Orthosiphon stamineus
Species
KNApSAcK Entry
| Organism name | Orthosiphon stamineus |
|---|---|
| Genus | Orthosiphon |
| Family | Labiatae |
| Kingdom | Plantae |
NCBI taxonomy
Entry
| Linked NCBI taxonomy name | Orthosiphon stamineus |
|---|---|
| Linked NCBI taxonomy ID | 260636 |
| Linked level | species |
Family
| Family in NCBI taxonomy | Lamiaceae |
|---|---|
| ID | 4136 |
Kingdom (Superkingdom)
| Kingdom (Superkingdom) in NCBI taxonomy | Viridiplantae |
|---|---|
| ID | 33090 |
Plant class
| Plant class | asterids |
|---|---|
| ID | 71274 |
Metabolite list (56)
| KNApSAcK ID | name | ChEMBL link | CTD link |
# of proteins in
ChEMBL interaction / related OMIM / related KEGG DISEASE |
# of genes in
CTD interaction / related diseases |
KCF-S
cluster |
phytochemical
cluster |
figure |
|---|---|---|---|---|---|---|---|---|
C00003894
|
Eupatorin
/ 3',5-Dihydroxy-4',6,7-trimethoxyflavone / 5-Hydroxy-2-(3-hydroxy-4-methoxyphenyl)-6,7-dimethoxy-4H-1-benzopyran-4-one |
CHEMBL487402
|
C103110
|
5 / 5 / 4 | 5 / 0 | No. 3 | No. 15 |
|
|
C00003839
|
Ladanein
|
CHEMBL209257
|
No. 3 | No. 15 |
|
|||
|
C00003898
|
5-Hydroxy-6,7,3',4'-tetramethoxyflavone
/ 6-Hydroxyluteolin 6,7,3',4'-tetramethyl ether / 2-(3,4-Dimethoxyphenyl)-5-hydroxy-6,7-dimethoxy-4H-1-benzopyran-4-one |
CHEMBL226508
|
C045324
|
No. 8 | No. 15 |
|
||
|
C00013596
|
Sinensetin
/ Pedalitin permethyl ether / 5,6,7,3',4'-Pentamethoxyflavone / 2-(3,4-Dimethoxyphenyl)-5,6,7-trimethoxy-4H-1-benzopyran-4-one |
CHEMBL226507
|
C059295
|
7 / 6 / 7 | 3 / 0 | No. 8 | No. 15 |
|
|
C00003841
|
Tetramethylscutellarein
/ 5,6,7,4'-Tetramethoxyflavone / Scutellarein 5,6,7,4'-tetramethyl ether / 5,6,7-Trimethoxy-2-(4-methoxyphenyl)-4H-1-benzopyran-4-one |
CHEMBL75349
|
C072809
|
9 / 4 / 8 | No. 8 | No. 15 |
|
|
|
C00003896
|
6-Hydroxyluteolin 5,6,7,4'-tetramethyl ether
|
CHEMBL124885
|
2 / 4 / 4 | No. 8 | No. 15 |
|
||
|
C00019064
|
Oleanolic acid
/ Astrantiagenin C / Virgaureagenin B / 3beta-Hydroxyolean-12-en-28-oic acid |
CHEMBL56615
CHEMBL168 CHEMBL180553 CHEMBL365375 CHEMBL486382 CHEMBL1413646 CHEMBL1436454 |
D009828
|
30 / 8 / 12 | 21 / 15 | No. 13 | No. 51 |
|
|
C00003558
|
Ursolic acid
|
CHEMBL297810
CHEMBL56048 CHEMBL300594 CHEMBL169 CHEMBL176234 CHEMBL491715 CHEMBL1316667 CHEMBL1555307 CHEMBL1593360 CHEMBL1979720 |
C005466
|
47 / 26 / 33 | 15 / 12 | No. 13 | No. 51 |
|
|
C00003741
|
Betulinic acid
|
CHEMBL269277
CHEMBL71690 CHEMBL519059 CHEMBL1318530 CHEMBL2005635 |
C002070
|
34 / 17 / 14 | 10 / 2 | No. 23 | No. 51 |
|
|
C00003840
|
Salvigenin
|
CHEMBL376644
|
C014049
|
No. 35 | No. 15 |
|
||
|
C00003870
|
Luteolin 7,3',4'-trimethyl ether
/ 5-Hydroxy-7,3',4'-trimethoxyflavone / 2-(3,4-Dimethoxyphenyl)-5-hydroxy-7-methoxy-4H-1-benzopyran-4-one |
CHEMBL468876
|
No. 35 | No. 15 |
|
|||
|
C00013301
|
6-Hydroxy-5,7,4'-trimethoxyflavone
/ 6-Hydroxy-5,7-dimethoxy-2-(4-methoxyphenyl)-4H-1-benzopyran-4-one |
CHEMBL77695
|
No. 35 | No. 15 |
|
|||
|
C00003672
|
Sitosterol
/ beta-sitosterl / (-)-beta-Sitosterol / Stigmast-5-en-3beta-ol |
CHEMBL221542
CHEMBL1398443 CHEMBL1875388 |
17 / 19 / 12 | No. 53 | No. 11 |
|
||
|
C00032100
|
Orthosiphol M
/ (-)-Orthosiphol M |
CHEMBL450421
|
No. 160 |
|
||||
|
C00044981
|
Orthosiphol X
/ (-)-Orthosiphol X |
CHEMBL445290
|
No. 160 |
|
||||
|
C00044980
|
Orthosiphol W
/ (-)-Orthosiphol W |
CHEMBL448016
|
No. 160 |
|
||||
|
C00044979
|
Orthosiphol V
/ (-)-Orthosiphol V |
CHEMBL450248
|
No. 160 |
|
||||
|
C00031548
|
2-O-Deacetylorthosiphol J
/ (-)-2-O-Deacetylorthosiphol J |
No. 160 |
|
|||||
|
C00032066
|
Neoorthosiphol A
/ (-)-Neoorthosiphol A |
CHEMBL525987
|
No. 160 |
|
||||
|
C00032067
|
Neoorthosiphol B
/ (+)-Neoorthosiphol B |
No. 160 |
|
|||||
|
C00032079
|
Norstaminol A
/ (-)-Norstaminol A |
No. 160 |
|
|||||
|
C00032098
|
Orthosiphol H
/ (-)-Orthosiphol H |
No. 160 |
|
|||||
|
C00032099
|
Orthosiphol K
/ (-)-Orthosiphol K |
CHEMBL474466
|
No. 160 |
|
||||
|
C00046252
|
Orthosiphol L
/ (-)-Orthosiphol L |
CHEMBL503133
|
No. 160 |
|
||||
|
C00032101
|
Orthosiphol N
/ (-)-Orthosiphol N |
CHEMBL447217
|
No. 160 |
|
||||
|
C00032158
|
Siphonol A
/ (-)-Siphonol A |
CHEMBL420695
|
No. 160 |
|
||||
|
C00032159
|
Siphonol B
/ (-)-Siphonol B |
CHEMBL332637
|
No. 160 |
|
||||
|
C00032160
|
Siphonol C
/ (-)-Siphonol C |
CHEMBL333406
|
No. 160 |
|
||||
|
C00044977
|
Orthosiphol T
/ (-)-Orthosiphol T |
CHEMBL510297
|
No. 160 |
|
||||
|
C00032162
|
Siphonol E
/ (-)-Siphonol E |
CHEMBL117118
|
No. 160 |
|
||||
|
C00032197
|
Staminol A
/ (-)-Staminol A |
No. 160 |
|
|||||
|
C00032198
|
Staminol B
/ (-)-Staminol B |
No. 160 |
|
|||||
|
C00033272
|
Orthosiphol A
|
CHEMBL508620
|
No. 160 |
|
||||
|
C00033273
