Species

KNApSAcK Entry

Organism name Calopogonium mucunoides
Genus Calopogonium
Family Fabaceae
Kingdom Plantae

NCBI taxonomy

Entry

Linked NCBI taxonomy name Calopogonium mucunoides
Linked NCBI taxonomy ID 132433
Linked level species

Family

Family in NCBI taxonomy Fabaceae
ID 3803

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Viridiplantae
ID 33090

Plant class

Plant class rosids
ID 71275

Metabolite list (15)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE
# of genes in
CTD interaction
/ related diseases
KCF-S
cluster
phytochemical
cluster
figure
C00009417 External link 512 7,2',4',5'-Tetramethoxyisoflavone
CHEMBL478578
C091093
No. 8 No. 15
C00009433 External link 512 Calopogoniumisoflavone A
No. 24 No. 15
C00009496 External link 512 4'-O-Methylderrone
No. 24 No. 15
C00009495 External link 512 4'-O-methylalpinumisoflavone
No. 24 No. 15
C00009438 External link 512 Calopogoniumisoflavone B
/ 6'',6''-Dimethyl-3',4'-methylenedioxypyrano[2'',3'':7,8]isoflavone
No. 24 No. 15
C00009492 External link 512 Alpinumisoflavone
CHEMBL238628
C000154
3 / 1 / 1 1 / 0 No. 24 No. 15
C00009397 External link 512 Pseudobaptigenin methyl ether
/ 7-Methoxy-3',4'-methylenedioxyisoflavone
CHEMBL583578
11 / 32 / 53 No. 27 No. 15
C00009855 External link 512 7,8-Dimethoxy-3',4'-methylenedioxyisoflavone
No. 27 No. 15
C00009405 External link 512 Cabreuvin
/ 7,3',4'-Trimethoxyisoflavone
CHEMBL273891
7 / 10 / 6 No. 35 No. 15
C00009845 External link 512 8,4'-Dihydroxyisoflavone
No. 71 No. 15
C00010002 External link 512 Isoneorautenol
/ 3-Hydroxy-6'',6''-dimethylpyrano[2'',3'':9,8]pterocarpan
CHEMBL1098729
No. 135 No. 15
C00009640 External link 512 Homoedudiol
/ Sophorapterocarpan A
/ 3,9-Dihydroxy-8-prenylpterocarpan
CHEMBL1088321
1 / 0 / 0 No. 188 No. 15
C00009812 External link 512 7-Prenyloxy-3',4'-dimethoxyisoflavone
No. 354
C00009811 External link 512 7-Prenyloxy-3'-hydroxy-4'-methoxyisoflavone
No. 354
C00009822 External link 512 7-Prenyloxy-8-methoxy-3',4'-methylenedioxyisoflavone
No. 354

Human Protein / Gene in interactions

17 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
P18031 Tyrosine-protein phosphatase non-receptor type 1 Tyr C00009492 C00009640 0 / 0
P10636 Microtubule-associated protein tau Unclassified protein C00009397 C00009405 4 / 3
Q96QE3 ATPase family AAA domain-containing protein 5 Unclassified protein C00009397 C00009405 0 / 0
O15118 Niemann-Pick C1 protein Unclassified protein C00009397 C00009405 1 / 1
P51151 Ras-related protein Rab-9A Unclassified protein C00009397 C00009405 0 / 0
P43220 Glucagon-like peptide 1 receptor Glucagon-like peptide receptor C00009405 0 / 0
P38398 Breast cancer type 1 susceptibility protein Enzyme C00009405 4 / 2
Q92731 Estrogen receptor beta NR3A2 C00009492 0 / 1
P02545 Prelamin-A/C Unclassified protein C00009397 11 / 10
P37231 Peroxisome proliferator-activated receptor gamma NR1C3 C00009397 5 / 3
Q03181 Peroxisome proliferator-activated receptor delta NR1C2 C00009397 0 / 0
Q16637 Survival motor neuron protein Unclassified protein C00009397 4 / 1
P03372 Estrogen receptor NR3A1 C00009492 1 / 1
P04637 Cellular tumor antigen p53 Transcription Factor C00009397 7 / 37
Q16236 Nuclear factor erythroid 2-related factor 2 Unclassified protein C00009397 0 / 0
Q07869 Peroxisome proliferator-activated receptor alpha NR1C1 C00009397 0 / 0
Q13148 TAR DNA-binding protein 43 Unclassified protein C00009405 1 / 1

1 Gene in CTD interactions

gene gene name gene description KNApSAcK metabolite in interactions
3091 HIF1A, HIF-1A, HIF-1alpha, HIF1, HIF1-ALPHA, MOP1, PASD8, bHLHe78 hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) C00009492

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (38)

