Elsholtzia rugulosa Hemsl.
Species
KNApSAcK Entry
| Organism name | Elsholtzia rugulosa Hemsl. |
|---|---|
| Genus | Elsholtzia |
| Family | Labiatae |
| Kingdom | Plantae |
NCBI taxonomy
Entry
| Linked NCBI taxonomy name | Elsholtzia |
|---|---|
| Linked NCBI taxonomy ID | 41225 |
| Linked level | genus |
Family
| Family in NCBI taxonomy | Lamiaceae |
|---|---|
| ID | 4136 |
Kingdom (Superkingdom)
| Kingdom (Superkingdom) in NCBI taxonomy | Viridiplantae |
|---|---|
| ID | 33090 |
Plant class
| Plant class | asterids |
|---|---|
| ID | 71274 |
Metabolite list (8)
| KNApSAcK ID | name | ChEMBL link | CTD link |
# of proteins in
ChEMBL interaction / related OMIM / related KEGG DISEASE |
# of genes in
CTD interaction / related diseases |
KCF-S
cluster |
phytochemical
cluster |
figure |
|---|---|---|---|---|---|---|---|---|
C00004274
|
Luteolin 3'-O-beta-D-glucuronide
|
No. 2 | No. 15 |
|
||||
|
C00005373
|
Hirsutrin
/ Isoquercetin / Isoquercetrin / (-)-Isoquercetrin / Quercetin 3-glucoside / Quercetin 3-O-beta-D-glucoside / Quercetin-3-O-beta-D-glucopyranoside / Quercetin 3-O-beta-D-glucopyranoside / (-)-Quercetin-3-O-beta-D-glucopyranoside |
CHEMBL33027
CHEMBL309323 CHEMBL250450 CHEMBL251254 CHEMBL457304 CHEMBL1098724 CHEMBL2337335 CHEMBL2337336 |
38 / 43 / 34 | No. 2 | No. 15 |
|
||
|
C00001454
|
Prunasin
/ (-)-Prunasin / (2R)-Prunasin / (-)-(2R)-Prunasin |
CHEMBL1778417
|
No. 45 | No. 72 |
|
|||
|
C00000674
|
Luteolin
|
CHEMBL151
|
D047311
|
99 / 91 / 95 | 76 / 6 | No. 71 | No. 15 |
|
|
C00001437
|
Amygdalin
/ (R)-Amygdalin |
CHEMBL515712
CHEMBL461727 CHEMBL1967951 CHEMBL2007233 |
D000678
|
92 / 37 / 31 | No. 128 | No. 72 |
|
|
|
C00030711
|
6'-O-.beta.-D-Apiofuranosyldianthoside
/ Maltol 6'-O-beta-D-apiofuranosyl-beta-D-glucopyranoside |
CHEMBL2335272
|
No. 267 |
|
||||
|
C00002770
|
Rosmarinic acid
|
CHEMBL66966
CHEMBL324842 CHEMBL1315100 CHEMBL2111558 |
48 / 35 / 38 | No. 749 |
|
|||
|
C00000615
|
Caffeic acid
|
CHEMBL145
CHEMBL1320034 |
68 / 64 / 63 | No. 904 | No. 6 |
|
Human Protein / Gene in interactions
221 ChEMBL Protein in interactions
| accession | description | class description | KNApSAcK metabolite in interactions |
# of diseases
(OMIM / KEGG) |
|---|---|---|---|---|
| P35354 | Prostaglandin G/H synthase 2 | Oxidoreductase | C00000615 C00000674 C00001437 C00002770 C00005373 | 0 / 3 |
| P27695 | DNA-(apurinic or apyrimidinic site) lyase | Enzyme | C00000615 C00000674 C00002770 C00005373 | 0 / 0 |
| P05177 | Cytochrome P450 1A2 | Cytochrome P450 1A2 | C00000615 C00000674 C00001437 C00002770 | 0 / 0 |
| P33261 | Cytochrome P450 2C19 | Cytochrome P450 2C19 | C00000615 C00000674 C00001437 C00002770 | 1 / 1 |
| P23219 | Prostaglandin G/H synthase 1 | Oxidoreductase | C00000615 C00000674 C00001437 C00002770 | 0 / 0 |
| P11712 | Cytochrome P450 2C9 | Cytochrome P450 2C9 | C00000615 C00000674 C00001437 C00002770 | 0 / 1 |
| P08684 | Cytochrome P450 3A4 | Cytochrome P450 3A4 | C00000615 C00000674 C00001437 C00002770 | 0 / 1 |
| Q9UIF8 | Bromodomain adjacent to zinc finger domain protein 2B | Unclassified protein | C00000615 C00000674 C00002770 C00005373 | 0 / 0 |
| O94925 | Glutaminase kidney isoform, mitochondrial | Enzyme | C00000615 C00000674 C00002770 C00005373 | 0 / 0 |
| P10253 | Lysosomal alpha-glucosidase | Hydrolase | C00000615 C00000674 C00002770 C00005373 | 1 / 1 |
| Q96KQ7 | Histone-lysine N-methyltransferase EHMT2 | Enzyme | C00000615 C00000674 C00002770 C00005373 | 0 / 0 |
| P03956 | Interstitial collagenase | M10A | C00000615 C00000674 C00001437 C00002770 | 0 / 1 |
| B2RXH2 | Lysine-specific demethylase 4E | Enzyme | C00000615 C00000674 C00002770 C00005373 | 0 / 0 |
| P10636 | Microtubule-associated protein tau | Unclassified protein | C00000615 C00000674 C00002770 C00005373 | 4 / 3 |
| P10635 | Cytochrome P450 2D6 | Cytochrome P450 2D6 | C00000615 C00000674 C00001437 C00002770 | 1 / 0 |
| P06746 | DNA polymerase beta | Enzyme | C00000615 C00000674 C00002770 C00005373 | 0 / 0 |
| Q9UBT6 | DNA polymerase kappa | Enzyme | C00000615 C00000674 C00002770 C00005373 | 0 / 0 |
| P06280 | Alpha-galactosidase A | Enzyme | C00000615 C00000674 C00005373 | 1 / 1 |
| P14679 | Tyrosinase | Oxidoreductase | C00000615 C00000674 C00005373 | 4 / 2 |
| P06239 | Tyrosine-protein kinase Lck | Src | C00000674 C00001437 C00002770 | 0 / 1 |
| P02545 | Prelamin-A/C | Unclassified protein | C00000615 C00000674 C00005373 | 11 / 10 |
| Q9Y253 | DNA polymerase eta | Enzyme | C00000674 C00002770 C00005373 | 1 / 1 |
| P04062 | Glucosylceramidase | Enzyme | C00000674 C00002770 C00005373 | 6 / 4 |
| Q9NUW8 | Tyrosyl-DNA phosphodiesterase 1 | Enzyme | C00000615 C00000674 C00002770 | 1 / 1 |
| P15121 | Aldose reductase | Enzyme | C00000615 C00002770 C00005373 | 0 / 0 |
| O75164 | Lysine-specific demethylase 4A | Enzyme | C00000615 C00000674 C00002770 | 0 / 0 |
| Q9UNA4 | DNA polymerase iota | Enzyme | C00000674 C00002770 C00005373 | 0 / 0 |
| P39748 | Flap endonuclease 1 | Enzyme | C00000674 C00002770 C00005373 | 0 / 0 |
| Q13951 | Core-binding factor subunit beta | Unclassified protein | C00000674 C00002770 C00005373 | 0 / 1 |
| P28482 | Mitogen-activated protein kinase 1 | Erk | C00000615 C00001437 C00005373 | 0 / 0 |
| Q01196 | Runt-related transcription factor 1 | Unclassified protein | C00000674 C00002770 C00005373 | 1 / 4 |
| P03372 | Estrogen receptor | NR3A1 | C00000615 C00000674 C00001437 | 1 / 1 |
| P14780 | Matrix metalloproteinase-9 | M10A | C00000615 C00000674 C00001437 | 2 / 2 |
| P10828 | Thyroid hormone receptor beta | NR1A2 | C00000615 C00000674 C00002770 | 3 / 1 |
| P15428 | 15-hydroxyprostaglandin dehydrogenase [NAD(+)] | Enzyme | C00000615 C00000674 C00002770 | 2 / 2 |
| P47989 | Xanthine dehydrogenase/oxidase | Oxidoreductase | C00000615 C00000674 C00005373 | 1 / 1 |
| Q99714 | 3-hydroxyacyl-CoA dehydrogenase type-2 | Enzyme | C00000615 C00000674 C00002770 | 3 / 3 |
