| Organism name | Cryptotympana sp. |
|---|---|
| Genus | Cryptotympana |
| Family | Cicadidae |
| Kingdom | Animalia |
| Linked NCBI taxonomy name | Cryptotympana |
|---|---|
| Linked NCBI taxonomy ID | 407120 |
| Linked level | genus |
| Family in NCBI taxonomy | Cicadidae |
|---|---|
| ID | 7033 |
| Kingdom (Superkingdom) in NCBI taxonomy | Metazoa |
|---|---|
| ID | 33208 |
| Plant class | |
|---|---|
| ID |
| KNApSAcK ID | name | ChEMBL link | CTD link |
# of proteins in
ChEMBL interaction / related OMIM / related KEGG DISEASE |
# of genes in
CTD interaction / related diseases |
KCF-S
cluster |
phytochemical
cluster |
figure |
|---|---|---|---|---|---|---|---|---|
|
C00002668
|
Protocatechuic acid
/ 3,4-Dihydroxybenzoic acid |
CHEMBL37537
|
C009091
|
33 / 19 / 19 | 2 / 0 | No. 817 | No. 81 |
|
|
C00018099
|
Catechaldehyde
/ Protocatechualdehyde / 3,4-Dihydroxybenzaldehyde |
CHEMBL222021
|
C005581
|
7 / 0 / 0 | 5 / 2 | No. 2076 |
|
|
|
C00033243
|
N-Acetyldopamine
|
CHEMBL137743
|
C006374
|
15 / 23 / 23 | No. 3468 |
|
||
|
C00032630
|
2-Oxo-N-acetyldopamine
|
C078501
|
No. 5869 |
|
| accession | description | class description | KNApSAcK metabolite in interactions |
# of diseases
(OMIM / KEGG) |
|---|---|---|---|---|
| B2RXH2 | Lysine-specific demethylase 4E | Enzyme | C00002668 C00018099 C00033243 | 0 / 0 |
| O94925 | Glutaminase kidney isoform, mitochondrial | Enzyme | C00002668 C00018099 | 0 / 0 |
| Q96KQ7 | Histone-lysine N-methyltransferase EHMT2 | Enzyme | C00018099 C00033243 | 0 / 0 |
| P10636 | Microtubule-associated protein tau | Unclassified protein | C00002668 C00033243 | 4 / 3 |
| Q9UNA4 | DNA polymerase iota | Enzyme | C00002668 C00018099 | 0 / 0 |
| P00915 | Carbonic anhydrase 1 | Lyase | C00002668 | 0 / 0 |
| P43166 | Carbonic anhydrase 7 | Lyase | C00002668 | 0 / 0 |
| P22894 | Neutrophil collagenase | M10A | C00002668 | 0 / 0 |
| P14780 | Matrix metalloproteinase-9 | M10A | C00002668 | 2 / 2 |
| P02545 | Prelamin-A/C | Unclassified protein | C00033243 | 11 / 10 |
| P00918 | Carbonic anhydrase 2 | Lyase | C00002668 | 1 / 2 |
| P02768 | Serum albumin | Secreted protein | C00002668 | 0 / 0 |
| P11712 | Cytochrome P450 2C9 | Cytochrome P450 2C9 | C00033243 | 0 / 1 |
| Q9GZT9 | Egl nine homolog 1 | Enzyme | C00002668 | 1 / 1 |
| P54132 | Bloom syndrome protein | Enzyme | C00033243 | 1 / 2 |
| P23280 | Carbonic anhydrase 6 | Lyase | C00002668 | 0 / 0 |
| Q9ULX7 | Carbonic anhydrase 14 | Lyase | C00002668 | 0 / 0 |
| P00352 | Retinal dehydrogenase 1 | Enzyme | C00033243 | 0 / 0 |
| P16581 | E-selectin | Adhesion | C00002668 | 0 / 0 |
| O43570 | Carbonic anhydrase 12 | Lyase | C00002668 | 1 / 2 |
| Q16665 | Hypoxia-inducible factor 1-alpha | Transcription Factor | C00033243 | 0 / 0 |
| O75496 | Geminin | Unclassified protein | C00002668 | 0 / 0 |
| P51151 | Ras-related protein Rab-9A | Unclassified protein | C00018099 | 0 / 0 |
| P15121 | Aldose reductase | Enzyme | C00002668 | 0 / 0 |
| P10253 | Lysosomal alpha-glucosidase | Hydrolase | C00002668 | 1 / 1 |
| P07711 | Cathepsin L1 | C1A | C00002668 | 0 / 0 |
| P03956 | Interstitial collagenase | M10A | C00002668 | 0 / 1 |
| Q9Y468 | Lethal(3)malignant brain tumor-like protein 1 | Unclassified protein | C00002668 | 0 / 0 |
| P05177 | Cytochrome P450 1A2 | Cytochrome P450 1A2 | C00033243 | 0 / 0 |
| Q16790 | Carbonic anhydrase 9 | Lyase | C00002668 | 0 / 1 |
| P08253 | 72 kDa type IV collagenase | M10A | C00002668 | 1 / 3 |
| Q99714 | 3-hydroxyacyl-CoA dehydrogenase type-2 | Enzyme | C00033243 | 3 / 3 |
