| Organism name | Forsythia koreana | 
|---|---|
| Genus | Forsythia | 
| Family | Oleaceae | 
| Kingdom | Plantae | 
| Linked NCBI taxonomy name | Forsythia viridissima var. koreana | 
|---|---|
| Linked NCBI taxonomy ID | 205692 | 
| Linked level | varietas | 
| Family in NCBI taxonomy | Oleaceae | 
|---|---|
| ID | 4144 | 
| Kingdom (Superkingdom) in NCBI taxonomy | Viridiplantae | 
|---|---|
| ID | 33090 | 
| Plant class | asterids | 
|---|---|
| ID | 71274 | 
| KNApSAcK ID | name | ChEMBL link | CTD link | # of proteins in ChEMBL interaction / related OMIM / related KEGG DISEASE | # of genes in CTD interaction / related diseases | KCF-S cluster | phytochemical cluster | figure | 
|---|---|---|---|---|---|---|---|---|
| C00002744   | Forsythiaside / Forsythoside A | CHEMBL504363 | C058049 | 1 / 0 / 0 | No. 33 |   | ||
| C00007190   | (+)-Pinoresinol | CHEMBL267963 CHEMBL487611 CHEMBL460862 | C103298 | 7 / 5 / 6 | No. 38 | No. 21 |   | |
| C00000647   | (+)-Phillygenin | CHEMBL457587 | No. 38 | No. 21 |   | |||
| C00000609   | (-)-Arctigenin | CHEMBL369142 CHEMBL435734 CHEMBL1966556 | C071942 | 13 / 7 / 6 | No. 223 | No. 21 |   | |
| C00000606   | (-)-Matairesinol | CHEMBL425148 | C068935 | 1 / 0 / 0 | No. 223 | No. 21 |   | |
| C00000604   | (-)-Secoisolariciresinol | CHEMBL368347 | C060283 | 2 / 1 / 1 | 1 / 0 | No. 282 | No. 21 |   | 
| accession | description | class description | KNApSAcK metabolite in interactions | # of diseases (OMIM / KEGG) | 
|---|---|---|---|---|
| P10635 | Cytochrome P450 2D6 | Cytochrome P450 2D6 | C00000604 C00000609 | 1 / 0 | 
| P08684 | Cytochrome P450 3A4 | Cytochrome P450 3A4 | C00000604 C00000609 | 0 / 1 | 
| P43220 | Glucagon-like peptide 1 receptor | Glucagon-like peptide receptor | C00000609 | 0 / 0 | 
| P09917 | Arachidonate 5-lipoxygenase | Oxidoreductase | C00007190 | 0 / 0 | 
| P35354 | Prostaglandin G/H synthase 2 | Oxidoreductase | C00007190 | 0 / 3 | 
| P17252 | Protein kinase C alpha type | Alpha | C00002744 | 0 / 0 | 
| Q03181 | Peroxisome proliferator-activated receptor delta | NR1C2 | C00007190 | 0 / 0 | 
| P11712 | Cytochrome P450 2C9 | Cytochrome P450 2C9 | C00000609 | 0 / 1 | 
| P04278 | Sex hormone-binding globulin | Secreted protein | C00000606 | 0 / 0 | 
| P84022 | Mothers against decapentaplegic homolog 3 | Unclassified protein | C00000609 | 2 / 0 | 
| P51151 | Ras-related protein Rab-9A | Unclassified protein | C00000609 | 0 / 0 | 
| Q99700 | Ataxin-2 | Unclassified protein | C00000609 | 1 / 1 | 
| P37231 | Peroxisome proliferator-activated receptor gamma | NR1C3 | C00007190 | 5 / 3 | 
| P28482 | Mitogen-activated protein kinase 1 | Erk | C00000609 | 0 / 0 | 
| P05177 | Cytochrome P450 1A2 | Cytochrome P450 1A2 | C00000609 | 0 / 0 | 
| O15118 | Niemann-Pick C1 protein | Unclassified protein | C00000609 | 1 / 1 | 
| Q96QE3 | ATPase family AAA domain-containing protein 5 | Unclassified protein | C00007190 | 0 / 0 | 
| P33261 | Cytochrome P450 2C19 | Cytochrome P450 2C19 | C00000609 | 1 / 1 | 
| Q02750 | Dual specificity mitogen-activated protein kinase kinase 1 | Ste7 | C00000609 | 1 / 1 | 
| Q9UNA4 | DNA polymerase iota | Enzyme | C00000609 | 0 / 0 | 
| Q07869 | Peroxisome proliferator-activated receptor alpha | NR1C1 | C00007190 | 0 / 0 | 
| Q9H0H5 | Rac GTPase-activating protein 1 | Unclassified protein | C00007190 | 0 / 0 | 
| gene | gene name | gene description | KNApSAcK metabolite in interactions | 
|---|---|---|---|
| 8856 | NR1I2, BXR, ONR1, PAR, PAR1, PAR2, PARq, PRR, PXR, SAR, SXR | nuclear receptor subfamily 1, group I, member 2 | C00000604 | 
| OMIM | preferred title | UniProt | 
|---|---|---|
| %606641 | Body mass index; bmi | P37231 | 
| #615279 | Cardiofaciocutaneous syndrome 3; cfc3 | Q02750 | 
| #609338 | Carotid intimal medial thickness 1 | P37231 | 
| #114500 | Colorectal cancer; crc | P84022 | 
| #609535 | Drug metabolism, poor, cyp2c19-related | P33261 | 
| #608902 | Drug metabolism, poor, cyp2d6-related | P10635 | 
| #137800 | Glioma susceptibility 1; glm1 | P37231 | 
| #604367 | Lipodystrophy, familial partial, type 3; fpld3 | P37231 | 
| #613795 | Loeys-dietz syndrome, type 3; lds3 | P84022 | 
| #257220 | Niemann-pick disease, type c1; npc1 | O15118 | 
| #601665 | Obesity | P37231 | 
| #183090 | Spinocerebellar ataxia 2; sca2 | Q99700 | 
| KEGG | name | UniProt | 
|---|---|---|
| H00136 | Niemann-Pick disease type C (NPC) | O15118
                            (related) | 
| H00036 | Osteosarcoma | P08684
                            (marker) | 
| H01205 | Coumarin resistance | P11712
                            (related) | 
| H01171 | Poor drug metabolism (PM) | P33261
                            (related) | 
| H00017 | Esophageal cancer | P35354
                            (related) | 
| H00025 | Penile cancer | P35354
                            (related) | 
| H00046 | Cholangiocarcinoma | P35354
                            (related) | 
| H00032 | Thyroid cancer | P37231
                            (related) | 
| H00409 | Type II diabetes mellitus | P37231
                            (related) | 
| H00420 | Familial partial lipodystrophy (FPL) | P37231
                            (related) | 
| H00523 | Noonan syndrome and related disorders | Q02750
                            (related) | 
| H00063 | Spinocerebellar ataxia (SCA) | Q99700
                            (related) |