| Q9NR56 | Muscleblind-like protein 1 | Unclassified protein | C00000674 C00002770 C00005373 | 1 / 0 |
| P16473 | Thyrotropin receptor | Glycohormone receptor | C00000615 C00000674 | 3 / 2 |
| Q9UNQ0 | ATP-binding cassette sub-family G member 2 | ATP binding cassette | C00000674 C00005373 | 2 / 0 |
| Q96QE3 | ATPase family AAA domain-containing protein 5 | Unclassified protein | C00000674 C00002770 | 0 / 0 |
| P00918 | Carbonic anhydrase 2 | Lyase | C00000615 C00001437 | 1 / 2 |
| P08253 | 72 kDa type IV collagenase | M10A | C00000615 C00000674 | 1 / 3 |
| P21397 | Amine oxidase [flavin-containing] A | Oxidoreductase | C00000674 C00001437 | 1 / 1 |
| P22303 | Acetylcholinesterase | Hydrolase | C00000674 C00001437 | 1 / 0 |
| P35372 | Mu-type opioid receptor | Opioid receptor | C00001437 C00005373 | 0 / 0 |
| Q13093 | Platelet-activating factor acetylhydrolase | Enzyme | C00000615 C00002770 | 3 / 0 |
| Q12794 | Hyaluronidase-1 | Enzyme | C00000615 C00002770 | 1 / 2 |
| P18825 | Alpha-2C adrenergic receptor | Adrenergic receptor | C00001437 C00005373 | 0 / 0 |
| P04150 | Glucocorticoid receptor | NR3C1 | C00000674 C00001437 | 0 / 1 |
| O94782 | Ubiquitin carboxyl-terminal hydrolase 1 | Enzyme | C00000674 C00002770 | 0 / 0 |
| Q12809 | Potassium voltage-gated channel subfamily H member 2 | KCNH, Kv10-12.x (Ether-a-go-go) | C00000615 C00001437 | 2 / 2 |
| P27338 | Amine oxidase [flavin-containing] B | Oxidoreductase | C00000674 C00001437 | 0 / 0 |
| P46063 | ATP-dependent DNA helicase Q1 | Enzyme | C00000674 C00002770 | 0 / 0 |
| O00255 | Menin | Unclassified protein | C00000615 C00000674 | 2 / 5 |
| P41143 | Delta-type opioid receptor | Opioid receptor | C00001437 C00005373 | 0 / 0 |
| O75496 | Geminin | Unclassified protein | C00000674 C00005373 | 0 / 0 |
| Q16637 | Survival motor neuron protein | Unclassified protein | C00000674 C00005373 | 4 / 1 |
| P06241 | Tyrosine-protein kinase Fyn | Src | C00001437 C00002770 | 0 / 0 |
| Q16665 | Hypoxia-inducible factor 1-alpha | Transcription Factor | C00000615 C00000674 | 0 / 0 |
| Q9NPH5 | NADPH oxidase 4 | Enzyme | C00000674 C00005373 | 0 / 0 |
| P36888 | Receptor-type tyrosine-protein kinase FLT3 | Pdgfr | C00000674 C00005373 | 1 / 1 |
| P00352 | Retinal dehydrogenase 1 | Enzyme | C00000615 C00000674 | 0 / 0 |
| P41145 | Kappa-type opioid receptor | Opioid receptor | C00001437 C00005373 | 0 / 0 |
| Q03164 | Histone-lysine N-methyltransferase 2A | Enzyme | C00000615 C00000674 | 1 / 2 |
| P54132 | Bloom syndrome protein | Enzyme | C00000674 C00002770 | 1 / 2 |
| P00533 | Epidermal growth factor receptor | TK tyrosine-protein kinase EGFR subfamily | C00000615 C00001437 | 1 / 8 |
| P83916 | Chromobox protein homolog 1 | Unclassified protein | C00001437 C00002770 | 0 / 0 |
| P07451 | Carbonic anhydrase 3 | Lyase | C00000615 | 0 / 0 |
| P51570 | Galactokinase | Enzyme | C00000674 | 1 / 1 |
| P11387 | DNA topoisomerase 1 | Isomerase | C00000674 | 0 / 0 |
| P11388 | DNA topoisomerase 2-alpha | Isomerase | C00000674 | 0 / 0 |
| P14416 | D(2) dopamine receptor | Dopamine receptor | C00001437 | 2 / 0 |
| Q9GZT9 | Egl nine homolog 1 | Enzyme | C00000615 | 1 / 1 |
| P37288 | Vasopressin V1a receptor | Vasopressin and oxytocin receptor | C00001437 | 0 / 0 |
| P07237 | Protein disulfide-isomerase | Enzyme | C00005373 | 0 / 0 |
| Q9Y271 | Cysteinyl leukotriene receptor 1 | Leukotriene receptor | C00001437 | 0 / 0 |
| P29274 | Adenosine receptor A2a | Adenosine receptor | C00001437 | 0 / 0 |
| P23280 | Carbonic anhydrase 6 | Lyase | C00000615 | 0 / 0 |
| P25929 | Neuropeptide Y receptor type 1 | Neuropeptide Y receptor | C00001437 | 0 / 0 |
| P01730 | T-cell surface glycoprotein CD4 | Surface antigen | C00001437 | 1 / 0 |
| Q9Y3R4 | Sialidase-2 | Enzyme | C00000674 | 0 / 0 |
| P50052 | Type-2 angiotensin II receptor | Angiotensin receptor | C00001437 | 1 / 1 |
| O15296 | Arachidonate 15-lipoxygenase B | Enzyme | C00000674 | 0 / 0 |
| P17948 | Vascular endothelial growth factor receptor 1 | Vegfr | C00001437 | 0 / 0 |
| P41968 | Melanocortin receptor 3 | Melanocortin receptor | C00001437 | 1 / 0 |
| Q9ULX7 | Carbonic anhydrase 14 | Lyase | C00000615 | 0 / 0 |
| Q15078 | Cyclin-dependent kinase 5 activator 1 | REG serine/threonine protein kinase family | C00000674 | 0 / 0 |
| O43570 | Carbonic anhydrase 12 | Lyase | C00000615 | 1 / 2 |
| Q00535 | Cyclin-dependent kinase 5 | Cdk5 | C00000674 | 0 / 0 |
| P11509 | Cytochrome P450 2A6 | Cytochrome P450 2A6 | C00001437 | 0 / 0 |
| Q08209 | Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform | Ser_Thr | C00001437 | 0 / 0 |
| P42330 | Aldo-keto reductase family 1 member C3 | Enzyme | C00000615 | 0 / 0 |
| Q8TDS4 | Hydroxycarboxylic acid receptor 2 | Hydroxycarboxylic acid receptor | C00000615 | 0 / 0 |
| P24941 | Cyclin-dependent kinase 2 | Cdc2 | C00000674 | 0 / 0 |
| Q92830 | Histone acetyltransferase KAT2A | Enzyme | C00002770 | 0 / 0 |
| P84022 | Mothers against decapentaplegic homolog 3 | Unclassified protein | C00000674 | 2 / 0 |
| P25024 | C-X-C chemokine receptor type 1 | CXC chemokine receptor | C00001437 | 0 / 0 |
| P38398 | Breast cancer type 1 susceptibility protein | Enzyme | C00000674 | 4 / 2 |
| P04035 | 3-hydroxy-3-methylglutaryl-coenzyme A reductase | Oxidoreductase | C00001437 | 0 / 0 |
| P08913 | Alpha-2A adrenergic receptor | Adrenergic receptor | C00001437 | 0 / 0 |
| P21917 | D(4) dopamine receptor | Dopamine receptor | C00001437 | 0 / 0 |
| P30988 | Calcitonin receptor | Calcitonin receptor | C00001437 | 0 / 0 |
| P35462 | D(3) dopamine receptor | Dopamine receptor | C00001437 | 1 / 0 |
| P49327 | Fatty acid synthase | Transferase | C00000674 | 0 / 0 |
| Q92731 | Estrogen receptor beta | NR3A2 | C00001437 | 0 / 1 |
| P41595 | 5-hydroxytryptamine receptor 2B | Serotonin receptor | C00001437 | 0 / 0 |
