Melodinus morsei
Species
KNApSAcK Entry
| Organism name | Melodinus morsei |
|---|---|
| Genus | Melodinus |
| Family | Apocynaceae |
| Kingdom | Plantae |
NCBI taxonomy
Entry
| Linked NCBI taxonomy name | Melodinus |
|---|---|
| Linked NCBI taxonomy ID | 141584 |
| Linked level | genus |
Family
| Family in NCBI taxonomy | Apocynaceae |
|---|---|
| ID | 4056 |
Kingdom (Superkingdom)
| Kingdom (Superkingdom) in NCBI taxonomy | Viridiplantae |
|---|---|
| ID | 33090 |
Plant class
| Plant class | asterids |
|---|---|
| ID | 71274 |
Metabolite list (12)
| KNApSAcK ID | name | ChEMBL link | CTD link |
# of proteins in
ChEMBL interaction / related OMIM / related KEGG DISEASE |
# of genes in
CTD interaction / related diseases |
KCF-S
cluster |
phytochemical
cluster |
figure |
|---|---|---|---|---|---|---|---|---|
C00024480
|
11-Hydroxytabersonine
|
CHEMBL2011510
|
No. 61 | No. 4 |
|
|||
|
C00024463
|
Vincadifformine
/ (-)-Vincadifformine / 6,7-Dihydrotabersonine |
CHEMBL251690
CHEMBL1617045 |
C456406
|
No. 61 | No. 4 |
|
||
|
C00007204
|
Isolariciresinol
/ (+)-Isolariciresinol |
CHEMBL399512
CHEMBL1760593 |
C060284
|
2 / 1 / 1 | No. 406 |
|
||
|
C00024464
|
(+)-Aspidospermidine
|
No. 430 | No. 4 |
|
||||
|
C00024612
|
Vincoline
/ 20-Epimelobaline |
No. 527 |
|
|||||
|
C00024498
|
19S-Vindolinine
/ 19-Epivindolinine / 20-Epivindolinine / 20-epi-Vindolinine |
CHEMBL1165590
CHEMBL1330793 |
15 / 8 / 12 | No. 527 |
|
|||
|
C00024454
|
Kopsinine
/ (-)-Kopsinine |
CHEMBL93355
CHEMBL253984 |
C061491
|
No. 571 |
|
|||
|
C00002591
|
(-)-Cubebin
/ beta-Cubebin / (-)-beta-Cubebin / (8R,8'R,9S)-Cubebin |
CHEMBL182001
CHEMBL399831 |
C433065
|
2 / 1 / 1 | 0 / 2 | No. 629 | No. 21 |
|
|
C00024497
|
/ 19-Epivindolinine N-oxide / 20-Epivindolinine N-oxide / 20-Epivindolinine Nb-oxide |
No. 2586 |
|
|||||
|
C00024615
|
Vindolinine
/ 19R-vindolinine / (-)-Vindolinine |
C009668
|
No. 2586 |
|
||||
|
C00024614
|
Vindolinine N-oxide
/ Vindolinine Nb-oxide |
No. 2586 |
|
|||||
|
C00024594
|
Rhazidine
|
C003301
|
No. 6782 |
|
Human Protein / Gene in interactions
17 ChEMBL Protein in interactions
| accession | description | class description | KNApSAcK metabolite in interactions |
# of diseases
(OMIM / KEGG) |
|---|---|---|---|---|
| P10635 | Cytochrome P450 2D6 | Cytochrome P450 2D6 | C00002591 C00007204 | 1 / 0 |
| P08684 | Cytochrome P450 3A4 | Cytochrome P450 3A4 | C00002591 C00007204 | 0 / 1 |
| Q96QE3 | ATPase family AAA domain-containing protein 5 | Unclassified protein | C00024498 | 0 / 0 |
| O75496 | Geminin | Unclassified protein | C00024498 | 0 / 0 |
| P51151 | Ras-related protein Rab-9A | Unclassified protein | C00024498 | 0 / 0 |
| P43220 | Glucagon-like peptide 1 receptor | Glucagon-like peptide receptor | C00024498 | 0 / 0 |
| Q9HC16 | DNA dC->dU-editing enzyme APOBEC-3G | Enzyme | C00024498 | 0 / 0 |
| O15118 | Niemann-Pick C1 protein | Unclassified protein | C00024498 | 1 / 1 |
| P84022 | Mothers against decapentaplegic homolog 3 | Unclassified protein | C00024498 | 2 / 0 |
| Q99700 | Ataxin-2 | Unclassified protein | C00024498 | 1 / 1 |
| O75164 | Lysine-specific demethylase 4A | Enzyme | C00024498 | 0 / 0 |
| Q16236 | Nuclear factor erythroid 2-related factor 2 | Unclassified protein | C00024498 | 0 / 0 |
| Q96KQ7 | Histone-lysine N-methyltransferase EHMT2 | Enzyme | C00024498 | 0 / 0 |
| O75874 | Isocitrate dehydrogenase [NADP] cytoplasmic | Enzyme | C00024498 | 1 / 0 |
| O00255 | Menin | Unclassified protein | C00024498 | 2 / 5 |
| Q03164 | Histone-lysine N-methyltransferase 2A | Enzyme | C00024498 | 1 / 2 |
| P01215 | Glycoprotein hormones alpha chain | Unclassified protein | C00024498 | 0 / 3 |
Related Diseases
Diseases related to proteins in ChEMBL interactions
OMIM (9)
| OMIM | preferred title | UniProt |
|---|---|---|
| #114500 | Colorectal cancer; crc |
P84022
|
| #608902 | Drug metabolism, poor, cyp2d6-related |
P10635
|
| #137800 | Glioma susceptibility 1; glm1 |
O75874
|
| #605130 | Hairy elbows, short stature, facial dysmorphism, and developmental delay |
Q03164
|
| #145000 | Hyperparathyroidism 1; hrpt1 |
O00255
|
| #613795 | Loeys-dietz syndrome, type 3; lds3 |
P84022
|
| #131100 | Multiple endocrine neoplasia, type i; men1 |
O00255
|
| #257220 | Niemann-pick disease, type c1; npc1 |
O15118
|
| #183090 | Spinocerebellar ataxia 2; sca2 |
Q99700
|
KEGG DISEASE (13)
| KEGG | name | UniProt |
|---|---|---|
| H00033 | Adrenal carcinoma |
O00255
(related)
|
| H00034 | Carcinoid |
O00255
(related)
|
| H00045 | Malignant islet cell carcinoma |
O00255
(related)
|
| H00246 | Primary hyperparathyroidism |
O00255
(related)
|
| H01102 | Pituitary adenomas |
O00255
(related)
|
| H00136 | Niemann-Pick disease type C (NPC) |
O15118
(related)
|
| H00081 | Hashimoto's thyroiditis |
P01215
(marker)
|
| H00082 | Graves' disease |
P01215
(marker)
|
| H00250 | Congenital nongoitrous hypothyroidism (CHNG) |
P01215
(marker)
|
| H00036 | Osteosarcoma |
P08684
(marker)
|
| H00001 | Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) |
Q03164
(related)
Q03164 (marker) |
| H00002 | Acute lymphoblastic leukemia (ALL) (precursor T lymphoblastic leukemia) |
Q03164
(related)
|
| H00063 | Spinocerebellar ataxia (SCA) |
Q99700
(related)
|