Organism name | Cratoxylum cochinchinense |
---|---|
Genus | Cratoxylum |
Family | Hypericaceae |
Kingdom | Plantae |
Linked NCBI taxonomy name | Cratoxylum cochinchinense |
---|---|
Linked NCBI taxonomy ID | 271749 |
Linked level | species |
Family in NCBI taxonomy | Hypericaceae |
---|---|
ID | 629714 |
Kingdom (Superkingdom) in NCBI taxonomy | Viridiplantae |
---|---|
ID | 33090 |
Plant class | rosids |
---|---|
ID | 71275 |
KNApSAcK ID | name | ChEMBL link | CTD link |
# of proteins in
ChEMBL interaction / related OMIM / related KEGG DISEASE |
# of genes in
CTD interaction / related diseases |
KCF-S
cluster |
phytochemical
cluster |
figure |
---|---|---|---|---|---|---|---|---|
C00002963
![]() |
Mangostin
/ alpha-Mangostin |
CHEMBL323197
|
C021053
|
25 / 27 / 58 | 0 / 3 | No. 14 | No. 15 |
![]() |
C00029359
![]() |
1,3,7-Trihydroxy-2,4-di(3-methylbut-2-enyl)xanthone
|
CHEMBL1782240
|
1 / 0 / 0 | No. 14 | No. 15 |
![]() |
||
C00029819
![]() |
beta-Mangostin
|
CHEMBL261706
|
3 / 0 / 0 | No. 14 | No. 15 |
![]() |
||
C00029995
![]() |
Cochinchinone A
|
CHEMBL1782241
|
1 / 0 / 0 | No. 14 | No. 15 |
![]() |
||
C00029569
![]() |
5-O-Methylcelebixanthone
|
No. 15 | No. 15 |
![]() |
||||
C00029920
![]() |
Celebixanthone
|
No. 15 | No. 15 |
![]() |
||||
C00029379
![]() |
11-Hydroxy-1-isomangostin
|
CHEMBL1080697
|
2 / 0 / 0 | No. 47 | No. 15 |
![]() |
||
C00035281
![]() |
Cratoxylone
|
No. 47 | No. 15 |
![]() |
||||
C00036594
![]() |
5'-Demethoxycadensin G
|
No. 338 |
![]() |
|||||
C00040749
![]() |
(13E,17E)-Polypoda-7,13,17,21-tetraen-3beta-ol
/ (+)-(13E,17E)-Polypoda-7,13,17,21-tetraen-3beta-ol |
No. 801 | No. 50 |
![]() |
||||
C00029996
![]() |
Cochinchinone C
|
No. 2057 |
![]() |
accession | description | class description | KNApSAcK metabolite in interactions |
# of diseases
(OMIM / KEGG) |
---|---|---|---|---|
Q04206 | Transcription factor p65 | Transcription Factor | C00002963 C00029359 C00029379 C00029819 C00029995 | 0 / 0 |
P19838 | Nuclear factor NF-kappa-B p105 subunit | Transcription Factor | C00002963 C00029379 C00029819 | 0 / 0 |
P49327 | Fatty acid synthase | Transferase | C00002963 C00029819 | 0 / 0 |
Q00987 | E3 ubiquitin-protein ligase Mdm2 | Other nuclear protein | C00002963 | 1 / 5 |
P11712 | Cytochrome P450 2C9 | Cytochrome P450 2C9 | C00002963 | 0 / 1 |
P00352 | Retinal dehydrogenase 1 | Enzyme | C00002963 | 0 / 0 |
P17405 | Sphingomyelin phosphodiesterase | Enzyme | C00002963 | 2 / 2 |
O75604 | Ubiquitin carboxyl-terminal hydrolase 2 | Enzyme | C00002963 | 0 / 0 |
P11511 | Cytochrome P450 19A1 | Cytochrome P450 19A1 | C00002963 | 2 / 2 |
O60906 | Sphingomyelin phosphodiesterase 2 | Enzyme | C00002963 | 0 / 0 |
P18054 | Arachidonate 12-lipoxygenase, 12S-type | Enzyme | C00002963 | 2 / 0 |
P28482 | Mitogen-activated protein kinase 1 | Erk | C00002963 | 0 / 0 |
P10635 | Cytochrome P450 2D6 | Cytochrome P450 2D6 | C00002963 | 1 / 0 |
Q99714 | 3-hydroxyacyl-CoA dehydrogenase type-2 | Enzyme | C00002963 | 3 / 3 |
