| Organism name | Stephania micrantha H.S.Lo | 
|---|---|
| Genus | Stephania | 
| Family | Menispermaceae | 
| Kingdom | Plantae | 
| Linked NCBI taxonomy name | Stephania | 
|---|---|
| Linked NCBI taxonomy ID | 147243 | 
| Linked level | genus | 
| Family in NCBI taxonomy | Menispermaceae | 
|---|---|
| ID | 3455 | 
| Kingdom (Superkingdom) in NCBI taxonomy | Viridiplantae | 
|---|---|
| ID | 33090 | 
| Plant class | eudicotyledons | 
|---|---|
| ID | 71240 | 
| KNApSAcK ID | name | ChEMBL link | CTD link | # of proteins in ChEMBL interaction / related OMIM / related KEGG DISEASE | # of genes in CTD interaction / related diseases | KCF-S cluster | phytochemical cluster | figure | 
|---|---|---|---|---|---|---|---|---|
| C00025604   | Cycleanine / (-)-Cycleanine | CHEMBL1711244 CHEMBL1983719 | C037098 | 7 / 1 / 1 | No. 10 | No. 4 |   | |
| C00025602   | l-Curine / (-)-Curine / l-Bebeerine / Aristolochine / (-)-Bebeerine / Aristolochine(C36 alkaloid) | CHEMBL1169627 | 13 / 6 / 5 | No. 10 | No. 4 |   | ||
| C00025655   | Corytuberine / (+)-Corytuberine | CHEMBL227965 | C013896 | 1 / 0 / 0 | No. 20 | No. 4 |   | |
| C00025827   | Corydine / Glaucentrin / (+)-Corydine / Glaucentrine | CHEMBL489524 CHEMBL2002847 | C067341 | 1 / 0 / 0 | No. 20 | No. 4 |   | |
| C00025241   | Kikemanin / Kikemanine / Corydalmine / Schefferine / (-)-Kikemanine / (-)-Corydalmine | CHEMBL448891 CHEMBL1209608 CHEMBL2334894 | C058198 | 5 / 3 / 0 | No. 37 | No. 4 |   | |
| C00025252   | Rotundine / l-Tetrahydropalmatine / (-)-Tetrahydropalmatine / (-)-Rotundine(Stephania) | CHEMBL187892 CHEMBL487182 CHEMBL2334889 | 8 / 5 / 2 | No. 37 | No. 4 |   | ||
| C00026094   | Stepholidine / (-)-Stepholidine | CHEMBL487387 CHEMBL2334890 | C010513 | 7 / 4 / 0 | 0 / 1 | No. 37 | No. 4 |   | 
| C00026117   | Corypalmine / (-)-Corypalmine | CHEMBL2334885 CHEMBL2334886 | 4 / 3 / 0 | No. 37 | No. 4 |   | ||
| C00025845   | Dehydroroemerine / Dehydroremerine / 6a,7-Didehydroaporheine | CHEMBL1171263 | C030170 | No. 416 |   | |||
| C00025843   | Dehydroisolaureline | No. 416 |   | |||||
| C00025846   | Dehydrostephanine / 1,2-Methylenedioxy-8-methoxydehydroaporphine | C030171 | No. 416 |   | 
| accession | description | class description | KNApSAcK metabolite in interactions | # of diseases (OMIM / KEGG) | 
|---|---|---|---|---|
| P28223 | 5-hydroxytryptamine receptor 2A | Serotonin receptor | C00025241 C00025252 C00026094 C00026117 | 0 / 0 | 
| P14416 | D(2) dopamine receptor | Dopamine receptor | C00025241 C00025252 C00026094 C00026117 | 2 / 0 | 
| P08908 | 5-hydroxytryptamine receptor 1A | Serotonin receptor | C00025241 C00025252 C00026094 C00026117 | 1 / 0 | 
| P21728 | D(1A) dopamine receptor | Dopamine receptor | C00025241 C00025252 C00026094 C00026117 | 0 / 0 | 
| P13726 | Tissue factor | Membrane receptor | C00025241 C00025252 C00026094 | 0 / 0 | 
| O75164 | Lysine-specific demethylase 4A | Enzyme | C00025602 C00025604 | 0 / 0 | 
| P24941 | Cyclin-dependent kinase 2 | Cdc2 | C00025655 C00025827 | 0 / 0 | 