| P08183 | Multidrug resistance protein 1 | drug | C00000674 | 1 / 0 |
| P25101 | Endothelin-1 receptor | Endothelin receptor | C00001437 | 0 / 0 |
| P30411 | B2 bradykinin receptor | Bradykinin receptor | C00001437 | 0 / 0 |
| P32245 | Melanocortin receptor 4 | Melanocortin receptor | C00001437 | 1 / 0 |
| P00915 | Carbonic anhydrase 1 | Lyase | C00000615 | 0 / 0 |
| P32238 | Cholecystokinin receptor type A | Cholecystokinin receptor | C00001437 | 0 / 0 |
| P08311 | Cathepsin G | S1A | C00001437 | 0 / 0 |
| Q99720 | Sigma non-opioid intracellular receptor 1 | Membrane receptor | C00001437 | 1 / 0 |
| P40763 | Signal transducer and activator of transcription 3 | Transcription Factor | C00002770 | 1 / 2 |
| P09874 | Poly [ADP-ribose] polymerase 1 | Enzyme | C00000674 | 0 / 0 |
| P51452 | Dual specificity protein phosphatase 3 | Ser_Thr_Tyr | C00000615 | 0 / 0 |
| P32241 | Vasoactive intestinal polypeptide receptor 1 | Vasoactive intestinal peptide receptor | C00001437 | 0 / 0 |
| P04798 | Cytochrome P450 1A1 | Cytochrome P450 1A1 | C00000674 | 0 / 0 |
| P09923 | Intestinal-type alkaline phosphatase | Enzyme | C00005373 | 0 / 0 |
| P05186 | Alkaline phosphatase, tissue-nonspecific isozyme | Enzyme | C00005373 | 3 / 1 |
| P11309 | Serine/threonine-protein kinase pim-1 | Pim | C00000674 | 0 / 0 |
| P11021 | 78 kDa glucose-regulated protein | Unclassified protein | C00000674 | 0 / 0 |
| Q00534 | Cyclin-dependent kinase 6 | CMGC serine/threonine protein kinase family | C00000674 | 1 / 0 |
| P13945 | Beta-3 adrenergic receptor | Adrenergic receptor | C00001437 | 0 / 0 |
| P08172 | Muscarinic acetylcholine receptor M2 | Acetylcholine receptor | C00001437 | 2 / 0 |
| P11229 | Muscarinic acetylcholine receptor M1 | Acetylcholine receptor | C00001437 | 0 / 0 |
| P08912 | Muscarinic acetylcholine receptor M5 | Acetylcholine receptor | C00001437 | 0 / 0 |
| P21554 | Cannabinoid receptor 1 | Cannabinoid receptor | C00001437 | 0 / 0 |
| P31645 | Sodium-dependent serotonin transporter | Serotonin | C00001437 | 2 / 0 |
| P04626 | Receptor tyrosine-protein kinase erbB-2 | TK tyrosine-protein kinase EGFR subfamily | C00001437 | 5 / 9 |
| P20309 | Muscarinic acetylcholine receptor M3 | Acetylcholine receptor | C00001437 | 1 / 0 |
| Q16678 | Cytochrome P450 1B1 | Cytochrome P450 1B1 | C00000674 | 4 / 4 |
| P21452 | Substance-K receptor | Neurokinin receptor | C00001437 | 0 / 0 |
| P12931 | Proto-oncogene tyrosine-protein kinase Src | Src | C00002770 | 0 / 0 |
| P06276 | Cholinesterase | Hydrolase | C00000674 | 0 / 0 |
| P51679 | C-C chemokine receptor type 4 | CC chemokine receptor | C00001437 | 0 / 0 |
| P51681 | C-C chemokine receptor type 5 | CC chemokine receptor | C00001437 | 3 / 0 |
| P50406 | 5-hydroxytryptamine receptor 6 | Serotonin receptor | C00001437 | 0 / 0 |
| Q01959 | Sodium-dependent dopamine transporter | Dopamine | C00001437 | 1 / 0 |
| P04745 | Alpha-amylase 1 | Enzyme | C00000674 | 0 / 0 |
| P45452 | Collagenase 3 | M10A | C00000674 | 1 / 1 |
| P18054 | Arachidonate 12-lipoxygenase, 12S-type | Enzyme | C00000674 | 2 / 0 |
| P35236 | Tyrosine-protein phosphatase non-receptor type 7 | Tyr | C00000615 | 0 / 0 |
| P41597 | C-C chemokine receptor type 2 | CC chemokine receptor | C00001437 | 1 / 0 |
| P35367 | Histamine H1 receptor | Histamine receptor | C00001437 | 0 / 0 |
| P10696 | Alkaline phosphatase, placental-like | Enzyme | C00005373 | 0 / 1 |
| P08575 | Receptor-type tyrosine-protein phosphatase C | Enzyme | C00001437 | 2 / 1 |
| P25021 | Histamine H2 receptor | Histamine receptor | C00001437 | 0 / 0 |
| Q16790 | Carbonic anhydrase 9 | Lyase | C00000615 | 0 / 1 |
| P07550 | Beta-2 adrenergic receptor | Adrenergic receptor | C00001437 | 0 / 1 |
| O75604 | Ubiquitin carboxyl-terminal hydrolase 2 | Enzyme | C00002770 | 0 / 0 |
| O95271 | Tankyrase-1 | Enzyme | C00000674 | 0 / 0 |
| P51692 | Signal transducer and activator of transcription 5B | Unclassified protein | C00002770 | 1 / 1 |
| Q04828 | Aldo-keto reductase family 1 member C1 | Enzyme | C00000615 | 0 / 0 |
| P28907 | ADP-ribosyl cyclase 1 | Enzyme | C00000674 | 0 / 1 |
| Q01453 | Peripheral myelin protein 22 | Unclassified protein | C00000615 | 5 / 2 |
| Q13526 | Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 | Enzyme | C00000674 | 0 / 0 |
| Q9H2K2 | Tankyrase-2 | Enzyme | C00000674 | 0 / 0 |
| O14763 | Tumor necrosis factor receptor superfamily member 10B | Unclassified protein | C00000674 | 1 / 0 |
| O76074 | cGMP-specific 3',5'-cyclic phosphodiesterase | PDE_5A | C00001437 | 0 / 0 |
| P39900 | Macrophage metalloelastase | M10A | C00000674 | 0 / 0 |
| P08588 | Beta-1 adrenergic receptor | Adrenergic receptor | C00001437 | 1 / 0 |
| P27361 | Mitogen-activated protein kinase 3 | Erk | C00001437 | 0 / 0 |
| P28223 | 5-hydroxytryptamine receptor 2A | Serotonin receptor | C00001437 | 0 / 0 |
| P28335 | 5-hydroxytryptamine receptor 2C | Serotonin receptor | C00001437 | 0 / 0 |
| P17252 | Protein kinase C alpha type | Alpha | C00001437 | 0 / 0 |
| P08173 | Muscarinic acetylcholine receptor M4 | Acetylcholine receptor | C00001437 | 0 / 0 |
| P25103 | Substance-P receptor | Neurokinin receptor | C00001437 | 0 / 0 |
| P25105 | Platelet-activating factor receptor | PAF receptor | C00001437 | 0 / 0 |
| P33032 | Melanocortin receptor 5 | Melanocortin receptor | C00001437 | 0 / 0 |
| P19838 | Nuclear factor NF-kappa-B p105 subunit | Transcription Factor | C00000615 | 0 / 0 |
| P16050 | Arachidonate 15-lipoxygenase | Enzyme | C00000674 | 0 / 0 |
| P29466 | Caspase-1 | C14 | C00001437 | 0 / 0 |
| Q06124 | Tyrosine-protein phosphatase non-receptor type 11 | Tyr | C00000615 | 4 / 2 |
| P05181 | Cytochrome P450 2E1 | Cytochrome P450 2E1 | C00001437 | 0 / 0 |
| P43166 | Carbonic anhydrase 7 | Lyase | C00000615 | 0 / 0 |
| Q15046 | Lysine--tRNA ligase | Enzyme | C00000674 | 2 / 1 |
