Gochnatia argentina
Species
KNApSAcK Entry
| Organism name | Gochnatia argentina |
|---|---|
| Genus | Gochnatia |
| Family | Asteraceae |
| Kingdom | Plantae |
NCBI taxonomy
Entry
| Linked NCBI taxonomy name | Gochnatia |
|---|---|
| Linked NCBI taxonomy ID | 41583 |
| Linked level | genus |
Family
| Family in NCBI taxonomy | Asteraceae |
|---|---|
| ID | 4210 |
Kingdom (Superkingdom)
| Kingdom (Superkingdom) in NCBI taxonomy | Viridiplantae |
|---|---|
| ID | 33090 |
Plant class
| Plant class | asterids |
|---|---|
| ID | 71274 |
Metabolite list (3)
| KNApSAcK ID | name | ChEMBL link | CTD link |
# of proteins in
ChEMBL interaction / related OMIM / related KEGG DISEASE |
# of genes in
CTD interaction / related diseases |
KCF-S
cluster |
phytochemical
cluster |
figure |
|---|---|---|---|---|---|---|---|---|
C00019875
|
Fraxidin
|
CHEMBL2334351
|
6 / 2 / 4 | No. 364 | No. 25 |
|
||
|
C00019809
|
Capensin
|
CHEMBL1327256
|
18 / 11 / 10 | No. 466 | No. 25 |
|
||
|
C00002473
|
Fraxetin
|
CHEMBL54909
|
C105671
|
32 / 21 / 23 | 6 / 0 | No. 864 | No. 25 |
|
Human Protein / Gene in interactions
36 ChEMBL Protein in interactions
| accession | description | class description | KNApSAcK metabolite in interactions |
# of diseases
(OMIM / KEGG) |
|---|---|---|---|---|
| Q99714 | 3-hydroxyacyl-CoA dehydrogenase type-2 | Enzyme | C00002473 C00019809 | 3 / 3 |
| Q9NUW8 | Tyrosyl-DNA phosphodiesterase 1 | Enzyme | C00002473 C00019809 | 1 / 1 |
| Q99700 | Ataxin-2 | Unclassified protein | C00002473 C00019809 | 1 / 1 |
| B2RXH2 | Lysine-specific demethylase 4E | Enzyme | C00002473 C00019809 | 0 / 0 |
| P43166 | Carbonic anhydrase 7 | Lyase | C00002473 C00019875 | 0 / 0 |
| P29466 | Caspase-1 | C14 | C00002473 C00019809 | 0 / 0 |
| Q8N1Q1 | Carbonic anhydrase 13 | Lyase | C00002473 C00019875 | 0 / 0 |
| P00918 | Carbonic anhydrase 2 | Lyase | C00002473 C00019875 | 1 / 2 |
| P11712 | Cytochrome P450 2C9 | Cytochrome P450 2C9 | C00002473 C00019809 | 0 / 1 |
| P10636 | Microtubule-associated protein tau | Unclassified protein | C00002473 C00019809 | 4 / 3 |
| O75164 | Lysine-specific demethylase 4A | Enzyme | C00002473 C00019809 | 0 / 0 |
| O43570 | Carbonic anhydrase 12 | Lyase | C00002473 C00019875 | 1 / 2 |
| P39748 | Flap endonuclease 1 | Enzyme | C00002473 C00019809 | 0 / 0 |
| O75496 | Geminin | Unclassified protein | C00002473 C00019809 | 0 / 0 |
| P00915 | Carbonic anhydrase 1 | Lyase | C00002473 C00019875 | 0 / 0 |
| P43220 | Glucagon-like peptide 1 receptor | Glucagon-like peptide receptor | C00002473 C00019809 | 0 / 0 |
| Q9UNA4 | DNA polymerase iota | Enzyme | C00002473 C00019809 | 0 / 0 |
| Q16790 | Carbonic anhydrase 9 | Lyase | C00002473 C00019875 | 0 / 1 |
| P33261 | Cytochrome P450 2C19 | Cytochrome P450 2C19 | C00002473 C00019809 | 1 / 1 |
| P55210 | Caspase-7 | C14 | C00002473 C00019809 | 0 / 0 |
| P10635 | Cytochrome P450 2D6 | Cytochrome P450 2D6 | C00019809 | 1 / 0 |
| P16050 | Arachidonate 15-lipoxygenase | Enzyme | C00002473 | 0 / 0 |
| P15428 | 15-hydroxyprostaglandin dehydrogenase [NAD(+)] | Enzyme | C00002473 | 2 / 2 |
| Q96QE3 | ATPase family AAA domain-containing protein 5 | Unclassified protein | C00019809 | 0 / 0 |
| P08684 | Cytochrome P450 3A4 | Cytochrome P450 3A4 | C00019809 | 0 / 1 |
| P28482 | Mitogen-activated protein kinase 1 | Erk | C00002473 | 0 / 0 |
| P00352 | Retinal dehydrogenase 1 | Enzyme | C00002473 | 0 / 0 |
| P27695 | DNA-(apurinic or apyrimidinic site) lyase | Enzyme | C00002473 | 0 / 0 |
| P23219 | Prostaglandin G/H synthase 1 | Oxidoreductase | C00002473 | 0 / 0 |
| Q9UBT6 | DNA polymerase kappa | Enzyme | C00002473 | 0 / 0 |
| P09917 | Arachidonate 5-lipoxygenase | Oxidoreductase | C00002473 | 0 / 0 |
| Q96KQ7 | Histone-lysine N-methyltransferase EHMT2 | Enzyme | C00019809 | 0 / 0 |
| Q16637 | Survival motor neuron protein | Unclassified protein | C00002473 | 4 / 1 |
| O00255 | Menin | Unclassified protein | C00002473 | 2 / 5 |
| Q03164 | Histone-lysine N-methyltransferase 2A | Enzyme | C00002473 | 1 / 2 |
