Cinnamomum camphora
Species
KNApSAcK Entry
| Organism name | Cinnamomum camphora |
|---|---|
| Genus | Cinnamomum |
| Family | Lauraceae |
| Kingdom | Plantae |
NCBI taxonomy
Entry
| Linked NCBI taxonomy name | Cinnamomum camphora |
|---|---|
| Linked NCBI taxonomy ID | 13429 |
| Linked level | species |
Family
| Family in NCBI taxonomy | Lauraceae |
|---|---|
| ID | 3433 |
Kingdom (Superkingdom)
| Kingdom (Superkingdom) in NCBI taxonomy | Viridiplantae |
|---|---|
| ID | 33090 |
Plant class
| Plant class | Magnoliophyta |
|---|---|
| ID | 3398 |
Natural Activity
List (39)
| Species | Activity |
|---|---|
| Cinnamomum camphora (L.) J. Presl | Abortifacient |
| Cinnamomum camphora (L.) J. Presl | Analeptic |
| Cinnamomum camphora (L.) J. Presl | Analgesic |
| Cinnamomum camphora (L.) J. Presl | Anthelminthic |
| Cinnamomum camphora (L.) J. Presl | Antiaphrodisiac |
| Cinnamomum camphora (L.) J. Presl | Antibacterial |
| Cinnamomum camphora (L.) J. Presl | Antiitch |
| Cinnamomum camphora (L.) J. Presl | Antirheumatic |
| Cinnamomum camphora (L.) J. Presl | Antiseptic |
| Cinnamomum camphora (L.) J. Presl | Antispasmodic |
| Cinnamomum camphora (L.) J. Presl | Antitussive |
| Cinnamomum camphora (L.) J. Presl | Aphrodisiac |
| Cinnamomum camphora (L.) J. Presl | Bronchosecretolytic |
| Cinnamomum camphora (L.) J. Presl | Bronchospasmolytic |
| Cinnamomum camphora (L.) J. Presl | Calmative |
| Cinnamomum camphora (L.) J. Presl | Candidicide |
| Cinnamomum camphora (L.) J. Presl | Cardiotonic |
| Cinnamomum camphora (L.) J. Presl | Carminative |
| Cinnamomum camphora (L.) J. Presl | Circulotonic |
| Cinnamomum camphora (L.) J. Presl | CNS-Depressant |
| Cinnamomum camphora (L.) J. Presl | CNS-Stimulant |
| Cinnamomum camphora (L.) J. Presl | Convulsant |
| Cinnamomum camphora (L.) J. Presl | Counterritant |
| Cinnamomum camphora (L.) J. Presl | Decongestant |
| Cinnamomum camphora (L.) J. Presl | Diaphoretic |
| Cinnamomum camphora (L.) J. Presl | Emetic |
| Cinnamomum camphora (L.) J. Presl | Expectorant |
| Cinnamomum camphora (L.) J. Presl | Fungicide |
| Cinnamomum camphora (L.) J. Presl | Hyperemic |
| Cinnamomum camphora (L.) J. Presl | Liniment |
| Cinnamomum camphora (L.) J. Presl | Parasiticide |
| Cinnamomum camphora (L.) J. Presl | Respirastimulant |
| Cinnamomum camphora (L.) J. Presl | Rubefacient |
| Cinnamomum camphora (L.) J. Presl | Secretagogue |
| Cinnamomum camphora (L.) J. Presl | Secretolytic |
| Cinnamomum camphora (L.) J. Presl | Sedative |
| Cinnamomum camphora (L.) J. Presl | Stimulant |
| Cinnamomum camphora (L.) J. Presl | Vibriocide |
| Cinnamomum camphora (L.) J. Presl | Vulnerary |
Metabolite list (11)
| KNApSAcK ID | name | ChEMBL link | CTD link |
# of proteins in
ChEMBL interaction / related OMIM / related KEGG DISEASE |
# of genes in
CTD interaction / related diseases |
KCF-S
cluster |
phytochemical
cluster |
figure |
|---|---|---|---|---|---|---|---|---|
C00007193
|
(+)-Xanthoxylol
|
CHEMBL1688935
CHEMBL1688938 CHEMBL2011539 CHEMBL2011540 CHEMBL2136585 |
7 / 13 / 7 | No. 38 | No. 21 |
|
||
|
C00008815
|
Epicatechin 5,7,3'-trimethyl ether
|
CHEMBL465960
|
No. 73 | No. 15 |
|
|||
|
C00000601
|
(+)-Sesamin
|
CHEMBL43469
CHEMBL252915 CHEMBL1572261 CHEMBL1591714 CHEMBL1708854 CHEMBL1904496 CHEMBL1968861 |
C054125
|
20 / 24 / 15 | 0 / 5 | No. 621 | No. 21 |
|
|
C00002608
|
Hinokinin
/ Hinoquinin / (-)-Hinokinin / (-)-Hinoquinin |
CHEMBL180970
CHEMBL182073 CHEMBL242011 |
C475934
|
2 / 1 / 1 | No. 629 | No. 21 |