|
Orthosiphol B
|
CHEMBL509129
|
No. 160 |
|
||||
|
C00033274
|
Orthosiphol F
/ (-)-Orthosiphol F |
CHEMBL509450
|
No. 160 |
|
||||
|
C00033275
|
Orthosiphol G
/ (-)-Orthosiphol G |
CHEMBL448947
|
No. 160 |
|
||||
|
C00033276
|
Orthosiphol I
/ (-)-Orthosiphol I |
CHEMBL465222
|
No. 160 |
|
||||
|
C00033277
|
Orthosiphol J
/ (-)-Orthosiphol J |
CHEMBL502992
|
No. 160 |
|
||||
|
C00033278
|
Orthosiphonone A
/ (-)-Orthosiphonone A |
CHEMBL447412
|
No. 160 |
|
||||
|
C00033387
|
Staminolactone A
/ (-)-Staminolactone A |
No. 160 |
|
|||||
|
C00033388
|
Staminolactone B
/ (-)-Staminolactone B |
No. 160 |
|
|||||
|
C00035938
|
3-O-Deacetylorthosiphol I
/ (-)-3-O-Deacetylorthosiphol I |
No. 160 |
|
|||||
|
C00044978
|
Orthosiphol U
/ (-)-Orthosiphol U |
CHEMBL509005
|
No. 160 |
|
||||
|
C00044974
|
Orthosiphol D
|
CHEMBL448572
|
No. 160 |
|
||||
|
C00044975
|
Orthosiphol O
/ (-)-Orthosiphol O |
CHEMBL500763
|
No. 160 |
|
||||
|
C00044976
|
Orthosiphol R
/ (-)-Orthosiphol R |
CHEMBL508513
|
No. 160 |
|
||||
|
C00032161
|
Siphonol D
/ (-)-Siphonol D |
CHEMBL331893
|
No. 160 |
|
||||
|
C00002770
|
Rosmarinic acid
|
CHEMBL66966
CHEMBL324842 CHEMBL1315100 CHEMBL2111558 |
48 / 35 / 38 | No. 749 |
|
|||
|
C00000615
|
Caffeic acid
|
CHEMBL145
CHEMBL1320034 |
68 / 64 / 63 | No. 904 | No. 6 |
|
||
|
C00020778
|
Aurantiamide acetate
|
CHEMBL473971
|
C011670
|
No. 2605 |
|
|||
|
C00029834
|
Vomifoliol
/ Blumenol A / (+)-Blumenol A / Roseoside aglycon |
CHEMBL463088
|
No. 3492 |
|
||||
|
C00044983
|
Orthosiphol Z
/ (-)-Orthosiphol Z |
No. 4772 |
|
|||||
|
C00044982
|
Orthosiphol Y
/ (-)-Orthosiphol Y |
CHEMBL523730
|
No. 4772 |
|
||||
|
C00045070
|
Secoorthosiphol B
|
CHEMBL510190
|
No. 5565 |
|
||||
|
C00044973
|
Orthosiphol C
/ (-)-Orthosiphol C |
No. 5565 |
|
|||||
|
C00046212
|
Norstaminone A
|
CHEMBL472848
|
No. 6230 |
|
Human Protein / Gene in interactions
141 ChEMBL Protein in interactions
| accession | description | class description | KNApSAcK metabolite in interactions |
# of diseases
(OMIM / KEGG) |
|---|---|---|---|---|
| P06746 | DNA polymerase beta | Enzyme | C00000615 C00002770 C00003558 C00003672 C00003741 C00019064 | 0 / 0 |
| P33261 | Cytochrome P450 2C19 | Cytochrome P450 2C19 | C00000615 C00002770 C00003558 C00003672 C00003741 | 1 / 1 |
| P08684 | Cytochrome P450 3A4 | Cytochrome P450 3A4 | C00000615 C00002770 C00003558 C00003672 C00003741 | 0 / 1 |
| P11712 | Cytochrome P450 2C9 | Cytochrome P450 2C9 | C00000615 C00002770 C00003558 C00003672 C00003741 | 0 / 1 |
| P10635 | Cytochrome P450 2D6 | Cytochrome P450 2D6 | C00000615 C00002770 C00003558 C00003672 C00003741 | 1 / 0 |
| P15121 | Aldose reductase | Enzyme | C00000615 C00002770 C00003558 C00003741 C00019064 | 0 / 0 |
| P05177 | Cytochrome P450 1A2 | Cytochrome P450 1A2 | C00000615 C00002770 C00003558 C00003672 C00003741 | 0 / 0 |
| Q03164 | Histone-lysine N-methyltransferase 2A | Enzyme | C00000615 C00003558 C00003841 C00013596 | 1 / 2 |
| P18031 | Tyrosine-protein phosphatase non-receptor type 1 | Tyr | C00000615 C00003558 C00003672 C00019064 | 0 / 0 |
| P35354 | Prostaglandin G/H synthase 2 | Oxidoreductase | C00000615 C00002770 C00003558 C00019064 | 0 / 3 |
| O00255 | Menin | Unclassified protein | C00000615 C00003558 C00003841 C00013596 | 2 / 5 |
| Q92830 | Histone acetyltransferase KAT2A | Enzyme | C00002770 C00003558 C00013596 C00019064 | 0 / 0 |
| O75604 | Ubiquitin carboxyl-terminal hydrolase 2 | Enzyme | C00002770 C00003558 C00003741 C00019064 | 0 / 0 |
| O60218 | Aldo-keto reductase family 1 member B10 | Enzyme | C00000615 C00003558 C00003741 C00019064 | 0 / 0 |
| P27695 | DNA-(apurinic or apyrimidinic site) lyase | Enzyme | C00000615 C00002770 C00003558 C00019064 | 0 / 0 |
| P49841 | Glycogen synthase kinase-3 beta | Gsk | C00003558 C00003672 C00003741 C00019064 | 0 / 0 |
| Q9UBT6 | DNA polymerase kappa | Enzyme | C00000615 C00002770 C00003741 C00013596 | 0 / 0 |
| P23219 | Prostaglandin G/H synthase 1 | Oxidoreductase | C00000615 C00002770 C00003558 C00019064 | 0 / 0 |
| Q01196 | Runt-related transcription factor 1 | Unclassified protein | C00002770 C00003558 C00019064 | 1 / 4 |
| P19838 | Nuclear factor NF-kappa-B p105 subunit | Transcription Factor | C00000615 C00003558 C00003741 | 0 / 0 |
| Q96QE3 | ATPase family AAA domain-containing protein 5 | Unclassified protein | C00002770 C00003841 C00019064 | 0 / 0 |
| O94925 | Glutaminase kidney isoform, mitochondrial | Enzyme | C00000615 C00002770 C00003558 | 0 / 0 |
| Q9UNA4 | DNA polymerase iota | Enzyme | C00002770 C00003841 C00019064 | 0 / 0 |
| Q9NUW8 | Tyrosyl-DNA phosphodiesterase 1 | Enzyme | C00000615 C00002770 C00003672 | 1 / 1 |
