| Organism name | Fumaria officinalis | 
|---|---|
| Genus | Fumaria | 
| Family | Fumariaceae | 
| Kingdom | Plantae | 
| Linked NCBI taxonomy name | Fumaria officinalis | 
|---|---|
| Linked NCBI taxonomy ID | 200993 | 
| Linked level | species | 
| Family in NCBI taxonomy | Papaveraceae | 
|---|---|
| ID | 3465 | 
| Kingdom (Superkingdom) in NCBI taxonomy | Viridiplantae | 
|---|---|
| ID | 33090 | 
| Plant class | eudicotyledons | 
|---|---|
| ID | 71240 | 
| KNApSAcK ID | name | ChEMBL link | CTD link | # of proteins in ChEMBL interaction / related OMIM / related KEGG DISEASE | # of genes in CTD interaction / related diseases | KCF-S cluster | phytochemical cluster | figure | 
|---|---|---|---|---|---|---|---|---|
| C00001824   | Bulbocapnine / d-Bulbocapnine | CHEMBL157912 | C083807 | 0 / 1 | No. 20 | No. 4 |   | |
| C00026095   | Stylopine / (-)-Stylopine / l-Tetrahydrocoptisine / (-)-Tetrahydrocoptisine | CHEMBL1922602 | No. 37 | No. 4 |   | |||
| C00026144   | Sinactine / Tetrahydroepiberberine | No. 37 | No. 4 |   | ||||
| C00027159   | Depiline / Palmatine / Berbericinine / O,O-Dimethyldemethyleneberberine | CHEMBL206106 | C005413 | 8 / 13 / 13 | 8 / 0 | No. 155 | No. 4 |   | 
| C00024668   | YHL II / Coptisine | CHEMBL362071 | C034384 | No. 155 | No. 4 |   | ||
| C00001917   | Sanguinarine / Pseudochelerythrine | CHEMBL417799 | C005705 | 55 / 55 / 77 | 23 / 6 | No. 254 | No. 4 |   | 
| C00001900   | Parfumine / d-Parfumine / (+)-Parfumine | CHEMBL1968957 | No. 512 | No. 4 |   | |||
| C00001859   | Fumaricine | No. 512 | No. 4 |   | ||||
| C00027368   | Fumariline | C049095 | No. 512 | No. 4 |   | |||
| C00027369   | Fumarophycine / O-Acetylfumaritine | No. 512 | No. 4 |   | ||||
| C00027452   | O-Acetylfumaricine / Fumaricine acetate / O-Methylfumarophycine / (-)-O-Methylfumarophycine | No. 512 | No. 4 |   | ||||
| C00001906   | Fumarin / Biflorine / Protopine / Fumarine / Corydinine | CHEMBL453019 | C009093 | 5 / 5 / 4 | 2 / 0 | No. 820 | No. 4 |   | 
| C00027268   | Adlumiceine | No. 2202 | No. 4 |   | ||||
| C00027269   | Adlumidiceine | No. 2202 | No. 4 |   | 
| accession | description | class description | KNApSAcK metabolite in interactions | # of diseases (OMIM / KEGG) | 
|---|---|---|---|---|
| P10635 | Cytochrome P450 2D6 | Cytochrome P450 2D6 | C00001906 C00001917 C00027159 | 1 / 0 | 
| P33261 | Cytochrome P450 2C19 | Cytochrome P450 2C19 | C00001906 C00001917 C00027159 | 1 / 1 | 
| P08684 | Cytochrome P450 3A4 | Cytochrome P450 3A4 | C00001906 C00001917 C00027159 | 0 / 1 | 
| O94782 | Ubiquitin carboxyl-terminal hydrolase 1 | Enzyme | C00001917 C00027159 | 0 / 0 | 
| P05177 | Cytochrome P450 1A2 | Cytochrome P450 1A2 | C00001917 C00027159 | 0 / 0 | 
| B2RXH2 | Lysine-specific demethylase 4E | Enzyme | C00001906 C00001917 | 0 / 0 | 
| Q16665 | Hypoxia-inducible factor 1-alpha | Transcription Factor | C00001917 C00027159 | 0 / 0 | 
| P11712 | Cytochrome P450 2C9 | Cytochrome P450 2C9 | C00001917 C00027159 | 0 / 1 | 
| P16473 | Thyrotropin receptor | Glycohormone receptor | C00001906 C00001917 | 3 / 2 | 
