Thalictrum simplex

• Index
• Plant Species
• Metabolite list (14)
• Human Protein
  / Gene in interactions
• Related Diseases

Species

KNApSAcK Entry

Organism name	Thalictrum simplex
Genus	Thalictrum
Family	Ranunculaceae
Kingdom	Plantae

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NCBI taxonomy

Entry

Linked NCBI taxonomy name	Thalictrum simplex
Linked NCBI taxonomy ID	495765
Linked level	species

Family

Family in NCBI taxonomy	Ranunculaceae
ID	3440

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy	Viridiplantae
ID	33090

Plant class

Plant class	eudicotyledons
ID	71240

Metabolite list (14)

KNApSAcK ID	name	ChEMBL link	CTD link	# of proteins in ChEMBL interaction / related OMIM / related KEGG DISEASE	# of genes in CTD interaction / related diseases	KCF-S cluster	phytochemical cluster	figure
C00001866	Hernandezine	CHEMBL504936	C067193	5 / 4 / 8		No. 10	No. 4
C00001923	Thalsimine					No. 10	No. 4
C00027238	Thalicmidine / Thaliporphine / (+)-Thaliporphine / (S)-O-Methylisoboldine	CHEMBL1394328 CHEMBL1397308	C080702	20 / 26 / 56		No. 20	No. 4
C00027447	Ocotein / Ocoteine / Thalicmin / Thalicmine	CHEMBL443099				No. 20	No. 4
C00027587	Preocoteine					No. 20	No. 4
C00027492	Thalicsimidine					No. 20	No. 4
C00027899	Argemonine	CHEMBL486987 CHEMBL1964569				No. 37	No. 4
C00027730	2-O-Demethylthalimonine / (-)-2-Demethylthalimonine					No. 37	No. 4
C00029110	Thalimonine / (-)-Thalimonine		C482652			No. 37	No. 4
C00027588	Preocoteine N-oxide					No. 286	No. 4
C00029099	Thalicthuberine	CHEMBL518852				No. 639
C00027575	Northalicthuberine					No. 639
C00029100	Thalicthuberine N-oxide					No. 639
C00027595	Thalihazine					No. 639

Human Protein / Gene in interactions

24 ChEMBL Protein in interactions

accession	description	class description	KNApSAcK metabolite in interactions	# of diseases (OMIM / KEGG)
P27695	DNA-(apurinic or apyrimidinic site) lyase	Enzyme	C00001866 C00027238	0 / 0
P55210	Caspase-7	C14	C00027238	0 / 0
P29466	Caspase-1	C14	C00027238	0 / 0
P10828	Thyroid hormone receptor beta	NR1A2	C00027238	3 / 1
P54132	Bloom syndrome protein	Enzyme	C00027238	1 / 2
P11473	Vitamin D3 receptor	NR1I1	C00001866	2 / 3
P00352	Retinal dehydrogenase 1	Enzyme	C00027238	0 / 0
P06280	Alpha-galactosidase A	Enzyme	C00027238	1 / 1
P28482	Mitogen-activated protein kinase 1	Erk	C00027238	0 / 0
Q99714	3-hydroxyacyl-CoA dehydrogenase type-2	Enzyme	C00027238	3 / 3
P15428	15-hydroxyprostaglandin dehydrogenase [NAD(+)]	Enzyme	C00027238	2 / 2
P16050	Arachidonate 15-lipoxygenase	Enzyme	C00027238	0 / 0
P04637	Cellular tumor antigen p53	Transcription Factor	C00027238	7 / 37
P33261	Cytochrome P450 2C19	Cytochrome P450 2C19	C00027238	1 / 1
P08684	Cytochrome P450 3A4	Cytochrome P450 3A4	C00027238	0 / 1
P10635	Cytochrome P450 2D6	Cytochrome P450 2D6	C00027238	1 / 0
P10636	Microtubule-associated protein tau	Unclassified protein	C00027238	4 / 3
Q9UBT6	DNA polymerase kappa	Enzyme	C00027238	0 / 0
B2RXH2	Lysine-specific demethylase 4E	Enzyme	C00027238	0 / 0
Q9NUW8	Tyrosyl-DNA phosphodiesterase 1	Enzyme	C00001866	1 / 1
O00255	Menin	Unclassified protein	C00027238	2 / 5
Q03164	Histone-lysine N-methyltransferase 2A	Enzyme	C00027238	1 / 2
Q13951	Core-binding factor subunit beta	Unclassified protein	C00001866	0 / 1
Q01196	Runt-related transcription factor 1	Unclassified protein	C00001866	1 / 4

Related Diseases

Diseases related to proteins in ChEMBL interactions