Platycapnos spicata

• Index
• Plant Species
• Metabolite list (17)
• Human Protein
  / Gene in interactions
• Related Diseases

Species

KNApSAcK Entry

Organism name	Platycapnos spicata
Genus	Platycapnos
Family	Fumariaceae
Kingdom	Plantae

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NCBI taxonomy

Entry

Linked NCBI taxonomy name	Platycapnos spicata
Linked NCBI taxonomy ID	200995
Linked level	species

Family

Family in NCBI taxonomy	Papaveraceae
ID	3465

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy	Viridiplantae
ID	33090

Plant class

Plant class	eudicotyledons
ID	71240

Metabolite list (17)

KNApSAcK ID	name	ChEMBL link	CTD link	# of proteins in ChEMBL interaction / related OMIM / related KEGG DISEASE	# of genes in CTD interaction / related diseases	KCF-S cluster	phytochemical cluster	figure
C00001861	Glaucine / S-(+)-Glaucine / O,O-Dimethylisoboldine	CHEMBL36536 CHEMBL228082		14 / 8 / 6		No. 20	No. 4
C00028217	Domesticine / (+)-Domesticine	CHEMBL1808240				No. 20	No. 4
C00025675	Lauroscholtzine / 2-O-Methylboldine / N-Methyllaurotetanine / (+)-N-Methyllaurotetanine	CHEMBL464099		1 / 1 / 0		No. 20	No. 4
C00027551	Isodomesticine / (+)-1-Methoxy-2-hydroxy-9,10-methylenedioxyaporphine					No. 20	No. 4
C00027566	Nandigerine / Hernangerine / (+)-Nandigerine / (+)-Hernangerine	CHEMBL1190170				No. 20	No. 4
C00027238	Thalicmidine / Thaliporphine / (+)-Thaliporphine / (S)-O-Methylisoboldine	CHEMBL1394328 CHEMBL1397308	C080702	20 / 26 / 56		No. 20	No. 4
C00026016	Predicentrine / (+)-Predicentrine	CHEMBL404136				No. 20	No. 4
C00027330	Glauvine / Corunnine					No. 74
C00025995	Oxonantenine	CHEMBL1270949				No. 74
C00027457	Oxoglaucine / O-Methylatheroline	CHEMBL470881	C111587	25 / 27 / 24		No. 74
C00028142	Dehydronantenine					No. 416
C00028139	Dehydroglaucine					No. 439
C00027430	N-Methylsecoglaucine	CHEMBL1620038				No. 639
C00029099	Thalicthuberine	CHEMBL518852				No. 639
C00029100	Thalicthuberine N-oxide					No. 639
C00028853	Pontevedrine					No. 800
C00001906	Fumarin / Biflorine / Protopine / Fumarine / Corydinine	CHEMBL453019	C009093	5 / 5 / 4	2 / 0	No. 820	No. 4

