PCIDB

KNApSAcK Metabolite C00009492

Metabolite

KNApSAcK Entry

id C00009492
Name Alpinumisoflavone
CAS RN 34086-50-5
Standard InChI InChI=1S/C20H16O5/c1-20(2)8-7-13-15(25-20)9-16-17(18(13)22)19(23)14(10-24-16)11-3-5-12(21)6-4-11/h3-10,21-22H,1-2H3
Standard InChI (Main Layer) InChI=1S/C20H16O5/c1-20(2)8-7-13-15(25-20)9-16-17(18(13)22)19(23)14(10-24-16)11-3-5-12(21)6-4-11/h3-10,21-22H,1-2H3

Cluster

Phytochemical cluster No. 15
KCF-S cluster No. 24

Link

ChEMBL

By standard InChI CHEMBL238628
By standard InChI Main Layer CHEMBL238628

KEGG

By LinkDB

CTD

By CAS RN C000154

Human Protein / Gene in interaction

3 ChEMBL Protein in interactions

accession description class description compound assay ID (# of activities) # of diseases
(OMIM / KEGG)
P18031 Tyrosine-protein phosphatase non-receptor type 1 Tyr CHEMBL238628 CHEMBL972808 (1)
0 / 0
Q92731 Estrogen receptor beta NR3A2 CHEMBL238628 CHEMBL1106814 (1)
0 / 1
P03372 Estrogen receptor NR3A1 CHEMBL238628 CHEMBL1106813 (1)
1 / 1

CTD interaction (2)

compound gene gene name gene description interaction interaction type form reference
pmid
C000154 3091 HIF1A
HIF-1A
HIF-1alpha
HIF1
HIF1-ALPHA
MOP1
PASD8
bHLHe78
hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) alpinumisoflavone inhibits the reaction [1,10-phenanthroline deficiency results in increased activity of HIF1A protein] decreases reaction
/ increases activity
protein 19091749
C000154 3091 HIF1A
HIF-1A
HIF-1alpha
HIF1
HIF1-ALPHA
MOP1
PASD8
bHLHe78
hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) alpinumisoflavone inhibits the reaction [Oxygen deficiency results in increased activity of HIF1A protein] decreases reaction
/ increases activity
protein 19091749

Related Disease

Diseases related to proteins in ChEMBL interactions

OMIM (1)

OMIM preferred title UniProt
#615363 Estrogen resistance; estrr P03372

KEGG DISEASE (1)

KEGG disease name UniProt
H00026 Endometrial Cancer P03372 (marker)
Q92731 (marker)