Species

KNApSAcK Entry

Organism name Fumaria indica
Genus Fumaria
Family Fumariaceae
Kingdom Plantae

NCBI taxonomy

Entry

Linked NCBI taxonomy name Fumaria
Linked NCBI taxonomy ID 200992
Linked level genus

Family

Family in NCBI taxonomy Papaveraceae
ID 3465

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Viridiplantae
ID 33090

Plant class

Plant class eudicotyledons
ID 71240

Metabolite list (17)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE
# of genes in
CTD interaction
/ related diseases
KCF-S
cluster
phytochemical
cluster
figure
C00028450 External link 512 Lastourvilline
No. 20 No. 4
C00027487 External link 512 dl-Stylopine
/ Tetrahydrocoptisine
CHEMBL1922602
No. 37 No. 4
C00026095 External link 512 Stylopine
/ (-)-Stylopine
/ l-Tetrahydrocoptisine
/ (-)-Tetrahydrocoptisine
CHEMBL1922602
No. 37 No. 4
C00025397 External link 512 Rotundine
/ (-)-Bisnorargemonine
CHEMBL518908
CHEMBL1494954
1 / 0 / 0 No. 37 No. 4
C00025342 External link 512 Pseudopalmatine
/ 5,6-Dihydro-8-demethylcoralyne
CHEMBL376300
No. 155 No. 4
C00028801 External link 512 Paprazine
/ N-p-Coumaroyl-tyramine
/ trans-N-(p-Coumaroyl)tyramine
CHEMBL64286
No. 499
C00028283 External link 512 Fumaritine
No. 512 No. 4
C00001900 External link 512 Parfumine
/ d-Parfumine
/ (+)-Parfumine
CHEMBL1968957
No. 512 No. 4
C00028647 External link 512 Narlumicine
No. 605 No. 4
C00028800 External link 512 Papraine
No. 605 No. 4
C00028648 External link 512 Narlumidine
No. 605 No. 4
C00001906 External link 512 Fumarin
/ Biflorine
/ Protopine
/ Fumarine
/ Corydinine
CHEMBL453019
C009093
5 / 5 / 4 2 / 0 No. 820 No. 4
C00027151 External link 512 N-Methylcorydaldine
/ N-Methyl-6,7-dimethoxytetrahydroisoquinol-1-one
CHEMBL504722
5 / 3 / 7 No. 2199
C00027458 External link 512 Oxyhydrastinine
/ N-Methylnoroxyhydrastinine
C048352
No. 3603
C00028729 External link 512 Noroxyhydrastinine
CHEMBL449731
3 / 1 / 0 No. 3603
C00028281 External link 512 Fumaramine
C071824
No. 7242
C00028282 External link 512 Fumariflorine
No. 7410

Human Protein / Gene in interactions

12 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
P83916 Chromobox protein homolog 1 Unclassified protein C00027151 C00028729 0 / 0
B2RXH2 Lysine-specific demethylase 4E Enzyme C00001906 C00028729 0 / 0
P33261 Cytochrome P450 2C19 Cytochrome P450 2C19 C00001906 1 / 1
O75496 Geminin Unclassified protein C00027151 0 / 0
P43220 Glucagon-like peptide 1 receptor Glucagon-like peptide receptor C00027151 0 / 0
P10635 Cytochrome P450 2D6 Cytochrome P450 2D6 C00001906 1 / 0
Q9NR56 Muscleblind-like protein 1 Unclassified protein C00028729 1 / 0
P08684 Cytochrome P450 3A4 Cytochrome P450 3A4 C00001906 0 / 1
P16473 Thyrotropin receptor Glycohormone receptor C00001906 3 / 2
O00255 Menin Unclassified protein C00027151 2 / 5
Q03164 Histone-lysine N-methyltransferase 2A Enzyme C00027151 1 / 2
O94925 Glutaminase kidney isoform, mitochondrial Enzyme C00025397 0 / 0

2 Gene in CTD interactions

gene gene name gene description KNApSAcK metabolite in interactions
1543 CYP1A1, AHH, AHRR, CP11, CYP1, P1-450, P450-C, P450DX cytochrome P450, family 1, subfamily A, polypeptide 1 (EC:1.14.14.1) C00001906
1544 CYP1A2, CP12, P3-450, P450(PA) cytochrome P450, family 1, subfamily A, polypeptide 2 (EC:1.14.14.1) C00001906

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (9)

OMIM preferred title UniProt
#609535 Drug metabolism, poor, cyp2c19-related P33261
#608902 Drug metabolism, poor, cyp2d6-related P10635
#605130 Hairy elbows, short stature, facial dysmorphism, and developmental delay Q03164
#145000 Hyperparathyroidism 1; hrpt1 O00255
#603373 Hyperthyroidism, familial gestational P16473
#609152 Hyperthyroidism, nonautoimmune P16473
#275200 Hypothyroidism, congenital, nongoitrous, 1; chng1 P16473
#131100 Multiple endocrine neoplasia, type i; men1 O00255
#160900 Myotonic dystrophy 1; dm1 Q9NR56

KEGG DISEASE (11)

KEGG name UniProt
H00033 Adrenal carcinoma O00255 (related)
H00034 Carcinoid O00255 (related)
H00045 Malignant islet cell carcinoma O00255 (related)
H00246 Primary hyperparathyroidism O00255 (related)
H01102 Pituitary adenomas O00255 (related)
H00036 Osteosarcoma P08684 (marker)
H00250 Congenital nongoitrous hypothyroidism (CHNG) P16473 (related)
H01269 Congenital hyperthyroidism P16473 (related)
H01171 Poor drug metabolism (PM) P33261 (related)
H00001 Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) Q03164 (related)
Q03164 (marker)
H00002 Acute lymphoblastic leukemia (ALL) (precursor T lymphoblastic leukemia) Q03164 (related)