| P02545 | Prelamin-A/C | Unclassified protein | C00001917 C00027159 | 11 / 10 | 
| Q9HC16 | DNA dC->dU-editing enzyme APOBEC-3G | Enzyme | C00001917 | 0 / 0 | 
| P21728 | D(1A) dopamine receptor | Dopamine receptor | C00001917 | 0 / 0 | 
| O14924 | Regulator of G-protein signaling 12 | Unclassified protein | C00001917 | 0 / 0 | 
| P37840 | Alpha-synuclein | Unclassified protein | C00001917 | 4 / 2 | 
| P14618 | Pyruvate kinase PKM | Enzyme | C00001917 | 0 / 0 | 
| P49798 | Regulator of G-protein signaling 4 | Unclassified protein | C00001917 | 2 / 0 | 
| P11473 | Vitamin D3 receptor | NR1I1 | C00001917 | 2 / 3 | 
| O15296 | Arachidonate 15-lipoxygenase B | Enzyme | C00001917 | 0 / 0 | 
| P00352 | Retinal dehydrogenase 1 | Enzyme | C00001917 | 0 / 0 | 
| Q99700 | Ataxin-2 | Unclassified protein | C00001917 | 1 / 1 | 
| P39748 | Flap endonuclease 1 | Enzyme | C00001917 | 0 / 0 | 
| Q92830 | Histone acetyltransferase KAT2A | Enzyme | C00001917 | 0 / 0 | 
| P42858 | Huntingtin | Unclassified protein | C00001917 | 1 / 1 | 
| P84022 | Mothers against decapentaplegic homolog 3 | Unclassified protein | C00001917 | 2 / 0 | 
| P51151 | Ras-related protein Rab-9A | Unclassified protein | C00001917 | 0 / 0 | 
| P42226 | Signal transducer and activator of transcription 6 | Unclassified protein | C00001917 | 0 / 0 | 
| P83916 | Chromobox protein homolog 1 | Unclassified protein | C00001917 | 0 / 0 | 
| O75604 | Ubiquitin carboxyl-terminal hydrolase 2 | Enzyme | C00001917 | 0 / 0 | 
| Q9NPD5 | Solute carrier organic anion transporter family member 1B3 | Electrochemical transporter | C00001917 | 1 / 0 | 
| P11021 | 78 kDa glucose-regulated protein | Unclassified protein | C00001917 | 0 / 0 | 
| O94956 | Solute carrier organic anion transporter family member 2B1 | Unclassified protein | C00001917 | 0 / 0 | 
| Q99816 | Tumor susceptibility gene 101 protein | Unclassified protein | C00001917 | 0 / 0 | 
| P18054 | Arachidonate 12-lipoxygenase, 12S-type | Enzyme | C00001917 | 2 / 0 | 
| P28482 | Mitogen-activated protein kinase 1 | Erk | C00001917 | 0 / 0 | 
| Q9Y6L6 | Solute carrier organic anion transporter family member 1B1 | Electrochemical transporter | C00001917 | 1 / 0 | 
| Q99714 | 3-hydroxyacyl-CoA dehydrogenase type-2 | Enzyme | C00001917 | 3 / 3 | 
| P15428 | 15-hydroxyprostaglandin dehydrogenase [NAD(+)] | Enzyme | C00001917 | 2 / 2 | 
| O15118 | Niemann-Pick C1 protein | Unclassified protein | C00001917 | 1 / 1 | 
| Q96QE3 | ATPase family AAA domain-containing protein 5 | Unclassified protein | C00001917 | 0 / 0 | 
| P19838 | Nuclear factor NF-kappa-B p105 subunit | Transcription Factor | C00001917 | 0 / 0 | 
| P16050 | Arachidonate 15-lipoxygenase | Enzyme | C00001917 | 0 / 0 | 
| Q16637 | Survival motor neuron protein | Unclassified protein | C00001917 | 4 / 1 | 
| P04637 | Cellular tumor antigen p53 | Transcription Factor | C00001917 | 7 / 37 | 
| Q9UNA4 | DNA polymerase iota | Enzyme | C00001917 | 0 / 0 | 
| P10636 | Microtubule-associated protein tau | Unclassified protein | C00001917 | 4 / 3 | 
| Q16236 | Nuclear factor erythroid 2-related factor 2 | Unclassified protein | C00001917 | 0 / 0 | 
