Citrus aurantium

• Index
• Plant Species
• Metabolite list (43)
• Human Protein
  / Gene in interactions
• Related Diseases

Species

KNApSAcK Entry

Organism name	Citrus aurantium
Genus	Citrus
Family	Rutaceae
Kingdom	Plantae

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NCBI taxonomy

Entry

Linked NCBI taxonomy name	Citrus aurantium
Linked NCBI taxonomy ID	43166
Linked level	species

Family

Family in NCBI taxonomy	Rutaceae
ID	23513

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy	Viridiplantae
ID	33090

Plant class

Plant class	rosids
ID	71275

Metabolite list (43)

KNApSAcK ID	name	ChEMBL link	CTD link	# of proteins in ChEMBL interaction / related OMIM / related KEGG DISEASE	# of genes in CTD interaction / related diseases	KCF-S cluster	phytochemical cluster	figure
C00004508	Neodiosmin / Diosmetin 7-neohesperidoside / 7-[[2-O-(6-Deoxy-alpha-L-mannopyranosyl)-beta-D-glucopyranosyl]oxy]-5-hydroxy-2-(3-hydroxy-4-methoxyphenyl)-4H-1-benzopyran-4-one					No. 1	No. 15
C00004157	Rhoifolin / (-)-Rhoifolin	CHEMBL395990 CHEMBL1888642	C089378	2 / 0 / 3		No. 1	No. 15
C00004657	Auranetin		C090194			No. 8	No. 15
C00003912	Isosinensetin / 6-Demethoxynobiletin / 5,7,8,3',4'-Pentamethoxyflavone / 2-(3,4-Dimethoxyphenyl)-5,7,8-trimethoxy-4H-1-benzopyran-4-one	CHEMBL451707				No. 8	No. 15
C00003841	Tetramethylscutellarein / 5,6,7,4'-Tetramethoxyflavone / Scutellarein 5,6,7,4'-tetramethyl ether / 5,6,7-Trimethoxy-2-(4-methoxyphenyl)-4H-1-benzopyran-4-one	CHEMBL75349	C072809	9 / 4 / 8		No. 8	No. 15
C00003936	Demethylnobiletin / 5-Hydroxy-6,7,8,3',4'-pentamethoxyflavone / 2-(3,4-Dimethoxyphenyl)-5-hydroxy-6,7,8-trimethoxy-4H-1-benzopyran-4-one	CHEMBL75978		21 / 22 / 16		No. 8	No. 15
C00001076	Nobiletin / 3',4',5,6,7,8-Hexamethoxyflavone	CHEMBL76447	C008661	22 / 23 / 20	5 / 2	No. 8	No. 15
C00004673	5-Hydroxyauranetin / 5-Hydroxy-3,6,7,8,4'-pentamethoxyflavone / 5-Hydroxy-3,6,7,8-tetramethoxy-2-(4-methoxyphenyl)-4H-1-Benzopyran-4-one	CHEMBL504047				No. 8	No. 15
C00000931	Zeaxanthin / all-trans-Zeaxanthin	CHEMBL1357855 CHEMBL2359248	C005881	4 / 2 / 3	1 / 0	No. 26	No. 59
C00003131	beta-Farnesene / (E)-beta-Farnesene / beta-trans-Farnesene		C062671			No. 404	No. 38
C00048367	Curcumene	CHEMBL469717	C086829			No. 456	No. 38
C00000816	beta-Pinene	CHEMBL501351	C010789			No. 476	No. 35
C00000805	alpha-Pinene	CHEMBL442565	C005451	3 / 3 / 2	0 / 1	No. 476	No. 35
C00003110	Caryophyllene / (E)-Caryophyllene / beta-Caryophyllene / (-)-(E)-Caryophyllene / (E)-beta-Caryophyllene	CHEMBL445740 CHEMBL448700		2 / 3 / 7		No. 478	No. 38
C00003166	Nerolidol	CHEMBL25424 CHEMBL508801 CHEMBL561014 CHEMBL1923157		3 / 3 / 1		No. 726	No. 38
C00000823	Limonene	CHEMBL15799 CHEMBL449062	C008281	7 / 21 / 48	6 / 6	No. 848	No. 35
C00048326	Benzene acetonitrile					No. 885
C00002663	2-Phenylethanol / Phenethyl alcohol / Phenylethyl alcohol / beta-Phenethyl alcohol	CHEMBL448500	D010626	2 / 1 / 1		No. 885
C00003047	Linalool / (R)-linalool / (R)-(-)-3,7-Dimethyl-1,6-octadien-3-ol	CHEMBL25306 CHEMBL235672	C018584	6 / 8 / 2	35 / 4	No. 958	No. 34
C00000184	alpha-Thujene					No. 1343	No. 35
C00031258	Sabinene / 4(10)-Thujene	CHEMBL452687	C035127			No. 1343	No. 35
C00048310	Allo-Ocimene		C015659			No. 1698	No. 34
C00048486	Neo-allo-ocimene					No. 1698	No. 34
C00003040	p-Cymene	CHEMBL442915	C007210			No. 2172	No. 35
C00010974	o-Cymol / 0-Isopropyltoluene / 1-Isopropyl-2-methylbenzene		C046257			No. 2172	No. 35
C00000853	Myrcene	CHEMBL455491	C008574	3 / 3 / 3		No. 2285	No. 34
C00048315	alpha-Myrcene					No. 2285	No. 34
C00029353	(Z)-Jasmone / cis-Jasmone		C086299			No. 3251
C00000357	Hexanal	CHEMBL280331	C010463		7 / 0	No. 3593
C00001418	Indole	CHEMBL15844	C030374	13 / 5 / 6	6 / 0	No. 3673
C00000861	Terpinolene	CHEMBL454697	C027009		1 / 0	No. 3725
C00034600	Methyl anthranilate	CHEMBL1493986	C038892	3 / 3 / 3		No. 4170
C00048248	(Z)-Ocimene / cis-Ocimene					No. 4949
C00048263	2,6-Dimethyl-1,3,5,7-octatetraene					No. 4953
C00002780	Subaphyllin		C065165			No. 5072
C00034775	6-Methyl-5-hepten-2-one	CHEMBL46340	C029750			No. 5297
C00048304	Acetone	CHEMBL14253	D000096	1 / 11 / 10	10 / 8	No. 5308
C00034989	(E)-Ocimene / trans-Ocimene					No. 6181
C00034452	Benzaldehyde	CHEMBL15972	C032175	8 / 7 / 3	3 / 1	No. 6311
C00048438	Isopropanol	CHEMBL582	D019840	5 / 17 / 15	33 / 2	No. 6812
C00048350	Carvyl acetate	CHEMBL1351619		4 / 3 / 2		No. 6846
C00048498	n-Phenylformamide	CHEMBL1232659	C045976	6 / 2 / 0		No. 8296
C00019560	Ethanol	CHEMBL545	D000431	92 / 39 / 33	199 / 193	No. 8862