| Q8TDU6 | G-protein coupled bile acid receptor 1 | Steroid-like ligand receptor | C00003558 C00003741 C00019064 | 0 / 0 |
| Q96RI1 | Bile acid receptor | NR1H4 | C00003558 C00003741 C00019064 | 0 / 0 |
| P02545 | Prelamin-A/C | Unclassified protein | C00000615 C00003558 C00003741 | 11 / 10 |
| Q13951 | Core-binding factor subunit beta | Unclassified protein | C00002770 C00003558 C00019064 | 0 / 1 |
| P83916 | Chromobox protein homolog 1 | Unclassified protein | C00002770 C00003558 C00019064 | 0 / 0 |
| P04798 | Cytochrome P450 1A1 | Cytochrome P450 1A1 | C00003894 C00003896 C00013596 | 0 / 0 |
| P10828 | Thyroid hormone receptor beta | NR1A2 | C00000615 C00002770 C00003558 | 3 / 1 |
| P51452 | Dual specificity protein phosphatase 3 | Ser_Thr_Tyr | C00000615 C00019064 | 0 / 0 |
| P17706 | Tyrosine-protein phosphatase non-receptor type 2 | Tyr | C00003558 C00019064 | 0 / 1 |
| P80365 | Corticosteroid 11-beta-dehydrogenase isozyme 2 | Enzyme | C00003558 C00003672 | 1 / 1 |
| P29350 | Tyrosine-protein phosphatase non-receptor type 6 | Tyr | C00003558 C00019064 | 0 / 0 |
| P16473 | Thyrotropin receptor | Glycohormone receptor | C00000615 C00003672 | 3 / 2 |
| P10636 | Microtubule-associated protein tau | Unclassified protein | C00000615 C00002770 | 4 / 3 |
| P10586 | Receptor-type tyrosine-protein phosphatase F | Receptor tyrosine-protein phosphatase | C00003558 C00019064 | 0 / 0 |
| P08047 | Transcription factor Sp1 | Unclassified protein | C00003558 C00003672 | 0 / 0 |
| P24666 | Low molecular weight phosphotyrosine protein phosphatase | Tyr | C00003558 C00019064 | 0 / 0 |
| O75164 | Lysine-specific demethylase 4A | Enzyme | C00000615 C00002770 | 0 / 0 |
| Q12794 | Hyaluronidase-1 | Enzyme | C00000615 C00002770 | 1 / 2 |
| P23469 | Receptor-type tyrosine-protein phosphatase epsilon | Receptor tyrosine-protein phosphatase | C00003558 C00019064 | 0 / 0 |
| Q06124 | Tyrosine-protein phosphatase non-receptor type 11 | Tyr | C00000615 C00019064 | 4 / 2 |
| B2RXH2 | Lysine-specific demethylase 4E | Enzyme | C00000615 C00002770 | 0 / 0 |
| P03372 | Estrogen receptor | NR3A1 | C00000615 C00003672 | 1 / 1 |
| P46063 | ATP-dependent DNA helicase Q1 | Enzyme | C00002770 C00003558 | 0 / 0 |
| Q96KQ7 | Histone-lysine N-methyltransferase EHMT2 | Enzyme | C00000615 C00002770 | 0 / 0 |
| P15428 | 15-hydroxyprostaglandin dehydrogenase [NAD(+)] | Enzyme | C00000615 C00002770 | 2 / 2 |
| P00352 | Retinal dehydrogenase 1 | Enzyme | C00000615 C00003841 | 0 / 0 |
| Q99714 | 3-hydroxyacyl-CoA dehydrogenase type-2 | Enzyme | C00000615 C00002770 | 3 / 3 |
| P10253 | Lysosomal alpha-glucosidase | Hydrolase | C00000615 C00002770 | 1 / 1 |
| P35236 | Tyrosine-protein phosphatase non-receptor type 7 | Tyr | C00000615 C00019064 | 0 / 0 |
| Q16665 | Hypoxia-inducible factor 1-alpha | Transcription Factor | C00000615 C00003741 | 0 / 0 |
| P18433 | Receptor-type tyrosine-protein phosphatase alpha | Receptor tyrosine-protein phosphatase | C00003558 C00019064 | 0 / 0 |
| Q13093 | Platelet-activating factor acetylhydrolase | Enzyme | C00000615 C00002770 | 3 / 0 |
| Q16678 | Cytochrome P450 1B1 | Cytochrome P450 1B1 | C00003894 C00003896 | 4 / 4 |
| O75874 | Isocitrate dehydrogenase [NADP] cytoplasmic | Enzyme | C00003558 C00003741 | 1 / 0 |
| P14679 | Tyrosinase | Oxidoreductase | C00000615 C00003672 | 4 / 2 |
| O75496 | Geminin | Unclassified protein | C00003741 C00019064 | 0 / 0 |
| P49798 | Regulator of G-protein signaling 4 | Unclassified protein | C00003672 C00003741 | 2 / 0 |
| P11511 | Cytochrome P450 19A1 | Cytochrome P450 19A1 | C00003558 C00019064 | 2 / 2 |
| Q9UIF8 | Bromodomain adjacent to zinc finger domain protein 2B | Unclassified protein | C00000615 C00002770 | 0 / 0 |
| O94782 | Ubiquitin carboxyl-terminal hydrolase 1 | Enzyme | C00002770 C00003558 | 0 / 0 |
| P43220 | Glucagon-like peptide 1 receptor | Glucagon-like peptide receptor | C00003741 C00003841 | 0 / 0 |
| P03956 | Interstitial collagenase | M10A | C00000615 C00002770 | 0 / 1 |
| Q04206 | Transcription factor p65 | Transcription Factor | C00003558 C00003741 | 0 / 0 |
| Q9Y253 | DNA polymerase eta | Enzyme | C00002770 C00003741 | 1 / 1 |
| P08183 | Multidrug resistance protein 1 | drug | C00003672 C00013596 | 1 / 0 |
| Q9HC16 | DNA dC->dU-editing enzyme APOBEC-3G | Enzyme | C00003741 | 0 / 0 |
| P40763 | Signal transducer and activator of transcription 3 | Transcription Factor | C00002770 | 1 / 2 |
| P00734 | Prothrombin | S1A | C00003672 | 4 / 2 |
| P00915 | Carbonic anhydrase 1 | Lyase | C00000615 | 0 / 0 |
| P08151 | Zinc finger protein GLI1 | Unclassified protein | C00003741 | 0 / 0 |
| P39748 | Flap endonuclease 1 | Enzyme | C00002770 | 0 / 0 |