| P15428 | 15-hydroxyprostaglandin dehydrogenase [NAD(+)] | Enzyme | C00033243 | 2 / 2 |
| P03372 | Estrogen receptor | NR3A1 | C00002668 | 1 / 1 |
| P14151 | L-selectin | Adhesion | C00002668 | 0 / 0 |
| P16109 | P-selectin | Adhesion | C00002668 | 1 / 0 |
| P33261 | Cytochrome P450 2C19 | Cytochrome P450 2C19 | C00033243 | 1 / 1 |
| P08684 | Cytochrome P450 3A4 | Cytochrome P450 3A4 | C00033243 | 0 / 1 |
| P06746 | DNA polymerase beta | Enzyme | C00002668 | 0 / 0 |
| O75164 | Lysine-specific demethylase 4A | Enzyme | C00018099 | 0 / 0 |
| Q13093 | Platelet-activating factor acetylhydrolase | Enzyme | C00002668 | 3 / 0 |
| Q99549 | M-phase phosphoprotein 8 | Unclassified protein | C00033243 | 0 / 0 |
| P08254 | Stromelysin-1 | M10A | C00002668 | 1 / 0 |
| P22748 | Carbonic anhydrase 4 | Lyase | C00002668 | 1 / 1 |
| P09917 | Arachidonate 5-lipoxygenase | Oxidoreductase | C00002668 | 0 / 0 |
| Q9UIF8 | Bromodomain adjacent to zinc finger domain protein 2B | Unclassified protein | C00018099 | 0 / 0 |
| Q13951 | Core-binding factor subunit beta | Unclassified protein | C00002668 | 0 / 1 |
| Q01196 | Runt-related transcription factor 1 | Unclassified protein | C00002668 | 1 / 4 |
| P10635 | Cytochrome P450 2D6 | Cytochrome P450 2D6 | C00033243 | 1 / 0 |
| gene | gene name | gene description | KNApSAcK metabolite in interactions |
|---|---|---|---|
| 177 | AGER, RAGE | advanced glycosylation end product-specific receptor |
C00018099
|
| 6285 | S100B, NEF, S100, S100-B, S100beta | S100 calcium binding protein B |
C00018099
|
| 4087 | SMAD2, JV18, JV18-1, MADH2, MADR2, hMAD-2, hSMAD2 | SMAD family member 2 |
C00018099
|
| 4088 | SMAD3, HSPC193, HsT17436, JV15-2, LDS1C, LDS3, MADH3 | SMAD family member 3 |
C00018099
|
| 7040 | TGFB1, CED, DPD1, LAP, TGFB, TGFbeta | transforming growth factor, beta 1 |
C00018099
|
| 1312 | COMT | catechol-O-methyltransferase (EC:2.1.1.6) |
C00002668
|
| 2023 | ENO1, ENO1L1, MPB1, NNE, PPH | enolase 1, (alpha) (EC:4.2.1.11) |
C00002668
|
| OMIM | preferred title | UniProt |
|---|---|---|
| #300438 | 17-beta-hydroxysteroid dehydrogenase x deficiency |
Q99714
|
| #600807 | Asthma, susceptibility to |
Q13093
|
| #210900 | Bloom syndrome; blm |
P54132
|
| #115200 | Cardiomyopathy, dilated, 1a; cmd1a |
P02545
|
| #212112 | Cardiomyopathy, dilated, with hypergonadotropic hypogonadism |
P02545
|
| #605588 | Charcot-marie-tooth disease, axonal, type 2b1; cmt2b1 |
P02545
|
| #614466 | Coronary heart disease, susceptibility to, 6; chds6 |
P08254
|
| #119900 | Digital clubbing, isolated congenital |
P15428
|
| #609535 | Drug metabolism, poor, cyp2c19-related |
P33261
|
| #608902 | Drug metabolism, poor, cyp2d6-related |
P10635
|
| #181350 | Emery-dreifuss muscular dystrophy 2, autosomal dominant; edmd2 |
P02545
|
| #609820 | Erythrocytosis, familial, 3; ecyt3 |
Q9GZT9
|
| #615363 | Estrogen resistance; estrr |
P03372
|
| #600274 | Frontotemporal dementia; ftd |
P10636
|
| #232300 | Glycogen storage disease ii |
P10253
|
| #610140 | Heart-hand syndrome, slovenian type |
P02545
|
| #176670 | Hutchinson-gilford progeria syndrome; hgps |
P02545
|
| #143860 | Hyperchlorhidrosis, isolated |
O43570
|
| #259100 | Hypertrophic osteoarthropathy, primary, autosomal recessive, 1; phoar1 |
P15428
|
| #147050 | Ige responsiveness, atopic; iger |
Q13093
|
| #603932 | Intervertebral disc disease; idd |
P14780
|
| #151660 | Lipodystrophy, familial partial, type 2; fpld2 |
P02545
|
| #248370 | Mandibuloacral dysplasia with type a lipodystrophy; mada |
P02545
|
| #300705 | Mental retardation, x-linked 17; mrx17 |