Human Protein / Gene in interactions

160 ChEMBL Protein in interactions

accession	description	class description	KNApSAcK metabolite in interactions	# of diseases (OMIM / KEGG)
P00352	Retinal dehydrogenase 1	Enzyme	C00001076 C00003841 C00003936 C00019560 C00034452 C00034600 C00048438 C00048498	0 / 0
Q16236	Nuclear factor erythroid 2-related factor 2	Unclassified protein	C00000823 C00003841 C00034600 C00048350 C00048438 C00048498	0 / 0
P16473	Thyrotropin receptor	Glycohormone receptor	C00000805 C00000853 C00019560 C00048350	3 / 2
P10828	Thyroid hormone receptor beta	NR1A2	C00000823 C00003047 C00003166 C00048438	3 / 1
P02545	Prelamin-A/C	Unclassified protein	C00000823 C00003936 C00048304 C00048438	11 / 10
O75496	Geminin	Unclassified protein	C00000931 C00001076 C00002663 C00048498	0 / 0
P28482	Mitogen-activated protein kinase 1	Erk	C00000805 C00001076 C00003936 C00019560	0 / 0
Q03181	Peroxisome proliferator-activated receptor delta	NR1C2	C00000823 C00034452 C00048498	0 / 0
P35354	Prostaglandin G/H synthase 2	Oxidoreductase	C00000823 C00004157 C00019560	0 / 3
P16050	Arachidonate 15-lipoxygenase	Enzyme	C00003047 C00003166 C00048350	0 / 0
Q03164	Histone-lysine N-methyltransferase 2A	Enzyme	C00001076 C00003110 C00003841	1 / 2
O00255	Menin	Unclassified protein	C00001076 C00003110 C00003841	2 / 5
P51449	Nuclear receptor ROR-gamma	Nuclear hormone receptor subfamily 1 group F member 3	C00000805 C00019560 C00048350	0 / 0
O94782	Ubiquitin carboxyl-terminal hydrolase 1	Enzyme	C00000931 C00003166 C00004157	0 / 0
P08684	Cytochrome P450 3A4	Cytochrome P450 3A4	C00001076 C00003936 C00019560	0 / 1
Q96KQ7	Histone-lysine N-methyltransferase EHMT2	Enzyme	C00000931 C00001076	0 / 0
P04150	Glucocorticoid receptor	NR3C1	C00000853 C00019560	0 / 1
Q99714	3-hydroxyacyl-CoA dehydrogenase type-2	Enzyme	C00001076 C00034600	3 / 3
P10636	Microtubule-associated protein tau	Unclassified protein	C00001076 C00003936	4 / 3
Q96QE3	ATPase family AAA domain-containing protein 5	Unclassified protein	C00001076 C00003841	0 / 0
P83916	Chromobox protein homolog 1	Unclassified protein	C00003047 C00048498	0 / 0
P03372	Estrogen receptor	NR3A1	C00019560 C00034452	1 / 1
P43220	Glucagon-like peptide 1 receptor	Glucagon-like peptide receptor	C00001076 C00003841	0 / 0
P00918	Carbonic anhydrase 2	Lyase	C00001418 C00019560	1 / 2
Q13148	TAR DNA-binding protein 43	Unclassified protein	C00001076 C00003841	1 / 1
P84022	Mothers against decapentaplegic homolog 3	Unclassified protein	C00034452 C00048498	2 / 0
P11509	Cytochrome P450 2A6	Cytochrome P450 2A6	C00019560 C00034452	0 / 0
P33765	Adenosine receptor A3	Adenosine receptor	C00003841 C00019560	0 / 0
Q9UNA4	DNA polymerase iota	Enzyme	C00003841	0 / 0
P08912	Muscarinic acetylcholine receptor M5	Acetylcholine receptor	C00019560	0 / 0
P18825	Alpha-2C adrenergic receptor	Adrenergic receptor	C00019560	0 / 0
P13945	Beta-3 adrenergic receptor	Adrenergic receptor	C00019560	0 / 0
P08183	Multidrug resistance protein 1	drug	C00001076	1 / 0
P25024	C-X-C chemokine receptor type 1	CXC chemokine receptor	C00019560	0 / 0
P06241	Tyrosine-protein kinase Fyn	Src	C00019560	0 / 0
Q08209	Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform	Ser_Thr	C00019560	0 / 0
P11712	Cytochrome P450 2C9	Cytochrome P450 2C9	C00019560	0 / 1
Q00535	Cyclin-dependent kinase 5	Cdk5	C00001418	0 / 0
Q15078	Cyclin-dependent kinase 5 activator 1	REG serine/threonine protein kinase family	C00001418	0 / 0
Q9NR56	Muscleblind-like protein 1	Unclassified protein	C00001076	1 / 0
P00533	Epidermal growth factor receptor	TK tyrosine-protein kinase EGFR subfamily	C00019560	1 / 8
P11473	Vitamin D3 receptor	NR1I1	C00000931	2 / 3
P14416	D(2) dopamine receptor	Dopamine receptor	C00019560	2 / 0
P23219	Prostaglandin G/H synthase 1	Oxidoreductase	C00019560	0 / 0
P37288	Vasopressin V1a receptor	Vasopressin and oxytocin receptor	C00019560	0 / 0
P41145	Kappa-type opioid receptor	Opioid receptor	C00019560	0 / 0
Q9Y271	Cysteinyl leukotriene receptor 1	Leukotriene receptor	C00019560	0 / 0
P29274	Adenosine receptor A2a	Adenosine receptor	C00019560	0 / 0
P23280	Carbonic anhydrase 6	Lyase	C00001418	0 / 0
P25929	Neuropeptide Y receptor type 1	Neuropeptide Y receptor	C00019560	0 / 0
P50052	Type-2 angiotensin II receptor	Angiotensin receptor	C00019560	1 / 1
P17948	Vascular endothelial growth factor receptor 1	Vegfr	C00019560	0 / 0
P41968	Melanocortin receptor 3	Melanocortin receptor	C00019560	1 / 0
P35367	Histamine H1 receptor	Histamine receptor	C00019560	0 / 0
P25021	Histamine H2 receptor	Histamine receptor	C00019560	0 / 0
P14902	Indoleamine 2,3-dioxygenase 1	Enzyme	C00034452	0 / 0
Q92830	Histone acetyltransferase KAT2A	Enzyme	C00001076	0 / 0
P21397	Amine oxidase [flavin-containing] A	Oxidoreductase	C00019560	1 / 1
P07550	Beta-2 adrenergic receptor	Adrenergic receptor	C00019560	0 / 1
P04035	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Oxidoreductase	C00019560	0 / 0
P08913	Alpha-2A adrenergic receptor	Adrenergic receptor	C00019560	0 / 0
P21917	D(4) dopamine receptor	Dopamine receptor	C00019560	0 / 0
P30988	Calcitonin receptor	Calcitonin receptor	C00019560	0 / 0
P35462	D(3) dopamine receptor	Dopamine receptor	C00019560	1 / 0
P41143	Delta-type opioid receptor	Opioid receptor	C00019560	0 / 0
Q92731	Estrogen receptor beta	NR3A2	C00019560	0 / 1
P41595	5-hydroxytryptamine receptor 2B	Serotonin receptor	C00019560	0 / 0
P25101	Endothelin-1 receptor	Endothelin receptor	C00019560	0 / 0
P30411	B2 bradykinin receptor	Bradykinin receptor	C00019560	0 / 0
P10145	Interleukin-8	Secreted protein	C00034452	0 / 0
P32245	Melanocortin receptor 4	Melanocortin receptor	C00019560	1 / 0
P00915	Carbonic anhydrase 1	Lyase	C00001418	0 / 0
P32238	Cholecystokinin receptor type A	Cholecystokinin receptor	C00019560	0 / 0
P08311	Cathepsin G	S1A	C00019560	0 / 0
