Syzygium aromaticum
Species
KNApSAcK Entry
| Organism name | Syzygium aromaticum |
|---|---|
| Genus | Syzygium |
| Family | Myrtaceae |
| Kingdom | Plantae |
NCBI taxonomy
Entry
| Linked NCBI taxonomy name | Syzygium aromaticum |
|---|---|
| Linked NCBI taxonomy ID | 219868 |
| Linked level | species |
Family
| Family in NCBI taxonomy | Myrtaceae |
|---|---|
| ID | 3931 |
Kingdom (Superkingdom)
| Kingdom (Superkingdom) in NCBI taxonomy | Viridiplantae |
|---|---|
| ID | 33090 |
Plant class
| Plant class | rosids |
|---|---|
| ID | 71275 |
Natural Activity
List (41)
| Species | Activity |
|---|---|
| Syzygium aromaticum (L.) Merr. & L.M. Perry | Analgesic |
| Syzygium aromaticum (L.) Merr. & L.M. Perry | Anesthetic |
| Syzygium aromaticum (L.) Merr. & L.M. Perry | Anthelminthic |
| Syzygium aromaticum (L.) Merr. & L.M. Perry | Antiaggregant |
| Syzygium aromaticum (L.) Merr. & L.M. Perry | Antialzheimeran |
| Syzygium aromaticum (L.) Merr. & L.M. Perry | Antiarthritic |
| Syzygium aromaticum (L.) Merr. & L.M. Perry | Antibacterial |
| Syzygium aromaticum (L.) Merr. & L.M. Perry | Anticancer |
| Syzygium aromaticum (L.) Merr. & L.M. Perry | Anticonvulsant |
| Syzygium aromaticum (L.) Merr. & L.M. Perry | Antidote |
| Syzygium aromaticum (L.) Merr. & L.M. Perry | Antiemetic |
| Syzygium aromaticum (L.) Merr. & L.M. Perry | Antiherpetic |
| Syzygium aromaticum (L.) Merr. & L.M. Perry | Antihistaminic |
| Syzygium aromaticum (L.) Merr. & L.M. Perry | Antiinflammatory |
| Syzygium aromaticum (L.) Merr. & L.M. Perry | Antimutagenic |
| Syzygium aromaticum (L.) Merr. & L.M. Perry | Antinitrosating |
| Syzygium aromaticum (L.) Merr. & L.M. Perry | Antioxidant |
| Syzygium aromaticum (L.) Merr. & L.M. Perry | Antiperspirant |
| Syzygium aromaticum (L.) Merr. & L.M. Perry | Antiseptic |
| Syzygium aromaticum (L.) Merr. & L.M. Perry | Antispasmodic |
| Syzygium aromaticum (L.) Merr. & L.M. Perry | Antiviral |
| Syzygium aromaticum (L.) Merr. & L.M. Perry | Candidicide |
| Syzygium aromaticum (L.) Merr. & L.M. Perry | Carminative |
| Syzygium aromaticum (L.) Merr. & L.M. Perry | Counteirritant |
| Syzygium aromaticum (L.) Merr. & L.M. Perry | Deodorant |
| Syzygium aromaticum (L.) Merr. & L.M. Perry | Digestive |
| Syzygium aromaticum (L.) Merr. & L.M. Perry | Expectorant |
| Syzygium aromaticum (L.) Merr. & L.M. Perry | Fungicide |
| Syzygium aromaticum (L.) Merr. & L.M. Perry | Insectifuge |
| Syzygium aromaticum (L.) Merr. & L.M. Perry | Larvicide |
| Syzygium aromaticum (L.) Merr. & L.M. Perry | Parasympaticolytic |
| Syzygium aromaticum (L.) Merr. & L.M. Perry | Peristaltic |
| Syzygium aromaticum (L.) Merr. & L.M. Perry | Rubefacient |
| Syzygium aromaticum (L.) Merr. & L.M. Perry | Stimulant |
| Syzygium aromaticum (L.) Merr. & L.M. Perry | Stomachic |
| Syzygium aromaticum (L.) Merr. & L.M. Perry | Tonic |
| Syzygium aromaticum (L.) Merr. & L.M. Perry | Tranquilizer |
| Syzygium aromaticum (L.) Merr. & L.M. Perry | Trichomonicide |
| Syzygium aromaticum (L.) Merr. & L.M. Perry | Trypsin-Potentiator |
| Syzygium aromaticum (L.) Merr. & L.M. Perry | Vasodilator |
