| Organism name | Stephania zippeliana Miq. | 
|---|---|
| Genus | Stephania | 
| Family | Menispermaceae | 
| Kingdom | Plantae | 
| Linked NCBI taxonomy name | Stephania | 
|---|---|
| Linked NCBI taxonomy ID | 147243 | 
| Linked level | genus | 
| Family in NCBI taxonomy | Menispermaceae | 
|---|---|
| ID | 3455 | 
| Kingdom (Superkingdom) in NCBI taxonomy | Viridiplantae | 
|---|---|
| ID | 33090 | 
| Plant class | eudicotyledons | 
|---|---|
| ID | 71240 | 
| KNApSAcK ID | name | ChEMBL link | CTD link | # of proteins in ChEMBL interaction / related OMIM / related KEGG DISEASE | # of genes in CTD interaction / related diseases | KCF-S cluster | phytochemical cluster | figure | 
|---|---|---|---|---|---|---|---|---|
| C00025827   | Corydine / Glaucentrin / (+)-Corydine / Glaucentrine | CHEMBL489524 CHEMBL2002847 | C067341 | 1 / 0 / 0 | No. 20 | No. 4 |   | |
| C00025658   | / Eximine / Dicentrine / d-Dicentrine / (+)-Dicentrine / O,N-Dimethyllitseferine | CHEMBL464748 CHEMBL478754 | C067342 | 15 / 20 / 16 | No. 20 | No. 4 |   | |
| C00025659   | Epiglaufidine / (+)-Epiglaufidine | No. 20 | No. 4 |   | ||||
| C00025339   | Oxocrebanine / 8,9-Dimethoxyliriodenine | No. 74 |   | |||||
| C00025849   | Dicentrinone / Oxodicentrine | CHEMBL463284 | 1 / 0 / 0 | No. 74 |   | |||
| C00025687   | Stephodeline / (+)-Stephodeline | No. 346 | No. 4 |   | ||||
| C00025691   | Zippelianine / (+)-Zippelianine / 2-O-Demethyl-(+)-stephodeline | No. 346 | No. 4 |   | ||||
| C00025692   | Zippeline / (+)-Zippeline / 8-Demethoxy-(+)-stephodeline | No. 346 | No. 4 |   | ||||
| C00025661   | Erromangine / (+)-Erromangine / 14-Epi-(+)-isostephodeline | No. 346 | No. 4 |   | ||||
| C00025688   | Tannagine / (+)-Tannagine / 14-Epi-(+)-stephodeline | No. 346 | No. 4 |   | 
| accession | description | class description | KNApSAcK metabolite in interactions | # of diseases (OMIM / KEGG) | 
|---|---|---|---|---|
| P24941 | Cyclin-dependent kinase 2 | Cdc2 | C00025658 C00025827 | 0 / 0 | 
| Q9UNA4 | DNA polymerase iota | Enzyme | C00025658 | 0 / 0 | 
| P06746 | DNA polymerase beta | Enzyme | C00025658 | 0 / 0 | 
| Q9NR56 | Muscleblind-like protein 1 | Unclassified protein | C00025658 | 1 / 0 | 
| P11387 | DNA topoisomerase 1 | Isomerase | C00025849 | 0 / 0 | 
| P39748 | Flap endonuclease 1 | Enzyme | C00025658 | 0 / 0 | 
| O75496 | Geminin | Unclassified protein | C00025658 | 0 / 0 | 
| Q03164 | Histone-lysine N-methyltransferase 2A | Enzyme | C00025658 | 1 / 2 | 
| P02545 | Prelamin-A/C | Unclassified protein | C00025658 | 11 / 10 | 
| O75164 | Lysine-specific demethylase 4A | Enzyme | C00025658 | 0 / 0 | 
| P10636 | Microtubule-associated protein tau | Unclassified protein | C00025658 | 4 / 3 | 
| Q16236 | Nuclear factor erythroid 2-related factor 2 | Unclassified protein | C00025658 | 0 / 0 | 
| B2RXH2 | Lysine-specific demethylase 4E | Enzyme | C00025658 | 0 / 0 | 
| O75874 | Isocitrate dehydrogenase [NADP] cytoplasmic | Enzyme | C00025658 | 1 / 0 | 
| Q14191 | Werner syndrome ATP-dependent helicase | Enzyme | C00025658 | 2 / 1 | 
