Crotalaria assamica

• Index
• Plant Species
• Metabolite list (12)
• Human Protein
  / Gene in interactions
• Related Diseases

Species

KNApSAcK Entry

Organism name	Crotalaria assamica
Genus	Crotalaria
Family	Fabaceae
Kingdom	Plantae

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NCBI taxonomy

Entry

Linked NCBI taxonomy name	Crotalaria assamica
Linked NCBI taxonomy ID	671522
Linked level	species

Family

Family in NCBI taxonomy	Fabaceae
ID	3803

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy	Viridiplantae
ID	33090

Plant class

Plant class	rosids
ID	71275

Metabolite list (12)

KNApSAcK ID	name	ChEMBL link	CTD link	# of proteins in ChEMBL interaction / related OMIM / related KEGG DISEASE	# of genes in CTD interaction / related diseases	KCF-S cluster	phytochemical cluster	figure
C00005382	Quercimeritrin / Quercetin 7-glucoside / Quercetin 7-O-beta-D-glucoside	CHEMBL248726	C089996			No. 2	No. 15
C00019382	2'-Methoxygenistein / 5,7,4'-Trihydroxy-2'-methoxyisoflavone	CHEMBL7348				No. 3	No. 15
C00004624	Morin / 3,5,7,2',4'-Pentahydroxyflavonol / 2-(2,4-Dihydroxyphenyl)-3,5,7-trihydroxy-4H-1-benzopyran-4-one	CHEMBL28626	C008548	59 / 40 / 67	9 / 8	No. 3	No. 15
C00000998	Prunin / Naringenin 7-O-beta-D-glucoside / 5,7,4'-Trihydroxyflavanone 7-O-beta-D-glucopyranoside	CHEMBL469654 CHEMBL526845		1 / 2 / 0		No. 12	No. 14
C00003749	Lupeol / Lupenol / (+)-Lupenol	CHEMBL289191 CHEMBL459702	C010480	3 / 0 / 0	2 / 6	No. 23	No. 51
C00000982	Naringenin / (-)-Naringenin	CHEMBL9352 CHEMBL32571	C005273	57 / 46 / 40	35 / 10	No. 25	No. 14
C00000677	Distylin / Dihydroquercetin / (2R,3R)-Taxifolin	CHEMBL66 CHEMBL9249 CHEMBL337309 CHEMBL1492383	C003377	65 / 41 / 37	29 / 1	No. 42	No. 14
C00003672	Sitosterol / beta-sitosterl / (-)-beta-Sitosterol / Stigmast-5-en-3beta-ol	CHEMBL221542 CHEMBL1398443 CHEMBL1875388		17 / 19 / 12		No. 53	No. 11
C00009383	2'-Hydroxydaidzein / 7,2',4'-Trihydroxyisoflavone	CHEMBL6694				No. 71	No. 15
C00009380	Daidzein / 7,4'-Dihydroxyisoflavone	CHEMBL8145	C004742	60 / 68 / 76	113 / 12	No. 71	No. 15
C00009453	2'-Hydroxygenistein	CHEMBL6665		8 / 6 / 5		No. 71	No. 15
C00019733	Crotafuran D / (6aR,11aR)-5'-Acetyl-3,6a-dihydroxyfurano[2',3':9,10]pterocarpan					No. 1279