Q99720	Sigma non-opioid intracellular receptor 1	Membrane receptor	C00019560	1 / 0
P19793	Retinoic acid receptor RXR-alpha	NR2B1	C00000823	0 / 0
P03956	Interstitial collagenase	M10A	C00019560	0 / 1
P32241	Vasoactive intestinal polypeptide receptor 1	Vasoactive intestinal peptide receptor	C00019560	0 / 0
P47989	Xanthine dehydrogenase/oxidase	Oxidoreductase	C00001076	1 / 1
O75604	Ubiquitin carboxyl-terminal hydrolase 2	Enzyme	C00003936	0 / 0
Q13526	Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1	Enzyme	C00001076	0 / 0
P08172	Muscarinic acetylcholine receptor M2	Acetylcholine receptor	C00019560	2 / 0
P11229	Muscarinic acetylcholine receptor M1	Acetylcholine receptor	C00019560	0 / 0
P14679	Tyrosinase	Oxidoreductase	C00034452	4 / 2
P21554	Cannabinoid receptor 1	Cannabinoid receptor	C00019560	0 / 0
P31645	Sodium-dependent serotonin transporter	Serotonin	C00019560	2 / 0
P37231	Peroxisome proliferator-activated receptor gamma	NR1C3	C00001076	5 / 3
P04626	Receptor tyrosine-protein kinase erbB-2	TK tyrosine-protein kinase EGFR subfamily	C00019560	5 / 9
P20309	Muscarinic acetylcholine receptor M3	Acetylcholine receptor	C00019560	1 / 0
P21452	Substance-K receptor	Neurokinin receptor	C00019560	0 / 0
P55263	Adenosine kinase	Enzyme	C00001418	1 / 0
P51679	C-C chemokine receptor type 4	CC chemokine receptor	C00019560	0 / 0
P51681	C-C chemokine receptor type 5	CC chemokine receptor	C00019560	3 / 0
P50406	5-hydroxytryptamine receptor 6	Serotonin receptor	C00019560	0 / 0
Q96RI1	Bile acid receptor	NR1H4	C00000853	0 / 0
P41597	C-C chemokine receptor type 2	CC chemokine receptor	C00019560	1 / 0
P14780	Matrix metalloproteinase-9	M10A	C00019560	2 / 2
P08575	Receptor-type tyrosine-protein phosphatase C	Enzyme	C00019560	2 / 1
P05177	Cytochrome P450 1A2	Cytochrome P450 1A2	C00019560	0 / 0
P27361	Mitogen-activated protein kinase 3	Erk	C00019560	0 / 0
Q9UNQ0	ATP-binding cassette sub-family G member 2	ATP binding cassette	C00001076	2 / 0
P15428	15-hydroxyprostaglandin dehydrogenase [NAD(+)]	Enzyme	C00001076	2 / 2
P17252	Protein kinase C alpha type	Alpha	C00019560	0 / 0
P29466	Caspase-1	C14	C00019560	0 / 0
Q9Y4X1	UDP-glucuronosyltransferase 2A1	Enzyme	C00003047	0 / 0
O76074	cGMP-specific 3',5'-cyclic phosphodiesterase	PDE_5A	C00019560	0 / 0
P49146	Neuropeptide Y receptor type 2	Neuropeptide Y receptor	C00019560	0 / 0
P08588	Beta-1 adrenergic receptor	Adrenergic receptor	C00019560	1 / 0
P22303	Acetylcholinesterase	Hydrolase	C00019560	1 / 0
P28223	5-hydroxytryptamine receptor 2A	Serotonin receptor	C00019560	0 / 0
P28335	5-hydroxytryptamine receptor 2C	Serotonin receptor	C00019560	0 / 0
P35372	Mu-type opioid receptor	Opioid receptor	C00019560	0 / 0
P08173	Muscarinic acetylcholine receptor M4	Acetylcholine receptor	C00019560	0 / 0
P25103	Substance-P receptor	Neurokinin receptor	C00019560	0 / 0
P25105	Platelet-activating factor receptor	PAF receptor	C00019560	0 / 0
P33032	Melanocortin receptor 5	Melanocortin receptor	C00019560	0 / 0
Q16539	Mitogen-activated protein kinase 14	p38	C00019560	0 / 0
P33261	Cytochrome P450 2C19	Cytochrome P450 2C19	C00019560	1 / 1
P08246	Neutrophil elastase	S1A	C00019560	2 / 1
P05181	Cytochrome P450 2E1	Cytochrome P450 2E1	C00019560	0 / 0
Q01959	Sodium-dependent dopamine transporter	Dopamine	C00019560	1 / 0
P22309	UDP-glucuronosyltransferase 1-1	Enzyme	C00003047	5 / 1
Q12809	Potassium voltage-gated channel subfamily H member 2	KCNH, Kv10-12.x (Ether-a-go-go)	C00019560	2 / 2
P10635	Cytochrome P450 2D6	Cytochrome P450 2D6	C00019560	1 / 0
P10275	Androgen receptor	NR3C4	C00048438	3 / 4
P23975	Sodium-dependent noradrenaline transporter	Norepinephrine	C00019560	1 / 1
P25100	Alpha-1D adrenergic receptor	Adrenergic receptor	C00019560	0 / 0
P30542	Adenosine receptor A1	Adenosine receptor	C00019560	0 / 0
P18089	Alpha-2B adrenergic receptor	Adrenergic receptor	C00019560	0 / 0
P24557	Thromboxane-A synthase	Cytochrome P450 5A1	C00019560	1 / 1
P06239	Tyrosine-protein kinase Lck	Src	C00019560	0 / 1
P25025	C-X-C chemokine receptor type 2	CXC chemokine receptor	C00019560	0 / 0
P23141	Liver carboxylesterase 1	Enzyme	C00001418	0 / 0
P22748	Carbonic anhydrase 4	Lyase	C00001418	1 / 1
B2RXH2	Lysine-specific demethylase 4E	Enzyme	C00001076	0 / 0
P21728	D(1A) dopamine receptor	Dopamine receptor	C00019560	0 / 0
Q9NUW8	Tyrosyl-DNA phosphodiesterase 1	Enzyme	C00002663	1 / 1
O94956	Solute carrier organic anion transporter family member 2B1	Unclassified protein	C00001076	0 / 0
P04637	Cellular tumor antigen p53	Transcription Factor	C00000823	7 / 37
P05107	Integrin beta-2	Membrane receptor	C00001418	1 / 1
P05362	Intercellular adhesion molecule 1	Adhesion	C00001418	1 / 2
P20701	Integrin alpha-L	Membrane receptor	C00001418	0 / 0
Q13748	Tubulin alpha-3C/D chain	Structural	C00003936	0 / 0
P68366	Tubulin alpha-4A chain	Structural	C00003936	0 / 0
Q9H4B7	Tubulin beta-1 chain	Structural	C00003936	1 / 0
P04350	Tubulin beta-4A chain	Structural	C00003936	2 / 0
Q3ZCM7	Tubulin beta-8 chain	Structural	C00003936	0 / 0
P07437	Tubulin beta chain	Structural	C00003936	0 / 0
Q71U36	Tubulin alpha-1A chain	Structural	C00003936	1 / 1
P68371	Tubulin beta-4B chain	Structural	C00003936	0 / 0
Q13509	Tubulin beta-3 chain	Structural	C00003936	2 / 1
P49840	Glycogen synthase kinase-3 alpha	Gsk	C00001418	0 / 0
P49841	Glycogen synthase kinase-3 beta	Gsk	C00001418	0 / 0
P22310	UDP-glucuronosyltransferase 1-4	Enzyme	C00003047	3 / 0
P68363	Tubulin alpha-1B chain	Unclassified protein	C00003936	0 / 0
Q13885	Tubulin beta-2A chain	Structural	C00003936	0 / 0
Q6PEY2	Tubulin alpha-3E chain	Unclassified protein	C00003936	0 / 0
Q9BQE3	Tubulin alpha-1C chain	Unclassified protein	C00003936	0 / 0
Q9BUF5	Tubulin beta-6 chain	Structural	C00003936	0 / 0
Q9BVA1	Tubulin beta-2B chain	Structural	C00003936	1 / 0

