrene / (+)-Aromadendrene / (+)-Aromadendr-7(15)-ene	CHEMBL509805 CHEMBL596664				No. 640
C00007242	beta-Bisabolene / l-beta-Bisabolene / (-)-beta-Bisabolene	CHEMBL444389 CHEMBL1077088 CHEMBL2001434				No. 701	No. 38
C00007453	Cyclohexane / beta-Elemene	CHEMBL448502 CHEMBL479707				No. 1400
C00012012	gamma-Elemene / (-)-gamma-Elemene					No. 1400
C00003147	Humulene / alpha-Caryophyllene / (+/-)-alpha-Humulene	CHEMBL251280	C042686			No. 1421	No. 38
C00007636	delta-Cadinene	CHEMBL445759				No. 1524	No. 39
C00000149	Spathulenol	CHEMBL518542 CHEMBL1774433	C013258			No. 1603
C00003040	p-Cymene	CHEMBL442915	C007210			No. 2172	No. 35
C00011720	Germacrene D / (-)-Germacrene D	CHEMBL105432 CHEMBL1836650				No. 2639	No. 38
C00003048	Linalyl acetate / Linaloyl acetate	CHEMBL502773	C074463	1 / 0 / 1		No. 4126	No. 34
C00030933	p-Cymen-8-ol					No. 8611

Human Protein / Gene in interactions

20 ChEMBL Protein in interactions

accession	description	class description	KNApSAcK metabolite in interactions	# of diseases (OMIM / KEGG)
P04150	Glucocorticoid receptor	NR3C1	C00003048 C00030479	0 / 1
O60603	Toll-like receptor 2	Membrane receptor	C00030479	1 / 1
P05413	Fatty acid-binding protein, heart	Other cytosolic protein	C00030479	0 / 0
P08047	Transcription factor Sp1	Unclassified protein	C00030479	0 / 0
P16473	Thyrotropin receptor	Glycohormone receptor	C00000805	3 / 2
P08183	Multidrug resistance protein 1	drug	C00030479	1 / 0
P11387	DNA topoisomerase 1	Isomerase	C00030479	0 / 0
O75496	Geminin	Unclassified protein	C00030479	0 / 0
P12104	Fatty acid-binding protein, intestinal	Other cytosolic protein	C00030479	0 / 0
O94782	Ubiquitin carboxyl-terminal hydrolase 1	Enzyme	C00030479	0 / 0
P15090	Fatty acid-binding protein, adipocyte	Other cytosolic protein	C00030479	0 / 0
P11511	Cytochrome P450 19A1	Cytochrome P450 19A1	C00030479	2 / 2
Q96RI1	Bile acid receptor	NR1H4	C00030479	0 / 0
P08581	Hepatocyte growth factor receptor	TK tyrosine-protein kinase MET subfamily	C00021213	2 / 3
P28482	Mitogen-activated protein kinase 1	Erk	C00000805	0 / 0
Q01469	Fatty acid-binding protein, epidermal	Other cytosolic protein	C00030479	0 / 0
P51449	Nuclear receptor ROR-gamma	Nuclear hormone receptor subfamily 1 group F member 3	C00000805	0 / 0
P03372	Estrogen receptor	NR3A1	C00030479	1 / 1
P10275	Androgen receptor	NR3C4	C00030479	3 / 4
Q07869	Peroxisome proliferator-activated receptor alpha	NR1C1	C00030479	0 / 0