Human Protein / Gene in interactions

145 ChEMBL Protein in interactions

accession	description	class description	KNApSAcK metabolite in interactions	# of diseases (OMIM / KEGG)
P11712	Cytochrome P450 2C9	Cytochrome P450 2C9	C00000677 C00000982 C00003672 C00004624 C00009380	0 / 1
P08684	Cytochrome P450 3A4	Cytochrome P450 3A4	C00000677 C00000982 C00003672 C00004624 C00009380	0 / 1
P10635	Cytochrome P450 2D6	Cytochrome P450 2D6	C00000677 C00000982 C00003672 C00009380	1 / 0
Q9UNA4	DNA polymerase iota	Enzyme	C00000677 C00000982 C00004624 C00009453	0 / 0
P27695	DNA-(apurinic or apyrimidinic site) lyase	Enzyme	C00000677 C00004624 C00009380 C00009453	0 / 0
P10636	Microtubule-associated protein tau	Unclassified protein	C00000677 C00004624 C00009380 C00009453	4 / 3
P47989	Xanthine dehydrogenase/oxidase	Oxidoreductase	C00000677 C00000982 C00004624 C00009380	1 / 1
P05177	Cytochrome P450 1A2	Cytochrome P450 1A2	C00000677 C00000982 C00003672 C00009380	0 / 0
P06746	DNA polymerase beta	Enzyme	C00000677 C00003672 C00004624 C00009453	0 / 0
P33261	Cytochrome P450 2C19	Cytochrome P450 2C19	C00000677 C00000982 C00003672 C00009380	1 / 1
P49798	Regulator of G-protein signaling 4	Unclassified protein	C00000677 C00003672 C00004624 C00009380	2 / 0
Q99714	3-hydroxyacyl-CoA dehydrogenase type-2	Enzyme	C00000677 C00000982 C00004624 C00009380	3 / 3
Q9NUW8	Tyrosyl-DNA phosphodiesterase 1	Enzyme	C00000982 C00003672 C00004624 C00009380	1 / 1
Q9UNQ0	ATP-binding cassette sub-family G member 2	ATP binding cassette	C00000982 C00000998 C00004624 C00009380	2 / 0
O00255	Menin	Unclassified protein	C00000677 C00000982 C00004624	2 / 5
Q96KQ7	Histone-lysine N-methyltransferase EHMT2	Enzyme	C00000677 C00004624 C00009380	0 / 0
P41145	Kappa-type opioid receptor	Opioid receptor	C00000677 C00000982 C00009380	0 / 0
P11388	DNA topoisomerase 2-alpha	Isomerase	C00003749 C00004624 C00009380	0 / 0
O94956	Solute carrier organic anion transporter family member 2B1	Unclassified protein	C00000982 C00004624 C00009380	0 / 0
Q92887	Canalicular multispecific organic anion transporter 1	Unclassified protein	C00000677 C00000982 C00004624	1 / 1
Q9Y6L6	Solute carrier organic anion transporter family member 1B1	Electrochemical transporter	C00000982 C00004624 C00009380	1 / 0
B2RXH2	Lysine-specific demethylase 4E	Enzyme	C00000677 C00004624 C00009380	0 / 0
P10253	Lysosomal alpha-glucosidase	Hydrolase	C00000677 C00004624 C00009453	1 / 1
Q9UBT6	DNA polymerase kappa	Enzyme	C00000677 C00004624 C00009453	0 / 0
P15428	15-hydroxyprostaglandin dehydrogenase [NAD(+)]	Enzyme	C00000677 C00004624 C00009380	2 / 2
P54132	Bloom syndrome protein	Enzyme	C00000677 C00004624 C00009380	1 / 2
P03372	Estrogen receptor	NR3A1	C00000982 C00003672 C00009380	1 / 1
O75496	Geminin	Unclassified protein	C00000677 C00000982 C00009380	0 / 0
P08183	Multidrug resistance protein 1	drug	C00000982 C00003672 C00004624	1 / 0
P41143	Delta-type opioid receptor	Opioid receptor	C00000677 C00000982 C00009380	0 / 0
Q92731	Estrogen receptor beta	NR3A2	C00000982 C00004624 C00009380	0 / 1
Q9Y253	DNA polymerase eta	Enzyme	C00000677 C00004624 C00009453	1 / 1
P35372	Mu-type opioid receptor	Opioid receptor	C00000677 C00000982 C00009380	0 / 0
P33527	Multidrug resistance-associated protein 1	drugs	C00000982 C00004624 C00009380	0 / 0
P19838	Nuclear factor NF-kappa-B p105 subunit	Transcription Factor	C00000677 C00004624 C00009380	0 / 0
Q03164	Histone-lysine N-methyltransferase 2A	Enzyme	C00000677 C00000982 C00004624	1 / 2
Q9NPD5	Solute carrier organic anion transporter family member 1B3	Electrochemical transporter	C00000982 C00004624 C00009380	1 / 0
P16050	Arachidonate 15-lipoxygenase	Enzyme	C00000677 C00004624	0 / 0