268 Gene in CTD interactions

gene	gene name	gene description	KNApSAcK metabolite in interactions
1543	CYP1A1, AHH, AHRR, CP11, CYP1, P1-450, P450-C, P450DX	cytochrome P450, family 1, subfamily A, polypeptide 1 (EC:1.14.14.1)	C00000823 C00001076 C00003047
2729	GCLC, GCL, GCS, GLCL, GLCLC	glutamate-cysteine ligase, catalytic subunit (EC:6.3.2.2)	C00003047 C00019560 C00048438
7124	TNF, DIF, TNF-alpha, TNFA, TNFSF2	tumor necrosis factor	C00019560 C00048304 C00048438
3162	HMOX1, HMOX1D, HO-1, HSP32, bK286B10	heme oxygenase (decycling) 1 (EC:1.14.99.3)	C00000823 C00019560 C00048438
207	AKT1, AKT, CWS6, PKB, PKB-ALPHA, PRKBA, RAC, RAC-ALPHA	v-akt murine thymoma viral oncogene homolog 1 (EC:2.7.11.1)	C00000861 C00003047 C00019560
217	ALDH2, ALDH-E2, ALDHI, ALDM	aldehyde dehydrogenase 2 family (mitochondrial) (EC:1.2.1.3)	C00000357 C00019560 C00034452
7157	TP53, BCC7, LFS1, P53, TRP53	tumor protein p53	C00000357 C00000823 C00003047
125	ADH1B, ADH2	alcohol dehydrogenase 1B (class I), beta polypeptide (EC:1.1.1.1)	C00019560 C00048438
131	ADH7, ADH4	alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide (EC:1.1.1.1)	C00019560 C00048438
127	ADH4, ADH-2	alcohol dehydrogenase 4 (class II), pi polypeptide (EC:1.1.1.1)	C00019560 C00048438
126	ADH1C, ADH3	alcohol dehydrogenase 1C (class I), gamma polypeptide (EC:1.1.1.1)	C00019560 C00048438
231	AKR1B1, ADR, ALDR1, ALR2, AR	aldo-keto reductase family 1, member B1 (aldose reductase) (EC:1.1.1.21)	C00000357 C00048438
4852	NPY, PYY4	neuropeptide Y	C00000823 C00003047
218	ALDH3A1, ALDH3, ALDHIII	aldehyde dehydrogenase 3 family, member A1 (EC:1.2.1.5)	C00000357 C00034452
221	ALDH3B1, ALDH4, ALDH7	aldehyde dehydrogenase 3 family, member B1 (EC:1.2.1.5)	C00000357 C00034452
2512	FTL, NBIA3	ferritin, light polypeptide	C00019560 C00048438
4609	MYC, MRTL, MYCC, bHLHe39, c-Myc	v-myc avian myelocytomatosis viral oncogene homolog	C00000357 C00003047
124	ADH1A, ADH1	alcohol dehydrogenase 1A (class I), alpha polypeptide (EC:1.1.1.1)	C00019560 C00048438
2688	GH1, GH, GH-N, GHN, IGHD1B, hGH-N	growth hormone 1	C00019560 C00048438
596	BCL2, Bcl-2, PPP1R50	B-cell CLL/lymphoma 2	C00000823 C00019560
3678	ITGA5, CD49e, FNRA, VLA5A	integrin, alpha 5 (fibronectin receptor, alpha polypeptide)	C00019560 C00048304
2263	FGFR2, BBDS, BEK, BFR-1, CD332, CEK3, CFD1, ECT1, JWS, K-SAM, KGFR, TK14, TK25	fibroblast growth factor receptor 2 (EC:2.7.10.1)	C00019560 C00048304
1571	CYP2E1, CPE1, CYP2E, P450-J, P450C2E	cytochrome P450, family 2, subfamily E, polypeptide 1 (EC:1.14.13.n7)	C00019560 C00048304
595	CCND1, BCL1, D11S287E, PRAD1, U21B31	cyclin D1	C00019560 C00048304
847	CAT	catalase (EC:1.11.1.6)	C00019560 C00048304
4790	NFKB1, EBP-1, KBF1, NF-kB1, NF-kappa-B, NF-kappaB, NFKB-p105, NFKB-p50, NFkappaB, p105, p50	nuclear factor of kappa light polypeptide gene enhancer in B-cells 1	C00003047 C00019560
3725	JUN, AP-1, AP1, c-Jun	jun proto-oncogene	C00003047 C00048438
3156	HMGCR, LDLCQ3	3-hydroxy-3-methylglutaryl-CoA reductase (EC:1.1.1.34)	C00003047 C00019560
5594	MAPK1, ERK, ERK2, ERT1, MAPK2, P42MAPK, PRKM1, PRKM2, p38, p40, p41, p41mapk	mitogen-activated protein kinase 1 (EC:2.7.11.24)	C00019560 C00048438
1956	EGFR, ERBB, ERBB1, HER1, PIG61, mENA	epidermal growth factor receptor (EC:2.7.10.1)	C00003047 C00019560
2335	FN1, CIG, ED-B, FINC, FN, FNZ, GFND, GFND2, LETS, MSF	fibronectin 1	C00003047 C00019560
6783	SULT1E1, EST, EST-1, ST1E1, STE	sulfotransferase family 1E, estrogen-preferring, member 1 (EC:2.8.2.4)	C00019560
1906	EDN1, ET1, HDLCQ7, PPET1	endothelin 1	C00003047
1509	CTSD, CLN10, CPSD	cathepsin D (EC:3.4.23.5)	C00003047
3297	HSF1, HSTF1	heat shock transcription factor 1	C00003047
3320	HSP90AA1, EL52, HSP86, HSP89A, HSP90A, HSP90N, HSPC1, HSPCA, HSPCAL1, HSPCAL4, HSPN, Hsp89, Hsp90, LAP2	heat shock protein 90kDa alpha (cytosolic), class A member 1	C00003047
3308	HSPA4, APG-2, HS24/P52, HSPH2, RY, hsp70, hsp70RY	heat shock 70kDa protein 4	C00003047
3316	HSPB2, HSP27, Hs.78846, LOH11CR1K, MKBP	heat shock 27kDa protein 2	C00003047
3398	ID2, GIG8, ID2A, ID2H, bHLHb26	inhibitor of DNA binding 2, dominant negative helix-loop-helix protein	C00003047
3638	INSIG1, CL-6, CL6	insulin induced gene 1	C00003047
1447	CSN2, CASB	casein beta	C00003047
8850	KAT2B, CAF, P, P/CAF, PCAF	K(lysine) acetyltransferase 2B (EC:2.3.1.48)	C00003047
4193	MDM2, ACTFS, HDMX, hdm2	MDM2 oncogene, E3 ubiquitin protein ligase	C00003047
1030	CDKN2B, CDK4I, INK4B, MTS2, P15, TP15, p15INK4b	cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)	C00003047
100124292			C00003047
7295	TXN, TRDX, TRX, TRX1	thioredoxin	C00003047
7471	WNT1, BMND16, INT1, OI15	wingless-type MMTV integration site family, member 1	C00003047
26118	WSB1, SWIP1, WSB-1	WD repeat and SOCS box containing 1	C00003047
196	AHR, bHLHe76	aryl hydrocarbon receptor	C00001418
