| Organism name | Atalantia monophylla |
|---|---|
| Genus | Atalantia |
| Family | Rutaceae |
| Kingdom | Plantae |
| Linked NCBI taxonomy name | Atalantia monophylla |
|---|---|
| Linked NCBI taxonomy ID | 159025 |
| Linked level | species |
| Family in NCBI taxonomy | Rutaceae |
|---|---|
| ID | 23513 |
| Kingdom (Superkingdom) in NCBI taxonomy | Viridiplantae |
|---|---|
| ID | 33090 |
| Plant class | rosids |
|---|---|
| ID | 71275 |
| KNApSAcK ID | name | ChEMBL link | CTD link |
# of proteins in
ChEMBL interaction / related OMIM / related KEGG DISEASE |
# of genes in
CTD interaction / related diseases |
KCF-S
cluster |
phytochemical
cluster |
figure |
|---|---|---|---|---|---|---|---|---|
|
C00013432
|
Carpachromene
/ 5,4'-Dihidroxy-6'',6''-dimethylpyrano[2'',3'':7,6]flavone / 5-Hydroxy-8-(4-hydroxyphenyl)-2,2-dimethyl-2H,6H-benzo[1,2-b:5,4-b']dipyran-6-one |
No. 24 | No. 15 |
|
||||
|
C00024249
|
Citrusinine I
|
CHEMBL451705
|
C062044
|
1 / 0 / 0 | No. 257 | No. 7 |
|
|
|
C00029763
|
Auraptene
|
CHEMBL307341
|
C105832
|
28 / 25 / 26 | 3 / 0 | No. 335 |
|
|
|
C00033590
|
6-Methoxyaurapten
/ 7-O-Geranylscopoletin / 6-Methoxy-7-geranyloxycoumarin |
CHEMBL2346913
|
No. 335 |
|
||||
|
C00024238
|
Buxifoliadine A
|
No. 469 | No. 7 |
|
||||
|
C00024267
|
N-Methylatalaphylline
|
No. 469 | No. 7 |
|
||||
|
C00002139
|
Atalaphylline
|
No. 469 | No. 7 |
|
||||
|
C00024263
|
Junosine
|
No. 469 | No. 7 |
|
||||
|
C00003103
|
(+)-alpha-Bisabolol
|
CHEMBL519167
CHEMBL491186 CHEMBL477832 CHEMBL1096927 CHEMBL1171719 CHEMBL1561544 CHEMBL2104360 |
8 / 4 / 13 | No. 541 | No. 38 |
|
||
|
C00024242
|
Buxifoliadine E
|
No. 1258 |
|
|||||
|
C00034078
|
N-Methylbuxifoliadine E
|
No. 1258 |
|
|||||
|
C00033744
|
Cycloatalaphylline A
|
No. 1258 |
|
|||||
|
C00024274
|
Yukocitrine
|
No. 1724 | No. 7 |
|
||||
|
C00011895
|
Norbisabolide
/ (R*,R*)-(+)-Dihydro-5-methyl-5-(4-methyl-3-cyclohexen-1-yl)-2(3H)-furanone |
No. 6079 |
|
| accession | description | class description | KNApSAcK metabolite in interactions |
# of diseases
(OMIM / KEGG) |
|---|---|---|---|---|
| P28482 | Mitogen-activated protein kinase 1 | Erk | C00003103 C00029763 | 0 / 0 |
| P08684 | Cytochrome P450 3A4 | Cytochrome P450 3A4 | C00003103 C00029763 | 0 / 1 |
| P16050 | Arachidonate 15-lipoxygenase | Enzyme | C00003103 C00029763 | 0 / 0 |
| O94782 | Ubiquitin carboxyl-terminal hydrolase 1 | Enzyme | C00003103 C00029763 | 0 / 0 |
| Q9UIF8 | Bromodomain adjacent to zinc finger domain protein 2B | Unclassified protein | C00029763 | 0 / 0 |
| P17405 | Sphingomyelin phosphodiesterase | Enzyme | C00029763 | 2 / 2 |
| P84022 | Mothers against decapentaplegic homolog 3 | Unclassified protein | C00029763 | 2 / 0 |
| O75496 | Geminin | Unclassified protein | C00029763 | 0 / 0 |
| P40763 | Signal transducer and activator of transcription 3 | Transcription Factor | C00003103 | 1 / 2 |
| P43220 | Glucagon-like peptide 1 receptor | Glucagon-like peptide receptor | C00029763 | 0 / 0 |
| Q9Y253 | DNA polymerase eta | Enzyme | C00029763 | 1 / 1 |
| Q9Y468 | Lethal(3)malignant brain tumor-like protein 1 | Unclassified protein | C00029763 | 0 / 0 |
| P83916 | Chromobox protein homolog 1 | Unclassified protein | C00029763 | 0 / 0 |