P37059	Estradiol 17-beta-dehydrogenase 2	Enzyme	C00000982 C00009380	0 / 0
P08047	Transcription factor Sp1	Unclassified protein	C00003672 C00003749	0 / 0
P10275	Androgen receptor	NR3C4	C00000982 C00009380	3 / 4
Q13526	Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1	Enzyme	C00000677 C00004624	0 / 0
Q07869	Peroxisome proliferator-activated receptor alpha	NR1C1	C00000982 C00009380	0 / 0
Q96QE3	ATPase family AAA domain-containing protein 5	Unclassified protein	C00009380 C00009453	0 / 0
Q01453	Peripheral myelin protein 22	Unclassified protein	C00000677 C00009380	5 / 2
Q03181	Peroxisome proliferator-activated receptor delta	NR1C2	C00000982 C00009380	0 / 0
Q04760	Lactoylglutathione lyase	Enzyme	C00000982 C00004624	0 / 0
P33765	Adenosine receptor A3	Adenosine receptor	C00000677 C00004624	0 / 0
P46063	ATP-dependent DNA helicase Q1	Enzyme	C00000677 C00004624	0 / 0
P11387	DNA topoisomerase 1	Isomerase	C00003749 C00009380	0 / 0
P40225	Thrombopoietin	Unclassified protein	C00004624 C00009380	1 / 1
P21728	D(1A) dopamine receptor	Dopamine receptor	C00000677 C00004624	0 / 0
P00352	Retinal dehydrogenase 1	Enzyme	C00004624 C00009380	0 / 0
Q13951	Core-binding factor subunit beta	Unclassified protein	C00000677 C00004624	0 / 1
Q9UIF8	Bromodomain adjacent to zinc finger domain protein 2B	Unclassified protein	C00000677 C00004624	0 / 0
Q16637	Survival motor neuron protein	Unclassified protein	C00000677 C00009380	4 / 1
P39748	Flap endonuclease 1	Enzyme	C00000677 C00004624	0 / 0
P56817	Beta-secretase 1	A1A	C00000677 C00004624	0 / 0
P18054	Arachidonate 12-lipoxygenase, 12S-type	Enzyme	C00000677 C00000982	2 / 0
Q01196	Runt-related transcription factor 1	Unclassified protein	C00000677 C00004624	1 / 4
P04745	Alpha-amylase 1	Enzyme	C00000982 C00009380	0 / 0
P37231	Peroxisome proliferator-activated receptor gamma	NR1C3	C00000982 C00009380	5 / 3
P04637	Cellular tumor antigen p53	Transcription Factor	C00004624 C00009380	7 / 37
P18031	Tyrosine-protein phosphatase non-receptor type 1	Tyr	C00000982 C00003672	0 / 0
P11511	Cytochrome P450 19A1	Cytochrome P450 19A1	C00000982 C00009380	2 / 2
P04150	Glucocorticoid receptor	NR3C1	C00000982 C00009380	0 / 1
O94782	Ubiquitin carboxyl-terminal hydrolase 1	Enzyme	C00000982 C00004624	0 / 0
P11021	78 kDa glucose-regulated protein	Unclassified protein	C00000677 C00009380	0 / 0
P22310	UDP-glucuronosyltransferase 1-4	Enzyme	C00000982 C00009380	3 / 0
P14061	Estradiol 17-beta-dehydrogenase 1	Enzyme	C00000982 C00009380	0 / 0
P83916	Chromobox protein homolog 1	Unclassified protein	C00000677 C00004624	0 / 0
P36888	Receptor-type tyrosine-protein kinase FLT3	Pdgfr	C00000677 C00000982	1 / 1
Q15046	Lysine--tRNA ligase	Enzyme	C00004624	2 / 1
Q14790	Caspase-8	C14	C00004624	2 / 1
P00734	Prothrombin	S1A	C00003672	4 / 2
P49841	Glycogen synthase kinase-3 beta	Gsk	C00003672	0 / 0
P15121	Aldose reductase	Enzyme	C00000982	0 / 0
P14679	Tyrosinase	Oxidoreductase	C00003672	4 / 2
P54855	UDP-glucuronosyltransferase 2B15	Enzyme	C00000982	0 / 0
Q16678	Cytochrome P450 1B1	Cytochrome P450 1B1	C00000982	4 / 4
P51151	Ras-related protein Rab-9A	Unclassified protein	C00009380	0 / 0
P45452	Collagenase 3	M10A	C00000677	1 / 1
P16152	Carbonyl reductase [NADPH] 1	Enzyme	C00000982	0 / 0
P28482	Mitogen-activated protein kinase 1	Erk	C00000677	0 / 0
Q92830	Histone acetyltransferase KAT2A	Enzyme	C00004624	0 / 0
Q16665	Hypoxia-inducible factor 1-alpha	Transcription Factor	C00000677	0 / 0
P08253	72 kDa type IV collagenase	M10A	C00000677	1 / 3
P04278	Sex hormone-binding globulin	Secreted protein	C00000982	0 / 0
P00533	Epidermal growth factor receptor	TK tyrosine-protein kinase EGFR subfamily	C00009380	1 / 8
