Goniothalamus amuyon
Species
KNApSAcK Entry
| Organism name | Goniothalamus amuyon |
|---|---|
| Genus | Goniothalamus |
| Family | Annonaceae |
| Kingdom | Plantae |
NCBI taxonomy
Entry
| Linked NCBI taxonomy name | Goniothalamus |
|---|---|
| Linked NCBI taxonomy ID | 261082 |
| Linked level | genus |
Family
| Family in NCBI taxonomy | Annonaceae |
|---|---|
| ID | 22140 |
Kingdom (Superkingdom)
| Kingdom (Superkingdom) in NCBI taxonomy | Viridiplantae |
|---|---|
| ID | 33090 |
Plant class
| Plant class | Magnoliophyta |
|---|---|
| ID | 3398 |
Metabolite list (17)
| KNApSAcK ID | name | ChEMBL link | CTD link |
# of proteins in
ChEMBL interaction / related OMIM / related KEGG DISEASE |
# of genes in
CTD interaction / related diseases |
KCF-S
cluster |
phytochemical
cluster |
figure |
|---|---|---|---|---|---|---|---|---|
C00007190
|
(+)-Pinoresinol
|
CHEMBL267963
CHEMBL487611 CHEMBL460862 |
C103298
|
7 / 5 / 6 | No. 38 | No. 21 |
|
|
|
C00001878
|
Liriodenine
/ Oxoushinsunine / Spermatheridine |
CHEMBL37736
|
C026980
|
5 / 3 / 1 | No. 74 |
|
||
|
C00025935
|
Lysicamine
/ Oxonuciferine |
CHEMBL510090
|
C069090
|
No. 74 |
|
|||
|
C00025791
|
Cepharanone B
/ Aristolactam BII / Aristololactam B II |
CHEMBL226772
|
C064674
|
No. 125 |
|
|||
|
C00027284
|
Goniopetaline
/ Goniopedaline / Aristolactam FII |
No. 125 |
|
|||||
|
C00029182
|
Velutinam
|
CHEMBL519045
|
No. 125 |
|
||||
|
C00029961
|
Cinnamic acid
/ .beta-Phenylacrylic acid |
CHEMBL27246
|
C029010
|
5 / 2 / 2 | 16 / 2 | No. 904 | No. 6 |
|
|
C00030422
|
Goniothalesdiol A
|
No. 960 |
|
|||||
|
C00029479
|
Veratric acid
/ 3,4-dimethoxybenzoic acid |
CHEMBL118903
|
C009333
|
10 / 6 / 6 | No. 1073 |
|
||
|
C00044408
|
(6R,7R,8R)-8-Methoxygoniodiol
|
CHEMBL465756
|
No. 3038 |
|
||||
|
C00044488
|
8-Chlorogoniodiol
|
CHEMBL506162
|
No. 3038 |
|
||||
|
C00044787
|
Goniothalamin epoxide
/ (+)-Goniothalamin oxide |
CHEMBL468242
|
No. 3082 |
|
||||
|
C00030420
|
Goniodiol-8-monoacetate
|
CHEMBL500869
|
No. 3434 |
|
||||
|
C00030419
|
Goniodiol-7-monoacetate
|
No. 3434 |
|
|||||
|
C00030651
|
Leiocarpin C
|
No. 4165 |
|
|||||
|
C00030421
|
Goniothalesacetate
|
No. 5075 |
|
|||||
|
C00028312
|
Griffiazanone A
/ Griffithazanone A |
No. 6318 |
|
Human Protein / Gene in interactions
27 ChEMBL Protein in interactions
| accession | description | class description | KNApSAcK metabolite in interactions |
# of diseases
(OMIM / KEGG) |
|---|---|---|---|---|
| P18031 | Tyrosine-protein phosphatase non-receptor type 1 | Tyr | C00029961 | 0 / 0 |
| P09917 | Arachidonate 5-lipoxygenase | Oxidoreductase | C00007190 | 0 / 0 |
| P35354 | Prostaglandin G/H synthase 2 | Oxidoreductase | C00007190 | 0 / 3 |
| P43166 | Carbonic anhydrase 7 | Lyase | C00029479 | 0 / 0 |
| Q03181 | Peroxisome proliferator-activated receptor delta | NR1C2 | C00007190 | 0 / 0 |
| P47989 | Xanthine dehydrogenase/oxidase | Oxidoreductase | C00029961 | 1 / 1 |
| P00918 | Carbonic anhydrase 2 | Lyase | C00029479 | 1 / 2 |
| P30926 | Neuronal acetylcholine receptor subunit beta-4 | CHRN beta | C00001878 | 0 / 0 |