| Q13315 | Serine-protein kinase ATM | Atypical serine/threonine protein kinase PIKK subfamily | C00029763 | 1 / 4 |
| P06280 | Alpha-galactosidase A | Enzyme | C00029763 | 1 / 1 |
| Q96RI1 | Bile acid receptor | NR1H4 | C00029763 | 0 / 0 |
| P00352 | Retinal dehydrogenase 1 | Enzyme | C00029763 | 0 / 0 |
| P56817 | Beta-secretase 1 | A1A | C00029763 | 0 / 0 |
| Q99714 | 3-hydroxyacyl-CoA dehydrogenase type-2 | Enzyme | C00029763 | 3 / 3 |
| P15428 | 15-hydroxyprostaglandin dehydrogenase [NAD(+)] | Enzyme | C00029763 | 2 / 2 |
| P04062 | Glucosylceramidase | Enzyme | C00029763 | 6 / 4 |
| O60911 | Cathepsin L2 | C1A | C00024249 | 0 / 0 |
| P35354 | Prostaglandin G/H synthase 2 | Oxidoreductase | C00003103 | 0 / 3 |
| O75164 | Lysine-specific demethylase 4A | Enzyme | C00029763 | 0 / 0 |
| P10636 | Microtubule-associated protein tau | Unclassified protein | C00029763 | 4 / 3 |
| B2RXH2 | Lysine-specific demethylase 4E | Enzyme | C00029763 | 0 / 0 |
| Q96KQ7 | Histone-lysine N-methyltransferase EHMT2 | Enzyme | C00029763 | 0 / 0 |
| Q9NUW8 | Tyrosyl-DNA phosphodiesterase 1 | Enzyme | C00029763 | 1 / 1 |
| O00255 | Menin | Unclassified protein | C00003103 | 2 / 5 |
| Q03164 | Histone-lysine N-methyltransferase 2A | Enzyme | C00003103 | 1 / 2 |
| Q13951 | Core-binding factor subunit beta | Unclassified protein | C00029763 | 0 / 1 |
| Q01196 | Runt-related transcription factor 1 | Unclassified protein | C00029763 | 1 / 4 |
| Q13148 | TAR DNA-binding protein 43 | Unclassified protein | C00029763 | 1 / 1 |
| gene | gene name | gene description | KNApSAcK metabolite in interactions |
|---|---|---|---|
| 1543 | CYP1A1, AHH, AHRR, CP11, CYP1, P1-450, P450-C, P450DX | cytochrome P450, family 1, subfamily A, polypeptide 1 (EC:1.14.14.1) |
C00029763
|
| 5743 | PTGS2, COX-2, COX2, GRIPGHS, PGG/HS, PGHS-2, PHS-2, hCox-2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) (EC:1.14.99.1) |
C00029763
|
| 7422 | VEGFA, MVCD1, VEGF, VPF | vascular endothelial growth factor A |
C00029763
|
| OMIM | preferred title | UniProt |
|---|---|---|
| #300438 | 17-beta-hydroxysteroid dehydrogenase x deficiency |
Q99714
|
| #612069 | Amyotrophic lateral sclerosis 10, with or without frontotemporal dementia; als10 |
Q13148
|
| #208900 | Ataxia-telangiectasia; at |
Q13315
|
| #114500 | Colorectal cancer; crc |
P84022
|
| #119900 | Digital clubbing, isolated congenital |
P15428
|
| #301500 | Fabry disease |
P06280
|
| #600274 | Frontotemporal dementia; ftd |
P10636
|
| #608013 | Gaucher disease, perinatal lethal |
P04062
|
| #230800 | Gaucher disease, type i |
P04062
|
| #230900 | Gaucher disease, type ii |
P04062
|
| #231000 | Gaucher disease, type iii |
P04062
|
| #231005 | Gaucher disease, type iiic |
P04062
|
| #605130 | Hairy elbows, short stature, facial dysmorphism, and developmental delay |
Q03164
|
| #147060 | Hyper-ige recurrent infection syndrome, autosomal dominant |
P40763
|
| #145000 | Hyperparathyroidism 1; hrpt1 |
O00255
|
| #259100 | Hypertrophic osteoarthropathy, primary, autosomal recessive, 1; phoar1 |
P15428
|
| #613795 | Loeys-dietz syndrome, type 3; lds3 |
P84022
|
| #300705 | Mental retardation, x-linked 17; mrx17 |
Q99714
|