Q9NR56	Muscleblind-like protein 1	Unclassified protein	C00004624	1 / 0
Q9HC97	G-protein coupled receptor 35	Kynurenic acid receptor	C00004624	0 / 0
O15118	Niemann-Pick C1 protein	Unclassified protein	C00009380	1 / 1
O75828	Carbonyl reductase [NADPH] 3	Enzyme	C00000982	0 / 0
P51449	Nuclear receptor ROR-gamma	Nuclear hormone receptor subfamily 1 group F member 3	C00009380	0 / 0
P24864	G1/S-specific cyclin-E1	Other cytosolic protein	C00000982	0 / 2
Q9HAW9	UDP-glucuronosyltransferase 1-8	Enzyme	C00000982	0 / 0
O76074	cGMP-specific 3',5'-cyclic phosphodiesterase	PDE_5A	C00000982	0 / 0
P24941	Cyclin-dependent kinase 2	Cdc2	C00000982	0 / 0
P22303	Acetylcholinesterase	Hydrolase	C00000982	1 / 0
P04798	Cytochrome P450 1A1	Cytochrome P450 1A1	C00000982	0 / 0
P53350	Serine/threonine-protein kinase PLK1	PLK serine/threonine protein kinase subfamily	C00004624	0 / 0
P11309	Serine/threonine-protein kinase pim-1	Pim	C00004624	0 / 0
P05091	Aldehyde dehydrogenase, mitochondrial	Oxidoreductase	C00009380	1 / 1
P55210	Caspase-7	C14	C00004624	0 / 0
P10828	Thyroid hormone receptor beta	NR1A2	C00009380	3 / 1
P16473	Thyrotropin receptor	Glycohormone receptor	C00003672	3 / 2
Q96S37	Solute carrier family 22 member 12	Transporter	C00004624	1 / 1
P02545	Prelamin-A/C	Unclassified protein	C00009380	11 / 10
P03956	Interstitial collagenase	M10A	C00000677	0 / 1
O75604	Ubiquitin carboxyl-terminal hydrolase 2	Enzyme	C00004624	0 / 0
P22309	UDP-glucuronosyltransferase 1-1	Enzyme	C00000982	5 / 1
P62158	Calmodulin	Unclassified protein	C00000982	1 / 0
Q99549	M-phase phosphoprotein 8	Unclassified protein	C00004624	0 / 0
Q16236	Nuclear factor erythroid 2-related factor 2	Unclassified protein	C00009380	0 / 0
P28907	ADP-ribosyl cyclase 1	Enzyme	C00000677	0 / 1
P14780	Matrix metalloproteinase-9	M10A	C00000677	2 / 2
P39900	Macrophage metalloelastase	M10A	C00000677	0 / 0
P35869	Aryl hydrocarbon receptor	Transcription Factor	C00009380	0 / 0
P08254	Stromelysin-1	M10A	C00000677	1 / 0
P49888	Estrogen sulfotransferase	Enzyme	C00000982	0 / 0
P80365	Corticosteroid 11-beta-dehydrogenase isozyme 2	Enzyme	C00003672	1 / 1
P29466	Caspase-1	C14	C00004624	0 / 0
P24298	Alanine aminotransferase 1	Enzyme	C00000677	0 / 0
P04062	Glucosylceramidase	Enzyme	C00000982	6 / 4
Q12809	Potassium voltage-gated channel subfamily H member 2	KCNH, Kv10-12.x (Ether-a-go-go)	C00004624	2 / 2
P35354	Prostaglandin G/H synthase 2	Oxidoreductase	C00000982	0 / 3
P09917	Arachidonate 5-lipoxygenase	Oxidoreductase	C00000677	0 / 0
P14618	Pyruvate kinase PKM	Enzyme	C00009380	0 / 0
Q99700	Ataxin-2	Unclassified protein	C00009380	1 / 1
Q9HAW8	UDP-glucuronosyltransferase 1-10	Enzyme	C00000982	0 / 0
Q07820	Induced myeloid leukemia cell differentiation protein Mcl-1	Other cytosolic protein	C00004624	0 / 0
Q05513	Protein kinase C zeta type	Iota	C00000677	0 / 0
Q04759	Protein kinase C theta type	Delta	C00000677	0 / 1
Q02156	Protein kinase C epsilon type	Eta	C00000677	0 / 0
O94806	Serine/threonine-protein kinase D3	Pkd	C00000677	0 / 0
P17252	Protein kinase C alpha type	Alpha	C00000677	0 / 0
Q05655	Protein kinase C delta type	Delta	C00000677	0 / 0
P05129	Protein kinase C gamma type	Alpha	C00000677	1 / 1
P05771	Protein kinase C beta type	Alpha	C00000677	0 / 0
P24723	Protein kinase C eta type	Eta	C00000677	1 / 0
P41743	Protein kinase C iota type	Iota	C00000677	0 / 0
Q15139	Serine/threonine-protein kinase D1	Pkd	C00000677	0 / 0
P27338	Amine oxidase [flavin-containing] B	Oxidoreductase	C00009380	0 / 0
P21397	Amine oxidase [flavin-containing] A	Oxidoreductase	C00009380	1 / 1
Q9H0H5	Rac GTPase-activating protein 1	Unclassified protein	C00009380	0 / 0