| P52895 | Aldo-keto reductase family 1 member C2 | Enzyme | C00000615 | 1 / 0 |
| P35218 | Carbonic anhydrase 5A, mitochondrial | Lyase | C00000615 | 0 / 0 |
| Q9Y2D0 | Carbonic anhydrase 5B, mitochondrial | Lyase | C00000615 | 0 / 0 |
| P49146 | Neuropeptide Y receptor type 2 | Neuropeptide Y receptor | C00001437 | 0 / 0 |
| Q16236 | Nuclear factor erythroid 2-related factor 2 | Unclassified protein | C00000674 | 0 / 0 |
| P08908 | 5-hydroxytryptamine receptor 1A | Serotonin receptor | C00005373 | 1 / 0 |
| P10275 | Androgen receptor | NR3C4 | C00000674 | 3 / 4 |
| P23975 | Sodium-dependent noradrenaline transporter | Norepinephrine | C00001437 | 1 / 1 |
| P25100 | Alpha-1D adrenergic receptor | Adrenergic receptor | C00001437 | 0 / 0 |
| P30542 | Adenosine receptor A1 | Adenosine receptor | C00001437 | 0 / 0 |
| P18089 | Alpha-2B adrenergic receptor | Adrenergic receptor | C00001437 | 0 / 0 |
| P24557 | Thromboxane-A synthase | Cytochrome P450 5A1 | C00001437 | 1 / 1 |
| Q9HC97 | G-protein coupled receptor 35 | Kynurenic acid receptor | C00000674 | 0 / 0 |
| Q16539 | Mitogen-activated protein kinase 14 | p38 | C00001437 | 0 / 0 |
| Q04760 | Lactoylglutathione lyase | Enzyme | C00000674 | 0 / 0 |
| P25025 | C-X-C chemokine receptor type 2 | CXC chemokine receptor | C00001437 | 0 / 0 |
| P08254 | Stromelysin-1 | M10A | C00000674 | 1 / 0 |
| P34949 | Mannose-6-phosphate isomerase | Enzyme | C00005373 | 1 / 1 |
| P22748 | Carbonic anhydrase 4 | Lyase | C00000615 | 1 / 1 |
| P33765 | Adenosine receptor A3 | Adenosine receptor | C00001437 | 0 / 0 |
| P08246 | Neutrophil elastase | S1A | C00001437 | 2 / 1 |
| P24298 | Alanine aminotransferase 1 | Enzyme | C00000615 | 0 / 0 |
| P21728 | D(1A) dopamine receptor | Dopamine receptor | C00001437 | 0 / 0 |
| P09917 | Arachidonate 5-lipoxygenase | Oxidoreductase | C00000615 | 0 / 0 |
| P42224 | Signal transducer and activator of transcription 1-alpha/beta | Unclassified protein | C00002770 | 3 / 3 |
| P14618 | Pyruvate kinase PKM | Enzyme | C00002770 | 0 / 0 |
| O60218 | Aldo-keto reductase family 1 member B10 | Enzyme | C00000615 | 0 / 0 |
| Q99700 | Ataxin-2 | Unclassified protein | C00000674 | 1 / 1 |
| P17516 | Aldo-keto reductase family 1 member C4 | Enzyme | C00000615 | 1 / 0 |
| Q07820 | Induced myeloid leukemia cell differentiation protein Mcl-1 | Other cytosolic protein | C00002770 | 0 / 0 |
| P04637 | Cellular tumor antigen p53 | Transcription Factor | C00000674 | 7 / 37 |
| O95067 | G2/mitotic-specific cyclin-B2 | Other cytosolic protein | C00000674 | 0 / 0 |
| P14635 | G2/mitotic-specific cyclin-B1 | Other cytosolic protein | C00000674 | 0 / 0 |
| P06493 | Cyclin-dependent kinase 1 | Cdc2 | C00000674 | 0 / 0 |
| Q8WWL7 | G2/mitotic-specific cyclin-B3 | Other cytosolic protein | C00000674 | 0 / 0 |
| P07900 | Heat shock protein HSP 90-alpha | Other cytosolic protein | C00000615 | 0 / 0 |
| P08238 | Heat shock protein HSP 90-beta | Other cytosolic protein | C00000615 | 0 / 0 |
| P49840 | Glycogen synthase kinase-3 alpha | Gsk | C00000674 | 0 / 0 |
| P49841 | Glycogen synthase kinase-3 beta | Gsk | C00000674 | 0 / 0 |
| P18031 | Tyrosine-protein phosphatase non-receptor type 1 | Tyr | C00000615 | 0 / 0 |
| Q9H0H5 | Rac GTPase-activating protein 1 | Unclassified protein | C00002770 | 0 / 0 |
| Q14191 | Werner syndrome ATP-dependent helicase | Enzyme | C00000674 | 2 / 1 |
76 Gene in CTD interactions
| gene | gene name | gene description | KNApSAcK metabolite in interactions |
|---|---|---|---|
| 4363 | ABCC1, ABC29, ABCC, GS-X, MRP, MRP1 | ATP-binding cassette, sub-family C (CFTR/MRP), member 1 |
C00000674
|
| 9429 | ABCG2, ABC15, ABCP, BCRP, BCRP1, BMDP, CD338, CDw338, EST157481, GOUT1, MRX, MXR, MXR1, UAQTL1 | ATP-binding cassette, sub-family G (WHITE), member 2 |
C00000674
|
| 177 | AGER, RAGE | advanced glycosylation end product-specific receptor |
C00000674
|
| 196 | AHR, bHLHe76 | aryl hydrocarbon receptor |
C00000674
|
| 207 | AKT1, AKT, CWS6, PKB, PKB-ALPHA, PRKBA, RAC, RAC-ALPHA | v-akt murine thymoma viral oncogene homolog 1 (EC:2.7.11.1) |
C00000674
|
| 581 | BAX, BCL2L4 | BCL2-associated X protein |
C00000674
|
| 596 | BCL2, Bcl-2, PPP1R50 | B-cell CLL/lymphoma 2 |
C00000674
|
| 598 | BCL2L1, BCL-XL/S, BCL2L, BCLX, BCLXL, BCLXS, Bcl-X, PPP1R52, bcl-xL, bcl-xS | BCL2-like 1 |
C00000674
|
| 329 | BIRC2, API1, HIAP2, Hiap-2, MIHB, RNF48, c-IAP1, cIAP1 | baculoviral IAP repeat containing 2 |
C00000674
|
| 836 | CASP3, CPP32, CPP32B, SCA-1 | caspase 3, apoptosis-related cysteine peptidase (EC:3.4.22.56) |
C00000674
|
| 840 | CASP7, CASP-7, CMH-1, ICE-LAP3, LICE2, MCH3 | caspase 7, apoptosis-related cysteine peptidase (EC:3.4.22.60) |
C00000674
|
| 841 | CASP8, ALPS2B, CAP4, Casp-8, FLICE, MACH, MCH5 | caspase 8, apoptosis-related cysteine peptidase (EC:3.4.22.61) |
C00000674
|
| 842 | CASP9, APAF-3, APAF3, ICE-LAP6, MCH6, PPP1R56 | caspase 9, apoptosis-related cysteine peptidase (EC:3.4.22.62) |
C00000674
|
| 847 | CAT | catalase (EC:1.11.1.6) |
C00000674
|
| 890 | CCNA2, CCN1, CCNA | cyclin A2 |
C00000674
|
| 891 | CCNB1, CCNB | cyclin B1 |
C00000674
|
| 958 | CD40, Bp50, CDW40, TNFRSF5, p50 | CD40 molecule, TNF receptor superfamily member 5 |
C00000674
|
| 972 | CD74, DHLAG, HLADG, II, Ia-GAMMA | CD74 molecule, major histocompatibility complex, class II invariant chain |
C00000674
|
| 983 | CDK1, CDC2, CDC28A, P34CDC2 | cyclin-dependent kinase 1 (EC:2.7.11.23 2.7.11.22) |
C00000674
|
| 1017 | CDK2, p33(CDK2) | cyclin-dependent kinase 2 (EC:2.7.11.22) |
C00000674
|
| 1026 | CDKN1A, CAP20, CDKN1, CIP1, MDA-6, P21, SDI1, WAF1, p21CIP1 | cyclin-dependent kinase inhibitor 1A (p21, Cip1) |
C00000674
|
| 1027 | CDKN1B, CDKN4, KIP1, MEN1B, MEN4, P27KIP1 | cyclin-dependent kinase inhibitor 1B (p27, Kip1) |
C00000674
|