| Q92934 | Bcl2 antagonist of cell death | Other cytosolic protein | C00001917 | 0 / 0 | 
| P42345 | Serine/threonine-protein kinase mTOR | Enzyme | C00001917 | 0 / 0 | 
| P40225 | Thrombopoietin | Unclassified protein | C00001917 | 1 / 1 | 
| Q96KQ7 | Histone-lysine N-methyltransferase EHMT2 | Enzyme | C00001917 | 0 / 0 | 
| O00255 | Menin | Unclassified protein | C00001917 | 2 / 5 | 
| Q03164 | Histone-lysine N-methyltransferase 2A | Enzyme | C00001917 | 1 / 2 | 
| Q13951 | Core-binding factor subunit beta | Unclassified protein | C00001917 | 0 / 1 | 
| Q01196 | Runt-related transcription factor 1 | Unclassified protein | C00001917 | 1 / 4 | 
| O94925 | Glutaminase kidney isoform, mitochondrial | Enzyme | C00001917 | 0 / 0 | 
| gene | gene name | gene description | KNApSAcK metabolite in interactions | 
|---|---|---|---|
| 1543 | CYP1A1, AHH, AHRR, CP11, CYP1, P1-450, P450-C, P450DX | cytochrome P450, family 1, subfamily A, polypeptide 1 (EC:1.14.14.1) | C00001906
                          C00001917 | 
| 1365 | CLDN3, C7orf1, CPE-R2, CPETR2, HRVP1, RVP1 | claudin 3 | C00001917 | 
| 6348 | CCL3, G0S19-1, LD78ALPHA, MIP-1-alpha, MIP1A, SCYA3 | chemokine (C-C motif) ligand 3 | C00027159 | 
| 6351 | CCL4, ACT2, AT744.1, G-26, HC21, LAG-1, LAG1, MIP-1-beta, MIP1B, MIP1B1, SCYA2, SCYA4 | chemokine (C-C motif) ligand 4 | C00027159 | 
| 6352 | CCL5, D17S136E, RANTES, SCYA5, SIS-delta, SISd, TCP228, eoCP | chemokine (C-C motif) ligand 5 | C00027159 | 
| 3570 | IL6R, CD126, IL-6R-1, IL-6RA, IL6Q, IL6RA, IL6RQ, gp80 | interleukin 6 receptor | C00027159 | 
| 3576 | IL8, CXCL8, GCP-1, GCP1, LECT, LUCT, LYNAP, MDNCF, MONAP, NAF, NAP-1, NAP1 | interleukin 8 | C00027159 | 
| 7422 | VEGFA, MVCD1, VEGF, VPF | vascular endothelial growth factor A | C00027159 | 
| 196 | AHR, bHLHe76 | aryl hydrocarbon receptor | C00001917 | 
| 405 | ARNT, HIF-1-beta, HIF-1beta, HIF1-beta, HIF1B, HIF1BETA, TANGO, bHLHe2 | aryl hydrocarbon receptor nuclear translocator | C00001917 | 
| 581 | BAX, BCL2L4 | BCL2-associated X protein | C00001917 | 
| 596 | BCL2, Bcl-2, PPP1R50 | B-cell CLL/lymphoma 2 | C00001917 | 
| 836 | CASP3, CPP32, CPP32B, SCA-1 | caspase 3, apoptosis-related cysteine peptidase (EC:3.4.22.56) | C00001917 | 
| 841 | CASP8, ALPS2B, CAP4, Casp-8, FLICE, MACH, MCH5 | caspase 8, apoptosis-related cysteine peptidase (EC:3.4.22.61) | C00001917 | 
| 842 | CASP9, APAF-3, APAF3, ICE-LAP6, MCH6, PPP1R56 | caspase 9, apoptosis-related cysteine peptidase (EC:3.4.22.62) | C00001917 | 
| 9075 | CLDN2 | claudin 2 | C00001917 | 
| 6347 | CCL2, GDCF-2, HC11, HSMCR30, MCAF, MCP-1, MCP1, SCYA2, SMC-CF | chemokine (C-C motif) ligand 2 | C00027159 | 
| 1364 | CLDN4, CPE-R, CPER, CPETR, CPETR1, WBSCR8, hCPE-R | claudin 4 | C00001917 | 
| 7122 | CLDN5, AWAL, BEC1, CPETRL1, TMVCF | claudin 5 | C00001917 | 
| 332 | BIRC5, API4, EPR-1 | baculoviral IAP repeat containing 5 | C00027159 | 
| 1545 | CYP1B1, CP1B, CYPIB1, GLC3A, P4501B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 (EC:1.14.14.1) | C00001917 | 