|
|
|
C00011023
|
(+)-Borneol
|
CHEMBL296404
CHEMBL486208 CHEMBL1097205 CHEMBL1968981 |
8 / 5 / 1 | No. 649 | No. 35 |
|
||
|
C00010290
|
2,6-Dimethyl-1,7-octadiene-3,6-diol
|
No. 958 | No. 34 |
|
||||
|
C00002714
|
Apiol
/ Apiole / Parsley apiole |
CHEMBL1560118
|
3 / 0 / 1 | No. 1917 | No. 6 |
|
||
|
C00000819
|
(+)-Camphor
|
CHEMBL504760
CHEMBL1316134 |
D002164
|
99 / 56 / 51 | 5 / 3 | No. 1921 | No. 35 |
|
|
C00021844
|
Campherenol
|
No. 1968 |
|
|||||
|
C00021845
|
Campherenone
|
No. 3487 |
|
|||||
|
C00002771
|
Safrole
|
CHEMBL242273
|
D012451
|
91 / 40 / 34 | 13 / 5 | No. 3773 |
|
Human Protein / Gene in interactions
124 ChEMBL Protein in interactions
| accession | description | class description | KNApSAcK metabolite in interactions |
# of diseases
(OMIM / KEGG) |
|---|---|---|---|---|
| P08684 | Cytochrome P450 3A4 | Cytochrome P450 3A4 | C00000601 C00000819 C00002608 C00002714 C00002771 | 0 / 1 |
| P10635 | Cytochrome P450 2D6 | Cytochrome P450 2D6 | C00000601 C00000819 C00002608 C00002771 | 1 / 0 |
| P33261 | Cytochrome P450 2C19 | Cytochrome P450 2C19 | C00000601 C00000819 C00002771 | 1 / 1 |
| P10636 | Microtubule-associated protein tau | Unclassified protein | C00000601 C00000819 C00002771 | 4 / 3 |
| P28482 | Mitogen-activated protein kinase 1 | Erk | C00000601 C00000819 C00002771 | 0 / 0 |
| P11712 | Cytochrome P450 2C9 | Cytochrome P450 2C9 | C00000601 C00000819 C00002771 | 0 / 1 |
| O76074 | cGMP-specific 3',5'-cyclic phosphodiesterase | PDE_5A | C00000819 C00002771 | 0 / 0 |
| P08246 | Neutrophil elastase | S1A | C00000819 C00002771 | 2 / 1 |
| P33765 | Adenosine receptor A3 | Adenosine receptor | C00000819 C00002771 | 0 / 0 |
| Q16539 | Mitogen-activated protein kinase 14 | p38 | C00000819 C00002771 | 0 / 0 |
| P49146 | Neuropeptide Y receptor type 2 | Neuropeptide Y receptor | C00000819 C00002771 | 0 / 0 |
| P29466 | Caspase-1 | C14 | C00000819 C00002771 | 0 / 0 |
| P17252 | Protein kinase C alpha type | Alpha | C00000819 C00002771 | 0 / 0 |
| P27361 | Mitogen-activated protein kinase 3 | Erk | C00000819 C00002771 | 0 / 0 |
| Q13148 | TAR DNA-binding protein 43 | Unclassified protein | C00000601 C00007193 | 1 / 1 |
| P14780 | Matrix metalloproteinase-9 | M10A | C00000819 C00002771 | 2 / 2 |
| P25025 | C-X-C chemokine receptor type 2 | CXC chemokine receptor | C00000819 C00002771 | 0 / 0 |
| P00918 | Carbonic anhydrase 2 | Lyase | C00000819 C00002771 | 1 / 2 |
| P07550 | Beta-2 adrenergic receptor | Adrenergic receptor | C00000819 C00002771 | 0 / 1 |
| P21397 | Amine oxidase [flavin-containing] A | Oxidoreductase | C00000819 C00002771 | 1 / 1 |
| P25021 | Histamine H2 receptor | Histamine receptor | C00000819 C00002771 | 0 / 0 |
| P35367 | Histamine H1 receptor | Histamine receptor | C00000819 C00002771 | 0 / 0 |
| Q01959 | Sodium-dependent dopamine transporter | Dopamine | C00000819 C00002771 | 1 / 0 |
| P08912 | Muscarinic acetylcholine receptor M5 | Acetylcholine receptor | C00000819 C00002771 | 0 / 0 |
| P18825 | Alpha-2C adrenergic receptor | Adrenergic receptor | C00000819 C00002771 | 0 / 0 |
| P13945 | Beta-3 adrenergic receptor | Adrenergic receptor | C00000819 C00002771 | 0 / 0 |
| P25024 | C-X-C chemokine receptor type 1 | CXC chemokine receptor | C00000819 C00002771 | 0 / 0 |
| P06241 | Tyrosine-protein kinase Fyn | Src | C00000819 C00002771 | 0 / 0 |
| Q08209 | Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform | Ser_Thr | C00000819 C00002771 | 0 / 0 |