| P32297 | Neuronal acetylcholine receptor subunit alpha-3 | CHRN alpha | C00001878 | 1 / 0 |
| P17787 | Neuronal acetylcholine receptor subunit beta-2 | CHRN beta | C00001878 | 1 / 1 |
| P43681 | Neuronal acetylcholine receptor subunit alpha-4 | CHRN alpha | C00001878 | 1 / 1 |
| P23280 | Carbonic anhydrase 6 | Lyase | C00029479 | 0 / 0 |
| Q14761 | Protein tyrosine phosphatase receptor type C-associated protein | Enzyme | C00001878 | 0 / 0 |
| Q9ULX7 | Carbonic anhydrase 14 | Lyase | C00029479 | 0 / 0 |
| O43570 | Carbonic anhydrase 12 | Lyase | C00029479 | 1 / 2 |
| Q8TDS4 | Hydroxycarboxylic acid receptor 2 | Hydroxycarboxylic acid receptor | C00029961 | 0 / 0 |
| P84022 | Mothers against decapentaplegic homolog 3 | Unclassified protein | C00029479 | 2 / 0 |
| P15121 | Aldose reductase | Enzyme | C00029961 | 0 / 0 |
| P00915 | Carbonic anhydrase 1 | Lyase | C00029479 | 0 / 0 |
| P37231 | Peroxisome proliferator-activated receptor gamma | NR1C3 | C00007190 | 5 / 3 |
| Q16790 | Carbonic anhydrase 9 | Lyase | C00029479 | 0 / 1 |
| Q96QE3 | ATPase family AAA domain-containing protein 5 | Unclassified protein | C00007190 | 0 / 0 |
| P03372 | Estrogen receptor | NR3A1 | C00029961 | 1 / 1 |
| P51580 | Thiopurine S-methyltransferase | Enzyme | C00029479 | 1 / 1 |
| Q07869 | Peroxisome proliferator-activated receptor alpha | NR1C1 | C00007190 | 0 / 0 |
| P22748 | Carbonic anhydrase 4 | Lyase | C00029479 | 1 / 1 |
| Q9H0H5 | Rac GTPase-activating protein 1 | Unclassified protein | C00007190 | 0 / 0 |
16 Gene in CTD interactions
| gene | gene name | gene description | KNApSAcK metabolite in interactions |
|---|---|---|---|
| 1586 | CYP17A1, CPT7, CYP17, P450C17, S17AH | cytochrome P450, family 17, subfamily A, polypeptide 1 (EC:1.14.99.9 4.1.2.30) |
C00029961
|
| 1548 | CYP2A6, CPA6, CYP2A, CYP2A3, CYPIIA6, P450C2A, P450PB | cytochrome P450, family 2, subfamily A, polypeptide 6 (EC:1.14.14.1) |
C00029961
|
| 1557 | CYP2C19, CPCJ, CYP2C, P450C2C, P450IIC19 | cytochrome P450, family 2, subfamily C, polypeptide 19 (EC:1.14.13.48 1.14.13.49 1.14.13.80) |
C00029961
|
| 1558 | CYP2C8, CPC8, CYPIIC8, MP-12/MP-20 | cytochrome P450, family 2, subfamily C, polypeptide 8 (EC:1.14.14.1) |
C00029961
|
| 1559 | CYP2C9, CPC9, CYP2C, CYP2C10, CYPIIC9, P450IIC9 | cytochrome P450, family 2, subfamily C, polypeptide 9 (EC:1.14.13.48 1.14.13.49 1.14.13.80) |
C00029961
|
| 1565 | CYP2D6, CPD6, CYP2D, CYP2D7AP, CYP2D7BP, CYP2D7P2, CYP2D8P2, CYP2DL1, CYPIID6, P450-DB1, P450C2D, P450DB1 | cytochrome P450, family 2, subfamily D, polypeptide 6 (EC:1.14.14.1) |
C00029961
|
| 1571 | CYP2E1, CPE1, CYP2E, P450-J, P450C2E | cytochrome P450, family 2, subfamily E, polypeptide 1 (EC:1.14.13.n7) |
C00029961
|
| 1576 | CYP3A4, CP33, CP34, CYP3A, CYP3A3, CYPIIIA3, CYPIIIA4, HLP, NF-25, P450C3, P450PCN1 | cytochrome P450, family 3, subfamily A, polypeptide 4 (EC:1.14.13.67 1.14.13.97 1.14.13.32 1.14.13.157) |
C00029961
|