| 2950 | GSTP1, DFN7, FAEES3, GST3, GSTP, PI | glutathione S-transferase pi 1 (EC:2.5.1.18) | C00001917 | 
| 5594 | MAPK1, ERK, ERK2, ERT1, MAPK2, P42MAPK, PRKM1, PRKM2, p38, p40, p41, p41mapk | mitogen-activated protein kinase 1 (EC:2.7.11.24) | C00001917 | 
| 5595 | MAPK3, ERK-1, ERK1, ERT2, HS44KDAP, HUMKER1A, P44ERK1, P44MAPK, PRKM3, p44-ERK1, p44-MAPK | mitogen-activated protein kinase 3 (EC:2.7.11.24) | C00001917 | 
| 5599 | MAPK8, JNK, JNK-46, JNK1, JNK1A2, JNK21B1/2, PRKM8, SAPK1, SAPK1c | mitogen-activated protein kinase 8 (EC:2.7.11.24) | C00001917 | 
| 5601 | MAPK9, JNK-55, JNK2, JNK2A, JNK2ALPHA, JNK2B, JNK2BETA, PRKM9, SAPK, SAPK1a, p54a, p54aSAPK | mitogen-activated protein kinase 9 (EC:2.7.11.24) | C00001917 | 
| 4313 | MMP2, CLG4, CLG4A, MMP-II, MONA, TBE-1 | matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase) (EC:3.4.24.24) | C00001917 | 
| 4318 | MMP9, CLG4B, GELB, MANDP2, MMP-9 | matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase) (EC:3.4.24.35) | C00001917 | 
| 1728 | NQO1, DHQU, DIA4, DTD, NMOR1, NMORI, QR1 | NAD(P)H dehydrogenase, quinone 1 (EC:1.6.5.2) | C00001917 | 
| 6615 | SNAI1, SLUGH2, SNA, SNAH, SNAIL, SNAIL1, dJ710H13.1 | snail family zinc finger 1 | C00001917 | 
| 7124 | TNF, DIF, TNF-alpha, TNFA, TNFSF2 | tumor necrosis factor | C00001917 | 
| 1544 | CYP1A2, CP12, P3-450, P450(PA) | cytochrome P450, family 1, subfamily A, polypeptide 2 (EC:1.14.14.1) | C00001906 | 
| OMIM | preferred title | UniProt | 
|---|---|---|
| #300438 | 17-beta-hydroxysteroid dehydrogenase x deficiency | Q99714 | 
| #202300 | Adrenocortical carcinoma, hereditary; adcc | P04637 | 
| #614740 | Basal cell carcinoma, susceptibility to, 7; bcc7 | P04637 | 
| #115200 | Cardiomyopathy, dilated, 1a; cmd1a | P02545 | 
| #212112 | Cardiomyopathy, dilated, with hypergonadotropic hypogonadism | P02545 | 
| #605588 | Charcot-marie-tooth disease, axonal, type 2b1; cmt2b1 | P02545 | 
| #114500 | Colorectal cancer; crc | P18054 P84022 | 
| #127750 | Dementia, lewy body; dlb | P37840 | 
| #119900 | Digital clubbing, isolated congenital | P15428 | 
| #609535 | Drug metabolism, poor, cyp2c19-related | P33261 | 
| #608902 | Drug metabolism, poor, cyp2d6-related | P10635 | 
| #181350 | Emery-dreifuss muscular dystrophy 2, autosomal dominant; edmd2 | P02545 | 
| #133239 | Esophageal cancer | P04637 P18054 | 
| #600274 | Frontotemporal dementia; ftd | P10636 | 
| #605130 | Hairy elbows, short stature, facial dysmorphism, and developmental delay | Q03164 | 
| #610140 | Heart-hand syndrome, slovenian type | P02545 | 
| #143100 | Huntington disease; hd | P42858 | 
| #176670 | Hutchinson-gilford progeria syndrome; hgps | P02545 | 
| #237450 | Hyperbilirubinemia, rotor type; hblrr | Q9NPD5 Q9Y6L6 | 
| #145000 | Hyperparathyroidism 1; hrpt1 | O00255 | 
| #603373 | Hyperthyroidism, familial gestational | P16473 | 
| #609152 | Hyperthyroidism, nonautoimmune | P16473 | 
| #259100 | Hypertrophic osteoarthropathy, primary, autosomal recessive, 1; phoar1 | P15428 | 
| #275200 | Hypothyroidism, congenital, nongoitrous, 1; chng1 | P16473 | 
| #151623 | Li-fraumeni syndrome 1; lfs1 | P04637 | 