| P12931 | Proto-oncogene tyrosine-protein kinase Src | Src | C00002770 | 0 / 0 |
| P06280 | Alpha-galactosidase A | Enzyme | C00000615 | 1 / 1 |
| Q96GD4 | Aurora kinase B | Aur | C00003894 | 0 / 0 |
| P35968 | Vascular endothelial growth factor receptor 2 | Vegfr | C00003894 | 1 / 0 |
| Q8TDS4 | Hydroxycarboxylic acid receptor 2 | Hydroxycarboxylic acid receptor | C00000615 | 0 / 0 |
| O15379 | Histone deacetylase 3 | Hydrolase | C00003558 | 0 / 0 |
| Q13133 | Oxysterols receptor LXR-alpha | NR1H3 | C00003741 | 0 / 0 |
| P42330 | Aldo-keto reductase family 1 member C3 | Enzyme | C00000615 | 0 / 0 |
| Q9UQL6 | Histone deacetylase 5 | Hydrolase | C00003558 | 0 / 0 |
| P28482 | Mitogen-activated protein kinase 1 | Erk | C00000615 | 0 / 0 |
| O43570 | Carbonic anhydrase 12 | Lyase | C00000615 | 1 / 2 |
| Q16790 | Carbonic anhydrase 9 | Lyase | C00000615 | 0 / 1 |
| P08253 | 72 kDa type IV collagenase | M10A | C00000615 | 1 / 3 |
| P55055 | Oxysterols receptor LXR-beta | NR1H3 | C00003741 | 0 / 0 |
| P28845 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | Enzyme | C00003558 | 1 / 1 |
| Q9UNQ0 | ATP-binding cassette sub-family G member 2 | ATP binding cassette | C00013596 | 2 / 0 |
| P51692 | Signal transducer and activator of transcription 5B | Unclassified protein | C00002770 | 1 / 1 |
| Q04828 | Aldo-keto reductase family 1 member C1 | Enzyme | C00000615 | 0 / 0 |
| Q9ULX7 | Carbonic anhydrase 14 | Lyase | C00000615 | 0 / 0 |
| Q01453 | Peripheral myelin protein 22 | Unclassified protein | C00000615 | 5 / 2 |
| P23280 | Carbonic anhydrase 6 | Lyase | C00000615 | 0 / 0 |
| P11388 | DNA topoisomerase 2-alpha | Isomerase | C00003741 | 0 / 0 |
| P56524 | Histone deacetylase 4 | Hydrolase | C00003558 | 1 / 1 |
| P11387 | DNA topoisomerase 1 | Isomerase | C00003741 | 0 / 0 |
| P30305 | M-phase inducer phosphatase 2 | Ser_Thr_Tyr | C00003558 | 0 / 0 |
| P05771 | Protein kinase C beta type | Alpha | C00003741 | 0 / 0 |
| P35228 | Nitric oxide synthase, inducible | Enzyme | C00019064 | 1 / 1 |
| P00533 | Epidermal growth factor receptor | TK tyrosine-protein kinase EGFR subfamily | C00000615 | 1 / 8 |
| Q9NR56 | Muscleblind-like protein 1 | Unclassified protein | C00002770 | 1 / 0 |
| P54132 | Bloom syndrome protein | Enzyme | C00002770 | 1 / 2 |
| P52895 | Aldo-keto reductase family 1 member C2 | Enzyme | C00000615 | 1 / 0 |
| Q9GZT9 | Egl nine homolog 1 | Enzyme | C00000615 | 1 / 1 |
| P15559 | NAD(P)H dehydrogenase [quinone] 1 | Enzyme | C00003741 | 0 / 0 |
| P06241 | Tyrosine-protein kinase Fyn | Src | C00002770 | 0 / 0 |
| Q16236 | Nuclear factor erythroid 2-related factor 2 | Unclassified protein | C00003841 | 0 / 0 |
| Q07869 | Peroxisome proliferator-activated receptor alpha | NR1C1 | C00003558 | 0 / 0 |
| P07451 | Carbonic anhydrase 3 | Lyase | C00000615 | 0 / 0 |
| P06239 | Tyrosine-protein kinase Lck | Src | C00002770 | 0 / 1 |
| Q02156 | Protein kinase C epsilon type | Eta | C00003741 | 0 / 0 |
| Q9UBN7 | Histone deacetylase 6 | Hydrolase | C00003558 | 0 / 0 |
| P00918 | Carbonic anhydrase 2 | Lyase | C00000615 | 1 / 2 |
| P04054 | Phospholipase A2 | Enzyme | C00019064 | 0 / 0 |
| P22748 | Carbonic anhydrase 4 | Lyase | C00000615 | 1 / 1 |
| P47989 | Xanthine dehydrogenase/oxidase | Oxidoreductase | C00000615 | 1 / 1 |
| O14965 | Aurora kinase A | Aur | C00003894 | 0 / 0 |
| Q13547 | Histone deacetylase 1 | Hydrolase | C00003558 | 0 / 0 |
| P14780 | Matrix metalloproteinase-9 | M10A | C00000615 | 2 / 2 |
| P24298 | Alanine aminotransferase 1 | Enzyme | C00000615 | 0 / 0 |
| P43166 | Carbonic anhydrase 7 | Lyase | C00000615 | 0 / 0 |
| P35218 | Carbonic anhydrase 5A, mitochondrial | Lyase | C00000615 | 0 / 0 |
| P42224 | Signal transducer and activator of transcription 1-alpha/beta | Unclassified protein | C00002770 | 3 / 3 |
| Q9Y2D0 | Carbonic anhydrase 5B, mitochondrial | Lyase | C00000615 | 0 / 0 |
| P04062 | Glucosylceramidase | Enzyme | C00002770 | 6 / 4 |
| P33765 | Adenosine receptor A3 | Adenosine receptor | C00003841 | 0 / 0 |
| Q8IUX4 | DNA dC->dU-editing enzyme APOBEC-3F | Enzyme | C00003741 | 0 / 0 |
| Q12809 | Potassium voltage-gated channel subfamily H member 2 | KCNH, Kv10-12.x (Ether-a-go-go) | C00000615 | 2 / 2 |
| P09917 | Arachidonate 5-lipoxygenase | Oxidoreductase | C00000615 | 0 / 0 |
| P14618 | Pyruvate kinase PKM | Enzyme | C00002770 | 0 / 0 |
| P17516 | Aldo-keto reductase family 1 member C4 | Enzyme | C00000615 | 1 / 0 |
| P07900 | Heat shock protein HSP 90-alpha | Other cytosolic protein | C00000615 | 0 / 0 |
| P08238 | Heat shock protein HSP 90-beta | Other cytosolic protein | C00000615 | 0 / 0 |