| P35354 | Prostaglandin G/H synthase 2 | Oxidoreductase | C00000819 C00002771 | 0 / 3 |
| P06239 | Tyrosine-protein kinase Lck | Src | C00000819 C00002771 | 0 / 1 |
| P00533 | Epidermal growth factor receptor | TK tyrosine-protein kinase EGFR subfamily | C00000819 C00002771 | 1 / 8 |
| P24557 | Thromboxane-A synthase | Cytochrome P450 5A1 | C00000819 C00002771 | 1 / 1 |
| P14416 | D(2) dopamine receptor | Dopamine receptor | C00000819 C00002771 | 2 / 0 |
| P23219 | Prostaglandin G/H synthase 1 | Oxidoreductase | C00000819 C00002771 | 0 / 0 |
| P37288 | Vasopressin V1a receptor | Vasopressin and oxytocin receptor | C00000819 C00002771 | 0 / 0 |
| P41145 | Kappa-type opioid receptor | Opioid receptor | C00000819 C00002771 | 0 / 0 |
| Q9Y271 | Cysteinyl leukotriene receptor 1 | Leukotriene receptor | C00000819 C00002771 | 0 / 0 |
| P29274 | Adenosine receptor A2a | Adenosine receptor | C00000819 C00002771 | 0 / 0 |
| P25929 | Neuropeptide Y receptor type 1 | Neuropeptide Y receptor | C00000819 C00002771 | 0 / 0 |
| P50052 | Type-2 angiotensin II receptor | Angiotensin receptor | C00000819 C00002771 | 1 / 1 |
| P18089 | Alpha-2B adrenergic receptor | Adrenergic receptor | C00000819 C00002771 | 0 / 0 |
| P17948 | Vascular endothelial growth factor receptor 1 | Vegfr | C00000819 C00002771 | 0 / 0 |
| P41968 | Melanocortin receptor 3 | Melanocortin receptor | C00000819 C00002771 | 1 / 0 |
| P30542 | Adenosine receptor A1 | Adenosine receptor | C00000819 C00002771 | 0 / 0 |
| P11509 | Cytochrome P450 2A6 | Cytochrome P450 2A6 | C00000819 C00002771 | 0 / 0 |
| P25100 | Alpha-1D adrenergic receptor | Adrenergic receptor | C00000819 C00002771 | 0 / 0 |
| O75496 | Geminin | Unclassified protein | C00000601 C00007193 | 0 / 0 |
| P23975 | Sodium-dependent noradrenaline transporter | Norepinephrine | C00000819 C00002771 | 1 / 1 |
| Q16236 | Nuclear factor erythroid 2-related factor 2 | Unclassified protein | C00000601 C00002771 | 0 / 0 |
| P04035 | 3-hydroxy-3-methylglutaryl-coenzyme A reductase | Oxidoreductase | C00000819 C00002771 | 0 / 0 |
| P08913 | Alpha-2A adrenergic receptor | Adrenergic receptor | C00000819 C00002771 | 0 / 0 |
| P21917 | D(4) dopamine receptor | Dopamine receptor | C00000819 C00002771 | 0 / 0 |
| P30988 | Calcitonin receptor | Calcitonin receptor | C00000819 C00002771 | 0 / 0 |
| P35462 | D(3) dopamine receptor | Dopamine receptor | C00000819 C00002771 | 1 / 0 |
| P41143 | Delta-type opioid receptor | Opioid receptor | C00000819 C00002771 | 0 / 0 |
| Q92731 | Estrogen receptor beta | NR3A2 | C00000819 C00002771 | 0 / 1 |
| P41595 | 5-hydroxytryptamine receptor 2B | Serotonin receptor | C00000819 C00002771 | 0 / 0 |
| P25101 | Endothelin-1 receptor | Endothelin receptor | C00000819 C00002771 | 0 / 0 |
| P30411 | B2 bradykinin receptor | Bradykinin receptor | C00000819 C00002771 | 0 / 0 |
| P32245 | Melanocortin receptor 4 | Melanocortin receptor | C00000819 C00002771 | 1 / 0 |
| P32238 | Cholecystokinin receptor type A | Cholecystokinin receptor | C00000819 C00002771 | 0 / 0 |
| P08311 | Cathepsin G | S1A | C00000819 C00002771 | 0 / 0 |
| Q99720 | Sigma non-opioid intracellular receptor 1 | Membrane receptor | C00000819 C00002771 | 1 / 0 |
| P43220 | Glucagon-like peptide 1 receptor | Glucagon-like peptide receptor | C00000601 C00007193 | 0 / 0 |
| P03956 | Interstitial collagenase | M10A | C00000819 C00002771 | 0 / 1 |
| P32241 | Vasoactive intestinal polypeptide receptor 1 | Vasoactive intestinal peptide receptor | C00000819 C00002771 | 0 / 0 |