P15428 | 15-hydroxyprostaglandin dehydrogenase [NAD(+)] | Enzyme | C00002963 | 2 / 2 |
O14763 | Tumor necrosis factor receptor superfamily member 10B | Unclassified protein | C00002963 | 1 / 0 |
P04637 | Cellular tumor antigen p53 | Transcription Factor | C00002963 | 7 / 37 |
P16050 | Arachidonate 15-lipoxygenase | Enzyme | C00002963 | 0 / 0 |
P33261 | Cytochrome P450 2C19 | Cytochrome P450 2C19 | C00002963 | 1 / 1 |
P08684 | Cytochrome P450 3A4 | Cytochrome P450 3A4 | C00002963 | 0 / 1 |
P10636 | Microtubule-associated protein tau | Unclassified protein | C00002963 | 4 / 3 |
Q9UBT6 | DNA polymerase kappa | Enzyme | C00002963 | 0 / 0 |
B2RXH2 | Lysine-specific demethylase 4E | Enzyme | C00002963 | 0 / 0 |
O00255 | Menin | Unclassified protein | C00002963 | 2 / 5 |
Q03164 | Histone-lysine N-methyltransferase 2A | Enzyme | C00002963 | 1 / 2 |
OMIM | preferred title | UniProt |
---|---|---|
#300438 | 17-beta-hydroxysteroid dehydrogenase x deficiency |
Q99714
|
#614401 | Accelerated tumor formation, susceptibility to; actfs |
Q00987
|
#202300 | Adrenocortical carcinoma, hereditary; adcc |
P04637
|
#613546 | Aromatase deficiency |
P11511
|
#139300 | Aromatase excess syndrome; aexs |
P11511
|
#614740 | Basal cell carcinoma, susceptibility to, 7; bcc7 |
P04637
|
#114500 | Colorectal cancer; crc |
P18054
|
#119900 | Digital clubbing, isolated congenital |
P15428
|
#609535 | Drug metabolism, poor, cyp2c19-related |
P33261
|
#608902 | Drug metabolism, poor, cyp2d6-related |
P10635
|
#133239 | Esophageal cancer |
P04637
P18054 |
#600274 | Frontotemporal dementia; ftd |
P10636
|
#605130 | Hairy elbows, short stature, facial dysmorphism, and developmental delay |
Q03164
|
#145000 | Hyperparathyroidism 1; hrpt1 |
O00255
|
#259100 | Hypertrophic osteoarthropathy, primary, autosomal recessive, 1; phoar1 |
P15428
|
#151623 | Li-fraumeni syndrome 1; lfs1 |
P04637
|
#211980 | Lung cancer |
P04637
|
#300705 | Mental retardation, x-linked 17; mrx17 |
Q99714
|
#300220 | Mental retardation, x-linked, syndromic 10; mrxs10 |
Q99714
|
#131100 | Multiple endocrine neoplasia, type i; men1 |
O00255
|
#257200 | Niemann-pick disease, type a |
P17405
|
#607616 | Niemann-pick disease, type b |
P17405
|
#260500 | Papilloma of choroid plexus; cpp |
P04637
|
#260540 | Parkinson-dementia syndrome |
P10636
|
#172700 | Pick disease of brain |
P10636
|
#275355 | Squamous cell carcinoma, head and neck; hnscc |
O14763
P04637 |
#601104 | Supranuclear palsy, progressive, 1; psnp1 |
P10636
|
KEGG | name | UniProt |
---|---|---|
H00033 | Adrenal carcinoma |
O00255
(related)
P04637 (related) |
H00034 | Carcinoid |
O00255
(related)
|
H00045 | Malignant islet cell carcinoma |
O00255
(related)
|
H00246 | Primary hyperparathyroidism |
O00255
(related)
|
H01102 | Pituitary adenomas |
O00255
(related)
|
H00004 | Chronic myeloid leukemia (CML) |
P04637
(related)
|
H00005 | Chronic lymphocytic leukemia (CLL) |
P04637
(related)
|
H00006 | Hairy-cell leukemia |
P04637
(related)
|
H00008 | Burkitt lymphoma |
P04637
(related)