153 Gene in CTD interactions

gene	gene name	gene description	KNApSAcK metabolite in interactions
4363	ABCC1, ABC29, ABCC, GS-X, MRP, MRP1	ATP-binding cassette, sub-family C (CFTR/MRP), member 1	C00000677 C00000982 C00004624 C00009380
54576	UGT1A8, UDPGT, UDPGT_1-8, UGT-1H, UGT1-08, UGT1.8, UGT1A8S, UGT1H	UDP glucuronosyltransferase 1 family, polypeptide A8 (EC:2.4.1.17)	C00000982 C00004624 C00009380
54600	UGT1A9, HLUGP4, LUGP4, UDPGT, UDPGT_1-9, UGT-1I, UGT1-09, UGT1-9, UGT1.9, UGT1AI, UGT1I	UDP glucuronosyltransferase 1 family, polypeptide A9 (EC:2.4.1.17)	C00000982 C00004624 C00009380
54658	UGT1A1, BILIQTL1, GNT1, HUG-BR1, UDPGT, UDPGT_1-1, UGT1, UGT1A	UDP glucuronosyltransferase 1 family, polypeptide A1 (EC:2.4.1.17)	C00000982 C00004624 C00009380
54577	UGT1A7, UDPGT, UDPGT_1-7, UGT-1G, UGT1-07, UGT1.7, UGT1G	UDP glucuronosyltransferase 1 family, polypeptide A7 (EC:2.4.1.17)	C00000982 C00004624 C00009380
54575	UGT1A10, UDPGT, UGT-1J, UGT1-10, UGT1.10, UGT1J	UDP glucuronosyltransferase 1 family, polypeptide A10 (EC:2.4.1.17)	C00000982 C00004624 C00009380
1576	CYP3A4, CP33, CP34, CYP3A, CYP3A3, CYPIIIA3, CYPIIIA4, HLP, NF-25, P450C3, P450PCN1	cytochrome P450, family 3, subfamily A, polypeptide 4 (EC:1.14.13.67 1.14.13.97 1.14.13.32 1.14.13.157)	C00000982 C00009380
7157	TP53, BCC7, LFS1, P53, TRP53	tumor protein p53	C00000982 C00009380
6818	SULT1A3, HAST, HAST3, M-PST, ST1A3/ST1A4, ST1A5, STM, TL-PST	sulfotransferase family, cytosolic, 1A, phenol-preferring, member 3 (EC:2.8.2.1)	C00000982 C00009380
6817	SULT1A1, HAST1/HAST2, P-PST, PST, ST1A1, ST1A3, STP, STP1, TSPST1	sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1 (EC:2.8.2.1)	C00000982 C00009380
6513	SLC2A1, DYT17, DYT18, DYT9, EIG12, GLUT, GLUT1, GLUT1DS, HTLVR, PED	solute carrier family 2 (facilitated glucose transporter), member 1	C00000982 C00009380
3576	IL8, CXCL8, GCP-1, GCP1, LECT, LUCT, LYNAP, MDNCF, MONAP, NAF, NAP-1, NAP1	interleukin 8	C00000982 C00009380
2100	ESR2, ER-BETA, ESR-BETA, ESRB, ESTRB, Erb, NR3A2	estrogen receptor 2 (ER beta)	C00000982 C00009380
2099	ESR1, ER, ESR, ESRA, ESTRR, Era, NR3A1	estrogen receptor 1	C00000982 C00009380
6566	SLC16A1, HHF7, MCT, MCT1	solute carrier family 16 (monocarboxylate transporter), member 1	C00000982 C00004624
3458	IFNG, IFG, IFI	interferon, gamma	C00000677 C00004624
3725	JUN, AP-1, AP1, c-Jun	jun proto-oncogene	C00000677 C00009380
1559	CYP2C9, CPC9, CYP2C, CYP2C10, CYPIIC9, P450IIC9	cytochrome P450, family 2, subfamily C, polypeptide 9 (EC:1.14.13.48 1.14.13.49 1.14.13.80)	C00000982 C00009380
1545	CYP1B1, CP1B, CYPIB1, GLC3A, P4501B1	cytochrome P450, family 1, subfamily B, polypeptide 1 (EC:1.14.14.1)	C00000982 C00009380
1543	CYP1A1, AHH, AHRR, CP11, CYP1, P1-450, P450-C, P450DX	cytochrome P450, family 1, subfamily A, polypeptide 1 (EC:1.14.14.1)	C00000982 C00009380
1728	NQO1, DHQU, DIA4, DTD, NMOR1, NMORI, QR1	NAD(P)H dehydrogenase, quinone 1 (EC:1.6.5.2)	C00000677 C00009380
1588	CYP19A1, ARO, ARO1, CPV1, CYAR, CYP19, CYPXIX, P-450AROM	cytochrome P450, family 19, subfamily A, polypeptide 1 (EC:1.14.14.1)	C00000982 C00009380
836	CASP3, CPP32, CPP32B, SCA-1	caspase 3, apoptosis-related cysteine peptidase (EC:3.4.22.56)	C00000982 C00009380
596	BCL2, Bcl-2, PPP1R50	B-cell CLL/lymphoma 2	C00000982 C00009380
249	ALPL, AP-TNAP, APTNAP, HOPS, TNAP, TNSALP	alkaline phosphatase, liver/bone/kidney (EC:3.1.3.1)	C00000982 C00009380
196	AHR, bHLHe76	aryl hydrocarbon receptor	C00000982 C00009380
10057	ABCC5, ABC33, EST277145, MOAT-C, MOATC, MRP5, SMRP, pABC11	ATP-binding cassette, sub-family C (CFTR/MRP), member 5	C00000982 C00009380
10257	ABCC4, EST170205, MOAT-B, MOATB, MRP4	ATP-binding cassette, sub-family C (CFTR/MRP), member 4	C00000982 C00009380
5932	RBBP8, COM1, CTIP, JWDS, RIM, SAE2, SCKL2	retinoblastoma binding protein 8	C00009380