405	ARNT, HIF-1-beta, HIF-1beta, HIF1-beta, HIF1B, HIF1BETA, TANGO, bHLHe2	aryl hydrocarbon receptor nuclear translocator	C00001418
4157	MC1R, CMM5, MSH-R, SHEP2	melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor)	C00001418
4159	MC3R, BMIQ9, MC3, MC3-R, OB20, OQTL	melanocortin 3 receptor	C00001418
4160	MC4R	melanocortin 4 receptor	C00001418
4161	MC5R, MC2	melanocortin 5 receptor	C00001418
1028	CDKN1C, BWCR, BWS, KIP2, WBS, p57, p57Kip2	cyclin-dependent kinase inhibitor 1C (p57, Kip2)	C00003047
1027	CDKN1B, CDKN4, KIP1, MEN1B, MEN4, P27KIP1	cyclin-dependent kinase inhibitor 1B (p27, Kip1)	C00003047
1559	CYP2C9, CPC9, CYP2C, CYP2C10, CYPIIC9, P450IIC9	cytochrome P450, family 2, subfamily C, polypeptide 9 (EC:1.14.13.48 1.14.13.49 1.14.13.80)	C00048304
1026	CDKN1A, CAP20, CDKN1, CIP1, MDA-6, P21, SDI1, WAF1, p21CIP1	cyclin-dependent kinase inhibitor 1A (p21, Cip1)	C00003047
330	BIRC3, AIP1, API2, CIAP2, HAIP1, HIAP1, MALT2, MIHC, RNF49, c-IAP2	baculoviral IAP repeat containing 3	C00003047
3596	IL13, IL-13, P600	interleukin 13	C00048304
3565	IL4, BCGF-1, BCGF1, BSF-1, BSF1, IL-4	interleukin 4	C00048304
3567	IL5, EDF, IL-5, TRF	interleukin 5 (colony-stimulating factor, eosinophil)	C00048304
329	BIRC2, API1, HIAP2, Hiap-2, MIHB, RNF48, c-IAP1, cIAP1	baculoviral IAP repeat containing 2	C00003047
1386	ATF2, CRE-BP1, CREB2, HB16, TREB7	activating transcription factor 2 (EC:2.3.1.48)	C00003047
23536	ADAT1, HADAT1	adenosine deaminase, tRNA-specific 1 (EC:3.5.4.34)	C00019560
1646	AKR1C2, AKR1C-pseudo, BABP, DD, DD2, DDH2, HAKRD, HBAB, MCDR2, SRXY8	aldo-keto reductase family 1, member C2 (EC:1.3.1.20 1.1.1.357)	C00003047
501	ALDH7A1, ATQ1, EPD, PDE	aldehyde dehydrogenase 7 family, member A1 (EC:1.2.1.3 1.2.1.8 1.2.1.31)	C00000357
4316	MMP7, MMP-7, MPSL1, PUMP-1	matrix metallopeptidase 7 (matrilysin, uterine) (EC:3.4.24.23)	C00001076
1545	CYP1B1, CP1B, CYPIB1, GLC3A, P4501B1	cytochrome P450, family 1, subfamily B, polypeptide 1 (EC:1.14.14.1)	C00001076
128	ADH5, ADH-3, ADHX, FALDH, FDH, GSH-FDH, GSNOR	alcohol dehydrogenase 5 (class III), chi polypeptide (EC:1.1.1.1 1.1.1.284)	C00019560
1544	CYP1A2, CP12, P3-450, P450(PA)	cytochrome P450, family 1, subfamily A, polypeptide 2 (EC:1.14.14.1)	C00001076
22977	AKR7A3, AFAR2	aldo-keto reductase family 7, member A3 (aflatoxin aldehyde reductase)	C00019560
273	AMPH, AMPH1	amphiphysin	C00019560
162	AP1B1, ADTB1, AP105A, BAM22, CLAPB2	adaptor-related protein complex 1, beta 1 subunit	C00019560
79065	ATG9A, APG9L1, MGD3208, mATG9	autophagy related 9A	C00019560
506	ATP5B, ATPMB, ATPSB	ATP synthase, H+ transporting, mitochondrial F1 complex, beta polypeptide (EC:3.6.3.14)	C00019560
581	BAX, BCL2L4	BCL2-associated X protein	C00019560
8678	BECN1, ATG6, VPS30, beclin1	beclin 1, autophagy related	C00019560
274	BIN1, AMPH2, AMPHL, SH3P9	bridging integrator 1	C00019560
708	C1QBP, GC1QBP, HABP1, SF2p32, gC1Q-R, gC1qR, p32	complement component 1, q subcomponent binding protein	C00019560
832	CAPZB, CAPB, CAPPB, CAPZ	capping protein (actin filament) muscle Z-line, beta	C00019560
836	CASP3, CPP32, CPP32B, SCA-1	caspase 3, apoptosis-related cysteine peptidase (EC:3.4.22.56)	C00019560
841	CASP8, ALPS2B, CAP4, Casp-8, FLICE, MACH, MCH5	caspase 8, apoptosis-related cysteine peptidase (EC:3.4.22.61)	C00019560
857	CAV1, BSCL3, CGL3, MSTP085, PPH3, VIP21, CAV	caveolin 1, caveolae protein, 22kDa	C00019560
83446	CCDC70	coiled-coil domain containing 70	C00019560
54535	CCHCR1, C6orf18, HCR, SBP	coiled-coil alpha-helical rod protein 1	C00019560
894	CCND2, KIAK0002	cyclin D2	C00019560
994	CDC25B	cell division cycle 25B (EC:3.1.3.48)	C00019560
55664	CDC37L1, CDC37B, HARC	cell division cycle 37-like 1	C00019560
1003	CDH5, 7B4, CD144	cadherin 5, type 2 (vascular endothelium)	C00019560
23552	CDK20, CCRK, CDCH, P42, PNQALRE	cyclin-dependent kinase 20 (EC:2.7.11.22)	C00019560
1050	CEBPA, C/EBP-alpha, CEBP	CCAAT/enhancer binding protein (C/EBP), alpha	C00019560
55165	CEP55, C10orf3, CT111, URCC6	centrosomal protein 55kDa	C00019560
1066	CES1, ACAT, CE-1, CEH, CES2, HMSE, HMSE1, PCE-1, REH, SES1, TGH, hCE-1	carboxylesterase 1 (EC:3.1.1.1 3.1.1.56)	C00019560
1138	CHRNA5, LNCR2	cholinergic receptor, nicotinic, alpha 5 (neuronal)	C00019560
1140	CHRNB1, ACHRB, CHRNB, CMS1D, CMS2A, SCCMS	cholinergic receptor, nicotinic, beta 1 (muscle)	C00019560
1191	CLU, APO-J, APOJ, CLI, CLU1, CLU2, KUB1, NA1/NA2, SGP-2, SGP2, SP-40, TRPM-2, TRPM2	clusterin	C00019560
1266	CNN3	calponin 3, acidic	C00019560
1278	COL1A2, OI4	collagen, type I, alpha 2	C00019560
1417	CRYBB3, CATCN2, CRYB3, CTRCT22	crystallin, beta B3	C00019560
1442	CSH1, CS-1, CSA, CSMT, PL, hCS-A	chorionic somatomammotropin hormone 1 (placental lactogen)	C00019560
1535	CYBA, p22-PHOX	cytochrome b-245, alpha polypeptide	C00019560