| Q9UBT2 | SUMO-activating enzyme subunit 2 | Enzyme | C00003741 | 0 / 0 |
| Q9UBE0 | SUMO-activating enzyme subunit 1 | Unclassified protein | C00003741 | 0 / 0 |
| Q07820 | Induced myeloid leukemia cell differentiation protein Mcl-1 | Other cytosolic protein | C00002770 | 0 / 0 |
| Q9H0H5 | Rac GTPase-activating protein 1 | Unclassified protein | C00002770 | 0 / 0 |
| Q13148 | TAR DNA-binding protein 43 | Unclassified protein | C00003841 | 1 / 1 |
38 Gene in CTD interactions
| gene | gene name | gene description | KNApSAcK metabolite in interactions |
|---|---|---|---|
| 836 | CASP3, CPP32, CPP32B, SCA-1 | caspase 3, apoptosis-related cysteine peptidase (EC:3.4.22.56) |
C00003558
C00003741
C00019064
|
| 7153 | TOP2A, TOP2, TP2A | topoisomerase (DNA) II alpha 170kDa (EC:5.99.1.3) |
C00003558
C00003741
C00019064
|
| 7150 | TOP1, TOPI | topoisomerase (DNA) I (EC:5.99.1.2) |
C00003558
C00003741
C00019064
|
| 5594 | MAPK1, ERK, ERK2, ERT1, MAPK2, P42MAPK, PRKM1, PRKM2, p38, p40, p41, p41mapk | mitogen-activated protein kinase 1 (EC:2.7.11.24) |
C00003741
C00019064
|
| 1544 | CYP1A2, CP12, P3-450, P450(PA) | cytochrome P450, family 1, subfamily A, polypeptide 2 (EC:1.14.14.1) |
C00013596
C00019064
|
| 1543 | CYP1A1, AHH, AHRR, CP11, CYP1, P1-450, P450-C, P450DX | cytochrome P450, family 1, subfamily A, polypeptide 1 (EC:1.14.14.1) |
C00003894
C00013596
|
| 581 | BAX, BCL2L4 | BCL2-associated X protein |
C00003558
C00003741
|
| 5595 | MAPK3, ERK-1, ERK1, ERT2, HS44KDAP, HUMKER1A, P44ERK1, P44MAPK, PRKM3, p44-ERK1, p44-MAPK | mitogen-activated protein kinase 3 (EC:2.7.11.24) |
C00003741
C00019064
|
| 1545 | CYP1B1, CP1B, CYPIB1, GLC3A, P4501B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 (EC:1.14.14.1) |
C00003894
C00013596
|
| 1576 | CYP3A4, CP33, CP34, CYP3A, CYP3A3, CYPIIIA3, CYPIIIA4, HLP, NF-25, P450C3, P450PCN1 | cytochrome P450, family 3, subfamily A, polypeptide 4 (EC:1.14.13.67 1.14.13.97 1.14.13.32 1.14.13.157) |
C00003894
C00019064
|
| 3383 | ICAM1, BB2, CD54, P3.58 | intercellular adhesion molecule 1 |
C00003558
C00019064
|
| 1557 | CYP2C19, CPCJ, CYP2C, P450C2C, P450IIC19 | cytochrome P450, family 2, subfamily C, polypeptide 19 (EC:1.14.13.48 1.14.13.49 1.14.13.80) |
C00003558
C00003894
|
| 841 | CASP8, ALPS2B, CAP4, Casp-8, FLICE, MACH, MCH5 | caspase 8, apoptosis-related cysteine peptidase (EC:3.4.22.61) |
C00003558
C00019064
|
| 142 | PARP1, ADPRT, ADPRT_1, ADPRT1, ARTD1, PARP, PARP-1, PPOL, pADPRT-1 | poly (ADP-ribose) polymerase 1 (EC:2.4.2.30) |
C00003558
|
| 54205 | CYCS, CYC, HCS, THC4 | cytochrome c, somatic |
C00003558
|
| 578 | BAK1, BAK, BAK-LIKE, BCL2L7, CDN1 | BCL2-antagonist/killer 1 |
C00003558
|
| 9131 | AIFM1, AIF, CMTX4, COWCK, COXPD6, PDCD8 | apoptosis-inducing factor, mitochondrion-associated, 1 |
C00003558
|
| 4313 | MMP2, CLG4, CLG4A, MMP-II, MONA, TBE-1 | matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase) (EC:3.4.24.24) |
C00003558
|
| 4318 | MMP9, CLG4B, GELB, MANDP2, MMP-9 | matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase) (EC:3.4.24.35) |
C00003558
|
| 596 | BCL2, Bcl-2, PPP1R50 | B-cell CLL/lymphoma 2 |
C00003558
|
| 7040 | TGFB1, CED, DPD1, LAP, TGFB, TGFbeta | transforming growth factor, beta 1 |
C00003558
|
| 1956 | EGFR, ERBB, ERBB1, HER1, PIG61, mENA | epidermal growth factor receptor (EC:2.7.10.1) |
C00003741
|
| 840 | CASP7, CASP-7, CMH-1, ICE-LAP3, LICE2, MCH3 | caspase 7, apoptosis-related cysteine peptidase (EC:3.4.22.60) |
C00003741
|
| 332 | BIRC5, API4, EPR-1 | baculoviral IAP repeat containing 5 |
C00003741
|
| 1565 | CYP2D6, CPD6, CYP2D, CYP2D7AP, CYP2D7BP, CYP2D7P2, CYP2D8P2, CYP2DL1, CYPIID6, P450-DB1, P450C2D, P450DB1 | cytochrome P450, family 2, subfamily D, polypeptide 6 (EC:1.14.14.1) |
C00003894
|
| 207 | AKT1, AKT, CWS6, PKB, PKB-ALPHA, PRKBA, RAC, RAC-ALPHA | v-akt murine thymoma viral oncogene homolog 1 (EC:2.7.11.1) |
C00003741
|
| 177 | AGER, RAGE | advanced glycosylation end product-specific receptor |
C00019064
|
| 847 | CAT | catalase (EC:1.11.1.6) |
C00019064
|
| 595 | CCND1, BCL1, D11S287E, PRAD1, U21B31 | cyclin D1 |
C00019064
|
| 3065 | HDAC1, GON-10, HD1, RPD3, RPD3L1 | histone deacetylase 1 (EC:3.5.1.98) |
C00019064
|
| 3146 | HMGB1, HMG1, HMG3, SBP-1 | high mobility group box 1 |
C00019064
|
| 4233 | MET, AUTS9, HGFR, RCCP2, c-Met | met proto-oncogene (EC:2.7.10.1) |
C00019064
|
| 4780 | NFE2L2, NRF2 | nuclear factor, erythroid 2-like 2 |
C00019064
|
| 5052 | PRDX1, MSP23, NKEF-A, NKEFA, PAG, PAGA, PAGB, PRX1, PRXI, TDPX2 | peroxiredoxin 1 (EC:1.11.1.15) |
C00019064
|
| 5728 | PTEN, 10q23del, BZS, CWS1, DEC, GLM2, MHAM, MMAC1, PTEN1, TEP1 | phosphatase and tensin homolog (EC:3.1.3.67 3.1.3.16 3.1.3.48) |