19	ABCA1, ABC-1, ABC1, CERP, HDLDT1, TGD	ATP-binding cassette, sub-family A (ABC1), member 1	C00009380
7507	XPA, XP1, XPAC	xeroderma pigmentosum, complementation group A	C00000677
7498	XDH, XO, XOR	xanthine dehydrogenase (EC:1.17.1.4 1.17.3.2)	C00000677
119	ADD2, ADDB	adducin 2 (beta)	C00009380
7296	TXNRD1, GRIM-12, TR, TR1, TRXR1, TXNR	thioredoxin reductase 1 (EC:1.8.1.9)	C00000677
7187	TRAF3, CAP-1, CAP1, CD40bp, CRAF1, IIAE5, LAP1	TNF receptor-associated factor 3	C00000677
251	ALPPL2, ALPG, ALPPL, GCAP	alkaline phosphatase, placental-like 2 (EC:3.1.3.1)	C00009380
367	AR, AIS, DHTR, HUMARA, HYSP1, KD, NR3C4, SBMA, SMAX1, TFM	androgen receptor	C00009380
396	ARHGDIA, GDIA1, NPHS8, RHOGDI, RHOGDI-1	Rho GDP dissociation inhibitor (GDI) alpha	C00009380
23545	ATP6V0A2, A2, ARCL, ARCL2A, ATP6A2, ATP6N1D, J6B7, RTF, STV1, TJ6, TJ6M, TJ6S, VPH1, WSS	ATPase, H+ transporting, lysosomal V0 subunit a2 (EC:3.6.3.6)	C00009380
11177	BAZ1A, ACF1, WALp1, WCRF180, hACF1	bromodomain adjacent to zinc finger domain, 1A	C00009380
6772	STAT1, CANDF7, ISGF-3, STAT91	signal transducer and activator of transcription 1, 91kDa	C00000677
598	BCL2L1, BCL-XL/S, BCL2L, BCLX, BCLXL, BCLXS, Bcl-X, PPP1R52, bcl-xL, bcl-xS	BCL2-like 1	C00009380
632	BGLAP, BGP, OC, OCN	bone gamma-carboxyglutamate (gla) protein	C00009380
672	BRCA1, BRCAI, BRCC1, BROVCA1, IRIS, PNCA4, PPP1R53, PSCP, RNF53	breast cancer 1, early onset	C00009380
103993			C00009380
5921	RASA1, CM-AVM, CMAVM, GAP, PKWS, RASA, RASGAP, p120GAP, p120RASGAP	RAS p21 protein activator (GTPase activating protein) 1	C00000677
890	CCNA2, CCN1, CCNA	cyclin A2	C00009380
595	CCND1, BCL1, D11S287E, PRAD1, U21B31	cyclin D1	C00009380
1017	CDK2, p33(CDK2)	cyclin-dependent kinase 2 (EC:2.7.11.22)	C00009380
1019	CDK4, CMM3, PSK-J3	cyclin-dependent kinase 4 (EC:2.7.11.22)	C00009380
1026	CDKN1A, CAP20, CDKN1, CIP1, MDA-6, P21, SDI1, WAF1, p21CIP1	cyclin-dependent kinase inhibitor 1A (p21, Cip1)	C00009380
1103	CHAT, CHOACTASE, CMS1A, CMS1A2	choline O-acetyltransferase (EC:2.3.1.6)	C00009380
1152	CKB, B-CK, CKBB	creatine kinase, brain (EC:2.7.3.2)	C00009380
1312	COMT	catechol-O-methyltransferase (EC:2.1.1.6)	C00009380
9167	COX7A2L, COX7AR, COX7RP, EB1, SIG81	cytochrome c oxidase subunit VIIa polypeptide 2 like	C00009380
1374	CPT1A, CPT1, CPT1-L, L-CPT1	carnitine palmitoyltransferase 1A (liver) (EC:2.3.1.21)	C00009380
1401	CRP, PTX1	C-reactive protein, pentraxin-related	C00009380
6387	CXCL12, IRH, PBSF, SCYB12, SDF1, TLSF, TPAR1, SDF1A, SDF1B	chemokine (C-X-C motif) ligand 12	C00009380
5155	PDGFB, IBGC5, PDGF-2, PDGF2, SIS, SSV, c-sis	platelet-derived growth factor beta polypeptide	C00000677
4780	NFE2L2, NRF2	nuclear factor, erythroid 2-like 2	C00000677
4547	MTTP, ABL, MTP	microsomal triglyceride transfer protein	C00000677
1589	CYP21A2, CA21H, CAH1, CPS1, CYP21, CYP21B, P450c21B	cytochrome P450, family 21, subfamily A, polypeptide 2 (EC:1.14.99.10)	C00009380
5599	MAPK8, JNK, JNK-46, JNK1, JNK1A2, JNK21B1/2, PRKM8, SAPK1, SAPK1c	mitogen-activated protein kinase 8 (EC:2.7.11.24)	C00000677
1565	CYP2D6, CPD6, CYP2D, CYP2D7AP, CYP2D7BP, CYP2D7P2, CYP2D8P2, CYP2DL1, CYPIID6, P450-DB1, P450C2D, P450DB1	cytochrome P450, family 2, subfamily D, polypeptide 6 (EC:1.14.14.1)	C00009380
3383	ICAM1, BB2, CD54, P3.58	intercellular adhesion molecule 1	C00000677
1795	DOCK3, MOCA, PBP	dedicator of cytokinesis 3	C00009380
1846	DUSP4, HVH2, MKP-2, MKP2, TYP	dual specificity phosphatase 4 (EC:3.1.3.16 3.1.3.48)	C00009380
9166	EBAG9, EB9, PDAF	estrogen receptor binding site associated, antigen, 9	C00009380
1956	EGFR, ERBB, ERBB1, HER1, PIG61, mENA	epidermal growth factor receptor (EC:2.7.10.1)	C00009380
2027	ENO3, GSD13, MSE	enolase 3 (beta, muscle) (EC:4.2.1.11)	C00009380
2041	EPHA1, EPH, EPHT, EPHT1	EPH receptor A1 (EC:2.7.10.1)	C00009380
