Species

KNApSAcK Entry

Organism name Hyacinthus orientalis
Genus Hyacinthus
Family Hyacinthaceae
Kingdom Plantae

NCBI taxonomy

Entry

Linked NCBI taxonomy name Hyacinthus orientalis
Linked NCBI taxonomy ID 82025
Linked level species

Family

Family in NCBI taxonomy Hyacinthaceae
ID 44985

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Viridiplantae
ID 33090

Plant class

Plant class Liliopsida
ID 4447

Metabolite list (21)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE
# of genes in
CTD interaction
/ related diseases
KCF-S
cluster
phytochemical
cluster
figure
C00006764 External link 512 Pelargonidin 3-glucoside-5-(6'''-malonylglucoside)
No. 1 No. 15
C00004468 External link 512 Tricin 7-rutinoside-4'-glucoside
No. 5 No. 15
C00006773 External link 512 Pelargonidin 3-(6''-p-coumarylglucoside)-5-(4'''-malonylglucoside)
No. 7 No. 15
C00014852 External link 512 Pelargonidin 3-[6-((Z)-p-coumaroyl)glucoside]-5-glucoside
No. 7 No. 15
C00006767 External link 512 Bisdemalonylsalvianin
No. 7 No. 15
C00006769 External link 512 Pelargonidin 3-(6''-ferulylglucoside)-5-glucoside
No. 7 No. 15
C00006772 External link 512 Pelargonidin 3-(6''-p-coumarylglucoside)-5-(6'''-acetylglucoside)
No. 7 No. 15
C00006777 External link 512 Monardaein
No. 7 No. 15
C00006775 External link 512 Monodemalonylsalvianin
No. 7 No. 15
C00006887 External link 512 Monodemalonylsalviadelphin
/ Delphinidin 3-[6-(caffeoylglucoside)]-5-[6-(malonylglucoside)]
No. 7 No. 15
C00014816 External link 512 Delphinidin 3-(6-(Z)-p-coumaroylglucoside)-5-(6-malonylglucoside)
No. 7 No. 15
C00006899 External link 512 Petunidin 3-(6''-p-coumarylglucoside)-5-(6'''-malonylglucoside)
No. 7 No. 15
C00006824 External link 512 Malonylshisonin
No. 7 No. 15
C00006884 External link 512 Awobanin
/ Delphinidin-3-(6-O-p-coumarylglucoside)-5-glucoside
No. 7 No. 15
C00006776 External link 512 Palargonidin 3-(6''-ferulylglucoside)-5-(6'''-malonylglucoside)
No. 7 No. 15
C00006800 External link 512 Hyacinthin
/ Cyanidin 3-(6-O-p-coumarylglucoside)
No. 30 No. 15
C00036713 External link 512 alpha-Homomannojirimycin
/ (+)-alpha-Homomannojirimycin
CHEMBL87169
CHEMBL320116
CHEMBL327137
CHEMBL501355
CHEMBL1169500
CHEMBL2093079
CHEMBL2093897
CHEMBL2111688
CHEMBL2114210
CHEMBL2115215
C093741
6 / 9 / 8 No. 667
C00002037 External link 512 DMDP
/ (+)-2,5-Dideoxy-2,5-imino-D-mannitol
/ 2R,5R-Dihydroxymethyl-3R,4R-dihydroxy-pyrrolidine
CHEMBL10437
CHEMBL312653
CHEMBL121093
CHEMBL259905
CHEMBL405957
CHEMBL469844
CHEMBL2008021
C043121
8 / 10 / 8 No. 667
C00036798 External link 512 beta-Homomannojirimycin
CHEMBL87169
CHEMBL320116
CHEMBL327137
CHEMBL501355
CHEMBL1169500
CHEMBL2093079
CHEMBL2093897
CHEMBL2111688
CHEMBL2114210
CHEMBL2115215
6 / 9 / 8 No. 667
C00029420 External link 512 1-Deoxynojirimycin
/ (+)-1-Deoxynojirimycin
CHEMBL11510
CHEMBL65131
CHEMBL307429
CHEMBL84844
CHEMBL110458
CHEMBL369297
CHEMBL179085
CHEMBL176206
CHEMBL179130
CHEMBL179347
CHEMBL179409
CHEMBL176021
CHEMBL369046
CHEMBL176209
CHEMBL368121
CHEMBL175901
CHEMBL1337303
D017485
33 / 27 / 27 No. 786 No. 1
C00002035 External link 512 1-Deoxymannojirimycin
/ (-)-Deoxymannojirimycin
CHEMBL11510
CHEMBL65131
CHEMBL307429
CHEMBL84844
CHEMBL110458
CHEMBL369297
CHEMBL179085
CHEMBL176206
CHEMBL179130
CHEMBL179347
CHEMBL179409
CHEMBL176021
CHEMBL369046
CHEMBL176209
CHEMBL368121
CHEMBL175901
CHEMBL1337303
33 / 27 / 27 No. 786 No. 1