| O94925 | Glutaminase kidney isoform, mitochondrial | Enzyme | C00002473 | 0 / 0 |
6 Gene in CTD interactions
| gene | gene name | gene description | KNApSAcK metabolite in interactions |
|---|---|---|---|
| 581 | BAX, BCL2L4 | BCL2-associated X protein |
C00002473
|
| 836 | CASP3, CPP32, CPP32B, SCA-1 | caspase 3, apoptosis-related cysteine peptidase (EC:3.4.22.56) |
C00002473
|
| 842 | CASP9, APAF-3, APAF3, ICE-LAP6, MCH6, PPP1R56 | caspase 9, apoptosis-related cysteine peptidase (EC:3.4.22.62) |
C00002473
|
| 847 | CAT | catalase (EC:1.11.1.6) |
C00002473
|
| 54205 | CYCS, CYC, HCS, THC4 | cytochrome c, somatic |
C00002473
|
| 6648 | SOD2, IPOB, MNSOD, MVCD6 | superoxide dismutase 2, mitochondrial (EC:1.15.1.1) |
C00002473
|
Related Diseases
Diseases related to proteins in ChEMBL interactions
OMIM (22)
| OMIM | preferred title | UniProt |
|---|---|---|
| #300438 | 17-beta-hydroxysteroid dehydrogenase x deficiency |
Q99714
|
| #119900 | Digital clubbing, isolated congenital |
P15428
|
| #609535 | Drug metabolism, poor, cyp2c19-related |
P33261
|
| #608902 | Drug metabolism, poor, cyp2d6-related |
P10635
|
| #600274 | Frontotemporal dementia; ftd |
P10636
|
| #605130 | Hairy elbows, short stature, facial dysmorphism, and developmental delay |
Q03164
|
| #143860 | Hyperchlorhidrosis, isolated |
O43570
|
| #145000 | Hyperparathyroidism 1; hrpt1 |
O00255
|
| #259100 | Hypertrophic osteoarthropathy, primary, autosomal recessive, 1; phoar1 |
P15428
|
| #300705 | Mental retardation, x-linked 17; mrx17 |
Q99714
|
| #300220 | Mental retardation, x-linked, syndromic 10; mrxs10 |
Q99714
|
| #131100 | Multiple endocrine neoplasia, type i; men1 |
O00255
|
| #259730 | Osteopetrosis, autosomal recessive 3; optb3 |
P00918
|
| #260540 | Parkinson-dementia syndrome |
P10636
|
| #172700 | Pick disease of brain |
P10636
|
| #253300 | Spinal muscular atrophy, type i; sma1 |
Q16637
|
| #253550 | Spinal muscular atrophy, type ii; sma2 |
Q16637
|
| #253400 | Spinal muscular atrophy, type iii; sma3 |
Q16637
|
| #271150 | Spinal muscular atrophy, type iv; sma4 |
Q16637
|
| #183090 | Spinocerebellar ataxia 2; sca2 |
Q99700
|
| #607250 | Spinocerebellar ataxia, autosomal recessive, with axonal neuropathy; scan1 |
Q9NUW8
|
| #601104 | Supranuclear palsy, progressive, 1; psnp1 |
P10636
|
KEGG DISEASE (24)
| KEGG | name | UniProt |
|---|---|---|
| H00033 | Adrenal carcinoma |
O00255
(related)
|
| H00034 | Carcinoid |
O00255
(related)
|
| H00045 | Malignant islet cell carcinoma |
O00255
(related)
|
| H00246 | Primary hyperparathyroidism |
O00255
(related)
|
| H01102 | Pituitary adenomas |
O00255
(related)
|
| H01302 | Hyperchlorhidrosis isolated (HCHLH) |
O43570
(related)
|
| H00021 | Renal cell carcinoma |
O43570
(marker)
Q16790 (marker) |
| H00241 | Combined proximal and distal renal tubular acidosis (RTA type 3) |
P00918
(related)
|
| H00436 | Osteopetrosis |
P00918
(related)
|
| H00036 | Osteosarcoma |
P08684
(marker)
|
| H00058 | Amyotrophic lateral sclerosis (ALS) |
P10636
(related)
|
| H00077 | Progressive supranuclear palsy (PSP) |
P10636
(related)
|
| H00078 | Frontotemporal lobar degeneration (FTLD) |
P10636
(related)
|
| H01205 | Coumarin resistance |
P11712
(related)
|
| H00457 | Primary hypertrophic osteoarthropathy (PHO) |
P15428
(related)
|
| H01246 | Isolated congenital nail clubbing (ICNC) |
P15428
(related)
|
| H01171 | Poor drug metabolism (PM) |
P33261
(related)
|
| H00001 | Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) |
Q03164
(related)
Q03164 (marker) |
| H00002 | Acute lymphoblastic leukemia (ALL) (precursor T lymphoblastic leukemia) |
Q03164
(related)
|
| H00455 | Spinal muscular atrophy (SMA) |
Q16637
(related)
|
| H00063 | Spinocerebellar ataxia (SCA) |
Q99700
(related)
Q9NUW8 (related) |
| H00480 | Non-syndromic X-linked mental retardation |
Q99714
(related)
|
| H00658 | Syndromic X-linked mental retardation |
Q99714
(related)
|
| H00925 | 2-Methyl-3-hydroxybutyryl-CoA dehydrogenase (MHBD) deficiency |
Q99714
(related)
|