| 1031 | CDKN2C, INK4C, p18, p18-INK4C | cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4) |
C00000674
|
| 1437 | CSF2, GMCSF | colony stimulating factor 2 (granulocyte-macrophage) |
C00000674
|
| 1543 | CYP1A1, AHH, AHRR, CP11, CYP1, P1-450, P450-C, P450DX | cytochrome P450, family 1, subfamily A, polypeptide 1 (EC:1.14.14.1) |
C00000674
|
| 1545 | CYP1B1, CP1B, CYPIB1, GLC3A, P4501B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 (EC:1.14.14.1) |
C00000674
|
| 1576 | CYP3A4, CP33, CP34, CYP3A, CYP3A3, CYPIIIA3, CYPIIIA4, HLP, NF-25, P450C3, P450PCN1 | cytochrome P450, family 3, subfamily A, polypeptide 4 (EC:1.14.13.67 1.14.13.97 1.14.13.32 1.14.13.157) |
C00000674
|
| 1577 | CYP3A5, CP35, CYPIIIA5, P450PCN3, PCN3 | cytochrome P450, family 3, subfamily A, polypeptide 5 (EC:1.14.14.1) |
C00000674
|
| 1950 | EGF, HOMG4, URG | epidermal growth factor |
C00000674
|
| 1956 | EGFR, ERBB, ERBB1, HER1, PIG61, mENA | epidermal growth factor receptor (EC:2.7.10.1) |
C00000674
|
| 1958 | EGR1, AT225, G0S30, KROX-24, NGFI-A, TIS8, ZIF-268, ZNF225 | early growth response 1 |
C00000674
|
| 2099 | ESR1, ER, ESR, ESRA, ESTRR, Era, NR3A1 | estrogen receptor 1 |
C00000674
|
| 2100 | ESR2, ER-BETA, ESR-BETA, ESRB, ESTRB, Erb, NR3A2 | estrogen receptor 2 (ER beta) |
C00000674
|
| 2203 | FBP1, FBP | fructose-1,6-bisphosphatase 1 (EC:3.1.3.11) |
C00000674
|
| 2353 | FOS, AP-1, C-FOS, p55 | FBJ murine osteosarcoma viral oncogene homolog |
C00000674
|
| 2354 | FOSB, AP-1, G0S3, GOS3, GOSB | FBJ murine osteosarcoma viral oncogene homolog B |
C00000674
|
| 4616 | GADD45B, GADD45BETA, MYD118 | growth arrest and DNA-damage-inducible, beta |
C00000674
|
| 3383 | ICAM1, BB2, CD54, P3.58 | intercellular adhesion molecule 1 |
C00000674
|
| 3553 | IL1B, IL-1, IL1-BETA, IL1F2 | interleukin 1, beta |
C00000674
|
| 3565 | IL4, BCGF-1, BCGF1, BSF-1, BSF1, IL-4 | interleukin 4 |
C00000674
|
| 3725 | JUN, AP-1, AP1, c-Jun | jun proto-oncogene |
C00000674
|
| 3726 | JUNB, AP-1 | jun B proto-oncogene |
C00000674
|
| 3727 | JUND, AP-1 | jun D proto-oncogene |
C00000674
|
| 5594 | MAPK1, ERK, ERK2, ERT1, MAPK2, P42MAPK, PRKM1, PRKM2, p38, p40, p41, p41mapk | mitogen-activated protein kinase 1 (EC:2.7.11.24) |
C00000674
|
| 5602 | MAPK10, JNK3, JNK3A, PRKM10, SAPK1b, p493F12, p54bSAPK | mitogen-activated protein kinase 10 (EC:2.7.11.24) |
C00000674
|
| 5595 | MAPK3, ERK-1, ERK1, ERT2, HS44KDAP, HUMKER1A, P44ERK1, P44MAPK, PRKM3, p44-ERK1, p44-MAPK | mitogen-activated protein kinase 3 (EC:2.7.11.24) |
C00000674
|
| 5599 | MAPK8, JNK, JNK-46, JNK1, JNK1A2, JNK21B1/2, PRKM8, SAPK1, SAPK1c | mitogen-activated protein kinase 8 (EC:2.7.11.24) |
C00000674
|
| 5601 | MAPK9, JNK-55, JNK2, JNK2A, JNK2ALPHA, JNK2B, JNK2BETA, PRKM9, SAPK, SAPK1a, p54a, p54aSAPK | mitogen-activated protein kinase 9 (EC:2.7.11.24) |
C00000674
|
| 4312 | MMP1, CLG, CLGN | matrix metallopeptidase 1 (interstitial collagenase) (EC:3.4.24.7) |
C00000674
|
| 4318 | MMP9, CLG4B, GELB, MANDP2, MMP-9 | matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase) (EC:3.4.24.35) |
C00000674
|
| 4790 | NFKB1, EBP-1, KBF1, NF-kB1, NF-kappa-B, NF-kappaB, NFKB-p105, NFKB-p50, NFkappaB, p105, p50 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 |
C00000674
|
| 4792 | NFKBIA, IKBA, MAD-3, NFKBI | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha |
C00000674
|
| 4793 | NFKBIB, IKBB, TRIP9 | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta |
C00000674
|
| 9572 | NR1D1, EAR1, THRA1, THRAL, ear-1, hRev | nuclear receptor subfamily 1, group D, member 1 |
C00000674
|
| 5347 | PLK1, PLK, STPK13 | polo-like kinase 1 (EC:2.7.11.21) |
C00000674
|
| 8000 | PSCA, PRO232 | prostate stem cell antigen |
C00000674
|
| 5743 | PTGS2, COX-2, COX2, GRIPGHS, PGG/HS, PGHS-2, PHS-2, hCox-2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) (EC:1.14.99.1) |
C00000674
|
| 5747 | PTK2, FADK, FAK, FAK1, FRNK, PPP1R71, p125FAK, pp125FAK | protein tyrosine kinase 2 (EC:2.7.10.2) |
C00000674
|
| 5970 | RELA, NFKB3, p65 | v-rel avian reticuloendotheliosis viral oncogene homolog A |
C00000674
|
| 6401 | SELE, CD62E, ELAM, ELAM1, ESEL, LECAM2 | selectin E |
C00000674
|
| 2810 | SFN, YWHAS | stratifin |
C00000674
|
| 6647 | SOD1, ALS, ALS1, IPOA, SOD, hSod1, homodimer | superoxide dismutase 1, soluble (EC:1.15.1.1) |
C00000674
|
| 29110 | TBK1, NAK, T2K | TANK-binding kinase 1 (EC:2.7.11.1) |
C00000674
|
| 7124 | TNF, DIF, TNF-alpha, TNFA, TNFSF2 | tumor necrosis factor |
C00000674
|
| 7128 | TNFAIP3, A20, OTUD7C, TNFA1P2 | tumor necrosis factor, alpha-induced protein 3 (EC:3.4.19.12) |
C00000674
|
| 8743 | TNFSF10, APO2L, Apo-2L, CD253, TL2, TRAIL | tumor necrosis factor (ligand) superfamily, member 10 |
C00000674
|
| 9540 | TP53I3, PIG3 | tumor protein p53 inducible protein 3 |
C00000674
|
| 8626 | TP63, AIS, B(p51A), B(p51B), EEC3, KET, LMS, NBP, OFC8, RHS, SHFM4, TP53CP, TP53L, TP73L, p40, p51, p53CP, p63, p73H, p73L | tumor protein p63 |
C00000674
|
| 7161 | TP73, P73 | tumor protein p73 |
C00000674
|
| 54658 | UGT1A1, BILIQTL1, GNT1, HUG-BR1, UDPGT, UDPGT_1-1, UGT1, UGT1A | UDP glucuronosyltransferase 1 family, polypeptide A1 (EC:2.4.1.17) |
C00000674
|
| 54659 | UGT1A3, UDPGT, UDPGT_1-3, UGT-1C, UGT1-03, UGT1.3, UGT1C | UDP glucuronosyltransferase 1 family, polypeptide A3 (EC:2.4.1.17) |
C00000674
|
| 10451 | VAV3 | vav 3 guanine nucleotide exchange factor |
C00000674
|
| 7412 | VCAM1, CD106, INCAM-100 | vascular cell adhesion molecule 1 |
C00000674
|
| 7422 | VEGFA, MVCD1, VEGF, VPF | vascular endothelial growth factor A |
C00000674
|
| 8839 | WISP2, CCN5, CT58, CTGF-L | WNT1 inducible signaling pathway protein 2 |
C00000674
|
| 331 | XIAP, API3, BIRC4, IAP-3, ILP1, MIHA, XLP2, hIAP-3, hIAP3 | X-linked inhibitor of apoptosis |
C00000674
|
Related Diseases
Diseases related to proteins in ChEMBL interactions
OMIM (146)
| OMIM | preferred title | UniProt |