| P43351 | DNA repair protein RAD52 homolog | Unclassified protein | C00025658 | 0 / 0 | 
| OMIM | preferred title | UniProt | 
|---|---|---|
| #115200 | Cardiomyopathy, dilated, 1a; cmd1a | P02545 | 
| #212112 | Cardiomyopathy, dilated, with hypergonadotropic hypogonadism | P02545 | 
| #605588 | Charcot-marie-tooth disease, axonal, type 2b1; cmt2b1 | P02545 | 
| #114500 | Colorectal cancer; crc | Q14191 | 
| #181350 | Emery-dreifuss muscular dystrophy 2, autosomal dominant; edmd2 | P02545 | 
| #600274 | Frontotemporal dementia; ftd | P10636 | 
| #137800 | Glioma susceptibility 1; glm1 | O75874 | 
| #605130 | Hairy elbows, short stature, facial dysmorphism, and developmental delay | Q03164 | 
| #610140 | Heart-hand syndrome, slovenian type | P02545 | 
| #176670 | Hutchinson-gilford progeria syndrome; hgps | P02545 | 
| #151660 | Lipodystrophy, familial partial, type 2; fpld2 | P02545 | 
| #248370 | Mandibuloacral dysplasia with type a lipodystrophy; mada | P02545 | 
| #613205 | Muscular dystrophy, congenital, lmna-related | P02545 | 
| #159001 | Muscular dystrophy, limb-girdle, type 1b; lgmd1b | P02545 | 
| #160900 | Myotonic dystrophy 1; dm1 | Q9NR56 | 
| #260540 | Parkinson-dementia syndrome | P10636 | 
| #172700 | Pick disease of brain | P10636 | 
| #275210 | Restrictive dermopathy, lethal | P02545 | 
| #601104 | Supranuclear palsy, progressive, 1; psnp1 | P10636 | 
| #277700 | Werner syndrome; wrn | Q14191 | 
| KEGG | name | UniProt | 
|---|---|---|
| H00264 | Charcot-Marie-Tooth disease (CMT) | P02545
                            (related) | 
| H00294 | Dilated cardiomyopathy (DCM) | P02545
                            (related) | 
| H00420 | Familial partial lipodystrophy (FPL) | P02545
                            (related) | 
| H00563 | Emery-Dreifuss muscular dystrophy | P02545
                            (related) | 
| H00590 | Congenital muscular dystrophies (CMD/MDC) | P02545
                            (related) | 
| H00593 | Limb-girdle muscular dystrophy (LGMD) | P02545
                            (related) | 
| H00601 | Hutchinson-Gilford progeria syndrome | P02545
                            (related) | 
| H00663 | Restrictive dermopathy | P02545
                            (related) | 
| H00665 | Mandibuloacral dysplasia | P02545
                            (related) | 
| H01216 | Left ventricular noncompaction (LVNC) | P02545
                            (related) | 
| H00058 | Amyotrophic lateral sclerosis (ALS) | P10636
                            (related) | 
| H00077 | Progressive supranuclear palsy (PSP) | P10636
                            (related) | 
| H00078 | Frontotemporal lobar degeneration (FTLD) | P10636
                            (related) | 
| H00001 | Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) | Q03164
                            (related) Q03164 (marker) | 
| H00002 | Acute lymphoblastic leukemia (ALL) (precursor T lymphoblastic leukemia) | Q03164
                            (related) | 
| H00296 | Defects in RecQ helicases | Q14191
                            (related) |