| Syzygium aromaticum (L.) Merr. & L.M. Perry | Vermifuge |
Metabolite list (7)
| KNApSAcK ID | name | ChEMBL link | CTD link |
# of proteins in
ChEMBL interaction / related OMIM / related KEGG DISEASE |
# of genes in
CTD interaction / related diseases |
KCF-S
cluster |
phytochemical
cluster |
figure |
|---|---|---|---|---|---|---|---|---|
C00003647
|
Campesterol
/ 24alpha-Methylcholesterol / (24R)24-Methylcholest-5-en-3beta-ol |
CHEMBL520535
CHEMBL485421 CHEMBL1836653 |
C021273
|
No. 53 | No. 11 |
|
||
|
C00002909
|
Casuarictin
|
CHEMBL305099
CHEMBL446979 |
C073064
|
No. 226 | No. 81 |
|
||
|
C00002920
|
Eugeniin
|
CHEMBL450745
CHEMBL510512 |
C110634
|
1 / 1 / 0 | No. 302 | No. 81 |
|
|
|
C00002938
|
Tellimagrandin I
|
CHEMBL450376
|
C087926
|
7 / 0 | No. 302 | No. 81 |
|
|
|
C00019308
|
Doursterol
/ Daucosterin / 3-O-beta-D-Glucopyranosyl sitosterol / beta-Sitosterol 3-O-beta-D-glucopyranoside |
CHEMBL197711
CHEMBL506678 CHEMBL2304043 |
C011015
|
5 / 4 / 2 | 0 / 3 | No. 520 |
|
|
|
C00029509
|
Stigmasterol-3-O-beta-D-glucopyranoside
/ beta-Stigmasteryl 3-O-beta-D-glucopyranoside |
CHEMBL447335
|
C054293
|
2 / 0 / 0 | No. 520 |
|
||
|
C00002683
|
Vanillin
|
CHEMBL13883
|
18 / 8 / 9 | No. 1003 |
|
Human Protein / Gene in interactions
26 ChEMBL Protein in interactions
| accession | description | class description | KNApSAcK metabolite in interactions |
# of diseases
(OMIM / KEGG) |
|---|---|---|---|---|
| P18031 | Tyrosine-protein phosphatase non-receptor type 1 | Tyr | C00019308 | 0 / 0 |
| Q9HAW8 | UDP-glucuronosyltransferase 1-10 | Enzyme | C00002683 | 0 / 0 |
| P78527 | DNA-dependent protein kinase catalytic subunit | Atypical serine/threonine protein kinase PIKK subfamily | C00002683 | 0 / 0 |
| P06746 | DNA polymerase beta | Enzyme | C00019308 | 0 / 0 |
| P08047 | Transcription factor Sp1 | Unclassified protein | C00019308 | 0 / 0 |
| P19793 | Retinoic acid receptor RXR-alpha | NR2B1 | C00002683 | 0 / 0 |
| P51649 | Succinate-semialdehyde dehydrogenase, mitochondrial | Oxidoreductase | C00002683 | 1 / 1 |
| P34969 | 5-hydroxytryptamine receptor 7 | Serotonin receptor | C00002683 | 0 / 0 |
| P51452 | Dual specificity protein phosphatase 3 | Ser_Thr_Tyr | C00029509 | 0 / 0 |
| Q9HAW7 | UDP-glucuronosyltransferase 1-7 | Enzyme | C00002683 | 0 / 0 |
| P00352 | Retinal dehydrogenase 1 | Enzyme | C00002683 | 0 / 0 |
| O60656 | UDP-glucuronosyltransferase 1-9 | Enzyme | C00002683 | 0 / 0 |
| P00742 | Coagulation factor X | S1A | C00002920 | 1 / 0 |
| P49841 | Glycogen synthase kinase-3 beta | Gsk | C00019308 | 0 / 0 |
| O00519 | Fatty-acid amide hydrolase 1 | Enzyme | C00002683 | 0 / 0 |
| P00734 | Prothrombin | S1A | C00019308 | 4 / 2 |
| P80404 | 4-aminobutyrate aminotransferase, mitochondrial | Transferase | C00002683 | 1 / 1 |
| Q96RI1 | Bile acid receptor | NR1H4 | C00002683 | 0 / 0 |
| P35236 | Tyrosine-protein phosphatase non-receptor type 7 | Tyr | C00029509 | 0 / 0 |
| P15428 | 15-hydroxyprostaglandin dehydrogenase [NAD(+)] | Enzyme | C00002683 | 2 / 2 |
| Q9Y4X1 | UDP-glucuronosyltransferase 2A1 | Enzyme | C00002683 | 0 / 0 |