| Q99700 | Ataxin-2 | Unclassified protein | C00025602 C00025604 | 1 / 1 | 
| O75496 | Geminin | Unclassified protein | C00025602 C00025604 | 0 / 0 | 
| Q9UIF8 | Bromodomain adjacent to zinc finger domain protein 2B | Unclassified protein | C00025602 | 0 / 0 | 
| P21917 | D(4) dopamine receptor | Dopamine receptor | C00026094 | 0 / 0 | 
| P41143 | Delta-type opioid receptor | Opioid receptor | C00025602 | 0 / 0 | 
| Q99720 | Sigma non-opioid intracellular receptor 1 | Membrane receptor | C00025252 | 1 / 0 | 
| P43220 | Glucagon-like peptide 1 receptor | Glucagon-like peptide receptor | C00025604 | 0 / 0 | 
| P42858 | Huntingtin | Unclassified protein | C00025602 | 1 / 1 | 
| P03372 | Estrogen receptor | NR3A1 | C00025252 | 1 / 1 | 
| P47898 | 5-hydroxytryptamine receptor 5A | Serotonin receptor | C00025602 | 0 / 0 | 
| P35372 | Mu-type opioid receptor | Opioid receptor | C00025602 | 0 / 0 | 
| P08684 | Cytochrome P450 3A4 | Cytochrome P450 3A4 | C00025252 | 0 / 1 | 
| Q9UNA4 | DNA polymerase iota | Enzyme | C00025604 | 0 / 0 | 
| P21918 | D(1B) dopamine receptor | Dopamine receptor | C00026094 | 1 / 0 | 
| P10636 | Microtubule-associated protein tau | Unclassified protein | C00025602 | 4 / 3 | 
| Q13526 | Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 | Enzyme | C00025604 | 0 / 0 | 
| O43603 | Galanin receptor type 2 | Galanin receptor | C00025602 | 0 / 0 | 
| Q9UBT6 | DNA polymerase kappa | Enzyme | C00025602 | 0 / 0 | 
| Q96KQ7 | Histone-lysine N-methyltransferase EHMT2 | Enzyme | C00025602 | 0 / 0 | 
| Q8IUX4 | DNA dC->dU-editing enzyme APOBEC-3F | Enzyme | C00025604 | 0 / 0 | 
| P43351 | DNA repair protein RAD52 homolog | Unclassified protein | C00025602 | 0 / 0 | 
| OMIM | preferred title | UniProt | 
|---|---|---|
| #103780 | Alcohol dependence | P14416 | 
| #614373 | Amyotrophic lateral sclerosis 16, juvenile; als16 | Q99720 | 
| #606798 | Blepharospasm, benign essential | P21918 | 
| #615363 | Estrogen resistance; estrr | P03372 | 
| #600274 | Frontotemporal dementia; ftd | P10636 | 
| #143100 | Huntington disease; hd | P42858 | 
| #159900 | Myoclonic dystonia | P14416 | 
| #260540 | Parkinson-dementia syndrome | P10636 | 
| #614674 | Periodic fever, menstrual cycle-dependent | P08908 | 
| #172700 | Pick disease of brain | P10636 | 
| #183090 | Spinocerebellar ataxia 2; sca2 | Q99700 | 
| #601104 | Supranuclear palsy, progressive, 1; psnp1 | P10636 | 
| KEGG | name | UniProt | 
|---|---|---|
| H00026 | Endometrial Cancer | P03372
                            (marker) | 
| H00036 | Osteosarcoma | P08684
                            (marker) | 
| H00058 | Amyotrophic lateral sclerosis (ALS) | P10636
                            (related) | 
| H00077 | Progressive supranuclear palsy (PSP) | P10636
                            (related) | 
| H00078 | Frontotemporal lobar degeneration (FTLD) | P10636
                            (related) | 
| H00059 | Huntington's disease (HD) | P42858
                            (related) | 
| H00063 | Spinocerebellar ataxia (SCA) | Q99700
                            (related) |