1536	CYBB, AMCBX2, CGD, GP91-1, GP91-PHOX, GP91PHOX, NOX2, p91-PHOX	cytochrome b-245, beta polypeptide	C00019560
54541	DDIT4, Dig2, REDD-1, REDD1	DNA-damage-inducible transcript 4	C00019560
10591	DNPH1, C6orf108, RCL, RP3-330M21.3, dJ330M21.3	2'-deoxynucleoside 5'-phosphate N-hydrolase 1	C00019560
1837	DTNA, D18S892E, DRP3, DTN, DTN-A, LVNC1	dystrobrevin, alpha	C00019560
338599	DUPD1, DUSP27, FMDSP	dual specificity phosphatase and pro isomerase domain containing 1 (EC:3.1.3.16 3.1.3.48)	C00019560
2023	ENO1, ENO1L1, MPB1, NNE, PPH	enolase 1, (alpha) (EC:4.2.1.11)	C00019560
10961	ERP29, C12orf8, ERp28, ERp31, PDI-DB, PDIA9	endoplasmic reticulum protein 29	C00019560
2099	ESR1, ER, ESR, ESRA, ESTRR, Era, NR3A1	estrogen receptor 1	C00019560
2177	FANCD2, FA-D2, FA4, FACD, FAD, FAD2, FANCD	Fanconi anemia, complementation group D2	C00019560
84261	FBXW9, Fbw9	F-box and WD repeat domain containing 9	C00019560
2348	FOLR1, FBP, FOLR	folate receptor 1 (adult)	C00019560
972	CD74, DHLAG, HLADG, II, Ia-GAMMA	CD74 molecule, major histocompatibility complex, class II invariant chain	C00001076
2526	FUT4, CD15, ELFT, FCT3A, FUC-TIV, FUTIV, LeX, SSEA-1	fucosyltransferase 4 (alpha (1,3) fucosyltransferase, myeloid-specific) (EC:2.4.1.-)	C00019560
2534	FYN, SLK, SYN, p59-FYN	FYN oncogene related to SRC, FGR, YES (EC:2.7.10.2)	C00019560
2670	GFAP	glial fibrillary acidic protein	C00019560
3265	HRAS, C-BAS/HAS, C-H-RAS, C-HA-RAS1, CTLO, H-RASIDX, HAMSV, HRAS1, K-RAS, N-RAS, RASH1	Harvey rat sarcoma viral oncogene homolog	C00000823
51031	GLOD4, C17orf25, HC71	glyoxalase domain containing 4	C00019560
2741	GLRA1, HKPX1, STHE	glycine receptor, alpha 1	C00019560
2932	GSK3B	glycogen synthase kinase 3 beta (EC:2.7.11.1 2.7.11.26)	C00019560
2944	GSTM1, GST1, GSTM1-1, GSTM1a-1a, GSTM1b-1b, GTH4, GTM1, H-B, MU, MU-1	glutathione S-transferase mu 1 (EC:2.5.1.18)	C00019560
2952	GSTT1	glutathione S-transferase theta 1 (EC:2.5.1.18)	C00019560
57817	HAMP, HEPC, HFE2B, LEAP1, PLTR	hepcidin antimicrobial peptide	C00019560
1839	HBEGF, DTR, DTS, DTSF, HEGFL	heparin-binding EGF-like growth factor	C00019560
3091	HIF1A, HIF-1A, HIF-1alpha, HIF1, HIF1-ALPHA, MOP1, PASD8, bHLHe78	hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)	C00019560
3181	HNRNPA2B1, HNRNPA2, HNRNPB1, HNRPA2, HNRPA2B1, HNRPB1, IBMPFD2, RNPA2, SNRPB1	heterogeneous nuclear ribonucleoprotein A2/B1	C00019560
3190	HNRNPK, CSBP, HNRPK, TUNP	heterogeneous nuclear ribonucleoprotein K	C00019560
3359	HTR3A, 5-HT-3, 5-HT3A, 5-HT3R, 5HT3R, HTR3	5-hydroxytryptamine (serotonin) receptor 3A, ionotropic	C00019560
9177	HTR3B, 5-HT3B	5-hydroxytryptamine (serotonin) receptor 3B, ionotropic	C00019560
27429	HTRA2, OMI, PARK13, PRSS25	HtrA serine peptidase 2 (EC:3.4.21.108)	C00019560
3383	ICAM1, BB2, CD54, P3.58	intercellular adhesion molecule 1	C00019560
3479	IGF1, IGF-I, IGF1A, IGFI	insulin-like growth factor 1 (somatomedin C)	C00019560
3486	IGFBP3, BP-53, IBP3	insulin-like growth factor binding protein 3	C00019560
3589	IL11, AGIF, IL-11	interleukin 11	C00019560
3553	IL1B, IL-1, IL1-BETA, IL1F2	interleukin 1, beta	C00019560
3576	IL8, CXCL8, GCP-1, GCP1, LECT, LUCT, LYNAP, MDNCF, MONAP, NAF, NAP-1, NAP1	interleukin 8	C00019560
3708	ITPR1, INSP3R1, IP3R, IP3R1, SCA15, SCA16, SCA29	inositol 1,4,5-trisphosphate receptor, type 1	C00019560
83999	KREMEN1, KREMEN, KRM1	kringle containing transmembrane protein 1	C00019560
3875	KRT18, CYK18, K18	keratin 18	C00019560
3856	KRT8, CARD2, CK-8, CK8, CYK8, K2C8, K8, KO	keratin 8	C00019560
3897	L1CAM, CAML1, CD171, HSAS, HSAS1, MASA, MIC5, N-CAM-L1, N-CAML1, NCAM-L1, S10, SPG1	L1 cell adhesion molecule	C00019560
4017	LOXL2, LOR2, WS9-14	lysyl oxidase-like 2 (EC:1.4.3.-)	C00019560
2950	GSTP1, DFN7, FAEES3, GST3, GSTP, PI	glutathione S-transferase pi 1 (EC:2.5.1.18)	C00000931
5595	MAPK3, ERK-1, ERK1, ERT2, HS44KDAP, HUMKER1A, P44ERK1, P44MAPK, PRKM3, p44-ERK1, p44-MAPK	mitogen-activated protein kinase 3 (EC:2.7.11.24)	C00019560
4144	MAT2A, MATA2, MATII, SAMS2	methionine adenosyltransferase II, alpha (EC:2.5.1.6)	C00019560
4148	MATN3, DIPOA, EDM5, HOA, OADIP, OS2	matrilin 3	C00019560
406931	MIR139, MIR139-3p, MIRN139	microRNA 139	C00019560
406987	MIR204, MIRN204, miRNA204	microRNA 204	C00019560
100126336	MIR208B, MIRN208B	microRNA 208b	C00019560
407018	MIR27A, MIR27, MIRN27A	microRNA 27a	C00019560
442894	MIR302B, MIRN302B	microRNA 302b	C00019560
693120	MIR33B, MIRN33B, hsa-mir-33b	microRNA 33b	C00019560
407040	MIR34A, MIRN34A, miRNA34A, mir-34	microRNA 34a	C00019560
442914	MIR369, MIR369-3, MIRN369, MIRN369-3, hsa-mir-369	microRNA 369	C00019560
442915	MIR370, MIRN370, hsa-mir-370	microRNA 370	C00019560
442918	MIR373, MIRN373, hsa-mir-373, miRNA373	microRNA 373	C00019560
494324	MIR375, MIRN375, hsa-mir-375, miRNA375	microRNA 375	C00019560
574451	MIR432, MIRN432, hsa-mir-432	microRNA 432	C00019560