|---|---|---|
| #300438 | 17-beta-hydroxysteroid dehydrogenase x deficiency |
Q99714
|
| #614279 | 46,xy sex reversal 8; srxy8 |
P17516
P52895 |
| #100100 | Abdominal muscles, absence of, with urinary tract abnormality and cryptorchidism |
P20309
|
| #202300 | Adrenocortical carcinoma, hereditary; adcc |
P04637
|
| #103470 | Albinism, ocular, with sensorineural deafness |
P14679
|
| #203100 | Albinism, oculocutaneous, type ia; oca1a |
P14679
|
| #606952 | Albinism, oculocutaneous, type ib; oca1b |
P14679
|
| #103780 | Alcohol dependence |
P08172
P14416 P31645 |
| #614373 | Amyotrophic lateral sclerosis 16, juvenile; als16 |
Q99720
|
| #300068 | Androgen insensitivity syndrome; ais |
P10275
|
| #312300 | Androgen insensitivity, partial; pais |
P10275
|
| #600807 | Asthma, susceptibility to |
Q13093
|
| #209950 | Atypical mycobacteriosis, familial |
P42224
|
| #614740 | Basal cell carcinoma, susceptibility to, 7; bcc7 |
P04637
|
| #614490 | Blood group, junior system; jr |
Q9UNQ0
|
| #210900 | Bloom syndrome; blm |
P54132
|
| #602025 | Body mass index quantitative trait locus 9; bmiq9 |
P41968
|
| #114480 | Breast cancer |
P38398
|
| #604370 | Breast-ovarian cancer, familial, susceptibility to, 1; brovca1 |
P38398
|
| #300615 | Brunner syndrome |
P21397
|
| #614162 | Candidiasis, familial, 7; candf7 |
P42224
|
| #115200 | Cardiomyopathy, dilated, 1a; cmd1a |
P02545
|
| #212112 | Cardiomyopathy, dilated, with hypergonadotropic hypogonadism |
P02545
|
| #118300 | Charcot-marie-tooth disease and deafness |
Q01453
|
| #605588 | Charcot-marie-tooth disease, axonal, type 2b1; cmt2b1 |
P02545
|
| #118220 | Charcot-marie-tooth disease, demyelinating, type 1a; cmt1a |
Q01453
|
| #613641 | Charcot-marie-tooth disease, recessive intermediate b; cmtrib |
Q15046
|
| #114500 | Colorectal cancer; crc |
P18054
P84022 Q14191 |
| #602579 | Congenital disorder of glycosylation, type ib; cdg1b |
P34949
|
| #614466 | Coronary heart disease, susceptibility to, 6; chds6 |
P08254
|
| #162800 | Cyclic neutropenia |
P08246
|
| #613916 | Deafness, autosomal recessive 89; dfnb89 |
Q15046
|
| #612522 | Diabetes mellitus, insulin-dependent, 22; iddm22 |
P51681
|
| #119900 | Digital clubbing, isolated congenital |
P15428
|
| #609535 | Drug metabolism, poor, cyp2c19-related |
P33261
|
| #608902 | Drug metabolism, poor, cyp2d6-related |
P10635
|
| #181350 | Emery-dreifuss muscular dystrophy 2, autosomal dominant; edmd2 |
P02545
|
| #609820 | Erythrocytosis, familial, 3; ecyt3 |
Q9GZT9
|
| #133239 | Esophageal cancer |
P04637
P18054 |
| #615363 | Estrogen resistance; estrr |
P03372
|
| #301500 | Fabry disease |
P06280
|
| #600274 | Frontotemporal dementia; ftd |
P10636
|
| #230200 | Galactokinase deficiency |
P51570
|
| #613659 | Gastric cancer |
P04626
|
| #137215 | Gastric cancer, hereditary diffuse; hdgc |
P04626
|
| #608013 | Gaucher disease, perinatal lethal |
P04062
|
| #230800 | Gaucher disease, type i |
P04062
|
| #230900 | Gaucher disease, type ii |
P04062
|
| #231000 | Gaucher disease, type iii |
P04062
|
| #231005 | Gaucher disease, type iiic |
P04062
|
| #231095 | Ghosal hematodiaphyseal dysplasia; ghdd |
P24557
|
| #137750 | Glaucoma 1, open angle, a; glc1a |
Q16678
|
| #231300 | Glaucoma 3, primary congenital, a; glc3a |
Q16678
|
| #137760 | Glaucoma, primary open angle; poag |
Q16678
|
| #137800 | Glioma susceptibility 1; glm1 |
P04626
|
| #232300 | Glycogen storage disease ii |
P10253
|
| #245590 | Growth hormone insensitivity with immunodeficiency |
P51692
|
| #139393 | Guillain-barre syndrome, familial; gbs |
Q01453
|
| #605130 | Hairy elbows, short stature, facial dysmorphism, and developmental delay |
Q03164
|
| #610140 | Heart-hand syndrome, slovenian type |
P02545
|
| #609423 | Human immunodeficiency virus type 1, susceptibility to |
P41597
P51681 |
| #176670 | Hutchinson-gilford progeria syndrome; hgps |
P02545
|
| #147060 | Hyper-ige recurrent infection syndrome, autosomal dominant |
P40763
|
| #143860 | Hyperchlorhidrosis, isolated |
O43570
|
| #145000 | Hyperparathyroidism 1; hrpt1 |
O00255
|
| #603373 | Hyperthyroidism, familial gestational |
P16473
|
| #609152 | Hyperthyroidism, nonautoimmune |
P16473
|
| #145900 | Hypertrophic neuropathy of dejerine-sottas |
Q01453
|
| #259100 | Hypertrophic osteoarthropathy, primary, autosomal recessive, 1; phoar1 |
P15428
|
| #146300 | Hypophosphatasia, adult |
P05186
|
| #241510 | Hypophosphatasia, childhood |
P05186
|
| #241500 | Hypophosphatasia, infantile |
P05186
|
| #275200 | Hypothyroidism, congenital, nongoitrous, 1; chng1 |
P16473
|
| #147050 | Ige responsiveness, atopic; iger |
Q13093
|
| #612244 | Inflammatory bowel disease 13; ibd13 |
P08183
|
| #603932 | Intervertebral disc disease; idd |
P14780
|
| #607785 | Juvenile myelomonocytic leukemia; jmml |
Q06124
|
| #151100 | Leopard syndrome 1 |
Q06124
|
| #601626 | Leukemia, acute myeloid; aml |
P36888
|
| #151623 | Li-fraumeni syndrome 1; lfs1 |
P04637
|
| #151660 | Lipodystrophy, familial partial, type 2; fpld2 |
P02545
|
| #613795 | Loeys-dietz syndrome, type 3; lds3 |
P84022
|
| #613688 | Long qt syndrome 2; lqt2 |
Q12809
|
| #211980 | Lung cancer |
P00533
P04626 P04637 |
| #608516 | Major depressive disorder; mdd |
P08172
|
| #248370 | Mandibuloacral dysplasia with type a lipodystrophy; mada |
P02545
|
| #300705 | Mental retardation, x-linked 17; mrx17 |
Q99714
|
| %300852 | Mental retardation, x-linked 88; mrx88 |
P50052
|
| #300220 | Mental retardation, x-linked, syndromic 10; mrxs10 |
Q99714
|
| #156250 | Metachondromatosis; metcds |
Q06124
|
| #613073 | Metaphyseal anadysplasia 2; mandp2 |
P14780
|
| #601492 | Mucopolysaccharidosis, type ix; mps9 |
Q12794
|
| #259600 | Multicentric osteolysis, nodulosis, and arthropathy; mona |
P08253
|
| #131100 | Multiple endocrine neoplasia, type i; men1 |
O00255
|