| P63092 | Guanine nucleotide-binding protein G(s) subunit alpha isoforms short | Other membrane protein | C00000601 C00007193 | 7 / 3 |
| P05181 | Cytochrome P450 2E1 | Cytochrome P450 2E1 | C00000819 C00002771 | 0 / 0 |
| O94782 | Ubiquitin carboxyl-terminal hydrolase 1 | Enzyme | C00000601 C00002714 | 0 / 0 |
| P04150 | Glucocorticoid receptor | NR3C1 | C00000819 C00002771 | 0 / 1 |
| P08172 | Muscarinic acetylcholine receptor M2 | Acetylcholine receptor | C00000819 C00002771 | 2 / 0 |
| P11229 | Muscarinic acetylcholine receptor M1 | Acetylcholine receptor | C00000819 C00002771 | 0 / 0 |
| P21554 | Cannabinoid receptor 1 | Cannabinoid receptor | C00000819 C00002771 | 0 / 0 |
| P31645 | Sodium-dependent serotonin transporter | Serotonin | C00000819 C00002771 | 2 / 0 |
| P33032 | Melanocortin receptor 5 | Melanocortin receptor | C00000819 C00002771 | 0 / 0 |
| P04626 | Receptor tyrosine-protein kinase erbB-2 | TK tyrosine-protein kinase EGFR subfamily | C00000819 C00002771 | 5 / 9 |
| P20309 | Muscarinic acetylcholine receptor M3 | Acetylcholine receptor | C00000819 C00002771 | 1 / 0 |
| P21452 | Substance-K receptor | Neurokinin receptor | C00000819 C00002771 | 0 / 0 |
| P51679 | C-C chemokine receptor type 4 | CC chemokine receptor | C00000819 C00002771 | 0 / 0 |
| P51681 | C-C chemokine receptor type 5 | CC chemokine receptor | C00000819 C00002771 | 3 / 0 |
| P50406 | 5-hydroxytryptamine receptor 6 | Serotonin receptor | C00000819 C00002771 | 0 / 0 |
| P25105 | Platelet-activating factor receptor | PAF receptor | C00000819 C00002771 | 0 / 0 |
| P41597 | C-C chemokine receptor type 2 | CC chemokine receptor | C00000819 C00002771 | 1 / 0 |
| P21728 | D(1A) dopamine receptor | Dopamine receptor | C00000819 C00002771 | 0 / 0 |
| P08575 | Receptor-type tyrosine-protein phosphatase C | Enzyme | C00000819 C00002771 | 2 / 1 |
| P05177 | Cytochrome P450 1A2 | Cytochrome P450 1A2 | C00000819 C00002771 | 0 / 0 |
| P25103 | Substance-P receptor | Neurokinin receptor | C00000819 C00002771 | 0 / 0 |
| P08173 | Muscarinic acetylcholine receptor M4 | Acetylcholine receptor | C00000819 C00002771 | 0 / 0 |
| P35372 | Mu-type opioid receptor | Opioid receptor | C00000819 C00002771 | 0 / 0 |
| Q96QE3 | ATPase family AAA domain-containing protein 5 | Unclassified protein | C00000601 C00000819 | 0 / 0 |
| P28335 | 5-hydroxytryptamine receptor 2C | Serotonin receptor | C00000819 C00002771 | 0 / 0 |
| P28223 | 5-hydroxytryptamine receptor 2A | Serotonin receptor | C00000819 C00002771 | 0 / 0 |
| Q12809 | Potassium voltage-gated channel subfamily H member 2 | KCNH, Kv10-12.x (Ether-a-go-go) | C00000819 C00002771 | 2 / 2 |
| P22303 | Acetylcholinesterase | Hydrolase | C00000819 C00002771 | 1 / 0 |
| P08588 | Beta-1 adrenergic receptor | Adrenergic receptor | C00000819 C00002771 | 1 / 0 |
| P03372 | Estrogen receptor | NR3A1 | C00000819 C00002771 | 1 / 1 |
| Q9Y4X1 | UDP-glucuronosyltransferase 2A1 | Enzyme | C00011023 | 0 / 0 |
| Q9HAW9 | UDP-glucuronosyltransferase 1-8 | Enzyme | C00011023 | 0 / 0 |
| P51449 | Nuclear receptor ROR-gamma | Nuclear hormone receptor subfamily 1 group F member 3 | C00000819 | 0 / 0 |
| P15428 | 15-hydroxyprostaglandin dehydrogenase [NAD(+)] | Enzyme | C00000601 | 2 / 2 |
| O75762 | Transient receptor potential cation channel subfamily A member 1 | Unclassified protein | C00000819 | 1 / 0 |
| Q96RI1 | Bile acid receptor | NR1H4 | C00000819 | 0 / 0 |
| P37231 | Peroxisome proliferator-activated receptor gamma | NR1C3 | C00007193 | 5 / 3 |
