Organism name | Ligustrum obtusifolium |
---|---|
Genus | Ligustrum |
Family | Oleaceae |
Kingdom | Plantae |
Linked NCBI taxonomy name | Ligustrum obtusifolium |
---|---|
Linked NCBI taxonomy ID | 178760 |
Linked level | species |
Family in NCBI taxonomy | Oleaceae |
---|---|
ID | 4144 |
Kingdom (Superkingdom) in NCBI taxonomy | Viridiplantae |
---|---|
ID | 33090 |
Plant class | asterids |
---|---|
ID | 71274 |
KNApSAcK ID | name | ChEMBL link | CTD link |
# of proteins in
ChEMBL interaction / related OMIM / related KEGG DISEASE |
# of genes in
CTD interaction / related diseases |
KCF-S
cluster |
phytochemical
cluster |
figure |
---|---|---|---|---|---|---|---|---|
C00000659
![]() |
Medioresinol
/ (+)-Medioresinol |
CHEMBL376507
CHEMBL513023 |
2 / 1 / 1 | No. 38 | No. 21 |
![]() |
||
C00007190
![]() |
(+)-Pinoresinol
|
CHEMBL267963
CHEMBL487611 CHEMBL460862 |
C103298
|
7 / 5 / 6 | No. 38 | No. 21 |
![]() |
|
C00003093
![]() |
Oleuropein
|
CHEMBL1911053
|
C002769
|
8 / 5 | No. 243 |
![]() |
||
C00010785
![]() |
Ligustroside
|
CHEMBL1086877
|
1 / 1 / 0 | No. 243 |
![]() |
|||
C00000682
![]() |
(-)-Olivil
/ Vladinol C |
CHEMBL517144
|
1 / 1 / 1 | No. 700 | No. 21 |
![]() |
accession | description | class description | KNApSAcK metabolite in interactions |
# of diseases
(OMIM / KEGG) |
---|---|---|---|---|
P10635 | Cytochrome P450 2D6 | Cytochrome P450 2D6 | C00000659 | 1 / 0 |
P09917 | Arachidonate 5-lipoxygenase | Oxidoreductase | C00007190 | 0 / 0 |
P35354 | Prostaglandin G/H synthase 2 | Oxidoreductase | C00007190 | 0 / 3 |
Q03181 | Peroxisome proliferator-activated receptor delta | NR1C2 | C00007190 | 0 / 0 |
P47989 | Xanthine dehydrogenase/oxidase | Oxidoreductase | C00000682 | 1 / 1 |
P37231 | Peroxisome proliferator-activated receptor gamma | NR1C3 | C00007190 | 5 / 3 |
Q96QE3 | ATPase family AAA domain-containing protein 5 | Unclassified protein | C00007190 | 0 / 0 |
P08684 | Cytochrome P450 3A4 | Cytochrome P450 3A4 | C00000659 | 0 / 1 |
P14672 | Solute carrier family 2, facilitated glucose transporter member 4 | Unclassified protein | C00010785 | 1 / 0 |
Q07869 | Peroxisome proliferator-activated receptor alpha | NR1C1 | C00007190 | 0 / 0 |
Q9H0H5 | Rac GTPase-activating protein 1 | Unclassified protein | C00007190 | 0 / 0 |
gene | gene name | gene description | KNApSAcK metabolite in interactions |
---|---|---|---|
1588 | CYP19A1, ARO, ARO1, CPV1, CYAR, CYP19, CYPXIX, P-450AROM | cytochrome P450, family 19, subfamily A, polypeptide 1 (EC:1.14.14.1) |
C00003093
|
3383 | ICAM1, BB2, CD54, P3.58 | intercellular adhesion molecule 1 |
C00003093
|
4318 | MMP9, CLG4B, GELB, MANDP2, MMP-9 | matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase) (EC:3.4.24.35) |
C00003093
|
5743 | PTGS2, COX-2, COX2, GRIPGHS, PGG/HS, PGHS-2, PHS-2, hCox-2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) (EC:1.14.99.1) |
C00003093
|
5970 | RELA, NFKB3, p65 | v-rel avian reticuloendotheliosis viral oncogene homolog A |
C00003093
|
6401 | SELE, CD62E, ELAM, ELAM1, ESEL, LECAM2 | selectin E |
C00003093
|
7124 | TNF, DIF, TNF-alpha, TNFA, TNFSF2 | tumor necrosis factor |
C00003093
|
7412 | VCAM1, CD106, INCAM-100 | vascular cell adhesion molecule 1 |
C00003093
|
OMIM | preferred title | UniProt |
---|---|---|
%606641 | Body mass index; bmi |
P37231
|
#609338 | Carotid intimal medial thickness 1 |
P37231
|
#125853 | Diabetes mellitus, noninsulin-dependent; niddm |
P14672
|
#608902 | Drug metabolism, poor, cyp2d6-related |
P10635
|
#137800 | Glioma susceptibility 1; glm1 |
P37231
|
#604367 | Lipodystrophy, familial partial, type 3; fpld3 |
P37231
|
#601665 | Obesity |
P37231
|
#278300 | Xanthinuria, type i |
P47989
|
KEGG | name | UniProt |
---|---|---|
H00036 | Osteosarcoma |
P08684
(marker)
|
H00017 | Esophageal cancer |
P35354
(related)
|
H00025 | Penile cancer |
P35354
(related)
|
H00046 | Cholangiocarcinoma |
P35354
(related)
|
H00032 | Thyroid cancer |
P37231
(related)
|
H00409 | Type II diabetes mellitus |
P37231
(related)
|
H00420 | Familial partial lipodystrophy (FPL) |
P37231
(related)
|
H00192 | Xanthinuria |
P47989
(related)
|