| #126200 | Multiple sclerosis, susceptibility to; ms |
P08575
|
| #613205 | Muscular dystrophy, congenital, lmna-related |
P02545
|
| #159001 | Muscular dystrophy, limb-girdle, type 1b; lgmd1b |
P02545
|
| #613796 | Mycobacterial and viral infections, susceptibility to, autosomal recessive |
P42224
|
| #159900 | Myoclonic dystonia |
P14416
|
| #160900 | Myotonic dystrophy 1; dm1 |
Q9NR56
|
| #162500 | Neuropathy, hereditary, with liability to pressure palsies; hnpp |
Q01453
|
| #202700 | Neutropenia, severe congenital, 1, autosomal dominant; scn1 |
P08246
|
| #163950 | Noonan syndrome 1; ns1 |
Q06124
|
| #601665 | Obesity |
P32245
|
| #164230 | Obsessive-compulsive disorder; ocd |
P31645
|
| #613949 | Okt4 epitope deficiency |
P01730
|
| #604715 | Orthostatic intolerance |
P23975
|
| #259730 | Osteopetrosis, autosomal recessive 3; optb3 |
P00918
|
| #167000 | Ovarian cancer |
P04626
P38398 |
| #614320 | Pancreatic cancer, susceptibility to, 4; pnca4 |
P38398
|
| #260500 | Papilloma of choroid plexus; cpp |
P04637
|
| #168600 | Parkinson disease, late-onset; pd |
P04062
|
| #260540 | Parkinson-dementia syndrome |
P10636
|
| #613135 | Parkinsonism-dystonia, infantile; pkdys |
Q01959
|
| #614674 | Periodic fever, menstrual cycle-dependent |
P08908
|
| #604229 | Peters anomaly |
Q16678
|
| #172700 | Pick disease of brain |
P10636
|
| #601399 | Platelet disorder, familial, with associated myeloid malignancy |
Q01196
|
| #614278 | Platelet-activating factor acetylhydrolase deficiency; pafad |
Q13093
|
| #607276 | Resting heart rate, variation in |
P08588
|
| #275210 | Restrictive dermopathy, lethal |
P02545
|
| #600852 | Retinitis pigmentosa 17; rp17 |
P22748
|
| #608971 | Severe combined immunodeficiency, autosomal recessive, t cell-negative, b cell-positive, nk cell-positive |
P08575
|
| #609620 | Short qt syndrome 1; sqt1 |
Q12809
|
| #601800 | Skin/hair/eye pigmentation, variation in, 3; shep3 |
P14679
|
| #313200 | Spinal and bulbar muscular atrophy, x-linked 1; smax1 |
P10275
|
| #253300 | Spinal muscular atrophy, type i; sma1 |
Q16637
|
| #253550 | Spinal muscular atrophy, type ii; sma2 |
Q16637
|
| #253400 | Spinal muscular atrophy, type iii; sma3 |
Q16637
|
| #271150 | Spinal muscular atrophy, type iv; sma4 |
Q16637
|
| #183090 | Spinocerebellar ataxia 2; sca2 |
Q99700
|
| #607250 | Spinocerebellar ataxia, autosomal recessive, with axonal neuropathy; scan1 |
Q9NUW8
|
| #602111 | Spondyloepimetaphyseal dysplasia, missouri type |
P45452
|
| #275355 | Squamous cell carcinoma, head and neck; hnscc |
O14763
P04637 |
| %612223 | Stature quantitative trait locus 11; stqtl11 |
Q00534
|
| #601104 | Supranuclear palsy, progressive, 1; psnp1 |
P10636
|
| #188570 | Thyroid hormone resistance, generalized, autosomal dominant; grth |
P10828
|
| #274300 | Thyroid hormone resistance, generalized, autosomal recessive; grth |
P10828
|
| #145650 | Thyroid hormone resistance, selective pituitary; prth |
P10828
|
| #190300 | Tremor, hereditary essential, 1; etm1 |
P35462
|
| #138900 | Uric acid concentration, serum, quantitative trait locus 1; uaqtl1 |
Q9UNQ0
|
| #277700 | Werner syndrome; wrn |
Q14191
|
| #610379 | West nile virus, susceptibility to |
P51681
|
| #278300 | Xanthinuria, type i |
P47989
|
| #278750 | Xeroderma pigmentosum, variant type; xpv |
Q9Y253
|
| #112100 | Yt blood group antigen |
P22303
|
KEGG DISEASE (121)
| KEGG | name | UniProt |
|---|---|---|
| H00033 | Adrenal carcinoma |
O00255
(related)
P04637 (related) |
| H00034 | Carcinoid |
O00255
(related)
|
| H00045 | Malignant islet cell carcinoma |
O00255
(related)
|
| H00246 | Primary hyperparathyroidism |
O00255
(related)
|
| H01102 | Pituitary adenomas |
O00255
(related)
|
| H01302 | Hyperchlorhidrosis isolated (HCHLH) |
O43570
(related)
|
| H00021 | Renal cell carcinoma |
O43570
(marker)
P04637 (marker) Q16790 (marker) |
| H00016 | Oral cancer |
P00533
(related)
P00533 (marker) P04637 (related) P04637 (marker) P40763 (related) |
| H00017 | Esophageal cancer |
P00533
(related)
P04637 (related) P04637 (marker) P35354 (related) |
| H00018 | Gastric cancer |
P00533
(related)
P04626 (related) P04637 (related) |
| H00022 | Bladder cancer |
P00533
(related)
P04626 (related) P04637 (related) |
| H00028 | Choriocarcinoma |
P00533
(related)
P03956 (related) P04626 (related) P04637 (related) P08253 (related) |
| H00030 | Cervical cancer |
P00533
(related)
P04626 (related) |
| H00042 | Glioma |
P00533
(related)
P00533 (marker) P04637 (related) P04637 (marker) |
| H00055 | Laryngeal cancer |
P00533
(related)
P00533 (marker) P04637 (related) P04637 (marker) |
| H00241 | Combined proximal and distal renal tubular acidosis (RTA type 3) |
P00918
(related)
|
| H00436 | Osteopetrosis |
P00918
(related)
|
| H00264 | Charcot-Marie-Tooth disease (CMT) |
P02545
(related)
Q01453 (related) Q15046 (related) |
| H00294 | Dilated cardiomyopathy (DCM) |
P02545
(related)
|
| H00420 | Familial partial lipodystrophy (FPL) |
P02545
(related)
|
| H00563 | Emery-Dreifuss muscular dystrophy |
P02545
(related)
|
| H00590 | Congenital muscular dystrophies (CMD/MDC) |
P02545
(related)
|
| H00593 | Limb-girdle muscular dystrophy (LGMD) |
P02545
(related)
|
| H00601 | Hutchinson-Gilford progeria syndrome |
P02545
(related)
|
| H00663 | Restrictive dermopathy |
P02545
(related)
|
| H00665 | Mandibuloacral dysplasia |
P02545
(related)
|
| H01216 | Left ventricular noncompaction (LVNC) |
P02545
(related)
|
| H00026 | Endometrial Cancer |
P03372
(marker)
P04626 (related) P04637 (related) Q92731 (marker) |
| H00066 | Lewy body dementia (LBD) |
P04062
(related)
|
| H00126 | Gaucher disease |
P04062
(related)
|
| H00426 | Defects in the degradation of ganglioside |
P04062
(related)
|
| H00810 | Progressive myoclonic epilepsy (PME) |
P04062
(related)
|
| H00599 | 46,XX disorders of sex development (Disorders related to androgen excess) |
P04150
