PCIDB

KNApSAcK Metabolite C00003841

Metabolite

KNApSAcK Entry

id C00003841
Name Tetramethylscutellarein / 5,6,7,4'-Tetramethoxyflavone / Scutellarein 5,6,7,4'-tetramethyl ether / 5,6,7-Trimethoxy-2-(4-methoxyphenyl)-4H-1-benzopyran-4-one
CAS RN 1168-42-9
Standard InChI InChI=1S/C19H18O6/c1-21-12-7-5-11(6-8-12)14-9-13(20)17-15(25-14)10-16(22-2)18(23-3)19(17)24-4/h5-10H,1-4H3
Standard InChI (Main Layer) InChI=1S/C19H18O6/c1-21-12-7-5-11(6-8-12)14-9-13(20)17-15(25-14)10-16(22-2)18(23-3)19(17)24-4/h5-10H,1-4H3

Cluster

Phytochemical cluster No. 15
KCF-S cluster No. 8

Link

ChEMBL

By standard InChI CHEMBL75349
By standard InChI Main Layer CHEMBL75349

KEGG

By LinkDB C14472

CTD

By CAS RN C072809

Human Protein / Gene in interaction

9 ChEMBL Protein in interactions

accession description class description compound assay ID (# of activities) # of diseases
(OMIM / KEGG)
P33765 Adenosine receptor A3 Adenosine receptor CHEMBL75349 CHEMBL638578 (1)
0 / 0
P00352 Retinal dehydrogenase 1 Enzyme CHEMBL75349 CHEMBL1614458 (1)
0 / 0
P43220 Glucagon-like peptide 1 receptor Glucagon-like peptide receptor CHEMBL75349 CHEMBL2114788 (1)
0 / 0
Q96QE3 ATPase family AAA domain-containing protein 5 Unclassified protein CHEMBL75349 CHEMBL1738588 (1)
0 / 0
Q9UNA4 DNA polymerase iota Enzyme CHEMBL75349 CHEMBL1794483 (1)
0 / 0
Q16236 Nuclear factor erythroid 2-related factor 2 Unclassified protein CHEMBL75349 CHEMBL1738184 (1)
0 / 0
O00255 Menin Unclassified protein CHEMBL75349 CHEMBL1614257 (1)
2 / 5
Q03164 Histone-lysine N-methyltransferase 2A Enzyme CHEMBL75349 CHEMBL1614257 (1)
1 / 3
Q13148 TAR DNA-binding protein 43 Unclassified protein CHEMBL75349 CHEMBL2354287 (1)
1 / 1

Related Disease

Diseases related to proteins in ChEMBL interactions

OMIM (4)

OMIM preferred title UniProt
#612069 Amyotrophic lateral sclerosis 10, with or without frontotemporal dementia; als10 Q13148
#605130 Hairy elbows, short stature, facial dysmorphism, and developmental delay Q03164
#145000 Hyperparathyroidism 1; hrpt1 O00255
#131100 Multiple endocrine neoplasia, type i; men1 O00255

KEGG DISEASE (8)

KEGG disease name UniProt
H00033 Adrenal carcinoma O00255 (related)
H00034 Carcinoid O00255 (related)
H00045 Malignant islet cell carcinoma O00255 (related)
H00246 Primary hyperparathyroidism O00255 (related)
H01102 Pituitary adenomas O00255 (related)
H00001 Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) Q03164 (related)
Q03164 (marker)
H00002 Acute lymphoblastic leukemia (ALL) (precursor T lymphoblastic leukemia) Q03164 (related)
H00058 Amyotrophic lateral sclerosis (ALS) Q13148 (related)