OMIM preferred title UniProt
#202300 Adrenocortical carcinoma, hereditary; adcc P04637
#612069 Amyotrophic lateral sclerosis 10, with or without frontotemporal dementia; als10 Q13148
#614740 Basal cell carcinoma, susceptibility to, 7; bcc7 P04637
%606641 Body mass index; bmi P37231
#114480 Breast cancer P38398
#604370 Breast-ovarian cancer, familial, susceptibility to, 1; brovca1 P38398
#115200 Cardiomyopathy, dilated, 1a; cmd1a P02545
#212112 Cardiomyopathy, dilated, with hypergonadotropic hypogonadism P02545
#609338 Carotid intimal medial thickness 1 P37231
#605588 Charcot-marie-tooth disease, axonal, type 2b1; cmt2b1 P02545
#181350 Emery-dreifuss muscular dystrophy 2, autosomal dominant; edmd2 P02545
#133239 Esophageal cancer P04637
#615363 Estrogen resistance; estrr P03372
#600274 Frontotemporal dementia; ftd P10636
#137800 Glioma susceptibility 1; glm1 P37231
#610140 Heart-hand syndrome, slovenian type P02545
#176670 Hutchinson-gilford progeria syndrome; hgps P02545
#151623 Li-fraumeni syndrome 1; lfs1 P04637
#151660 Lipodystrophy, familial partial, type 2; fpld2 P02545
#604367 Lipodystrophy, familial partial, type 3; fpld3 P37231
#211980 Lung cancer P04637
#248370 Mandibuloacral dysplasia with type a lipodystrophy; mada P02545
#613205 Muscular dystrophy, congenital, lmna-related P02545
#159001 Muscular dystrophy, limb-girdle, type 1b; lgmd1b P02545
#257220 Niemann-pick disease, type c1; npc1 O15118
#601665 Obesity P37231
#167000 Ovarian cancer P38398
#614320 Pancreatic cancer, susceptibility to, 4; pnca4 P38398
#260500 Papilloma of choroid plexus; cpp P04637
#260540 Parkinson-dementia syndrome P10636
#172700 Pick disease of brain P10636
#275210 Restrictive dermopathy, lethal P02545
#253300 Spinal muscular atrophy, type i; sma1 Q16637
#253550 Spinal muscular atrophy, type ii; sma2 Q16637
#253400 Spinal muscular atrophy, type iii; sma3 Q16637
#271150 Spinal muscular atrophy, type iv; sma4 Q16637
#275355 Squamous cell carcinoma, head and neck; hnscc P04637
#601104 Supranuclear palsy, progressive, 1; psnp1 P10636

KEGG DISEASE (53)

KEGG name UniProt
H00136 Niemann-Pick disease type C (NPC) O15118 (related)
H00264 Charcot-Marie-Tooth disease (CMT) P02545 (related)
H00294 Dilated cardiomyopathy (DCM) P02545 (related)
H00420 Familial partial lipodystrophy (FPL) P02545 (related)
P37231 (related)
H00563 Emery-Dreifuss muscular dystrophy P02545 (related)
H00590 Congenital muscular dystrophies (CMD/MDC) P02545 (related)
H00593 Limb-girdle muscular dystrophy (LGMD) P02545 (related)
H00601 Hutchinson-Gilford progeria syndrome P02545 (related)
H00663 Restrictive dermopathy P02545 (related)
H00665 Mandibuloacral dysplasia P02545 (related)
H01216 Left ventricular noncompaction (LVNC) P02545 (related)
H00026 Endometrial Cancer P03372 (marker)
P04637 (related)
Q92731 (marker)
H00004 Chronic myeloid leukemia (CML) P04637 (related)
H00005 Chronic lymphocytic leukemia (CLL) P04637 (related)
H00006 Hairy-cell leukemia P04637 (related)
H00008 Burkitt lymphoma P04637 (related)
H00009 Adult T-cell leukemia P04637 (related)
H00010 Multiple myeloma P04637 (related)
H00013 Small cell lung cancer P04637 (related)
H00014 Non-small cell lung cancer P04637 (related)
H00015 Malignant pleural mesothelioma P04637 (related)
H00016 Oral cancer P04637 (related)
P04637 (marker)
H00017 Esophageal cancer P04637 (related)
P04637 (marker)
H00018 Gastric cancer P04637 (related)
H00019 Pancreatic cancer P04637 (related)
P04637 (marker)
H00020 Colorectal cancer P04637 (related)
P04637 (marker)
H00022 Bladder cancer P04637 (related)
H00025 Penile cancer P04637 (related)
P04637 (marker)
H00027 Ovarian cancer P04637 (related)
P38398 (related)
H00028 Choriocarcinoma P04637 (related)
H00029 Vulvar cancer P04637 (related)
H00031 Breast cancer P04637 (related)
P38398 (related)
H00032 Thyroid cancer P04637 (related)
P37231 (related)
H00033 Adrenal carcinoma P04637 (related)
H00036 Osteosarcoma P04637 (related)
H00038 Malignant melanoma P04637 (related)
H00039 Basal cell carcinoma P04637 (related)
H00040 Squamous cell carcinoma P04637 (related)
H00041 Kaposi's sarcoma P04637 (related)
H00042 Glioma P04637 (related)
P04637 (marker)
H00044 Cancer of the anal canal P04637 (related)
H00046 Cholangiocarcinoma P04637 (related)
H00047 Gallbladder cancer P04637 (related)
H00048 Hepatocellular carcinoma P04637 (related)
H00055 Laryngeal cancer P04637 (related)
P04637 (marker)
H00881 Li-Fraumeni syndrome P04637 (related)
H01007 Choroid plexus papilloma P04637 (related)
H00021 Renal cell carcinoma P04637 (marker)
H00058 Amyotrophic lateral sclerosis (ALS) P10636 (related)
Q13148 (related)
H00077 Progressive supranuclear palsy (PSP) P10636 (related)
H00078 Frontotemporal lobar degeneration (FTLD) P10636 (related)
H00409 Type II diabetes mellitus P37231 (related)
H00455 Spinal muscular atrophy (SMA) Q16637 (related)