| P16050 | Arachidonate 15-lipoxygenase | Enzyme | C00002714 | 0 / 0 |
| Q16637 | Survival motor neuron protein | Unclassified protein | C00000601 | 4 / 1 |
| Q8NET8 | Transient receptor potential cation channel subfamily V member 3 | Unclassified protein | C00000819 | 1 / 0 |
| P83916 | Chromobox protein homolog 1 | Unclassified protein | C00000601 | 0 / 0 |
| Q9UNA4 | DNA polymerase iota | Enzyme | C00000601 | 0 / 0 |
| P22309 | UDP-glucuronosyltransferase 1-1 | Enzyme | C00011023 | 5 / 1 |
| P22310 | UDP-glucuronosyltransferase 1-4 | Enzyme | C00011023 | 3 / 0 |
| P19224 | UDP-glucuronosyltransferase 1-6 | Enzyme | C00011023 | 0 / 0 |
| P54855 | UDP-glucuronosyltransferase 2B15 | Enzyme | C00011023 | 0 / 0 |
| O60656 | UDP-glucuronosyltransferase 1-9 | Enzyme | C00011023 | 0 / 0 |
| P84022 | Mothers against decapentaplegic homolog 3 | Unclassified protein | C00000601 | 2 / 0 |
| P00352 | Retinal dehydrogenase 1 | Enzyme | C00000819 | 0 / 0 |
| Q07869 | Peroxisome proliferator-activated receptor alpha | NR1C1 | C00007193 | 0 / 0 |
| O15296 | Arachidonate 15-lipoxygenase B | Enzyme | C00000601 | 0 / 0 |
| P11473 | Vitamin D3 receptor | NR1I1 | C00000601 | 2 / 3 |
| P16662 | UDP-glucuronosyltransferase 2B7 | Enzyme | C00011023 | 0 / 0 |
| P02545 | Prelamin-A/C | Unclassified protein | C00000819 | 11 / 10 |
| O00255 | Menin | Unclassified protein | C00000819 | 2 / 5 |
| Q03164 | Histone-lysine N-methyltransferase 2A | Enzyme | C00000819 | 1 / 2 |
| Q03181 | Peroxisome proliferator-activated receptor delta | NR1C2 | C00007193 | 0 / 0 |
18 Gene in CTD interactions
| gene | gene name | gene description | KNApSAcK metabolite in interactions |
|---|---|---|---|
| 1555 | CYP2B6, CPB6, CYP2B, CYP2B7, CYP2B7P, CYPIIB6, EFVM, IIB1, P450 | cytochrome P450, family 2, subfamily B, polypeptide 6 (EC:1.14.14.1) |
C00000819
|
| 2554 | GABRA1, ECA4, EJM, EJM5 | gamma-aminobutyric acid (GABA) A receptor, alpha 1 |
C00000819
|
| 2561 | GABRB2 | gamma-aminobutyric acid (GABA) A receptor, beta 2 |
C00000819
|
| 2566 | GABRG2, CAE2, ECA2, GEFSP3 | gamma-aminobutyric acid (GABA) A receptor, gamma 2 |
C00000819
|
| 162514 | TRPV3, OLMS, VRL3 | transient receptor potential cation channel, subfamily V, member 3 |
C00000819
|
| 317 | APAF1, APAF-1, CED4 | apoptotic peptidase activating factor 1 |
C00002771
|
| 581 | BAX, BCL2L4 | BCL2-associated X protein |
C00002771
|
| 596 | BCL2, Bcl-2, PPP1R50 | B-cell CLL/lymphoma 2 |
C00002771
|
| 637 | BID, FP497 | BH3 interacting domain death agonist |
C00002771
|
| 836 | CASP3, CPP32, CPP32B, SCA-1 | caspase 3, apoptosis-related cysteine peptidase (EC:3.4.22.56) |
C00002771
|
| 841 | CASP8, ALPS2B, CAP4, Casp-8, FLICE, MACH, MCH5 | caspase 8, apoptosis-related cysteine peptidase (EC:3.4.22.61) |
C00002771
|
| 842 | CASP9, APAF-3, APAF3, ICE-LAP6, MCH6, PPP1R56 | caspase 9, apoptosis-related cysteine peptidase (EC:3.4.22.62) |
C00002771
|
| 54205 | CYCS, CYC, HCS, THC4 | cytochrome c, somatic |
C00002771
|
| 1544 | CYP1A2, CP12, P3-450, P450(PA) | cytochrome P450, family 1, subfamily A, polypeptide 2 (EC:1.14.14.1) |
C00002771
|
| 1548 | CYP2A6, CPA6, CYP2A, CYP2A3, CYPIIA6, P450C2A, P450PB | cytochrome P450, family 2, subfamily A, polypeptide 6 (EC:1.14.14.1) |
C00002771
|
| 1565 | CYP2D6, CPD6, CYP2D, CYP2D7AP, CYP2D7BP, CYP2D7P2, CYP2D8P2, CYP2DL1, CYPIID6, P450-DB1, P450C2D, P450DB1 | cytochrome P450, family 2, subfamily D, polypeptide 6 (EC:1.14.14.1) |
C00002771
|
