Species

KNApSAcK Entry

Organism name Enterococcus faecalis
Genus Enterococcus
Family Enterococcaceae
Kingdom Bacteria

NCBI taxonomy

Entry

Linked NCBI taxonomy name Enterococcus faecalis
Linked NCBI taxonomy ID 1351
Linked level species

Family

Family in NCBI taxonomy Enterococcaceae
ID 81852

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Bacteria
ID 2

Plant class

Plant class
ID

Metabolite list (5)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE
# of genes in
CTD interaction
/ related diseases
KCF-S
cluster
phytochemical
cluster
figure
C00007190 External link 512 (+)-Pinoresinol
CHEMBL267963
CHEMBL487611
CHEMBL460862
C103298
7 / 5 / 6 No. 38 No. 21
C00031032 External link 512 Pinoresinol diglucoside
/ (-)-Pinoresinol diglucoside
CHEMBL450911
CHEMBL573785
CHEMBL1712579
C013200
2 / 0 / 0 No. 152
C00000604 External link 512 (-)-Secoisolariciresinol
CHEMBL368347
C060283
2 / 1 / 1 1 / 0 No. 282 No. 21
C00000602 External link 512 (+)-Lariciresinol
CHEMBL518421
2 / 1 / 1 No. 700 No. 21
C00000702 External link 512 (-)-Enterodiol
CHEMBL471076
No. 3495

Human Protein / Gene in interactions

10 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
P10635 Cytochrome P450 2D6 Cytochrome P450 2D6 C00000602 C00000604 1 / 0
P08684 Cytochrome P450 3A4 Cytochrome P450 3A4 C00000602 C00000604 0 / 1
Q96QE3 ATPase family AAA domain-containing protein 5 Unclassified protein C00007190 C00031032 0 / 0
P37231 Peroxisome proliferator-activated receptor gamma NR1C3 C00007190 5 / 3
O75496 Geminin Unclassified protein C00031032 0 / 0
Q03181 Peroxisome proliferator-activated receptor delta NR1C2 C00007190 0 / 0
P35354 Prostaglandin G/H synthase 2 Oxidoreductase C00007190 0 / 3
P09917 Arachidonate 5-lipoxygenase Oxidoreductase C00007190 0 / 0
Q07869 Peroxisome proliferator-activated receptor alpha NR1C1 C00007190 0 / 0
Q9H0H5 Rac GTPase-activating protein 1 Unclassified protein C00007190 0 / 0

1 Gene in CTD interactions

gene gene name gene description KNApSAcK metabolite in interactions
8856 NR1I2, BXR, ONR1, PAR, PAR1, PAR2, PARq, PRR, PXR, SAR, SXR nuclear receptor subfamily 1, group I, member 2 C00000604

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (6)

OMIM preferred title UniProt
%606641 Body mass index; bmi P37231
#609338 Carotid intimal medial thickness 1 P37231
#608902 Drug metabolism, poor, cyp2d6-related P10635
#137800 Glioma susceptibility 1; glm1 P37231
#604367 Lipodystrophy, familial partial, type 3; fpld3 P37231
#601665 Obesity P37231

KEGG DISEASE (7)

KEGG name UniProt
H00036 Osteosarcoma P08684 (marker)
H00017 Esophageal cancer P35354 (related)
H00025 Penile cancer P35354 (related)
H00046 Cholangiocarcinoma P35354 (related)
H00032 Thyroid cancer P37231 (related)
H00409 Type II diabetes mellitus P37231 (related)
H00420 Familial partial lipodystrophy (FPL) P37231 (related)