PCIDB

Thalictrum triternatum

Species

KNApSAcK Entry

Organism name Thalictrum triternatum
Genus Thalictrum
Family Ranunculaceae
Kingdom Plantae

NCBI taxonomy

Entry

Linked NCBI taxonomy name Thalictrum
Linked NCBI taxonomy ID 46968
Linked level genus

Family

Family in NCBI taxonomy Ranunculaceae
ID 3440

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Viridiplantae
ID 33090

Plant class

Plant class eudicotyledons
ID 71240

Metabolite list (5)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE 		# of genes in
CTD interaction
/ related diseases 		KCF-S
cluster 		phytochemical
cluster 		figure
C00027494 External link 512 Thalmine
No. 10 No. 4
C00027490 External link 512 Thalfine
No. 10 No. 4
C00001861 External link 512 Glaucine
/ S-(+)-Glaucine
/ O,O-Dimethylisoboldine
CHEMBL36536
CHEMBL228082
14 / 8 / 6 No. 20 No. 4
C00001906 External link 512 Fumarin
/ Biflorine
/ Protopine
/ Fumarine
/ Corydinine
CHEMBL453019
C009093
5 / 5 / 4 2 / 0 No. 820 No. 4
C00001799 External link 512 Thalictrimine
/ Allocryptopine
/ alpha-Fagarine
/ beta-Homochelidonine
/ alpha-Allocryptopine
CHEMBL520043
C109505
3 / 2 / 3 2 / 0 No. 820 No. 4

Human Protein / Gene in interactions

20 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
Q9UNA4 DNA polymerase iota Enzyme C00001799 C00001861 0 / 0
B2RXH2 Lysine-specific demethylase 4E Enzyme C00001861 C00001906 0 / 0
Q03164 Histone-lysine N-methyltransferase 2A Enzyme C00001799 1 / 2
P42574 Caspase-3 C14 C00001861 0 / 0
Q9NR56 Muscleblind-like protein 1 Unclassified protein C00001861 1 / 0
Q9BQF6 Sentrin-specific protease 7 Enzyme C00001861 0 / 0
Q9GZR1 Sentrin-specific protease 6 Enzyme C00001861 0 / 0
Q14761 Protein tyrosine phosphatase receptor type C-associated protein Enzyme C00001861 0 / 0
P00352 Retinal dehydrogenase 1 Enzyme C00001861 0 / 0
O75496 Geminin Unclassified protein C00001861 0 / 0
P16473 Thyrotropin receptor Glycohormone receptor C00001906 3 / 2
Q99714 3-hydroxyacyl-CoA dehydrogenase type-2 Enzyme C00001861 3 / 3
Q96QE3 ATPase family AAA domain-containing protein 5 Unclassified protein C00001861 0 / 0
P33261 Cytochrome P450 2C19 Cytochrome P450 2C19 C00001906 1 / 1
P08684 Cytochrome P450 3A4 Cytochrome P450 3A4 C00001906 0 / 1
P10635 Cytochrome P450 2D6 Cytochrome P450 2D6 C00001906 1 / 0
P10636 Microtubule-associated protein tau Unclassified protein C00001861 4 / 3
Q96LD8 Sentrin-specific protease 8 Enzyme C00001861 0 / 0
P43351 DNA repair protein RAD52 homolog Unclassified protein C00001861 0 / 0
Q13148 TAR DNA-binding protein 43 Unclassified protein C00001799 1 / 1

2 Gene in CTD interactions

gene gene name gene description KNApSAcK metabolite in interactions
1543 CYP1A1, AHH, AHRR, CP11, CYP1, P1-450, P450-C, P450DX cytochrome P450, family 1, subfamily A, polypeptide 1 (EC:1.14.14.1) C00001799 C00001906
1544 CYP1A2, CP12, P3-450, P450(PA) cytochrome P450, family 1, subfamily A, polypeptide 2 (EC:1.14.14.1) C00001799 C00001906

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (15)

OMIM preferred title UniProt
#300438 17-beta-hydroxysteroid dehydrogenase x deficiency Q99714
#612069 Amyotrophic lateral sclerosis 10, with or without frontotemporal dementia; als10 Q13148
#609535 Drug metabolism, poor, cyp2c19-related P33261
#608902 Drug metabolism, poor, cyp2d6-related P10635
#600274 Frontotemporal dementia; ftd P10636
#605130 Hairy elbows, short stature, facial dysmorphism, and developmental delay Q03164
#603373 Hyperthyroidism, familial gestational P16473
#609152 Hyperthyroidism, nonautoimmune P16473
#275200 Hypothyroidism, congenital, nongoitrous, 1; chng1 P16473
#300705 Mental retardation, x-linked 17; mrx17 Q99714
#300220 Mental retardation, x-linked, syndromic 10; mrxs10 Q99714
#160900 Myotonic dystrophy 1; dm1 Q9NR56
#260540 Parkinson-dementia syndrome P10636
#172700 Pick disease of brain P10636
#601104 Supranuclear palsy, progressive, 1; psnp1 P10636

KEGG DISEASE (12)

KEGG name UniProt
H00036 Osteosarcoma P08684 (marker)
H00058 Amyotrophic lateral sclerosis (ALS) P10636 (related)
Q13148 (related)
H00077 Progressive supranuclear palsy (PSP) P10636 (related)
H00078 Frontotemporal lobar degeneration (FTLD) P10636 (related)
H00250 Congenital nongoitrous hypothyroidism (CHNG) P16473 (related)
H01269 Congenital hyperthyroidism P16473 (related)
H01171 Poor drug metabolism (PM) P33261 (related)
H00001 Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) Q03164 (related)
Q03164 (marker)
H00002 Acute lymphoblastic leukemia (ALL) (precursor T lymphoblastic leukemia) Q03164 (related)
H00480 Non-syndromic X-linked mental retardation Q99714 (related)
H00658 Syndromic X-linked mental retardation Q99714 (related)
H00925 2-Methyl-3-hydroxybutyryl-CoA dehydrogenase (MHBD) deficiency Q99714 (related)