| #151660 | Lipodystrophy, familial partial, type 2; fpld2 | P02545 | 
| #613795 | Loeys-dietz syndrome, type 3; lds3 | P84022 | 
| #211980 | Lung cancer | P04637 | 
| #248370 | Mandibuloacral dysplasia with type a lipodystrophy; mada | P02545 | 
| #300705 | Mental retardation, x-linked 17; mrx17 | Q99714 | 
| #300220 | Mental retardation, x-linked, syndromic 10; mrxs10 | Q99714 | 
| #131100 | Multiple endocrine neoplasia, type i; men1 | O00255 | 
| #613205 | Muscular dystrophy, congenital, lmna-related | P02545 | 
| #159001 | Muscular dystrophy, limb-girdle, type 1b; lgmd1b | P02545 | 
| #607948 | Mycobacterium tuberculosis, susceptibility to | P11473 | 
| #257220 | Niemann-pick disease, type c1; npc1 | O15118 | 
| #260500 | Papilloma of choroid plexus; cpp | P04637 | 
| #168601 | Parkinson disease 1, autosomal dominant; park1 | P37840 | 
| #605543 | Parkinson disease 4, autosomal dominant; park4 | P37840 | 
| #168600 | Parkinson disease, late-onset; pd | P37840 | 
| #260540 | Parkinson-dementia syndrome | P10636 | 
| #172700 | Pick disease of brain | P10636 | 
| #601399 | Platelet disorder, familial, with associated myeloid malignancy | Q01196 | 
| #275210 | Restrictive dermopathy, lethal | P02545 | 
| #604906 | Schizophrenia 9; sczd9 | P49798 | 
| #181500 | Schizophrenia; sczd | P49798 | 
| #253300 | Spinal muscular atrophy, type i; sma1 | Q16637 | 
| #253550 | Spinal muscular atrophy, type ii; sma2 | Q16637 | 
| #253400 | Spinal muscular atrophy, type iii; sma3 | Q16637 | 
| #271150 | Spinal muscular atrophy, type iv; sma4 | Q16637 | 
| #183090 | Spinocerebellar ataxia 2; sca2 | Q99700 | 
| #275355 | Squamous cell carcinoma, head and neck; hnscc | P04637 | 
| #601104 | Supranuclear palsy, progressive, 1; psnp1 | P10636 | 
| #187950 | Thrombocythemia 1; thcyt1 | P40225 | 
| #277440 | Vitamin d-dependent rickets, type 2a; vddr2a | P11473 | 
| KEGG | name | UniProt | 
|---|---|---|
| H00033 | Adrenal carcinoma | O00255
                            (related) P04637 (related) | 
| H00034 | Carcinoid | O00255
                            (related) | 
| H00045 | Malignant islet cell carcinoma | O00255
                            (related) | 
| H00246 | Primary hyperparathyroidism | O00255
                            (related) | 
| H01102 | Pituitary adenomas | O00255
                            (related) | 
| H00136 | Niemann-Pick disease type C (NPC) | O15118
                            (related) | 
| H00264 | Charcot-Marie-Tooth disease (CMT) | P02545
                            (related) | 
| H00294 | Dilated cardiomyopathy (DCM) | P02545
                            (related) | 
| H00420 | Familial partial lipodystrophy (FPL) | P02545
                            (related) | 
| H00563 | Emery-Dreifuss muscular dystrophy | P02545
                            (related) | 
| H00590 | Congenital muscular dystrophies (CMD/MDC) | P02545
                            (related) | 
| H00593 | Limb-girdle muscular dystrophy (LGMD) | P02545
                            (related) | 
| H00601 | Hutchinson-Gilford progeria syndrome | P02545
