PCIDB

Alangium chinense

Organism name	Alangium chinense
Genus	Alangium
Family	Cornaceae / Aucubaceae / Garryaceae / Helwingiaceae
Kingdom	Plantae

Family in NCBI taxonomy	Cornaceae
ID	42219

Kingdom (Superkingdom) in NCBI taxonomy	Viridiplantae
ID	33090

Plant class	asterids
ID	71274

KNApSAcK ID	name	ChEMBL link	CTD link	# of proteins in ChEMBL interaction / related OMIM / related KEGG DISEASE	# of genes in CTD interaction / related diseases	KCF-S cluster	phytochemical cluster
C00002672	Salicin / Saligenin beta-D-glucopyranoside	CHEMBL334657 CHEMBL462997 CHEMBL1595746	C005696	5 / 1 / 4		No. 45	No. 72
C00032760	(-)-Benzyl beta-primeveroside / Benzyl alcohol beta-D-xylopyranosyl (1->6)-beta-D-glucopyranoside	CHEMBL1371061	C069904	3 / 1 / 1		No. 128	No. 72
C00033024	Henryoside					No. 152
C00032655	4',6'-O-(S)-hexahydroxydiphenoylsalicin					No. 818	No. 81
C00002015	(-)-Anabasine	CHEMBL280963 CHEMBL1496898 CHEMBL1526229	D000691	15 / 18 / 15	0 / 4	No. 2084	No. 1

accession	description	class description	KNApSAcK metabolite in interactions	# of diseases (OMIM / KEGG)
P27695	DNA-(apurinic or apyrimidinic site) lyase	Enzyme	C00002015 C00002672	0 / 0
P63092	Guanine nucleotide-binding protein G(s) subunit alpha isoforms short	Other membrane protein	C00002015	7 / 3
P35354	Prostaglandin G/H synthase 2	Oxidoreductase	C00002672	0 / 3
P06746	DNA polymerase beta	Enzyme	C00002015	0 / 0
P10253	Lysosomal alpha-glucosidase	Hydrolase	C00032760	1 / 1
P11712	Cytochrome P450 2C9	Cytochrome P450 2C9	C00002015	0 / 1
P17787	Neuronal acetylcholine receptor subunit beta-2	CHRN beta	C00002015	1 / 1
P43681	Neuronal acetylcholine receptor subunit alpha-4	CHRN alpha	C00002015	1 / 1
P11216	Glycogen phosphorylase, brain form	Enzyme	C00002672	0 / 0
P39748	Flap endonuclease 1	Enzyme	C00002015	0 / 0
O75496	Geminin	Unclassified protein	C00032760	0 / 0
Q16637	Survival motor neuron protein	Unclassified protein	C00002015	4 / 1
P36544	Neuronal acetylcholine receptor subunit alpha-7	CHRN alpha	C00002015	0 / 0
P05177	Cytochrome P450 1A2	Cytochrome P450 1A2	C00002015	0 / 0
P33261	Cytochrome P450 2C19	Cytochrome P450 2C19	C00002015	1 / 1
P08684	Cytochrome P450 3A4	Cytochrome P450 3A4	C00002015	0 / 1
Q9UNA4	DNA polymerase iota	Enzyme	C00002672	0 / 0
P10635	Cytochrome P450 2D6	Cytochrome P450 2D6	C00002015	1 / 0
B2RXH2	Lysine-specific demethylase 4E	Enzyme	C00032760	0 / 0
Q9NUW8	Tyrosyl-DNA phosphodiesterase 1	Enzyme	C00002672	1 / 1
O00255	Menin	Unclassified protein	C00002015	2 / 5
Q03164	Histone-lysine N-methyltransferase 2A	Enzyme	C00002015	1 / 2

OMIM	preferred title	UniProt
#219080	Acth-independent macronodular adrenal hyperplasia; aimah	P63092
#609535	Drug metabolism, poor, cyp2c19-related	P33261
#608902	Drug metabolism, poor, cyp2d6-related	P10635
#600513	Epilepsy, nocturnal frontal lobe, 1; enfl1	P43681
#605375	Epilepsy, nocturnal frontal lobe, 3; enfl3	P17787
#232300	Glycogen storage disease ii	P10253
#605130	Hairy elbows, short stature, facial dysmorphism, and developmental delay	Q03164
#145000	Hyperparathyroidism 1; hrpt1	O00255
#174800	Mccune-albright syndrome; mas	P63092
#131100	Multiple endocrine neoplasia, type i; men1	O00255
#166350	Osseous heteroplasia, progressive; poh	P63092
#102200	Pituitary adenoma, growth hormone-secreting	P63092
#103580	Pseudohypoparathyroidism, type ia; php1a	P63092
#603233	Pseudohypoparathyroidism, type ib; php1b	P63092
#612462	Pseudohypoparathyroidism, type ic; php1c	P63092
#253300	Spinal muscular atrophy, type i; sma1	Q16637
#253550	Spinal muscular atrophy, type ii; sma2	Q16637
#253400	Spinal muscular atrophy, type iii; sma3	Q16637
#271150	Spinal muscular atrophy, type iv; sma4	Q16637
#607250	Spinocerebellar ataxia, autosomal recessive, with axonal neuropathy; scan1	Q9NUW8

KEGG	name	UniProt
H00033	Adrenal carcinoma	O00255 (related)
H00034	Carcinoid	O00255 (related)
H00045	Malignant islet cell carcinoma	O00255 (related)
H00246	Primary hyperparathyroidism	O00255 (related)
H01102	Pituitary adenomas	O00255 (related)
H00036	Osteosarcoma	P08684 (marker)
H00069	Glycogen storage diseases (GSD)	P10253 (related)
H01205	Coumarin resistance	P11712 (related)
H00807	Autosomal dominant nocturnal frontal lobe epilepsy (ADNFLE)	P17787 (related) P43681 (related)
H01171	Poor drug metabolism (PM)	P33261 (related)
H00017	Esophageal cancer	P35354 (related)
H00025	Penile cancer	P35354 (related)
H00046	Cholangiocarcinoma	P35354 (related)
H00244	Pseudohypoparathyroidism	P63092 (related)
H00441	Progressive osseous heteroplasia (POH)	P63092 (related)
H00501	Fibrous dysplasia, polyostotic	P63092 (related)
H00001	Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia)	Q03164 (related) Q03164 (marker)
H00002	Acute lymphoblastic leukemia (ALL) (precursor T lymphoblastic leukemia)	Q03164 (related)
H00455	Spinal muscular atrophy (SMA)	Q16637 (related)
H00063	Spinocerebellar ataxia (SCA)	Q9NUW8 (related)