KEGG   PATHWAY: sma00670
Entry
sma00670                    Pathway                                
Name
One carbon pool by folate - Streptomyces avermitilis
Class
Metabolism; Metabolism of cofactors and vitamins
Pathway map
sma00670  One carbon pool by folate
sma00670

Module
sma_M00035  Methionine degradation [PATH:sma00670]
sma_M00338  Cysteine biosynthesis, homocysteine + serine => cysteine [PATH:sma00670]
sma_M00555  Betaine biosynthesis, choline => betaine [PATH:sma00670]
sma_M00621  Glycine cleavage system [PATH:sma00670]
Other DBs
GO: 0035999
Organism
Streptomyces avermitilis [GN:sma]
Gene
SAVERM_1622  gbsA1; putative glycine betaine aldehyde dehydrogenase [KO:K00130] [EC:1.2.1.8]
SAVERM_2111  mmuM; putative homocysteine S-methyltransferase (S-methylmethionine-dependent) [KO:K00547] [EC:2.1.1.10]
SAVERM_2154  lpdA2; putative dihydrolipoamide dehydrogenase [KO:K00382] [EC:1.8.1.4]
SAVERM_2517  thyX; putative thymidylate synthase [KO:K03465] [EC:2.1.1.148]
SAVERM_2592  [KO:K00130] [EC:1.2.1.8]
SAVERM_2610  [KO:K00130] [EC:1.2.1.8]
SAVERM_2773  gcvT; putative glycine cleavage system protein T (aminomethyltransferase) [KO:K00605] [EC:2.1.2.10]
SAVERM_2774  gcvH; putative glycine cleavage system protein H [KO:K02437]
SAVERM_2775  glyA1; putative serine hydroxymethyltransferase [KO:K00600] [EC:2.1.2.1]
SAVERM_2908  glyA2; putative serine hydroxymethyltransferase [KO:K00600] [EC:2.1.2.1]
SAVERM_3419  glyA3; putative serine hydroxymethyltransferase [KO:K00600] [EC:2.1.2.1]
SAVERM_3434  gbsA2; putative glycine betaine aldehyde dehydrogenase [KO:K00130] [EC:1.2.1.8]
SAVERM_3442  folD1; putative methylenetetrahydrofolate dehydrogenase and methenyltetrahydrofolate cyclohydrolase [KO:K01491] [EC:1.5.1.5 3.5.4.9]
SAVERM_3444  purH; putative bifunctional purine biosynthesis protein [KO:K00602] [EC:2.1.2.3 3.5.4.10]
SAVERM_3445  purN; putative phosphoribosylglycinamide formyltransferase [KO:K11175] [EC:2.1.2.2]
SAVERM_3510  cysM1; putative cystathionine beta-synthase [KO:K01697] [EC:4.2.1.22]
SAVERM_3674  [KO:K01934] [EC:6.3.3.2]
SAVERM_3846  purU; putative formyltetrahydrofolate deformylase [KO:K01433] [EC:3.5.1.10]
SAVERM_4273  cysA; putative cystathionine/methionine gamma-synthase/lyase [KO:K01758] [EC:4.4.1.1]
SAVERM_5053  sahH; putative S-adenosyl-L-homocysteine hydrolase [KO:K01251] [EC:3.13.2.1]
SAVERM_543  folD2; putative methylenetetrahydrofolate dehydrogenase and methenyltetrahydrofolate cyclohydrolase [KO:K01491] [EC:1.5.1.5 3.5.4.9]
SAVERM_5615  [KO:K01697] [EC:4.2.1.22]
SAVERM_6024  lpdA1; putative dihydrolipoamide dehydrogenase [KO:K00382] [EC:1.8.1.4]
SAVERM_6100  metF; putative 5,10-methylenetetrahydrofolate reductase [KO:K00297] [EC:1.5.1.54]
SAVERM_6667  metH; putative 5-methyltetrahydrofolate:homocysteine S-methyltransferase [KO:K00548] [EC:2.1.1.13]
SAVERM_6874  metK; putative S-adenosylmethionine synthetase [KO:K00789] [EC:2.5.1.6]
SAVERM_6946  [KO:K17755] [EC:1.1.3.17]
SAVERM_6948  gbsA3; putative glycine betaine aldehyde dehydrogenase [KO:K00130] [EC:1.2.1.8]
SAVERM_6951  [KO:K00309]
SAVERM_6987  gcvP; putative glycine dehydrogenase [KO:K00281] [EC:1.4.4.2]
SAVERM_789  [KO:K00130] [EC:1.2.1.8]
Compound
C00002  ATP
C00019  S-Adenosyl-L-methionine
C00021  S-Adenosyl-L-homocysteine
C00037  Glycine
C00065  L-Serine
C00073  L-Methionine
C00097  L-Cysteine
C00101  Tetrahydrofolate
C00114  Choline
C00143  5,10-Methylenetetrahydrofolate
C00155  L-Homocysteine
C00212  Adenosine
C00213  Sarcosine
C00234  10-Formyltetrahydrofolate
C00364  dTMP
C00365  dUMP
C00415  Dihydrofolate
C00440  5-Methyltetrahydrofolate
C00445  5,10-Methenyltetrahydrofolate
C00504  Folate
C00576  Betaine aldehyde
C00664  5-Formiminotetrahydrofolate
C00719  Betaine
C01026  N,N-Dimethylglycine
C02291  L-Cystathionine
C03479  Folinic acid
Related
pathway
sma00260  Glycine, serine and threonine metabolism
sma00270  Cysteine and methionine metabolism
sma00790  Folate biosynthesis
KO pathway
ko00670   

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