|
H00009 | Adult T-cell leukemia |
P04637
(related)
|
H00010 | Multiple myeloma |
P04637
(related)
|
H00013 | Small cell lung cancer |
P04637
(related)
|
H00014 | Non-small cell lung cancer |
P04637
(related)
|
H00015 | Malignant pleural mesothelioma |
P04637
(related)
|
H00016 | Oral cancer |
P04637
(related)
P04637 (marker) |
H00017 | Esophageal cancer |
P04637
(related)
P04637 (marker) |
H00018 | Gastric cancer |
P04637
(related)
|
H00019 | Pancreatic cancer |
P04637
(related)
P04637 (marker) |
H00020 | Colorectal cancer |
P04637
(related)
P04637 (marker) |
H00022 | Bladder cancer |
P04637
(related)
|
H00025 | Penile cancer |
P04637
(related)
P04637 (marker) Q00987 (related) |
H00026 | Endometrial Cancer |
P04637
(related)
|
H00027 | Ovarian cancer |
P04637
(related)
|
H00028 | Choriocarcinoma |
P04637
(related)
Q00987 (related) |
H00029 | Vulvar cancer |
P04637
(related)
|
H00031 | Breast cancer |
P04637
(related)
|
H00032 | Thyroid cancer |
P04637
(related)
|
H00036 | Osteosarcoma |
P04637
(related)
P08684 (marker) Q00987 (related) |
H00038 | Malignant melanoma |
P04637
(related)
|
H00039 | Basal cell carcinoma |
P04637
(related)
|
H00040 | Squamous cell carcinoma |
P04637
(related)
|
H00041 | Kaposi's sarcoma |
P04637
(related)
|
H00042 | Glioma |
P04637
(related)
P04637 (marker) Q00987 (related) |
H00044 | Cancer of the anal canal |
P04637
(related)
|
H00046 | Cholangiocarcinoma |
P04637
(related)
|
H00047 | Gallbladder cancer |
P04637
(related)
|
H00048 | Hepatocellular carcinoma |
P04637
(related)
|
H00055 | Laryngeal cancer |
P04637
(related)
P04637 (marker) |
H00881 | Li-Fraumeni syndrome |
P04637
(related)
|
H01007 | Choroid plexus papilloma |
P04637
(related)
|
H00021 | Renal cell carcinoma |
P04637
(marker)
|
H00058 | Amyotrophic lateral sclerosis (ALS) |
P10636
(related)
|
H00077 | Progressive supranuclear palsy (PSP) |
P10636
(related)
|
H00078 | Frontotemporal lobar degeneration (FTLD) |
P10636
(related)
|
H00599 | 46,XX disorders of sex development (Disorders related to androgen excess) |
P11511
(related)
|
H00794 | Aromatase excess syndrome |
P11511
(related)
|
H01205 | Coumarin resistance |
P11712
(related)
|
H00457 | Primary hypertrophic osteoarthropathy (PHO) |
P15428
(related)
|
H01246 | Isolated congenital nail clubbing (ICNC) |
P15428
(related)
|
H00137 | Niemann-Pick disease (NPD) typeA and B |
P17405
(related)
|
H00424 | Defects in the degradation of sphingomyelin |
P17405
(related)
|
H01171 | Poor drug metabolism (PM) |
P33261
(related)
|
H00037 | Alveolar rhabdomyosarcoma |
Q00987
(related)
|
H00001 | Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) |
Q03164
(related)
Q03164 (marker) |
H00002 | Acute lymphoblastic leukemia (ALL) (precursor T lymphoblastic leukemia) |
Q03164
(related)
|
H00480 | Non-syndromic X-linked mental retardation |
Q99714
(related)
|
H00658 | Syndromic X-linked mental retardation |
Q99714
(related)
|
H00925 | 2-Methyl-3-hydroxybutyryl-CoA dehydrogenase (MHBD) deficiency |
Q99714
(related)
|