C00019064
|
| 6401 | SELE, CD62E, ELAM, ELAM1, ESEL, LECAM2 | selectin E |
C00019064
|
| 7124 | TNF, DIF, TNF-alpha, TNFA, TNFSF2 | tumor necrosis factor |
C00019064
|
| 7412 | VCAM1, CD106, INCAM-100 | vascular cell adhesion molecule 1 |
C00019064
|
Related Diseases
Diseases related to proteins in ChEMBL interactions
OMIM (101)
| OMIM | preferred title | UniProt |
|---|---|---|
| #300438 | 17-beta-hydroxysteroid dehydrogenase x deficiency |
Q99714
|
| #614279 | 46,xy sex reversal 8; srxy8 |
P17516
P52895 |
| #103470 | Albinism, ocular, with sensorineural deafness |
P14679
|
| #203100 | Albinism, oculocutaneous, type ia; oca1a |
P14679
|
| #606952 | Albinism, oculocutaneous, type ib; oca1b |
P14679
|
| #612069 | Amyotrophic lateral sclerosis 10, with or without frontotemporal dementia; als10 |
Q13148
|
| #218030 | Apparent mineralocorticoid excess; ame |
P80365
|
| #613546 | Aromatase deficiency |
P11511
|
| #139300 | Aromatase excess syndrome; aexs |
P11511
|
| #600807 | Asthma, susceptibility to |
Q13093
|
| #209950 | Atypical mycobacteriosis, familial |
P42224
|
| #614490 | Blood group, junior system; jr |
Q9UNQ0
|
| #210900 | Bloom syndrome; blm |
P54132
|
| #600430 | Brachydactyly-mental retardation syndrome; bdmr |
P56524
|
| #614162 | Candidiasis, familial, 7; candf7 |
P42224
|
| #115200 | Cardiomyopathy, dilated, 1a; cmd1a |
P02545
|
| #212112 | Cardiomyopathy, dilated, with hypergonadotropic hypogonadism |
P02545
|
| #118300 | Charcot-marie-tooth disease and deafness |
Q01453
|
| #605588 | Charcot-marie-tooth disease, axonal, type 2b1; cmt2b1 |
P02545
|
| #118220 | Charcot-marie-tooth disease, demyelinating, type 1a; cmt1a |
Q01453
|
| #604931 | Cortisone reductase deficiency 1; cortrd1 |
P28845
|
| #119900 | Digital clubbing, isolated congenital |
P15428
|
| #609535 | Drug metabolism, poor, cyp2c19-related |
P33261
|
| #608902 | Drug metabolism, poor, cyp2d6-related |
P10635
|
| #181350 | Emery-dreifuss muscular dystrophy 2, autosomal dominant; edmd2 |
P02545
|
| #609820 | Erythrocytosis, familial, 3; ecyt3 |
Q9GZT9
|
| #615363 | Estrogen resistance; estrr |
P03372
|
| #301500 | Fabry disease |
P06280
|
| #600274 | Frontotemporal dementia; ftd |
P10636
|
| #608013 | Gaucher disease, perinatal lethal |
P04062
|
| #230800 | Gaucher disease, type i |
P04062
|
| #230900 | Gaucher disease, type ii |
P04062
|
| #231000 | Gaucher disease, type iii |
P04062
|
| #231005 | Gaucher disease, type iiic |
P04062
|
| #137750 | Glaucoma 1, open angle, a; glc1a |
Q16678
|
| #231300 | Glaucoma 3, primary congenital, a; glc3a |
Q16678
|
| #137760 | Glaucoma, primary open angle; poag |
Q16678
|
| #137800 | Glioma susceptibility 1; glm1 |
O75874
|
| #232300 | Glycogen storage disease ii |
P10253
|
| #245590 | Growth hormone insensitivity with immunodeficiency |
P51692
|
| #139393 | Guillain-barre syndrome, familial; gbs |
Q01453
|
| #605130 | Hairy elbows, short stature, facial dysmorphism, and developmental delay |
Q03164
|
| #610140 | Heart-hand syndrome, slovenian type |
P02545
|
| #602089 | Hemangioma, capillary infantile |
P35968
|
| #176670 | Hutchinson-gilford progeria syndrome; hgps |
P02545
|
| #147060 | Hyper-ige recurrent infection syndrome, autosomal dominant |
P40763
|
| #143860 | Hyperchlorhidrosis, isolated |
O43570
|
| #145000 | Hyperparathyroidism 1; hrpt1 |
O00255
|
| #603373 | Hyperthyroidism, familial gestational |
P16473
|
| #609152 | Hyperthyroidism, nonautoimmune |
P16473
|
| #145900 | Hypertrophic neuropathy of dejerine-sottas |
Q01453
|
| #259100 | Hypertrophic osteoarthropathy, primary, autosomal recessive, 1; phoar1 |
P15428
|
| #275200 | Hypothyroidism, congenital, nongoitrous, 1; chng1 |
P16473
|
| #147050 | Ige responsiveness, atopic; iger |
Q13093
|
| #612244 | Inflammatory bowel disease 13; ibd13 |
P08183
|
| #603932 | Intervertebral disc disease; idd |
P14780
|
| #607785 | Juvenile myelomonocytic leukemia; jmml |
Q06124
|
| #151100 | Leopard syndrome 1 |
Q06124
|
| #151660 | Lipodystrophy, familial partial, type 2; fpld2 |
P02545
|
| #613688 | Long qt syndrome 2; lqt2 |
Q12809
|
| #211980 | Lung cancer |
P00533
|
| #611162 | Malaria, susceptibility to |
P35228
|
| #248370 | Mandibuloacral dysplasia with type a lipodystrophy; mada |
P02545
|
| #300705 | Mental retardation, x-linked 17; mrx17 |
Q99714
|
| #300220 | Mental retardation, x-linked, syndromic 10; mrxs10 |
Q99714
|
| #156250 | Metachondromatosis; metcds |
Q06124
|
| #613073 | Metaphyseal anadysplasia 2; mandp2 |
P14780
|
| #601492 | Mucopolysaccharidosis, type ix; mps9 |
Q12794
|
| #259600 | Multicentric osteolysis, nodulosis, and arthropathy; mona |
P08253
|
| #131100 | Multiple endocrine neoplasia, type i; men1 |