| 1571 | CYP2E1, CPE1, CYP2E, P450-J, P450C2E | cytochrome P450, family 2, subfamily E, polypeptide 1 (EC:1.14.13.n7) |
C00002771
|
| 1576 | CYP3A4, CP33, CP34, CYP3A, CYP3A3, CYPIIIA3, CYPIIIA4, HLP, NF-25, P450C3, P450PCN1 | cytochrome P450, family 3, subfamily A, polypeptide 4 (EC:1.14.13.67 1.14.13.97 1.14.13.32 1.14.13.157) |
C00002771
|
Related Diseases
Diseases related to proteins in ChEMBL interactions
OMIM (82)
| OMIM | preferred title | UniProt |
|---|---|---|
| #100100 | Abdominal muscles, absence of, with urinary tract abnormality and cryptorchidism |
P20309
|
| #219080 | Acth-independent macronodular adrenal hyperplasia; aimah |
P63092
|
| #103780 | Alcohol dependence |
P08172
P14416 P31645 |
| #612069 | Amyotrophic lateral sclerosis 10, with or without frontotemporal dementia; als10 |
Q13148
|
| #614373 | Amyotrophic lateral sclerosis 16, juvenile; als16 |
Q99720
|
| #601816 | Bilirubin, serum level of, quantitative trait locus 1; biliqtl1 |
P22309
|
| #602025 | Body mass index quantitative trait locus 9; bmiq9 |
P41968
|
| %606641 | Body mass index; bmi |
P37231
|
| #300615 | Brunner syndrome |
P21397
|
| #115200 | Cardiomyopathy, dilated, 1a; cmd1a |
P02545
|
| #212112 | Cardiomyopathy, dilated, with hypergonadotropic hypogonadism |
P02545
|
| #609338 | Carotid intimal medial thickness 1 |
P37231
|
| #605588 | Charcot-marie-tooth disease, axonal, type 2b1; cmt2b1 |
P02545
|
| #114500 | Colorectal cancer; crc |
P84022
|
| #218800 | Crigler-najjar syndrome, type i |
P22309
P22310 |
| #606785 | Crigler-najjar syndrome, type ii |
P22309
P22310 |
| #162800 | Cyclic neutropenia |
P08246
|
| #612522 | Diabetes mellitus, insulin-dependent, 22; iddm22 |
P51681
|
| #119900 | Digital clubbing, isolated congenital |
P15428
|
| #609535 | Drug metabolism, poor, cyp2c19-related |
P33261
|
| #608902 | Drug metabolism, poor, cyp2d6-related |
P10635
|
| #181350 | Emery-dreifuss muscular dystrophy 2, autosomal dominant; edmd2 |
P02545
|
| #615040 | Episodic pain syndrome, familial, 1; feps1 |
O75762
|
| #615363 | Estrogen resistance; estrr |
P03372
|
| #600274 | Frontotemporal dementia; ftd |
P10636
|
| #613659 | Gastric cancer |
P04626
|
| #137215 | Gastric cancer, hereditary diffuse; hdgc |
P04626
|
| #231095 | Ghosal hematodiaphyseal dysplasia; ghdd |
P24557
|
| #143500 | Gilbert syndrome |
P22309
P22310 |
| #137800 | Glioma susceptibility 1; glm1 |
P04626
P37231 |
| #605130 | Hairy elbows, short stature, facial dysmorphism, and developmental delay |
Q03164
|
| #610140 | Heart-hand syndrome, slovenian type |
P02545
|
| #609423 | Human immunodeficiency virus type 1, susceptibility to |
P41597
P51681 |
| #176670 | Hutchinson-gilford progeria syndrome; hgps |
P02545
|
| #237900 | Hyperbilirubinemia, transient familial neonatal; hblrtfn |
P22309
|
| #145000 | Hyperparathyroidism 1; hrpt1 |
O00255
|
| #259100 | Hypertrophic osteoarthropathy, primary, autosomal recessive, 1; phoar1 |
P15428
|
| #603932 | Intervertebral disc disease; idd |
P14780
|
| #151660 | Lipodystrophy, familial partial, type 2; fpld2 |
P02545
|
| #604367 | Lipodystrophy, familial partial, type 3; fpld3 |
P37231
|
| #613795 | Loeys-dietz syndrome, type 3; lds3 |
P84022
|
| #613688 | Long qt syndrome 2; lqt2 |
Q12809
|
| #211980 | Lung cancer |
P00533
P04626 |
| #608516 | Major depressive disorder; mdd |
P08172
|
| #248370 | Mandibuloacral dysplasia with type a lipodystrophy; mada |
P02545
|
| #174800 | Mccune-albright syndrome; mas |
P63092
|
| %300852 | Mental retardation, x-linked 88; mrx88 |
P50052
|