Human Protein / Gene in interactions

43 ChEMBL Protein in interactions

accession	description	class description	KNApSAcK metabolite in interactions	# of diseases (OMIM / KEGG)
B2RXH2	Lysine-specific demethylase 4E	Enzyme	C00001861 C00001906 C00027238 C00027457	0 / 0
P08684	Cytochrome P450 3A4	Cytochrome P450 3A4	C00001906 C00027238 C00027457	0 / 1
P10635	Cytochrome P450 2D6	Cytochrome P450 2D6	C00001906 C00027238 C00027457	1 / 0
P10636	Microtubule-associated protein tau	Unclassified protein	C00001861 C00027238 C00027457	4 / 3
P33261	Cytochrome P450 2C19	Cytochrome P450 2C19	C00001906 C00027238 C00027457	1 / 1
P27695	DNA-(apurinic or apyrimidinic site) lyase	Enzyme	C00027238 C00027457	0 / 0
P29466	Caspase-1	C14	C00027238 C00027457	0 / 0
Q9UBT6	DNA polymerase kappa	Enzyme	C00027238 C00027457	0 / 0
Q96QE3	ATPase family AAA domain-containing protein 5	Unclassified protein	C00001861 C00027457	0 / 0
P15428	15-hydroxyprostaglandin dehydrogenase [NAD(+)]	Enzyme	C00027238 C00027457	2 / 2
Q99714	3-hydroxyacyl-CoA dehydrogenase type-2	Enzyme	C00001861 C00027238	3 / 3
P28482	Mitogen-activated protein kinase 1	Erk	C00027238 C00027457	0 / 0
Q03164	Histone-lysine N-methyltransferase 2A	Enzyme	C00027238 C00027457	1 / 2
Q9NR56	Muscleblind-like protein 1	Unclassified protein	C00001861 C00027457	1 / 0
P00352	Retinal dehydrogenase 1	Enzyme	C00001861 C00027238	0 / 0
O75496	Geminin	Unclassified protein	C00001861 C00027457	0 / 0
Q14761	Protein tyrosine phosphatase receptor type C-associated protein	Enzyme	C00001861	0 / 0
Q9GZR1	Sentrin-specific protease 6	Enzyme	C00001861	0 / 0
P39748	Flap endonuclease 1	Enzyme	C00027457	0 / 0
P42858	Huntingtin	Unclassified protein	C00027457	1 / 1
P84022	Mothers against decapentaplegic homolog 3	Unclassified protein	C00027457	2 / 0
Q9BQF6	Sentrin-specific protease 7	Enzyme	C00001861	0 / 0
Q9Y253	DNA polymerase eta	Enzyme	C00027457	1 / 1
P54132	Bloom syndrome protein	Enzyme	C00027238	1 / 2
P83916	Chromobox protein homolog 1	Unclassified protein	C00027457	0 / 0
P06280	Alpha-galactosidase A	Enzyme	C00027238	1 / 1
P11712	Cytochrome P450 2C9	Cytochrome P450 2C9	C00027457	0 / 1
P42574	Caspase-3	C14	C00001861	0 / 0
P10828	Thyroid hormone receptor beta	NR1A2	C00027238	3 / 1
P16473	Thyrotropin receptor	Glycohormone receptor	C00001906	3 / 2
P16050	Arachidonate 15-lipoxygenase	Enzyme	C00027238	0 / 0
P55210	Caspase-7	C14	C00027238	0 / 0
Q96LD8	Sentrin-specific protease 8	Enzyme	C00001861	0 / 0
P02545	Prelamin-A/C	Unclassified protein	C00027457	11 / 10
Q9UNA4	DNA polymerase iota	Enzyme	C00001861	0 / 0
Q92793	CREB-binding protein	Enzyme	C00027457	1 / 1
P06746	DNA polymerase beta	Enzyme	C00027457	0 / 0
P08908	5-hydroxytryptamine receptor 1A	Serotonin receptor	C00025675	1 / 0
Q9UIF8	Bromodomain adjacent to zinc finger domain protein 2B	Unclassified protein	C00027457	0 / 0
P04637	Cellular tumor antigen p53	Transcription Factor	C00027238	7 / 37
Q9NUW8	Tyrosyl-DNA phosphodiesterase 1	Enzyme	C00027457	1 / 1
O00255	Menin	Unclassified protein	C00027238	2 / 5
P43351	DNA repair protein RAD52 homolog	Unclassified protein	C00001861	0 / 0

2 Gene in CTD interactions

gene	gene name	gene description	KNApSAcK metabolite in interactions
1543	CYP1A1, AHH, AHRR, CP11, CYP1, P1-450, P450-C, P450DX	cytochrome P450, family 1, subfamily A, polypeptide 1 (EC:1.14.14.1)	C00001906
1544	CYP1A2, CP12, P3-450, P450(PA)	cytochrome P450, family 1, subfamily A, polypeptide 2 (EC:1.14.14.1)	C00001906

Related Diseases

Diseases related to proteins in ChEMBL interactions