O00255
|
| #613205 | Muscular dystrophy, congenital, lmna-related |
P02545
|
| #159001 | Muscular dystrophy, limb-girdle, type 1b; lgmd1b |
P02545
|
| #613796 | Mycobacterial and viral infections, susceptibility to, autosomal recessive |
P42224
|
| #160900 | Myotonic dystrophy 1; dm1 |
Q9NR56
|
| #162500 | Neuropathy, hereditary, with liability to pressure palsies; hnpp |
Q01453
|
| #163950 | Noonan syndrome 1; ns1 |
Q06124
|
| #259730 | Osteopetrosis, autosomal recessive 3; optb3 |
P00918
|
| #168600 | Parkinson disease, late-onset; pd |
P04062
|
| #260540 | Parkinson-dementia syndrome |
P10636
|
| #604229 | Peters anomaly |
Q16678
|
| #172700 | Pick disease of brain |
P10636
|
| #601399 | Platelet disorder, familial, with associated myeloid malignancy |
Q01196
|
| #614278 | Platelet-activating factor acetylhydrolase deficiency; pafad |
Q13093
|
| #614390 | Pregnancy loss, recurrent, susceptibility to, 2; rprgl2 |
P00734
|
| #613679 | Prothrombin deficiency, congenital |
P00734
|
| #275210 | Restrictive dermopathy, lethal |
P02545
|
| #600852 | Retinitis pigmentosa 17; rp17 |
P22748
|
| #604906 | Schizophrenia 9; sczd9 |
P49798
|
| #181500 | Schizophrenia; sczd |
P49798
|
| #609620 | Short qt syndrome 1; sqt1 |
Q12809
|
| #601800 | Skin/hair/eye pigmentation, variation in, 3; shep3 |
P14679
|
| #607250 | Spinocerebellar ataxia, autosomal recessive, with axonal neuropathy; scan1 |
Q9NUW8
|
| #601367 | Stroke, ischemic |
P00734
|
| #601104 | Supranuclear palsy, progressive, 1; psnp1 |
P10636
|
| #188050 | Thrombophilia due to thrombin defect; thph1 |
P00734
|
| #188570 | Thyroid hormone resistance, generalized, autosomal dominant; grth |
P10828
|
| #274300 | Thyroid hormone resistance, generalized, autosomal recessive; grth |
P10828
|
| #145650 | Thyroid hormone resistance, selective pituitary; prth |
P10828
|
| #138900 | Uric acid concentration, serum, quantitative trait locus 1; uaqtl1 |
Q9UNQ0
|
| #278300 | Xanthinuria, type i |
P47989
|
| #278750 | Xeroderma pigmentosum, variant type; xpv |
Q9Y253
|
KEGG DISEASE (91)
| KEGG | name | UniProt |
|---|---|---|
| H00033 | Adrenal carcinoma |
O00255
(related)
|
| H00034 | Carcinoid |
O00255
(related)
|
| H00045 | Malignant islet cell carcinoma |
O00255
(related)
|
| H00246 | Primary hyperparathyroidism |
O00255
(related)
|
| H01102 | Pituitary adenomas |
O00255
(related)
|
| H01302 | Hyperchlorhidrosis isolated (HCHLH) |
O43570
(related)
|
| H00021 | Renal cell carcinoma |
O43570
(marker)
Q16790 (marker) |
| H00016 | Oral cancer |
P00533
(related)
P00533 (marker) P40763 (related) |
| H00017 | Esophageal cancer |
P00533
(related)
P35228 (related) P35354 (related) |
| H00018 | Gastric cancer |
P00533
(related)
|
| H00022 | Bladder cancer |
P00533
(related)
|
| H00028 | Choriocarcinoma |
P00533
(related)
P03956 (related) P08253 (related) |
| H00030 | Cervical cancer |
P00533
(related)
|
| H00042 | Glioma |
P00533
(related)
P00533 (marker) |
| H00055 | Laryngeal cancer |
P00533
(related)
P00533 (marker) |
| H00223 | Inherited thrombophilia |
P00734
(related)
|
| H01254 | Congenital prothrombin deficiency |
P00734
(related)
|
| H00241 | Combined proximal and distal renal tubular acidosis (RTA type 3) |
P00918
(related)
|
| H00436 | Osteopetrosis |
P00918
(related)
|
| H00264 | Charcot-Marie-Tooth disease (CMT) |
P02545
(related)
Q01453 (related) |
| H00294 | Dilated cardiomyopathy (DCM) |
P02545
(related)
|
| H00420 | Familial partial lipodystrophy (FPL) |
P02545
(related)
|
| H00563 | Emery-Dreifuss muscular dystrophy |
P02545
(related)
|
| H00590 | Congenital muscular dystrophies (CMD/MDC) |
P02545
(related)
|
| H00593 | Limb-girdle muscular dystrophy (LGMD) |
P02545
(related)
|
| H00601 | Hutchinson-Gilford progeria syndrome |
P02545
(related)
|
| H00663 | Restrictive dermopathy |
P02545
(related)
|
| H00665 | Mandibuloacral dysplasia |
P02545
(related)
|
| H01216 | Left ventricular noncompaction (LVNC) |
P02545
(related)
|
| H00026 | Endometrial Cancer |
P03372
(marker)
|
| H00066 | Lewy body dementia (LBD) |
P04062
(related)
|
| H00126 | Gaucher disease |
P04062
(related)
|
| H00426 | Defects in the degradation of ganglioside |
P04062
(related)
|
| H00810 | Progressive myoclonic epilepsy (PME) |
P04062
(related)
|
| H00093 | Combined immunodeficiencies (CIDs) |
P06239
(related)
|
| H00125 | Fabry disease |
P06280
(related)
|
| H00025 | Penile cancer |
P08253
(related)
P14780 (related) P35354 (related) |
| H00472 | Torg-Winchester syndrome |
P08253
(related)
|
| H00036 | Osteosarcoma |
P08684
(marker)
|
| H00069 | Glycogen storage diseases (GSD) |
P10253
(related)
|
| H00058 | Amyotrophic lateral sclerosis (ALS) |