619552	MIR483, MIRN483, hsa-mir-483	microRNA 483	C00019560
574450	MIR493, MIRN493, hsa-mir-493	microRNA 493	C00019560
574456	MIR497, MIRN497, hsa-mir-497	microRNA 497	C00019560
574472	MIR518F, MIRN518F	microRNA 518f	C00019560
574471	MIR523, MIRN523, hsa-mir-523	microRNA 523	C00019560
693191	MIR606, MIRN606, hsa-mir-606	microRNA 606	C00019560
724026	MIR656, MIRN656, hsa-mir-656	microRNA 656	C00019560
100126326	MIR936, MIRN936, hsa-mir-936	microRNA 936	C00019560
4313	MMP2, CLG4, CLG4A, MMP-II, MONA, TBE-1	matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase) (EC:3.4.24.24)	C00019560
4548	MTR, HMAG, MS, cblG	5-methyltetrahydrofolate-homocysteine methyltransferase (EC:2.1.1.13)	C00019560
4595	MUTYH, CYP2C, MYH	mutY homolog (EC:3.2.2.-)	C00019560
4638	MYLK, AAT7, KRP, MLCK, MLCK1, MLCK108, MLCK210, MSTP083, MYLK1, smMLCK	myosin light chain kinase (EC:2.7.11.18)	C00019560
653361	NCF1, NCF1A, NOXO2, SH3PXD1A, p47phox	neutrophil cytosolic factor 1	C00019560
4688	NCF2, NCF-2, NOXA2, P67-PHOX, P67PHOX	neutrophil cytosolic factor 2	C00019560
4780	NFE2L2, NRF2	nuclear factor, erythroid 2-like 2	C00019560
4791	NFKB2, H2TF1, LYT-10, LYT10, NF-kB2, p105, p52	nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)	C00019560
4830	NME1, AWD, GAAD, NB, NBS, NDKA, NDPK-A, NDPKA, NM23, NM23-H1	NME/NM23 nucleoside diphosphate kinase 1 (EC:2.7.4.6)	C00019560
8996	NOL3, ARC, FCM, MYP, NOP, NOP30	nucleolar protein 3 (apoptosis repressor with CARD domain)	C00019560
4843	NOS2, HEP-NOS, INOS, NOS, NOS2A	nitric oxide synthase 2, inducible (EC:1.14.13.39)	C00019560
4854	NOTCH3, CADASIL, CASIL, IMF2	notch 3	C00019560
27035	NOX1, GP91-2, MOX1, NOH-1, NOH1	NADPH oxidase 1	C00019560
4897	NRCAM	neuronal cell adhesion molecule	C00019560
8829	NRP1, BDCA4, CD304, NP1, NRP, VEGF165R	neuropilin 1	C00019560
100506658	OCLN, BLCPMG	occludin (EC:2.1.1.67)	C00019560
4968	OGG1, HMMH, HOGG1, MUTM, OGH1	8-oxoguanine DNA glycosylase (EC:4.2.99.18)	C00019560
4986	OPRK1, K-OR-1, KOR, KOR-1, OPRK	opioid receptor, kappa 1	C00019560
4988	OPRM1, LMOR, M-OR-1, MOP, MOR, MOR1, OPRM	opioid receptor, mu 1	C00019560
84876	ORAI1, CRACM1, IMD9, ORAT1, TMEM142A	ORAI calcium release-activated calcium modulator 1	C00019560
142	PARP1, ADPRT, ADPRT_1, ADPRT1, ARTD1, PARP, PARP-1, PPOL, pADPRT-1	poly (ADP-ribose) polymerase 1 (EC:2.4.2.30)	C00019560
5142	PDE4B, DPDE4, PDE4B5, PDEIVB	phosphodiesterase 4B, cAMP-specific (EC:3.1.4.17)	C00019560
5173	PDYN, ADCA, PENKB, SCA23	prodynorphin	C00019560
5179	PENK	proenkephalin	C00019560
5204	PFDN5, MM-1, MM1, PFD5	prefoldin subunit 5	C00019560
25796	PGLS, 6PGL	6-phosphogluconolactonase (EC:3.1.1.31)	C00019560
5245	PHB, PHB1	prohibitin	C00019560
26227	PHGDH, 3-PGDH, 3PGDH, PDG, PGAD, PGD, PGDH, SERA	phosphoglycerate dehydrogenase (EC:1.1.1.95)	C00019560
5335	PLCG1, NCKAP3, PLC-II, PLC1, PLC148, PLCgamma1	phospholipase C, gamma 1 (EC:3.1.4.11)	C00019560
5352	PLOD2, LH2, TLH	procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 (EC:1.14.11.4)	C00019560
57048	PLSCR3	phospholipid scramblase 3	C00019560
5366	PMAIP1, APR, NOXA	phorbol-12-myristate-13-acetate-induced protein 1	C00019560
5395	PMS2, HNPCC4, PMS2CL, PMSL2	PMS2 postmeiotic segregation increased 2 (S. cerevisiae)	C00019560
5426	POLE, CRCS12, FILS, POLE1	polymerase (DNA directed), epsilon, catalytic subunit (EC:2.7.7.7)	C00019560
5443	POMC, ACTH, CLIP, LPH, MSH, NPP, POC	proopiomelanocortin	C00019560
5451	POU2F1, OCT1, OTF1, oct-1B	POU class 2 homeobox 1	C00019560
5460	POU5F1, OCT3, OCT4, OTF-3, OTF3, OTF4, Oct-3, Oct-4	POU class 5 homeobox 1	C00019560
5465	PPARA, NR1C1, PPAR, PPARalpha, hPPAR	peroxisome proliferator-activated receptor alpha	C00019560
100136658			C00019560
5468	PPARG, CIMT1, GLM1, NR1C3, PPARG1, PPARG2, PPARgamma	peroxisome proliferator-activated receptor gamma	C00019560
8497	PPFIA4	protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 4	C00019560
5052	PRDX1, MSP23, NKEF-A, NKEFA, PAG, PAGA, PAGB, PRX1, PRXI, TDPX2	peroxiredoxin 1 (EC:1.11.1.15)	C00019560
9588	PRDX6, 1-Cys, AOP2, NSGPx, PRX, aiPLA2, p29	peroxiredoxin 6 (EC:1.11.1.9 1.11.1.15)	C00019560
5578	PRKCA, AAG6, PKC-alpha, PKCA, PRKACA	protein kinase C, alpha (EC:2.7.11.13)	C00019560
5579	PRKCB, PKC-beta, PKCB, PRKCB1, PRKCB2	protein kinase C, beta (EC:2.7.11.13)	C00019560
5580	PRKCD, MAY1, PKCD, nPKC-delta	protein kinase C, delta (EC:2.7.10.2 2.7.11.13)	C00019560
5743	PTGS2, COX-2, COX2, GRIPGHS, PGG/HS, PGHS-2, PHS-2, hCox-2	prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) (EC:1.14.99.1)	C00019560
2185	PTK2B, CADTK, CAKB, FADK2, FAK2, PKB, PTK, PYK2, RAFTK	protein tyrosine kinase 2 beta (EC:2.7.10.2)	C00019560
5879	RAC1, Rac-1, TC-25, p21-Rac1	ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)	C00019560
5884	RAD17, CCYC, HRAD17, R24L, RAD17SP, RAD24	RAD17 homolog (S. pombe)	C00019560