(related)
|
| H00019 | Pancreatic cancer |
P04626
(related)
P04637 (related) P04637 (marker) |
| H00027 | Ovarian cancer |
P04626
(related)
P04637 (related) P38398 (related) |
| H00031 | Breast cancer |
P04626
(related)
P04626 (marker) P04637 (related) P38398 (related) |
| H00046 | Cholangiocarcinoma |
P04626
(related)
P04637 (related) P35354 (related) |
| H00004 | Chronic myeloid leukemia (CML) |
P04637
(related)
Q01196 (related) |
| H00005 | Chronic lymphocytic leukemia (CLL) |
P04637
(related)
P28907 (marker) |
| H00006 | Hairy-cell leukemia |
P04637
(related)
|
| H00008 | Burkitt lymphoma |
P04637
(related)
|
| H00009 | Adult T-cell leukemia |
P04637
(related)
|
| H00010 | Multiple myeloma |
P04637
(related)
|
| H00013 | Small cell lung cancer |
P04637
(related)
|
| H00014 | Non-small cell lung cancer |
P04637
(related)
|
| H00015 | Malignant pleural mesothelioma |
P04637
(related)
|
| H00020 | Colorectal cancer |
P04637
(related)
P04637 (marker) |
| H00025 | Penile cancer |
P04637
(related)
P04637 (marker) P08253 (related) P14780 (related) P35354 (related) |
| H00029 | Vulvar cancer |
P04637
(related)
|
| H00032 | Thyroid cancer |
P04637
(related)
|
| H00036 | Osteosarcoma |
P04637
(related)
P08684 (marker) |
| H00038 | Malignant melanoma |
P04637
(related)
P14679 (marker) |
| H00039 | Basal cell carcinoma |
P04637
(related)
|
| H00040 | Squamous cell carcinoma |
P04637
(related)
|
| H00041 | Kaposi's sarcoma |
P04637
(related)
|
| H00044 | Cancer of the anal canal |
P04637
(related)
|
| H00047 | Gallbladder cancer |
P04637
(related)
|
| H00048 | Hepatocellular carcinoma |
P04637
(related)
|
| H00881 | Li-Fraumeni syndrome |
P04637
(related)
|
| H01007 | Choroid plexus papilloma |
P04637
(related)
|
| H00213 | Hypophosphatasia |
P05186
(related)
|
| H00093 | Combined immunodeficiencies (CIDs) |
P06239
(related)
|
| H00125 | Fabry disease |
P06280
(related)
|
| H00079 | Asthma |
P07550
(related)
|
| H00100 | Neutropenic disorders |
P08246
(related)
|
| H00472 | Torg-Winchester syndrome |
P08253
(related)
|
| H00091 | T-B+Severe combined immunodeficiencies (SCIDs) |
P08575
(related)
|
| H00069 | Glycogen storage diseases (GSD) |
P10253
(related)
|
| H00024 | Prostate cancer |
P10275
(related)
|
| H00062 | Spinal and bulbar muscular atrophy (SBMA) |
P10275
(related)
|
| H00608 | 46,XY disorders of sex development (Disorders in androgen synthesis or action) |
P10275
(related)
|
| H00609 | 46,XY disorders of sex development (Other) |
P10275
(related)
|
| H00058 | Amyotrophic lateral sclerosis (ALS) |
P10636
(related)
|
| H00077 | Progressive supranuclear palsy (PSP) |
P10636
(related)
|
| H00078 | Frontotemporal lobar degeneration (FTLD) |
P10636
(related)
|
| H00023 | Testicular cancer |
P10696
(marker)
|
| H00249 | Thyroid hormone resistance syndrome |
P10828
(related)
|
| H01205 | Coumarin resistance |
P11712
(related)
|
| H00168 | Oculocutaneous albinism (OCA) |
P14679
(related)
|
| H00479 | Metaphyseal dysplasias |
P14780
(related)
P45452 (related) |
| H00457 | Primary hypertrophic osteoarthropathy (PHO) |
P15428
(related)
|
| H01246 | Isolated congenital nail clubbing (ICNC) |
P15428
(related)
|
| H00250 | Congenital nongoitrous hypothyroidism (CHNG) |
P16473
(related)
|
| H01269 | Congenital hyperthyroidism |
P16473
(related)
|
| H00548 | Brunner syndrome |
P21397
(related)
|
| H00527 | Retinitis pigmentosa (RP) |
P22748
(related)
|
| H01031 | Orthostatic intolerance (OI) |
P23975
(related)
|
| H00490 | Diaphyseal dysplasia with anemia (Ghosal) |
P24557
(related)
|
| H01171 | Poor drug metabolism (PM) |
P33261
(related)
|
| H00118 | Congenital disorders of glycosylation (CDG) type I |
P34949
(related)
|
| H00003 | Acute myeloid leukemia (AML) |
P36888
(related)
Q01196 (related) Q01196 (marker) Q13951 (marker) |
| H00107 | Other well-defined immunodeficiency syndromes |
P40763
(related)
|
| H00089 | IFN-gamma/IL-12 axis |
P42224
(related)
|
| H00363 | Candidiasis |
P42224
(related)
|
| H01109 | Chronic mucocutaneous candidiasis (CMC) |
P42224
(related)
|
| H00192 | Xanthinuria |
P47989
(related)
|
| H00480 | Non-syndromic X-linked mental retardation |
P50052
(related)
Q99714 (related) |
| H00070 | Galactosemia |
P51570
(related)
|
| H00931 | Growth hormone insensitivity with immunodeficiency |
P51692
(related)
|
| H00094 | DNA repair defects |
P54132
(related)
|
| H00296 | Defects in RecQ helicases |
P54132
(related)
Q14191 (related) |
| H00001 | Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) |
Q01196
(related)
Q01196 (marker) Q03164 (related) Q03164 (marker) |
| H00978 | Thrombocytopenia (THC) |
Q01196
(related)
|
| H01296 | Hereditary neuropathy with liability to pressure palsies (HNPP) |
Q01453
(related)
|
| H00002 | Acute lymphoblastic leukemia (ALL) (precursor T lymphoblastic leukemia) |
Q03164
(related)
|
| H00523 | Noonan syndrome and related disorders |
Q06124
(related)
|
| H01018 | Metachondromatosis |
Q06124
(related)
|
| H00133 | Mucopolysaccharidosis type IX (MPS9) |
Q12794
(related)
|
| H00421 | Mucopolysaccharidosis (MPS) |
Q12794
(related)
|
| H00720 | Long QT syndrome |
Q12809
(related)
|
| H00725 | Short QT syndrome |
Q12809
(related)
|
| H00455 | Spinal muscular atrophy (SMA) |
Q16637
(related)
|
| H00612 | Primary open angle glaucoma |
Q16678
(related)
|
| H01075 | Peters anomaly |
Q16678
(related)
|
| H01159 | Anterior segment dysgenesis (ASD) |
Q16678
(related)
|
| H01203 | Primary congenital glaucoma (PCG) |
Q16678
(related)
|
| H00063 | Spinocerebellar ataxia (SCA) |
Q99700
(related)
Q9NUW8 (related) |
| H00658 | Syndromic X-linked mental retardation |
Q99714
(related)
|
| H00925 | 2-Methyl-3-hydroxybutyryl-CoA dehydrogenase (MHBD) deficiency |
Q99714
(related)
|
| H00236 | Congenital polycythemia |
Q9GZT9
(related)
|
| H00403 | Disorders of nucleotide excision repair |
Q9Y253
(related)
|