                            (related) | 
| H00663 | Restrictive dermopathy | P02545
                            (related) | 
| H00665 | Mandibuloacral dysplasia | P02545
                            (related) | 
| H01216 | Left ventricular noncompaction (LVNC) | P02545
                            (related) | 
| H00004 | Chronic myeloid leukemia (CML) | P04637
                            (related) Q01196 (related) | 
| H00005 | Chronic lymphocytic leukemia (CLL) | P04637
                            (related) | 
| H00006 | Hairy-cell leukemia | P04637
                            (related) | 
| H00008 | Burkitt lymphoma | P04637
                            (related) | 
| H00009 | Adult T-cell leukemia | P04637
                            (related) | 
| H00010 | Multiple myeloma | P04637
                            (related) | 
| H00013 | Small cell lung cancer | P04637
                            (related) | 
| H00014 | Non-small cell lung cancer | P04637
                            (related) | 
| H00015 | Malignant pleural mesothelioma | P04637
                            (related) | 
| H00016 | Oral cancer | P04637
                            (related) P04637 (marker) | 
| H00017 | Esophageal cancer | P04637
                            (related) P04637 (marker) | 
| H00018 | Gastric cancer | P04637
                            (related) | 
| H00019 | Pancreatic cancer | P04637
                            (related) P04637 (marker) | 
| H00020 | Colorectal cancer | P04637
                            (related) P04637 (marker) | 
| H00022 | Bladder cancer | P04637
                            (related) | 
| H00025 | Penile cancer | P04637
                            (related) P04637 (marker) | 
| H00026 | Endometrial Cancer | P04637
                            (related) | 
| H00027 | Ovarian cancer | P04637
                            (related) | 
| H00028 | Choriocarcinoma | P04637
                            (related) | 
| H00029 | Vulvar cancer | P04637
                            (related) | 
| H00031 | Breast cancer | P04637
                            (related) | 
| H00032 | Thyroid cancer | P04637
                            (related) | 
| H00036 | Osteosarcoma | P04637
                            (related) P08684 (marker) | 
| H00038 | Malignant melanoma | P04637
                            (related) | 
| H00039 | Basal cell carcinoma | P04637
                            (related) | 
| H00040 | Squamous cell carcinoma | P04637
                            (related) | 
| H00041 | Kaposi's sarcoma | P04637
                            (related) | 
| H00042 | Glioma | P04637
                            (related) P04637 (marker) | 
| H00044 | Cancer of the anal canal | P04637
                            (related) | 
| H00046 | Cholangiocarcinoma | P04637
                            (related) | 
| H00047 | Gallbladder cancer | P04637
                            (related) | 
| H00048 | Hepatocellular carcinoma | P04637
                            (related) | 
| H00055 | Laryngeal cancer | P04637
                            (related) P04637 (marker) | 