Human Protein / Gene in interactions

34 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
P04062 Glucosylceramidase Enzyme C00002035 C00002037 C00029420 C00036713 C00036798 6 / 4
O43451 Maltase-glucoamylase, intestinal Hydrolase C00002035 C00002037 C00029420 C00036713 C00036798 0 / 0
P06280 Alpha-galactosidase A Enzyme C00002035 C00002037 C00029420 C00036713 C00036798 1 / 1
P04066 Tissue alpha-L-fucosidase Enzyme C00002035 C00002037 C00029420 C00036713 C00036798 1 / 2
P10253 Lysosomal alpha-glucosidase Hydrolase C00002035 C00002037 C00029420 C00036713 C00036798 1 / 1
Q9H227 Cytosolic beta-glucosidase Enzyme C00002035 C00002037 C00029420 0 / 0
P35573 Glycogen debranching enzyme Enzyme C00002035 C00002037 C00029420 1 / 1
Q14697 Neutral alpha-glucosidase AB Enzyme C00002035 C00002037 C00029420 0 / 0
O00462 Beta-mannosidase Enzyme C00002035 C00029420 1 / 2
P10828 Thyroid hormone receptor beta NR1A2 C00002035 C00029420 3 / 1
P11712 Cytochrome P450 2C9 Cytochrome P450 2C9 C00002035 C00029420 0 / 1
Q8TET4 Neutral alpha-glucosidase C Enzyme C00036713 C00036798 0 / 0
P23458 Tyrosine-protein kinase JAK1 Jakb C00002035 C00029420 0 / 0
P00352 Retinal dehydrogenase 1 Enzyme C00002035 C00029420 0 / 0
P14410 Sucrase-isomaltase, intestinal Enzyme C00002035 C00029420 1 / 1
P10635 Cytochrome P450 2D6 Cytochrome P450 2D6 C00002035 C00029420 1 / 0
Q13133 Oxysterols receptor LXR-alpha NR1H3 C00002035 C00029420 0 / 0
P16278 Beta-galactosidase Enzyme C00002035 C00029420 4 / 6
Q9HCG7 Non-lysosomal glucosylceramidase Enzyme C00002035 C00029420 1 / 0
P05177 Cytochrome P450 1A2 Cytochrome P450 1A2 C00002035 C00029420 0 / 0
P55055 Oxysterols receptor LXR-beta NR1H3 C00002035 C00029420 0 / 0
P09848 Lactase-phlorizin hydrolase Enzyme C00002035 C00029420 1 / 1
Q16739 Ceramide glucosyltransferase Transferase C00002035 C00029420 0 / 0
P16050 Arachidonate 15-lipoxygenase Enzyme C00002035 C00029420 0 / 0
P33261 Cytochrome P450 2C19 Cytochrome P450 2C19 C00002035 C00029420 1 / 1
P08684 Cytochrome P450 3A4 Cytochrome P450 3A4 C00002035 C00029420 0 / 1
P27695 DNA-(apurinic or apyrimidinic site) lyase Enzyme C00002035 C00029420 0 / 0
P21728 D(1A) dopamine receptor Dopamine receptor C00002035 C00029420 0 / 0
O43280 Trehalase Enzyme C00002035 C00029420 0 / 0
O00754 Lysosomal alpha-mannosidase Enzyme C00002035 C00029420 1 / 2
Q6P4F1 Alpha-(1,3)-fucosyltransferase 10 Enzyme C00002035 C00029420 0 / 0
Q9Y2E5 Epididymis-specific alpha-mannosidase Enzyme C00002035 C00029420 0 / 0
O00255 Menin Unclassified protein C00002035 C00029420 2 / 5
Q03164 Histone-lysine N-methyltransferase 2A Enzyme C00002035 C00029420 1 / 2