P10636
(related)
Q13148 (related) |
| H00077 | Progressive supranuclear palsy (PSP) |
P10636
(related)
|
| H00078 | Frontotemporal lobar degeneration (FTLD) |
P10636
(related)
|
| H00249 | Thyroid hormone resistance syndrome |
P10828
(related)
|
| H00599 | 46,XX disorders of sex development (Disorders related to androgen excess) |
P11511
(related)
|
| H00794 | Aromatase excess syndrome |
P11511
(related)
|
| H01205 | Coumarin resistance |
P11712
(related)
|
| H00168 | Oculocutaneous albinism (OCA) |
P14679
(related)
|
| H00038 | Malignant melanoma |
P14679
(marker)
|
| H00479 | Metaphyseal dysplasias |
P14780
(related)
|
| H00457 | Primary hypertrophic osteoarthropathy (PHO) |
P15428
(related)
|
| H01246 | Isolated congenital nail clubbing (ICNC) |
P15428
(related)
|
| H00250 | Congenital nongoitrous hypothyroidism (CHNG) |
P16473
(related)
|
| H01269 | Congenital hyperthyroidism |
P16473
(related)
|
| H00408 | Type I diabetes mellitus |
P17706
(related)
|
| H00527 | Retinitis pigmentosa (RP) |
P22748
(related)
|
| H01111 | Cortisone reductase deficiency (CRD) |
P28845
(related)
|
| H01171 | Poor drug metabolism (PM) |
P33261
(related)
|
| H00046 | Cholangiocarcinoma |
P35354
(related)
|
| H00107 | Other well-defined immunodeficiency syndromes |
P40763
(related)
|
| H00089 | IFN-gamma/IL-12 axis |
P42224
(related)
|
| H00363 | Candidiasis |
P42224
(related)
|
| H01109 | Chronic mucocutaneous candidiasis (CMC) |
P42224
(related)
|
| H00192 | Xanthinuria |
P47989
(related)
|
| H00931 | Growth hormone insensitivity with immunodeficiency |
P51692
(related)
|
| H00094 | DNA repair defects |
P54132
(related)
|
| H00296 | Defects in RecQ helicases |
P54132
(related)
|
| H00561 | Brachydacytly-mental retardation syndrome and Smith-Magenis syndrome |
P56524
(related)
|
| H00259 | Apparent mineralocorticoid excess syndrome |
P80365
(related)
|
| H00001 | Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) |
Q01196
(related)
Q01196 (marker) Q03164 (related) Q03164 (marker) |
| H00003 | Acute myeloid leukemia (AML) |
Q01196
(related)
Q01196 (marker) Q13951 (marker) |
| H00004 | Chronic myeloid leukemia (CML) |
Q01196
(related)
|
| H00978 | Thrombocytopenia (THC) |
Q01196
(related)
|
| H01296 | Hereditary neuropathy with liability to pressure palsies (HNPP) |
Q01453
(related)
|
| H00002 | Acute lymphoblastic leukemia (ALL) (precursor T lymphoblastic leukemia) |
Q03164
(related)
|
| H00523 | Noonan syndrome and related disorders |
Q06124
(related)
|
| H01018 | Metachondromatosis |
Q06124
(related)
|
| H00133 | Mucopolysaccharidosis type IX (MPS9) |
Q12794
(related)
|
| H00421 | Mucopolysaccharidosis (MPS) |
Q12794
(related)
|
| H00720 | Long QT syndrome |
Q12809
(related)
|
| H00725 | Short QT syndrome |
Q12809
(related)
|
| H00612 | Primary open angle glaucoma |
Q16678
(related)
|
| H01075 | Peters anomaly |
Q16678
(related)
|
| H01159 | Anterior segment dysgenesis (ASD) |
Q16678
(related)
|
| H01203 | Primary congenital glaucoma (PCG) |
Q16678
(related)
|
| H00480 | Non-syndromic X-linked mental retardation |
Q99714
(related)
|
| H00658 | Syndromic X-linked mental retardation |
Q99714
(related)
|
| H00925 | 2-Methyl-3-hydroxybutyryl-CoA dehydrogenase (MHBD) deficiency |
Q99714
(related)
|
| H00236 | Congenital polycythemia |
Q9GZT9
(related)
|
| H00063 | Spinocerebellar ataxia (SCA) |
Q9NUW8
(related)
|
| H00403 | Disorders of nucleotide excision repair |
Q9Y253
(related)
|
Diseases related to CTD interactions
23 disease in interactions with metabolites
| MESH or OMIM | name |
KNApSAcK
metabolite |
|---|---|---|
| D008103 | Liver Cirrhosis |
C00003741
C00003558 C00019064 |
| D006949 | Hyperlipidemias |
C00003558
C00019064 |
| D017202 | Myocardial Ischemia |
C00003558
C00019064 |
| D007249 | Inflammation |
C00003558
C00019064 |
| D009369 | Neoplasms |
C00003558
C00019064 |
| D003921 | Diabetes Mellitus, Experimental |
C00003558
|
| D006943 | Hyperglycemia |
C00003558
|
| D002471 | Cell Transformation, Neoplastic |
C00003558
|
| D006965 | Hyperplasia |
C00003558
|
| D006528 | Carcinoma, Hepatocellular |
C00003558
|
| D001284 | Atrophy |
C00003558
|
| D008545 | Melanoma |
C00003741
|
| D012878 | Skin Neoplasms |
C00003558
|
| D002252 | Carbon Tetrachloride Poisoning |
C00019064
|
| D056486 | Drug-Induced Liver Injury |
C00019064
|
| D050171 | Dyslipidemias |
C00019064
|
| D018149 | Glucose Intolerance |
C00019064
|
| D007674 | Kidney Diseases |
C00019064
|
| D008106 | Liver Cirrhosis, Experimental |
C00019064
|
| D008107 | Liver Diseases |
C00019064
|
| D009765 | Obesity |
C00019064
|
| D011041 | Poisoning |
C00019064
|
| D011230 | Precancerous Conditions |
C00019064
|