35 Gene in CTD interactions

gene	gene name	gene description	KNApSAcK metabolite in interactions
9619	ABCG1, ABC8, WHITE1	ATP-binding cassette, sub-family G (WHITE), member 1	C00030479
207	AKT1, AKT, CWS6, PKB, PKB-ALPHA, PRKBA, RAC, RAC-ALPHA	v-akt murine thymoma viral oncogene homolog 1 (EC:2.7.11.1)	C00030479
213	ALB, PRO0883, PRO0903, PRO1341	albumin	C00030479
581	BAX, BCL2L4	BCL2-associated X protein	C00030479
596	BCL2, Bcl-2, PPP1R50	B-cell CLL/lymphoma 2	C00030479
836	CASP3, CPP32, CPP32B, SCA-1	caspase 3, apoptosis-related cysteine peptidase (EC:3.4.22.56)	C00030479
840	CASP7, CASP-7, CMH-1, ICE-LAP3, LICE2, MCH3	caspase 7, apoptosis-related cysteine peptidase (EC:3.4.22.60)	C00030479
6348	CCL3, G0S19-1, LD78ALPHA, MIP-1-alpha, MIP1A, SCYA3	chemokine (C-C motif) ligand 3	C00030479
1374	CPT1A, CPT1, CPT1-L, L-CPT1	carnitine palmitoyltransferase 1A (liver) (EC:2.3.1.21)	C00030479
1906	EDN1, ET1, HDLCQ7, PPET1	endothelin 1	C00030479
2876	GPX1, GPXD, GSHPX1	glutathione peroxidase 1 (EC:1.11.1.9)	C00030479
3034	HAL, HIS, HSTD	histidine ammonia-lyase (EC:4.3.1.3)	C00030479
57817	HAMP, HEPC, HFE2B, LEAP1, PLTR	hepcidin antimicrobial peptide	C00030479
3481	IGF2, C11orf43, IGF-II, PP9974	insulin-like growth factor 2 (somatomedin A)	C00030479
3576	IL8, CXCL8, GCP-1, GCP1, LECT, LUCT, LYNAP, MDNCF, MONAP, NAF, NAP-1, NAP1	interleukin 8	C00030479
3630	INS, IDDM2, ILPR, IRDN, MODY10	insulin	C00030479
1432	MAPK14, CSBP, CSBP1, CSBP2, CSPB1, EXIP, Mxi2, PRKM14, PRKM15, RK, SAPK2A, p38, p38ALPHA	mitogen-activated protein kinase 14 (EC:2.7.11.24)	C00030479
5599	MAPK8, JNK, JNK-46, JNK1, JNK1A2, JNK21B1/2, PRKM8, SAPK1, SAPK1c	mitogen-activated protein kinase 8 (EC:2.7.11.24)	C00030479
5601	MAPK9, JNK-55, JNK2, JNK2A, JNK2ALPHA, JNK2B, JNK2BETA, PRKM9, SAPK, SAPK1a, p54a, p54aSAPK	mitogen-activated protein kinase 9 (EC:2.7.11.24)	C00030479
4493	MT1E, MT1, MTD	metallothionein 1E	C00030479
4494	MT1F, MT1	metallothionein 1F	C00030479
4496	MT1H, MT-0, MT-1H, MT-IH, MT1	metallothionein 1H	C00030479
4501	MT1X, MT-1l, MT1	metallothionein 1X	C00030479
4502	MT2A, MT2	metallothionein 2A	C00030479
4843	NOS2, HEP-NOS, INOS, NOS, NOS2A	nitric oxide synthase 2, inducible (EC:1.14.13.39)	C00030479
3651	PDX1, GSF, IDX-1, IPF1, IUF1, MODY4, PDX-1, STF-1	pancreatic and duodenal homeobox 1	C00030479
5465	PPARA, NR1C1, PPAR, PPARalpha, hPPAR	peroxisome proliferator-activated receptor alpha	C00030479
10891	PPARGC1A, LEM6, PGC-1(alpha), PGC-1v, PGC1, PGC1A, PPARGC1	peroxisome proliferator-activated receptor gamma, coactivator 1 alpha	C00030479
29893	PSMC3IP, GT198, HOP2, HUMGT198A, ODG3, TBPIP	PSMC3 interacting protein	C00030479
5970	RELA, NFKB3, p65	v-rel avian reticuloendotheliosis viral oncogene homolog A	C00030479
5054	SERPINE1, PAI, PAI-1, PAI1, PLANH1	serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1	C00030479
6647	SOD1, ALS, ALS1, IPOA, SOD, hSod1, homodimer	superoxide dismutase 1, soluble (EC:1.15.1.1)	C00030479
23216	TBC1D1, TBC, TBC1	TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1	C00030479
7124	TNF, DIF, TNF-alpha, TNFA, TNFSF2	tumor necrosis factor	C00030479
7351	UCP2, BMIQ4, SLC25A8, UCPH	uncoupling protein 2 (mitochondrial, proton carrier)	C00030479

Related Diseases

Diseases related to proteins in ChEMBL interactions

Diseases related to CTD interactions