| | PATHWAY: hsa00380 | |
Entry |
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Name |
Tryptophan metabolism - Homo sapiens (human) |
Class |
Metabolism; Amino acid metabolism
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Pathway map |
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Module |
hsa_M00037 | Melatonin biosynthesis, animals, tryptophan => serotonin => melatonin [PATH:hsa00380] |
hsa_M00038 | Tryptophan metabolism, tryptophan => kynurenine => 2-aminomuconate [PATH:hsa00380] |
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Network |
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Element |
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Drug |
D00505 | Phenelzine sulfate (USP) |
D00826 | Tranylcypromine sulfate (USP) |
D01888 | Safrazine hydrochloride (JAN) |
D08393 | Pirlindole hydrochloride |
D09975 | Telotristat etiprate (USAN) |
D11049 | Epacadostat (JAN/USAN/INN) |
D11318 | Rodatristat ethyl (USAN) |
D11413 | Linrodostat mesylate (USAN) |
D12407 | Eladocagene exuparvovec (USAN/INN) |
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Other DBs |
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Organism |
Homo sapiens (human) [GN: hsa]
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Gene |
55526 | DHTKD1; dehydrogenase E1 and transketolase domain containing 1 [KO:K15791] [EC:1.2.4.-] |
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Compound |
C01111 | 7,8-Dihydroxykynurenate |
C01144 | (S)-3-Hydroxybutanoyl-CoA |
C01249 | 7,8-Dihydro-7,8-dihydroxykynurenate |
C01252 | 4-(2-Aminophenyl)-2,4-dioxobutanoate |
C01717 | 4-Hydroxy-2-quinolinecarboxylic acid |
C02161 | 2-Aminophenoxazin-3-one |
C02937 | Indole-3-acetaldehyde oxime |
C03230 | (Indol-3-yl)glycolaldehyde |
C03574 | 2-Formylaminobenzaldehyde |
C03824 | 2-Aminomuconate semialdehyde |
C04409 | 2-Amino-3-carboxymuconate semialdehyde |
C05634 | 5-Hydroxyindoleacetaldehyde |
C05641 | 5-(3'-Carboxy-3'-oxopropenyl)-4,6-dihydroxypicolinate |
C05642 | Formyl-N-acetyl-5-methoxykynurenamine |
C05645 | 4-(2-Amino-3-hydroxyphenyl)-2,4-dioxobutanoate |
C05646 | 5-Hydroxyindolepyruvate |
C05647 | Formyl-5-hydroxykynurenamine |
C05648 | 5-Hydroxy-N-formylkynurenine |
C05652 | 4-(2-Amino-5-hydroxyphenyl)-2,4-dioxobutanoate |
C05654 | 5-(2'-Formylethyl)-4,6-dihydroxypicolinate |
C05655 | 5-(2'-Carboxyethyl)-4,6-dihydroxypicolinate |
C05656 | 5-(3'-Carboxy-3'-oxopropyl)-4,6-dihydroxypicolinate |
C05832 | 5-Hydroxyindoleacetylglycine |
C05835 | 2-Formaminobenzoylacetate |
C16516 | Indolylmethylthiohydroximate |
C16517 | Indolylmethyl-desulfoglucosinolate |
C16518 | S-(Indolylmethylthiohydroximoyl)-L-cysteine |
C22006 | (R)-(Indol-3-yl)lactate |
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Reference |
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Authors |
Woodward AW, Bartel B |
Title |
Auxin: regulation, action, and interaction. |
Journal |
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Related pathway |
hsa00400 | Phenylalanine, tyrosine and tryptophan biosynthesis |
hsa00760 | Nicotinate and nicotinamide metabolism |
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KO pathway |
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