| #300220 | Mental retardation, x-linked, syndromic 10; mrxs10 |
Q99714
|
| #131100 | Multiple endocrine neoplasia, type i; men1 |
O00255
|
| #257200 | Niemann-pick disease, type a |
P17405
|
| #607616 | Niemann-pick disease, type b |
P17405
|
| #168600 | Parkinson disease, late-onset; pd |
P04062
|
| #260540 | Parkinson-dementia syndrome |
P10636
|
| #172700 | Pick disease of brain |
P10636
|
| #601399 | Platelet disorder, familial, with associated myeloid malignancy |
Q01196
|
| #607250 | Spinocerebellar ataxia, autosomal recessive, with axonal neuropathy; scan1 |
Q9NUW8
|
| #601104 | Supranuclear palsy, progressive, 1; psnp1 |
P10636
|
| #278750 | Xeroderma pigmentosum, variant type; xpv |
Q9Y253
|
| KEGG | name | UniProt |
|---|---|---|
| H00033 | Adrenal carcinoma |
O00255
(related)
|
| H00034 | Carcinoid |
O00255
(related)
|
| H00045 | Malignant islet cell carcinoma |
O00255
(related)
|
| H00246 | Primary hyperparathyroidism |
O00255
(related)
|
| H01102 | Pituitary adenomas |
O00255
(related)
|
| H00066 | Lewy body dementia (LBD) |
P04062
(related)
|
| H00126 | Gaucher disease |
P04062
(related)
|
| H00426 | Defects in the degradation of ganglioside |
P04062
(related)
|
| H00810 | Progressive myoclonic epilepsy (PME) |
P04062
(related)
|
| H00125 | Fabry disease |
P06280
(related)
|
| H00036 | Osteosarcoma |
P08684
(marker)
|
| H00058 | Amyotrophic lateral sclerosis (ALS) |
P10636
(related)
Q13148 (related) |
| H00077 | Progressive supranuclear palsy (PSP) |
P10636
(related)
|
| H00078 | Frontotemporal lobar degeneration (FTLD) |
P10636
(related)
|
| H00457 | Primary hypertrophic osteoarthropathy (PHO) |
P15428
(related)
|
| H01246 | Isolated congenital nail clubbing (ICNC) |
P15428
(related)
|
| H00137 | Niemann-Pick disease (NPD) typeA and B |
P17405
(related)
|
| H00424 | Defects in the degradation of sphingomyelin |
P17405
(related)
|
| H00017 | Esophageal cancer |
P35354
(related)
|
| H00025 | Penile cancer |
P35354
(related)
|
| H00046 | Cholangiocarcinoma |
P35354
(related)
|
| H00016 | Oral cancer |
P40763
(related)
|
| H00107 | Other well-defined immunodeficiency syndromes |
P40763
(related)
|
| H00001 | Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) |
Q01196
(related)
Q01196 (marker) Q03164 (related) Q03164 (marker) |
| H00003 | Acute myeloid leukemia (AML) |
Q01196
(related)
Q01196 (marker) Q13951 (marker) |
| H00004 | Chronic myeloid leukemia (CML) |
Q01196
(related)
|
| H00978 | Thrombocytopenia (THC) |
Q01196
(related)
|
| H00002 | Acute lymphoblastic leukemia (ALL) (precursor T lymphoblastic leukemia) |
Q03164
(related)
|
| H00005 | Chronic lymphocytic leukemia (CLL) |
Q13315
(related)
|
| H00064 | Ataxia telangiectasia (AT) |
Q13315
(related)
|
| H00094 | DNA repair defects |
Q13315
(related)
|
| H00848 | Ataxia with ocular apraxia (AOA) |
Q13315
(related)
|
| H00480 | Non-syndromic X-linked mental retardation |
Q99714
(related)
|
| H00658 | Syndromic X-linked mental retardation |
Q99714
(related)
|
| H00925 | 2-Methyl-3-hydroxybutyryl-CoA dehydrogenase (MHBD) deficiency |
Q99714
(related)
|
| H00063 | Spinocerebellar ataxia (SCA) |
Q9NUW8
(related)
|
| H00403 | Disorders of nucleotide excision repair |
Q9Y253
(related)
|