| #613073 | Metaphyseal anadysplasia 2; mandp2 |
P14780
|
| #131100 | Multiple endocrine neoplasia, type i; men1 |
O00255
|
| #126200 | Multiple sclerosis, susceptibility to; ms |
P08575
|
| #613205 | Muscular dystrophy, congenital, lmna-related |
P02545
|
| #159001 | Muscular dystrophy, limb-girdle, type 1b; lgmd1b |
P02545
|
| #607948 | Mycobacterium tuberculosis, susceptibility to |
P11473
|
| #159900 | Myoclonic dystonia |
P14416
|
| #202700 | Neutropenia, severe congenital, 1, autosomal dominant; scn1 |
P08246
|
| #601665 | Obesity |
P32245
P37231 |
| #164230 | Obsessive-compulsive disorder; ocd |
P31645
|
| #604715 | Orthostatic intolerance |
P23975
|
| #166350 | Osseous heteroplasia, progressive; poh |
P63092
|
| #259730 | Osteopetrosis, autosomal recessive 3; optb3 |
P00918
|
| #167000 | Ovarian cancer |
P04626
|
| #614594 | Palmoplantar keratoderma, mutilating, with periorificial keratotic plaques |
Q8NET8
|
| #260540 | Parkinson-dementia syndrome |
P10636
|
| #613135 | Parkinsonism-dystonia, infantile; pkdys |
Q01959
|
| #172700 | Pick disease of brain |
P10636
|
| #102200 | Pituitary adenoma, growth hormone-secreting |
P63092
|
| #103580 | Pseudohypoparathyroidism, type ia; php1a |
P63092
|
| #603233 | Pseudohypoparathyroidism, type ib; php1b |
P63092
|
| #612462 | Pseudohypoparathyroidism, type ic; php1c |
P63092
|
| #607276 | Resting heart rate, variation in |
P08588
|
| #275210 | Restrictive dermopathy, lethal |
P02545
|
| #608971 | Severe combined immunodeficiency, autosomal recessive, t cell-negative, b cell-positive, nk cell-positive |
P08575
|
| #609620 | Short qt syndrome 1; sqt1 |
Q12809
|
| #253300 | Spinal muscular atrophy, type i; sma1 |
Q16637
|
| #253550 | Spinal muscular atrophy, type ii; sma2 |
Q16637
|
| #253400 | Spinal muscular atrophy, type iii; sma3 |
Q16637
|
| #271150 | Spinal muscular atrophy, type iv; sma4 |
Q16637
|
| #601104 | Supranuclear palsy, progressive, 1; psnp1 |
P10636
|
| #190300 | Tremor, hereditary essential, 1; etm1 |
P35462
|
| #277440 | Vitamin d-dependent rickets, type 2a; vddr2a |
P11473
|
| #610379 | West nile virus, susceptibility to |
P51681
|
| #112100 | Yt blood group antigen |
P22303
|
KEGG DISEASE (63)
| KEGG | name | UniProt |
|---|---|---|
| H00033 | Adrenal carcinoma |
O00255
(related)
|
| H00034 | Carcinoid |
O00255
(related)
|
| H00045 | Malignant islet cell carcinoma |
O00255
(related)
|
| H00246 | Primary hyperparathyroidism |
O00255
(related)
|
| H01102 | Pituitary adenomas |
O00255
(related)
|
| H00016 | Oral cancer |
P00533
(related)
P00533 (marker) |
| H00017 | Esophageal cancer |
P00533
(related)
P35354 (related) |
| H00018 | Gastric cancer |
P00533
(related)
P04626 (related) |
| H00022 | Bladder cancer |
P00533
(related)
P04626 (related) |
| H00028 | Choriocarcinoma |
P00533
(related)
P03956 (related) P04626 (related) |
| H00030 | Cervical cancer |
P00533
(related)
P04626 (related) |
| H00042 | Glioma |
P00533
(related)
P00533 (marker) |
| H00055 | Laryngeal cancer |
P00533
(related)
P00533 (marker) |
| H00241 | Combined proximal and distal renal tubular acidosis (RTA type 3) |
P00918
(related)
|
| H00436 | Osteopetrosis |
P00918
(related)
|
| H00264 | Charcot-Marie-Tooth disease (CMT) |
P02545
(related)
|
| H00294 | Dilated cardiomyopathy (DCM) |
P02545
(related)
|
| H00420 | Familial partial lipodystrophy (FPL) |
P02545
(related)
P37231 (related) |
| H00563 | Emery-Dreifuss muscular dystrophy |
P02545
(related)
|
| H00590 | Congenital muscular dystrophies (CMD/MDC) |