| P19224 | UDP-glucuronosyltransferase 1-6 | Enzyme | C00002683 | 0 / 0 |
| Q16236 | Nuclear factor erythroid 2-related factor 2 | Unclassified protein | C00002683 | 0 / 0 |
| P10275 | Androgen receptor | NR3C4 | C00002683 | 3 / 4 |
| Q9NUW8 | Tyrosyl-DNA phosphodiesterase 1 | Enzyme | C00002683 | 1 / 1 |
| O94925 | Glutaminase kidney isoform, mitochondrial | Enzyme | C00002683 | 0 / 0 |
7 Gene in CTD interactions
| gene | gene name | gene description | KNApSAcK metabolite in interactions |
|---|---|---|---|
| 43 | ACHE, ACEE, ARACHE, N-ACHE, YT | acetylcholinesterase (EC:3.1.1.7) |
C00002938
|
| 2623 | GATA1, ERYF1, GATA-1, GF-1, GF1, NF-E1, NFE1, XLANP, XLTDA, XLTT | GATA binding protein 1 (globin transcription factor 1) |
C00002938
|
| 2624 | GATA2, DCML, MONOMAC, NFE1B | GATA binding protein 2 |
C00002938
|
| 2993 | GYPA, CD235a, GPA, GPErik, GPSAT, HGpMiV, HGpMiXI, HGpSta(C), MN, MNS, PAS-2 | glycophorin A (MNS blood group) |
C00002938
|
| 3145 | HMBS, PBG-D, PBGD, PORC, UPS | hydroxymethylbilane synthase (EC:2.5.1.61) |
C00002938
|
| 3690 | ITGB3, BDPLT16, BDPLT2, CD61, GP3A, GPIIIa, GT | integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) |
C00002938
|
| 4778 | NFE2, NF-E2, p45 | nuclear factor, erythroid 2 |
C00002938
|
Related Diseases
Diseases related to proteins in ChEMBL interactions
OMIM (13)
| OMIM | preferred title | UniProt |
|---|---|---|
| #300068 | Androgen insensitivity syndrome; ais |
P10275
|
| #312300 | Androgen insensitivity, partial; pais |
P10275
|
| #119900 | Digital clubbing, isolated congenital |
P15428
|
| #227600 | Factor x deficiency |
P00742
|
| #613163 | Gaba-transaminase deficiency |
P80404
|
| #259100 | Hypertrophic osteoarthropathy, primary, autosomal recessive, 1; phoar1 |
P15428
|
| #614390 | Pregnancy loss, recurrent, susceptibility to, 2; rprgl2 |
P00734
|
| #613679 | Prothrombin deficiency, congenital |
P00734
|
| #313200 | Spinal and bulbar muscular atrophy, x-linked 1; smax1 |
P10275
|
| #607250 | Spinocerebellar ataxia, autosomal recessive, with axonal neuropathy; scan1 |
Q9NUW8
|
| #601367 | Stroke, ischemic |
P00734
|
| #271980 | Succinic semialdehyde dehydrogenase deficiency; ssadhd |
P51649
|
| #188050 | Thrombophilia due to thrombin defect; thph1 |
P00734
|
KEGG DISEASE (11)
| KEGG | name | UniProt |
|---|---|---|
| H00223 | Inherited thrombophilia |
P00734
(related)
|
| H01254 | Congenital prothrombin deficiency |
P00734
(related)
|
| H00024 | Prostate cancer |
P10275
(related)
|
| H00062 | Spinal and bulbar muscular atrophy (SBMA) |
P10275
(related)
|
| H00608 | 46,XY disorders of sex development (Disorders in androgen synthesis or action) |
P10275
(related)
|
| H00609 | 46,XY disorders of sex development (Other) |
P10275
(related)
|
| H00457 | Primary hypertrophic osteoarthropathy (PHO) |
P15428
(related)
|
| H01246 | Isolated congenital nail clubbing (ICNC) |
P15428
(related)
|
| H00835 | Succinic semialdehyde dehydrogenase (SSADH) deficiency |
P51649
(related)
|
| H01257 | GABA-transaminase deficiency |
P80404
(related)
|
| H00063 | Spinocerebellar ataxia (SCA) |
Q9NUW8
(related)
|