Species

KNApSAcK Entry

Organism name Galanthus elwesii
Genus Galanthus
Family Amaryllidaceae
Kingdom Plantae

NCBI taxonomy

Entry

Linked NCBI taxonomy name Galanthus elwesii
Linked NCBI taxonomy ID 82232
Linked level species

Family

Family in NCBI taxonomy Amaryllidaceae
ID 4668

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Viridiplantae
ID 33090

Plant class

Plant class Liliopsida
ID 4447

Metabolite list (15)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE
# of genes in
CTD interaction
/ related diseases
KCF-S
cluster
phytochemical
cluster
figure
C00001571 External link 512 Haemanthamine
CHEMBL401114
CHEMBL516991
CHEMBL1172810
CHEMBL1221865
CHEMBL1551610
CHEMBL1995397
C462104
5 / 6 / 3 No. 103 No. 4
C00024384 External link 512 Crinine
/ Crinidine
CHEMBL469648
CHEMBL1221864
CHEMBL1971343
3 / 1 / 0 No. 103 No. 4
C00024371 External link 512 Buphanisine
CHEMBL512945
No. 103 No. 4
C00024438 External link 512 Tazettine
/ (+)-Tazettine
CHEMBL457605
CHEMBL1720510
CHEMBL1997188
C011361
6 / 1 / 0 No. 103 No. 4
C00024385 External link 512 Crinine
No. 253 No. 4
C00024414 External link 512 Norgalantamine
/ N-Norgalanthamine
/ N-Demethylgalanthamine
CHEMBL1385
1 / 1 / 0 No. 580 No. 4
C00027607 External link 512 Norgalantamine
/ N-Norgalanthamine
/ N-Demethylgalanthamine
/ (-)-N-Demethylgalanthamine
CHEMBL1385
1 / 1 / 0 No. 580 No. 4
C00028682 External link 512 N-Formylgalanthamine
No. 580 No. 4
C00001578 External link 512 Narwedine
CHEMBL2146604
C069154
No. 580 No. 4
C00028725 External link 512 Norlycoramine
No. 580 No. 4
C00024408 External link 512 Maritidine
No. 780 No. 4
C00024419 External link 512 O-Methylleucotamine
/ (-)-O-Methylleucotamine
No. 1092
C00028291 External link 512 Galwesine
No. 1739
C00028290 External link 512 Galasine
No. 1739
C00029148 External link 512 Trispheridine
/ Trisphaeridine
CHEMBL511443
C462033
1 / 0 / 0 No. 2882 No. 7

Human Protein / Gene in interactions

12 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
P22303 Acetylcholinesterase Hydrolase C00001571 C00024384 C00024414 C00024438 C00027607 1 / 0
P11387 DNA topoisomerase 1 Isomerase C00024384 C00029148 0 / 0
P28482 Mitogen-activated protein kinase 1 Erk C00001571 0 / 0
O75496 Geminin Unclassified protein C00024438 0 / 0
P43220 Glucagon-like peptide 1 receptor Glucagon-like peptide receptor C00024438 0 / 0
P83916 Chromobox protein homolog 1 Unclassified protein C00024438 0 / 0
P11388 DNA topoisomerase 2-alpha Isomerase C00024384 0 / 0
Q96QE3 ATPase family AAA domain-containing protein 5 Unclassified protein C00024438 0 / 0
Q16637 Survival motor neuron protein Unclassified protein C00001571 4 / 1
P08684 Cytochrome P450 3A4 Cytochrome P450 3A4 C00001571 0 / 1
Q9UNA4 DNA polymerase iota Enzyme C00024438 0 / 0
Q9NUW8 Tyrosyl-DNA phosphodiesterase 1 Enzyme C00001571 1 / 1

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (6)

OMIM preferred title UniProt
#253300 Spinal muscular atrophy, type i; sma1 Q16637
#253550 Spinal muscular atrophy, type ii; sma2 Q16637
#253400 Spinal muscular atrophy, type iii; sma3 Q16637
#271150 Spinal muscular atrophy, type iv; sma4 Q16637
#607250 Spinocerebellar ataxia, autosomal recessive, with axonal neuropathy; scan1 Q9NUW8
#112100 Yt blood group antigen P22303

KEGG DISEASE (3)

KEGG name UniProt
H00036 Osteosarcoma P08684 (marker)
H00455 Spinal muscular atrophy (SMA) Q16637 (related)
H00063 Spinocerebellar ataxia (SCA) Q9NUW8 (related)