P02545
(related)
|
| H00593 | Limb-girdle muscular dystrophy (LGMD) |
P02545
(related)
|
| H00601 | Hutchinson-Gilford progeria syndrome |
P02545
(related)
|
| H00663 | Restrictive dermopathy |
P02545
(related)
|
| H00665 | Mandibuloacral dysplasia |
P02545
(related)
|
| H01216 | Left ventricular noncompaction (LVNC) |
P02545
(related)
|
| H00026 | Endometrial Cancer |
P03372
(marker)
P04626 (related) Q92731 (marker) |
| H00599 | 46,XX disorders of sex development (Disorders related to androgen excess) |
P04150
(related)
|
| H00019 | Pancreatic cancer |
P04626
(related)
|
| H00027 | Ovarian cancer |
P04626
(related)
|
| H00031 | Breast cancer |
P04626
(related)
P04626 (marker) |
| H00046 | Cholangiocarcinoma |
P04626
(related)
P35354 (related) |
| H00093 | Combined immunodeficiencies (CIDs) |
P06239
(related)
|
| H00079 | Asthma |
P07550
(related)
|
| H00100 | Neutropenic disorders |
P08246
(related)
|
| H00091 | T-B+Severe combined immunodeficiencies (SCIDs) |
P08575
(related)
|
| H00036 | Osteosarcoma |
P08684
(marker)
|
| H00058 | Amyotrophic lateral sclerosis (ALS) |
P10636
(related)
Q13148 (related) |
| H00077 | Progressive supranuclear palsy (PSP) |
P10636
(related)
|
| H00078 | Frontotemporal lobar degeneration (FTLD) |
P10636
(related)
|
| H00342 | Tuberculosis |
P11473
(related)
|
| H00784 | Localized autosomal recessive hypotrichosis |
P11473
(related)
|
| H01143 | Vitamin D-dependent rickets |
P11473
(related)
|
| H01205 | Coumarin resistance |
P11712
(related)
|
| H00025 | Penile cancer |
P14780
(related)
P35354 (related) |
| H00479 | Metaphyseal dysplasias |
P14780
(related)
|
| H00457 | Primary hypertrophic osteoarthropathy (PHO) |
P15428
(related)
|
| H01246 | Isolated congenital nail clubbing (ICNC) |
P15428
(related)
|
| H00548 | Brunner syndrome |
P21397
(related)
|
| H00208 | Hyperbilirubinemia |
P22309
(related)
|
| H01031 | Orthostatic intolerance (OI) |
P23975
(related)
|
| H00490 | Diaphyseal dysplasia with anemia (Ghosal) |
P24557
(related)
|
| H01171 | Poor drug metabolism (PM) |
P33261
(related)
|
| H00032 | Thyroid cancer |
P37231
(related)
|
| H00409 | Type II diabetes mellitus |
P37231
(related)
|
| H00480 | Non-syndromic X-linked mental retardation |
P50052
(related)
|
| H00244 | Pseudohypoparathyroidism |
P63092
(related)
|
| H00441 | Progressive osseous heteroplasia (POH) |
P63092
(related)
|
| H00501 | Fibrous dysplasia, polyostotic |
P63092
(related)
|
| H00001 | Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) |
Q03164
(related)
Q03164 (marker) |
| H00002 | Acute lymphoblastic leukemia (ALL) (precursor T lymphoblastic leukemia) |
Q03164
(related)
|
| H00720 | Long QT syndrome |
Q12809
(related)
|
| H00725 | Short QT syndrome |
Q12809
(related)
|
| H00455 | Spinal muscular atrophy (SMA) |
Q16637
(related)
|
Diseases related to CTD interactions
13 disease in interactions with metabolites
| MESH or OMIM | name |
KNApSAcK
metabolite |
|---|---|---|
| D001930 | Brain Injuries |
C00000601
|
| D002375 | Catalepsy |
C00000601
|
| D018476 | Hypokinesia |
C00000601
|
| D020244 | Infarction, Middle Cerebral Artery |
C00000601
|
| D020734 | Parkinsonian Disorders |
C00000601
|
| D003371 | Cough |
C00000819
|
| D004487 | Edema |
C00000819
|
| D012640 | Seizures |
C00000819
|
| D003877 | Dermatitis, Contact |
C00002771
|
| D056486 | Drug-Induced Liver Injury |
C00002771
|
| D008113 | Liver Neoplasms |
C00002771
|
| D008114 | Liver Neoplasms, Experimental |
C00002771
|
| D015431 | Weight Loss |
C00002771
|