5970	RELA, NFKB3, p65	v-rel avian reticuloendotheliosis viral oncogene homolog A	C00019560
6236	RRAD, RAD, RAD1, REM3	Ras-related associated with diabetes	C00019560
6275	S100A4, 18A2, 42A, CAPL, FSP1, MTS1, P9KA, PEL98	S100 calcium binding protein A4	C00019560
6342	SCP2, NLTP, NSL-TP, SCP-2, SCP-CHI, SCP-X, SCPX	sterol carrier protein 2 (EC:2.3.1.176)	C00019560
23513	SCRIB, CRIB1, SCRB1, SCRIB1, Vartul	scribbled planar cell polarity protein	C00019560
6573	SLC19A1, CHMD, FOLT, IFC1, REFC, RFC1	solute carrier family 19 (folate transporter), member 1	C00019560
2030	SLC29A1, ENT1	solute carrier family 29 (equilibrative nucleoside transporter), member 1	C00019560
60682	SMAP1, SMAP-1	small ArfGAP 1	C00019560
6678	SPARC, ON	secreted protein, acidic, cysteine-rich (osteonectin)	C00019560
6696	SPP1, BNSP, BSPI, ETA-1, OPN	secreted phosphoprotein 1	C00019560
6720	SREBF1, SREBP-1c, SREBP1, bHLHd1	sterol regulatory element binding transcription factor 1	C00019560
6723	SRM, PAPT, SPDSY, SPS1, SRML1	spermidine synthase (EC:2.5.1.16)	C00019560
56910	STARD7, GTT1	StAR-related lipid transfer (START) domain containing 7	C00019560
6786	STIM1, D11S4896E, GOK, IMD10, TAM	stromal interaction molecule 1	C00019560
6817	SULT1A1, HAST1/HAST2, P-PST, PST, ST1A1, ST1A3, STP, STP1, TSPST1	sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1 (EC:2.8.2.1)	C00019560
6818	SULT1A3, HAST, HAST3, M-PST, ST1A3/ST1A4, ST1A5, STM, TL-PST	sulfotransferase family, cytosolic, 1A, phenol-preferring, member 3 (EC:2.8.2.1)	C00019560
1647	GADD45A, DDIT1, GADD45	growth arrest and DNA-damage-inducible, alpha	C00003047
6822	SULT2A1, DHEA-ST, DHEAS, HST, ST2, ST2A1, ST2A3, STD, hSTa	sulfotransferase family, cytosolic, 2A, dehydroepiandrosterone (DHEA)-preferring, member 1 (EC:2.8.2.14)	C00019560
9095	TBX19, TBS19, TPIT, dJ747L4.1	T-box 19	C00019560
7037	TFRC, CD71, T9, TFR, TFR1, TR, TRFR, p90	transferrin receptor	C00019560
7040	TGFB1, CED, DPD1, LAP, TGFB, TGFbeta	transforming growth factor, beta 1	C00019560
7052	TGM2, G-ALPHA-h, GNAH, TG2, TGC	transglutaminase 2 (EC:2.3.2.13)	C00019560
7082	TJP1, ZO-1	tight junction protein 1	C00019560
7083	TK1, TK2	thymidine kinase 1, soluble (EC:2.7.1.21)	C00019560
7167	TPI1, TIM, TPI, TPID	triosephosphate isomerase 1 (EC:5.3.1.1)	C00019560
10107	TRIM10, HERF1, RFB30, RNF9	tripartite motif containing 10	C00019560
7422	VEGFA, MVCD1, VEGF, VPF	vascular endothelial growth factor A	C00019560
7498	XDH, XO, XOR	xanthine dehydrogenase (EC:1.17.1.4 1.17.3.2)	C00019560
331	XIAP, API3, BIRC4, IAP-3, ILP1, MIHA, XLP2, hIAP-3, hIAP3	X-linked inhibitor of apoptosis	C00019560
7515	XRCC1, RCC	X-ray repair complementing defective repair in Chinese hamster cells 1	C00019560
25925	ZNF521, EHZF, Evi3	zinc finger protein 521	C00019560
57016	AKR1B10, AKR1B11, AKR1B12, ALDRLn, ARL-1, ARL1, HIS, HSI	aldo-keto reductase family 1, member B10 (aldose reductase) (EC:1.1.1.2)	C00048438
1645	AKR1C1, 2-ALPHA-HSD, 20-ALPHA-HSD, C9, DD1, DD1/DD2, DDH, DDH1, H-37, HAKRC, HBAB, MBAB	aldo-keto reductase family 1, member C1 (EC:1.3.1.20 1.1.1.149 1.1.1.112)	C00048438
8644	AKR1C3, DD3, DDX, HA1753, HAKRB, HAKRe, HSD17B5, PGFS, hluPGFS	aldo-keto reductase family 1, member C3 (EC:1.3.1.20 1.1.1.188 1.1.1.239 1.1.1.64 1.1.1.112 1.1.1.357)	C00048438
6347	CCL2, GDCF-2, HC11, HSMCR30, MCAF, MCP-1, MCP1, SCYA2, SMC-CF	chemokine (C-C motif) ligand 2	C00048438
1135	CHRNA2	cholinergic receptor, nicotinic, alpha 2 (neuronal)	C00048438
1143	CHRNB4	cholinergic receptor, nicotinic, beta 4 (neuronal)	C00048438
2235	FECH, EPP, FCE	ferrochelatase (EC:4.99.1.1)	C00048438
2353	FOS, AP-1, C-FOS, p55	FBJ murine osteosarcoma viral oncogene homolog	C00048438
2539	G6PD, G6PD1	glucose-6-phosphate dehydrogenase (EC:1.1.1.49)	C00048438
2730	GCLM, GLCLR	glutamate-cysteine ligase, modifier subunit (EC:6.3.2.2)	C00048438
2936	GSR	glutathione reductase (EC:1.8.1.7)	C00048438
3033	HADH, HAD, HADH1, HADHSC, HCDH, HHF4, MSCHAD, SCHAD	hydroxyacyl-CoA dehydrogenase (EC:1.1.1.35)	C00048438
3569	IL6, BSF2, HGF, HSF, IFNB2, IL-6	interleukin 6 (interferon, beta 2)	C00048438
4097	MAFG, hMAF	v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog G	C00048438
4199	ME1, HUMNDME, MES	malic enzyme 1, NADP(+)-dependent, cytosolic (EC:1.1.1.40)	C00048438
1728	NQO1, DHQU, DIA4, DTD, NMOR1, NMORI, QR1	NAD(P)H dehydrogenase, quinone 1 (EC:1.6.5.2)	C00048438
5226	PGD, 6PGD	phosphogluconate dehydrogenase (EC:1.1.1.44)	C00048438
22949	PTGR1, LTB4DH, PGR1, ZADH3	prostaglandin reductase 1 (EC:1.3.1.48 1.3.1.74)	C00048438
140809	SRXN1, C20orf139, Npn3, SRX, SRX1	sulfiredoxin 1 (EC:1.8.98.2)	C00048438
7296	TXNRD1, GRIM-12, TR, TR1, TRXR1, TXNR	thioredoxin reductase 1 (EC:1.8.1.9)	C00048438

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Diseases related to proteins in ChEMBL interactions

Diseases related to CTD interactions