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (27)

OMIM preferred title UniProt
#609535 Drug metabolism, poor, cyp2c19-related P33261
#608902 Drug metabolism, poor, cyp2d6-related P10635
#301500 Fabry disease P06280
#230000 Fucosidosis P04066
#608013 Gaucher disease, perinatal lethal P04062
#230800 Gaucher disease, type i P04062
#230900 Gaucher disease, type ii P04062
#231000 Gaucher disease, type iii P04062
#231005 Gaucher disease, type iiic P04062
#232300 Glycogen storage disease ii P10253
#232400 Glycogen storage disease iii P35573
#230500 Gm1-gangliosidosis, type i P16278
#230600 Gm1-gangliosidosis, type ii P16278
#230650 Gm1-gangliosidosis, type iii P16278
#605130 Hairy elbows, short stature, facial dysmorphism, and developmental delay Q03164
#145000 Hyperparathyroidism 1; hrpt1 O00255
#223000 Lactase deficiency, congenital P09848
#248500 Mannosidosis, alpha b, lysosomal; mansa O00754
#248510 Mannosidosis, beta a, lysosomal; mansb O00462
#253010 Mucopolysaccharidosis type ivb P16278
#131100 Multiple endocrine neoplasia, type i; men1 O00255
#168600 Parkinson disease, late-onset; pd P04062
#614409 Spastic paraplegia 46, autosomal recessive; spg46 Q9HCG7
#222900 Sucrase-isomaltase deficiency, congenital; csid P14410
#188570 Thyroid hormone resistance, generalized, autosomal dominant; grth P10828
#274300 Thyroid hormone resistance, generalized, autosomal recessive; grth P10828
#145650 Thyroid hormone resistance, selective pituitary; prth P10828

KEGG DISEASE (27)

KEGG name UniProt
H00033 Adrenal carcinoma O00255 (related)
H00034 Carcinoid O00255 (related)
H00045 Malignant islet cell carcinoma O00255 (related)
H00246 Primary hyperparathyroidism O00255 (related)
H01102 Pituitary adenomas O00255 (related)
H00140 beta-Mannosidosis O00462 (related)
H00422 Glycoproteinoses O00462 (related)
O00754 (related)
P04066 (related)
P16278 (related)
H00139 alpha-Mannosidosis O00754 (related)
H00066 Lewy body dementia (LBD) P04062 (related)
H00126 Gaucher disease P04062 (related)
H00426 Defects in the degradation of ganglioside P04062 (related)
P16278 (related)
H00810 Progressive myoclonic epilepsy (PME) P04062 (related)
H00141 Fucosidosis P04066 (related)
H00125 Fabry disease P06280 (related)
H00036 Osteosarcoma P08684 (marker)
H00116 Congenital lactase deficiency P09848 (related)
H00069 Glycogen storage diseases (GSD) P10253 (related)
P35573 (related)
H00249 Thyroid hormone resistance syndrome P10828 (related)
H01205 Coumarin resistance P11712 (related)
H00115 Congenital sucrase-isomaltase deficiency P14410 (related)
H00123 Mucopolysaccharidosis type IV (MPS4) P16278 (related)
H00276 Galactosialidosis P16278 (related)
H00281 GM1 gangliosidosis P16278 (related)
H00421 Mucopolysaccharidosis (MPS) P16278 (related)
H01171 Poor drug metabolism (PM) P33261 (related)
H00001 Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) Q03164 (related)
Q03164 (marker)
H00002 Acute lymphoblastic leukemia (ALL) (precursor T lymphoblastic leukemia) Q03164 (related)