Species

KNApSAcK Entry

Organism name Cornus spp.
Genus Cornus
Family Cornaceae / Aucubaceae / Garryaceae / Helwingiaceae
Kingdom Plantae

NCBI taxonomy

Entry

Linked NCBI taxonomy name Cornus
Linked NCBI taxonomy ID 4281
Linked level genus

Family

Family in NCBI taxonomy Cornaceae
ID 42219

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Viridiplantae
ID 33090

Plant class

Plant class asterids
ID 71274

Metabolite list (4)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE
# of genes in
CTD interaction
/ related diseases
KCF-S
cluster
phytochemical
cluster
figure
C00006658 External link 512 Cyanidin 3-sophoroside
No. 1 No. 15
C00003102 External link 512 Cornin
/ Verbenalin
CHEMBL1080178
CHEMBL1375107
C000511
5 / 9 / 10 No. 56 No. 36
C00000320 External link 512 Geniposide
CHEMBL462894
CHEMBL1417490
CHEMBL1718933
C007835
3 / 2 / 3 3 / 0 No. 100 No. 36
C00002920 External link 512 Eugeniin
CHEMBL450745
CHEMBL510512
C110634
1 / 1 / 0 No. 302 No. 81

Human Protein / Gene in interactions

8 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
Q96QE3 ATPase family AAA domain-containing protein 5 Unclassified protein C00000320 C00003102 0 / 0
P11473 Vitamin D3 receptor NR1I1 C00000320 2 / 3
O75496 Geminin Unclassified protein C00000320 0 / 0
P00742 Coagulation factor X S1A C00002920 1 / 0
P84022 Mothers against decapentaplegic homolog 3 Unclassified protein C00003102 2 / 0
P10636 Microtubule-associated protein tau Unclassified protein C00003102 4 / 3
O00255 Menin Unclassified protein C00003102 2 / 5
Q03164 Histone-lysine N-methyltransferase 2A Enzyme C00003102 1 / 2

3 Gene in CTD interactions

gene gene name gene description KNApSAcK metabolite in interactions
581 BAX, BCL2L4 BCL2-associated X protein C00000320
596 BCL2, Bcl-2, PPP1R50 B-cell CLL/lymphoma 2 C00000320
836 CASP3, CPP32, CPP32B, SCA-1 caspase 3, apoptosis-related cysteine peptidase (EC:3.4.22.56) C00000320

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (12)

OMIM preferred title UniProt
#114500 Colorectal cancer; crc P84022
#227600 Factor x deficiency P00742
#600274 Frontotemporal dementia; ftd P10636
#605130 Hairy elbows, short stature, facial dysmorphism, and developmental delay Q03164
#145000 Hyperparathyroidism 1; hrpt1 O00255
#613795 Loeys-dietz syndrome, type 3; lds3 P84022
#131100 Multiple endocrine neoplasia, type i; men1 O00255
#607948 Mycobacterium tuberculosis, susceptibility to P11473
#260540 Parkinson-dementia syndrome P10636
#172700 Pick disease of brain P10636
#601104 Supranuclear palsy, progressive, 1; psnp1 P10636
#277440 Vitamin d-dependent rickets, type 2a; vddr2a P11473

KEGG DISEASE (13)

KEGG name UniProt
H00033 Adrenal carcinoma O00255 (related)
H00034 Carcinoid O00255 (related)
H00045 Malignant islet cell carcinoma O00255 (related)
H00246 Primary hyperparathyroidism O00255 (related)
H01102 Pituitary adenomas O00255 (related)
H00058 Amyotrophic lateral sclerosis (ALS) P10636 (related)
H00077 Progressive supranuclear palsy (PSP) P10636 (related)
H00078 Frontotemporal lobar degeneration (FTLD) P10636 (related)
H00342 Tuberculosis P11473 (related)
H00784 Localized autosomal recessive hypotrichosis P11473 (related)
H01143 Vitamin D-dependent rickets P11473 (related)
H00001 Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) Q03164 (related)
Q03164 (marker)
H00002 Acute lymphoblastic leukemia (ALL) (precursor T lymphoblastic leukemia) Q03164 (related)