83715	ESPN, DFNB36	espin	C00009380
3162	HMOX1, HMOX1D, HO-1, HSP32, bK286B10	heme oxygenase (decycling) 1 (EC:1.14.99.3)	C00000677
2944	GSTM1, GST1, GSTM1-1, GSTM1a-1a, GSTM1b-1b, GTH4, GTM1, H-B, MU, MU-1	glutathione S-transferase mu 1 (EC:2.5.1.18)	C00000677
2101	ESRRA, ERR1, ERRa, ERRalpha, ESRL1, NR3B1	estrogen-related receptor alpha	C00009380
2103	ESRRB, DFNB35, ERR2, ERRb, ESRL2, NR3B2	estrogen-related receptor beta	C00009380
2104	ESRRG, ERR3, ERRgamma, NR3B3	estrogen-related receptor gamma	C00009380
56776	FMN2	formin 2	C00009380
2353	FOS, AP-1, C-FOS, p55	FBJ murine osteosarcoma viral oncogene homolog	C00009380
9687	GREB1	growth regulation by estrogen in breast cancer 1	C00009380
3284	HSD3B2, HSD3B, HSDB, SDR11E2	hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2 (EC:1.1.1.145 5.3.3.1)	C00009380
7866	IFRD2, IFNRP, SKMc15, SM15	interferon-related developmental regulator 2	C00009380
3480	IGF1R, CD221, IGFIR, IGFR, JTK13	insulin-like growth factor 1 receptor (EC:2.7.10.1)	C00009380
3487	IGFBP4, BP-4, HT29-IGFBP, IBP4, IGFBP-4	insulin-like growth factor binding protein 4	C00009380
3553	IL1B, IL-1, IL1-BETA, IL1F2	interleukin 1, beta	C00009380
3569	IL6, BSF2, HGF, HSF, IFNB2, IL-6	interleukin 6 (interferon, beta 2)	C00009380
9518	GDF15, GDF-15, MIC-1, MIC1, NAG-1, PDF, PLAB, PTGFB	growth differentiation factor 15	C00000677
26145	IRF2BP1	interferon regulatory factor 2 binding protein 1	C00009380
26251	KCNG2, KCNF2, KV6.2	potassium voltage-gated channel, subfamily G, member 2	C00009380
354	KLK3, APS, KLK2A1, PSA, hK3	kallikrein-related peptidase 3 (EC:3.4.21.77)	C00009380
27074	LAMP3, CD208, DC_LAMP, DC-LAMP, DCLAMP, LAMP, LAMP-3, TSC403	lysosomal-associated membrane protein 3	C00009380
5594	MAPK1, ERK, ERK2, ERT1, MAPK2, P42MAPK, PRKM1, PRKM2, p38, p40, p41, p41mapk	mitogen-activated protein kinase 1 (EC:2.7.11.24)	C00009380
5595	MAPK3, ERK-1, ERK1, ERT2, HS44KDAP, HUMKER1A, P44ERK1, P44MAPK, PRKM3, p44-ERK1, p44-MAPK	mitogen-activated protein kinase 3 (EC:2.7.11.24)	C00009380
4199	ME1, HUMNDME, MES	malic enzyme 1, NADP(+)-dependent, cytosolic (EC:1.1.1.40)	C00009380
4502	MT2A, MT2	metallothionein 2A	C00009380
4609	MYC, MRTL, MYCC, bHLHe39, c-Myc	v-myc avian myelocytomatosis viral oncogene homolog	C00009380
10499	NCOA2, GRIP1, KAT13C, NCoA-2, SRC2, TIF2, bHLHe75	nuclear receptor coactivator 2	C00009380
4824	NKX3-1, BAPX2, NKX3, NKX3.1, NKX3A	NK3 homeobox 1	C00009380
4846	NOS3, ECNOS, eNOS	nitric oxide synthase 3 (endothelial cell) (EC:1.14.13.39)	C00009380
8856	NR1I2, BXR, ONR1, PAR, PAR1, PAR2, PARq, PRR, PXR, SAR, SXR	nuclear receptor subfamily 1, group I, member 2	C00009380
8204	NRIP1, RIP140	nuclear receptor interacting protein 1	C00009380
56944	OLFML3, HNOEL-iso, OLF44	olfactomedin-like 3	C00009380
142	PARP1, ADPRT, ADPRT_1, ADPRT1, ARTD1, PARP, PARP-1, PPOL, pADPRT-1	poly (ADP-ribose) polymerase 1 (EC:2.4.2.30)	C00009380
5111	PCNA	proliferating cell nuclear antigen	C00009380
64236	PDLIM2, MYSTIQUE, SLIM	PDZ and LIM domain 2 (mystique)	C00009380
5174	PDZK1, CAP70, CLAMP, NHERF-3, NHERF3, PDZD1	PDZ domain containing 1	C00009380
5241	PGR, NR3C3, PR	progesterone receptor	C00009380
5411	PNN, DRS, DRSP, SDK3, memA	pinin, desmosome associated protein	C00009380
10957	PNRC1, B4-2, PNAS-145, PROL2, PRR2	proline-rich nuclear receptor coactivator 1	C00009380
5458	POU4F2, BRN3.2, BRN3B, Brn-3b	POU class 4 homeobox 2	C00009380
5580	PRKCD, MAY1, PKCD, nPKC-delta	protein kinase C, delta (EC:2.7.10.2 2.7.11.13)	C00009380
11098	PRSS23, SIG13, SPUVE, ZSIG13	protease, serine, 23	C00009380
5743	PTGS2, COX-2, COX2, GRIPGHS, PGG/HS, PGHS-2, PHS-2, hCox-2	prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) (EC:1.14.99.1)	C00009380
5747	PTK2, FADK, FAK, FAK1, FRNK, PPP1R71, p125FAK, pp125FAK	protein tyrosine kinase 2 (EC:2.7.10.2)	C00009380