Q99714
|
| #300220 | Mental retardation, x-linked, syndromic 10; mrxs10 |
Q99714
|
| #613073 | Metaphyseal anadysplasia 2; mandp2 |
P14780
|
| #259600 | Multicentric osteolysis, nodulosis, and arthropathy; mona |
P08253
|
| #613205 | Muscular dystrophy, congenital, lmna-related |
P02545
|
| #159001 | Muscular dystrophy, limb-girdle, type 1b; lgmd1b |
P02545
|
| #259730 | Osteopetrosis, autosomal recessive 3; optb3 |
P00918
|
| #260540 | Parkinson-dementia syndrome |
P10636
|
| #172700 | Pick disease of brain |
P10636
|
| #601399 | Platelet disorder, familial, with associated myeloid malignancy |
Q01196
|
| #614278 | Platelet-activating factor acetylhydrolase deficiency; pafad |
Q13093
|
| #275210 | Restrictive dermopathy, lethal |
P02545
|
| #600852 | Retinitis pigmentosa 17; rp17 |
P22748
|
| #601367 | Stroke, ischemic |
P16109
|
| #601104 | Supranuclear palsy, progressive, 1; psnp1 |
P10636
|
| KEGG | name | UniProt |
|---|---|---|
| H01302 | Hyperchlorhidrosis isolated (HCHLH) |
O43570
(related)
|
| H00021 | Renal cell carcinoma |
O43570
(marker)
Q16790 (marker) |
| H00241 | Combined proximal and distal renal tubular acidosis (RTA type 3) |
P00918
(related)
|
| H00436 | Osteopetrosis |
P00918
(related)
|
| H00264 | Charcot-Marie-Tooth disease (CMT) |
P02545
(related)
|
| H00294 | Dilated cardiomyopathy (DCM) |
P02545
(related)
|
| H00420 | Familial partial lipodystrophy (FPL) |
P02545
(related)
|
| H00563 | Emery-Dreifuss muscular dystrophy |
P02545
(related)
|
| H00590 | Congenital muscular dystrophies (CMD/MDC) |
P02545
(related)
|
| H00593 | Limb-girdle muscular dystrophy (LGMD) |
P02545
(related)
|
| H00601 | Hutchinson-Gilford progeria syndrome |
P02545
(related)
|
| H00663 | Restrictive dermopathy |
P02545
(related)
|
| H00665 | Mandibuloacral dysplasia |
P02545
(related)
|
| H01216 | Left ventricular noncompaction (LVNC) |
P02545
(related)
|
| H00026 | Endometrial Cancer |
P03372
(marker)
|
| H00028 | Choriocarcinoma |
P03956
(related)
P08253 (related) |
| H00025 | Penile cancer |
P08253
(related)
P14780 (related) |
| H00472 | Torg-Winchester syndrome |
P08253
(related)
|
| H00036 | Osteosarcoma |
P08684
(marker)
|
| H00069 | Glycogen storage diseases (GSD) |
P10253
(related)
|
| H00058 | Amyotrophic lateral sclerosis (ALS) |
P10636
(related)
|
| H00077 | Progressive supranuclear palsy (PSP) |
P10636
(related)
|
| H00078 | Frontotemporal lobar degeneration (FTLD) |
P10636
(related)
|
| H01205 | Coumarin resistance |
P11712
(related)
|
| H00479 | Metaphyseal dysplasias |
P14780
(related)
|
| H00457 | Primary hypertrophic osteoarthropathy (PHO) |
P15428
(related)
|
| H01246 | Isolated congenital nail clubbing (ICNC) |
P15428
(related)
|
| H00527 | Retinitis pigmentosa (RP) |
P22748
(related)
|
| H01171 | Poor drug metabolism (PM) |
P33261
(related)
|
| H00094 | DNA repair defects |
P54132
(related)
|
| H00296 | Defects in RecQ helicases |
P54132
(related)
|
| H00001 | Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) |
Q01196
(related)
Q01196 (marker) |
| H00003 | Acute myeloid leukemia (AML) |
Q01196
(related)
Q01196 (marker) Q13951 (marker) |
| H00004 | Chronic myeloid leukemia (CML) |
Q01196
(related)
|
| H00978 | Thrombocytopenia (THC) |
Q01196
(related)
|
| H00480 | Non-syndromic X-linked mental retardation |
Q99714
(related)
|
| H00658 | Syndromic X-linked mental retardation |
Q99714
(related)
|
| H00925 | 2-Methyl-3-hydroxybutyryl-CoA dehydrogenase (MHBD) deficiency |
Q99714
(related)
|
| H00236 | Congenital polycythemia |
Q9GZT9
(related)
|