| H00881 | Li-Fraumeni syndrome | P04637
                            (related) | 
| H01007 | Choroid plexus papilloma | P04637
                            (related) | 
| H00021 | Renal cell carcinoma | P04637
                            (marker) | 
| H00058 | Amyotrophic lateral sclerosis (ALS) | P10636
                            (related) | 
| H00077 | Progressive supranuclear palsy (PSP) | P10636
                            (related) | 
| H00078 | Frontotemporal lobar degeneration (FTLD) | P10636
                            (related) | 
| H00342 | Tuberculosis | P11473
                            (related) | 
| H00784 | Localized autosomal recessive hypotrichosis | P11473
                            (related) | 
| H01143 | Vitamin D-dependent rickets | P11473
                            (related) | 
| H01205 | Coumarin resistance | P11712
                            (related) | 
| H00457 | Primary hypertrophic osteoarthropathy (PHO) | P15428
                            (related) | 
| H01246 | Isolated congenital nail clubbing (ICNC) | P15428
                            (related) | 
| H00250 | Congenital nongoitrous hypothyroidism (CHNG) | P16473
                            (related) | 
| H01269 | Congenital hyperthyroidism | P16473
                            (related) | 
| H01171 | Poor drug metabolism (PM) | P33261
                            (related) | 
| H00057 | Parkinson's disease (PD) | P37840
                            (related) | 
| H00066 | Lewy body dementia (LBD) | P37840
                            (related) | 
| H00227 | Congenital amegakaryocytic thrombocytopenia (CAMT) | P40225
                            (marker) | 
| H00059 | Huntington's disease (HD) | P42858
                            (related) | 
| H00001 | Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) | Q01196
                            (related) Q01196 (marker) Q03164 (related) Q03164 (marker) | 
| H00003 | Acute myeloid leukemia (AML) | Q01196
                            (related) Q01196 (marker) Q13951 (marker) | 
| H00978 | Thrombocytopenia (THC) | Q01196
                            (related) | 
| H00002 | Acute lymphoblastic leukemia (ALL) (precursor T lymphoblastic leukemia) | Q03164
                            (related) | 
| H00455 | Spinal muscular atrophy (SMA) | Q16637
                            (related) | 
| H00063 | Spinocerebellar ataxia (SCA) | Q99700
                            (related) | 
| H00480 | Non-syndromic X-linked mental retardation | Q99714
                            (related) | 
| H00658 | Syndromic X-linked mental retardation | Q99714
                            (related) | 
| H00925 | 2-Methyl-3-hydroxybutyryl-CoA dehydrogenase (MHBD) deficiency | Q99714
                            (related) | 
| MESH or OMIM | name | KNApSAcK metabolite | 
|---|---|---|
| D020964 | Embryo Loss | C00001917 | 
| D005317 | Fetal Growth Retardation | C00001917 | 
| D009336 | Necrosis | C00001917 | 
| D009369 | Neoplasms | C00001917 | 
| D009374 | Neoplasms, Experimental | C00001917 | 
| D012878 | Skin Neoplasms | C00001917 | 
| D002375 | Catalepsy | C00001824 |