7518	XRCC4	X-ray repair complementing defective repair in Chinese hamster cells 4	C00000677
6197	RPS6KA3, CLS, HU-3, ISPK-1, MAPKAPK1B, MRX19, RSK, RSK2, S6K-alpha3, p90-RSK2, pp90RSK2	ribosomal protein S6 kinase, 90kDa, polypeptide 3 (EC:2.7.11.1)	C00009380
81537	SGPP1, SPPase1	sphingosine-1-phosphate phosphatase 1	C00009380
6558	SLC12A2, BSC, BSC2, NKCC1	solute carrier family 12 (sodium/potassium/chloride transporter), member 2	C00009380
2621	GAS6, AXLLG, AXSF	growth arrest-specific 6	C00000677
8140	SLC7A5, 4F2LC, CD98, D16S469E, E16, LAT1, MPE16, hLAT1	solute carrier family 7 (amino acid transporter light chain, L system), member 5	C00009380
6781	STC1, STC	stanniocalcin 1	C00009380
27347	STK39, DCHT, PASK, SPAK	serine threonine kinase 39 (EC:2.7.11.1)	C00009380
2248	FGF3, HBGF-3, INT2	fibroblast growth factor 3	C00000677
8817	FGF18, FGF-18, ZFGF5	fibroblast growth factor 18	C00000677
6870	TACR3, HH11, NK-3R, NK3R, NKR, TAC3RL	tachykinin receptor 3	C00009380
7031	TFF1, BCEI, D21S21, HP1.A, HPS2, pNR-2, pS2	trefoil factor 1	C00009380
7041	TGFB1I1, ARA55, HIC-5, HIC5, TSC-5	transforming growth factor beta 1 induced transcript 1	C00009380
7130	TNFAIP6, TSG-6, TSG6	tumor necrosis factor, alpha-induced protein 6	C00009380
1950	EGF, HOMG4, URG	epidermal growth factor	C00000677
9537	TP53I11, PIG11	tumor protein p53 inducible protein 11	C00009380
7164	TPD52L1, D53, hD53	tumor protein D52-like 1	C00009380
7345	UCHL1, NDGOA, PARK5, PGP_9.5, PGP9.5, PGP95, Uch-L1	ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) (EC:3.4.19.12)	C00009380
1630	DCC, CRC18, CRCR1, IGDCC1, MRMV1	deleted in colorectal carcinoma	C00000677
1571	CYP2E1, CPE1, CYP2E, P450-J, P450C2E	cytochrome P450, family 2, subfamily E, polypeptide 1 (EC:1.14.13.n7)	C00000677
993	CDC25A, CDC25A2	cell division cycle 25A (EC:3.1.3.48)	C00000677
8900	CCNA1	cyclin A1	C00000677
338	APOB, FLDB, LDLCQ4	apolipoprotein B	C00000677
7367	UGT2B17, BMND12, UDPGT2B17	UDP glucuronosyltransferase 2 family, polypeptide B17 (EC:2.4.1.17)	C00009380
7412	VCAM1, CD106, INCAM-100	vascular cell adhesion molecule 1	C00009380
1645	AKR1C1, 2-ALPHA-HSD, 20-ALPHA-HSD, C9, DD1, DD1/DD2, DDH, DDH1, H-37, HAKRC, HBAB, MBAB	aldo-keto reductase family 1, member C1 (EC:1.3.1.20 1.1.1.149 1.1.1.112)	C00000982
8644	AKR1C3, DD3, DDX, HA1753, HAKRB, HAKRe, HSD17B5, PGFS, hluPGFS	aldo-keto reductase family 1, member C3 (EC:1.3.1.20 1.1.1.188 1.1.1.239 1.1.1.64 1.1.1.112 1.1.1.357)	C00000982
207	AKT1, AKT, CWS6, PKB, PKB-ALPHA, PRKBA, RAC, RAC-ALPHA	v-akt murine thymoma viral oncogene homolog 1 (EC:2.7.11.1)	C00000982
405	ARNT, HIF-1-beta, HIF-1beta, HIF1-beta, HIF1B, HIF1BETA, TANGO, bHLHe2	aryl hydrocarbon receptor nuclear translocator	C00000982
842	CASP9, APAF-3, APAF3, ICE-LAP6, MCH6, PPP1R56	caspase 9, apoptosis-related cysteine peptidase (EC:3.4.22.62)	C00000982
1544	CYP1A2, CP12, P3-450, P450(PA)	cytochrome P450, family 1, subfamily A, polypeptide 2 (EC:1.14.14.1)	C00000982
3757	KCNH2, ERG1, HERG, HERG1, Kv11.1, LQT2, SQT1	potassium voltage-gated channel, subfamily H (eag-related), member 2	C00000982
5444	PON1, ESA, MVCD5, PON	paraoxonase 1 (EC:3.1.1.2 3.1.8.1 3.1.1.81)	C00000982
335	APOA1	apolipoprotein A-I	C00000677
7124	TNF, DIF, TNF-alpha, TNFA, TNFSF2	tumor necrosis factor	C00000982
7366	UGT2B15, HLUG4, UDPGT_2B8, UDPGT2B15, UDPGTH3, UGT2B8	UDP glucuronosyltransferase 2 family, polypeptide B15 (EC:2.4.1.17)	C00000982
351	APP, AAA, ABETA, ABPP, AD1, APPI, CTFgamma, CVAP, PN-II, PN2	amyloid beta (A4) precursor protein	C00004624
1499	CTNNB1, CTNNB, MRD19, armadillo	catenin (cadherin-associated protein), beta 1, 88kDa	C00003749
5728	PTEN, 10q23del, BZS, CWS1, DEC, GLM2, MHAM, MMAC1, PTEN1, TEP1	phosphatase and tensin homolog (EC:3.1.3.67 3.1.3.16 3.1.3.48)	C00003749

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