| 338442 | HCAR2, GPR109A, HCA2, HM74a, HM74b, NIACR1, PUMAG, Puma-g | hydroxycarboxylic acid receptor 2 |
C00029961
|
| 3284 | HSD3B2, HSD3B, HSDB, SDR11E2 | hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2 (EC:1.1.1.145 5.3.3.1) |
C00029961
|
| 4846 | NOS3, ECNOS, eNOS | nitric oxide synthase 3 (endothelial cell) (EC:1.14.13.39) |
C00029961
|
| 7299 | TYR, ATN, CMM8, OCA1, OCA1A, OCAIA, SHEP3 | tyrosinase (EC:1.14.18.1) |
C00029961
|
| 54575 | UGT1A10, UDPGT, UGT-1J, UGT1-10, UGT1.10, UGT1J | UDP glucuronosyltransferase 1 family, polypeptide A10 (EC:2.4.1.17) |
C00029961
|
| 54659 | UGT1A3, UDPGT, UDPGT_1-3, UGT-1C, UGT1-03, UGT1.3, UGT1C | UDP glucuronosyltransferase 1 family, polypeptide A3 (EC:2.4.1.17) |
C00029961
|
| 54577 | UGT1A7, UDPGT, UDPGT_1-7, UGT-1G, UGT1-07, UGT1.7, UGT1G | UDP glucuronosyltransferase 1 family, polypeptide A7 (EC:2.4.1.17) |
C00029961
|
| 54576 | UGT1A8, UDPGT, UDPGT_1-8, UGT-1H, UGT1-08, UGT1.8, UGT1A8S, UGT1H | UDP glucuronosyltransferase 1 family, polypeptide A8 (EC:2.4.1.17) |
C00029961
|
Related Diseases
Diseases related to proteins in ChEMBL interactions
OMIM (16)
| OMIM | preferred title | UniProt |
|---|---|---|
| %606641 | Body mass index; bmi |
P37231
|
| #609338 | Carotid intimal medial thickness 1 |
P37231
|
| #114500 | Colorectal cancer; crc |
P84022
|
| #600513 | Epilepsy, nocturnal frontal lobe, 1; enfl1 |
P43681
|
| #605375 | Epilepsy, nocturnal frontal lobe, 3; enfl3 |
P17787
|
| #615363 | Estrogen resistance; estrr |
P03372
|
| #137800 | Glioma susceptibility 1; glm1 |
P37231
|
| #143860 | Hyperchlorhidrosis, isolated |
O43570
|
| #604367 | Lipodystrophy, familial partial, type 3; fpld3 |
P37231
|
| #613795 | Loeys-dietz syndrome, type 3; lds3 |
P84022
|
| #601665 | Obesity |
P37231
|
| #259730 | Osteopetrosis, autosomal recessive 3; optb3 |
P00918
|
| #600852 | Retinitis pigmentosa 17; rp17 |
P22748
|
| #612052 | Smoking as a quantitative trait locus 3; sqtl3 |
P32297
|
| #610460 | Thiopurine s-methyltransferase deficiency |
P51580
|
| #278300 | Xanthinuria, type i |
P47989
|
KEGG DISEASE (15)
| KEGG | name | UniProt |
|---|---|---|
| H01302 | Hyperchlorhidrosis isolated (HCHLH) |
O43570
(related)
|
| H00021 | Renal cell carcinoma |
O43570
(marker)
Q16790 (marker) |
| H00241 | Combined proximal and distal renal tubular acidosis (RTA type 3) |
P00918
(related)
|
| H00436 | Osteopetrosis |
P00918
(related)
|
| H00026 | Endometrial Cancer |
P03372
(marker)
|
| H00807 | Autosomal dominant nocturnal frontal lobe epilepsy (ADNFLE) |
P17787
(related)
P43681 (related) |
| H00527 | Retinitis pigmentosa (RP) |
P22748
(related)
|
| H00017 | Esophageal cancer |
P35354
(related)
|
| H00025 | Penile cancer |
P35354
(related)
|
| H00046 | Cholangiocarcinoma |
P35354
(related)
|
| H00032 | Thyroid cancer |
P37231
(related)
|
| H00409 | Type II diabetes mellitus |
P37231
(related)
|
| H00420 | Familial partial lipodystrophy (FPL) |
P37231
(related)
|
| H00192 | Xanthinuria |
P47989
(related)
|
| H00964 | Thiopurine S-methyltransferase deficiency (TPMT deficiency) |
P51580
(related)
|