Cocculus pendulus (Forsk.) Diels

• Index
• Plant Species
• Metabolite list (31)
• Human Protein
  / Gene in interactions
• Related Diseases

Species

KNApSAcK Entry

Organism name	Cocculus pendulus (Forsk.) Diels
Genus	Cocculus
Family	Menispermaceae
Kingdom	Plantae

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NCBI taxonomy

Entry

Linked NCBI taxonomy name	Cocculus
Linked NCBI taxonomy ID	13440
Linked level	genus

Family

Family in NCBI taxonomy	Menispermaceae
ID	3455

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy	Viridiplantae
ID	33090

Plant class

Plant class	eudicotyledons
ID	71240

Metabolite list (31)

KNApSAcK ID	name	ChEMBL link	CTD link	# of proteins in ChEMBL interaction / related OMIM / related KEGG DISEASE	# of genes in CTD interaction / related diseases	KCF-S cluster	phytochemical cluster	figure
C00025633	(+)-1,2-Dehydro-2'-nortelobine / (+)-1',2'-Didehydro-2-nortelobine	CHEMBL505958				No. 10	No. 4
C00025634	1,2-Dehydroapateline / (+)-1,2-Dehydroapateline	CHEMBL390616				No. 10	No. 4
C00025635	(+)-1,2-Dehydrokohatamine					No. 10	No. 4
C00025636	(+)-1,2-Dehydrokohatine					No. 10	No. 4
C00025644	(+)-5'-Hydroxytelobine					No. 10	No. 4
C00025650	Cheratamine / (+)-Cheratamine					No. 10	No. 4
C00025653	Efirine / Cocsulin / (+)-Efirine / Trigilletine / (+)-Cocsuline / (+)-Trigilletine	CHEMBL447886 CHEMBL2063766				No. 10	No. 4
C00025663	Kohatamine / (+)-Kohatamine					No. 10	No. 4
C00025664	Kohatine / (+)-Kohatine / 5-Hydroxy-(+)-cocsoline					No. 10	No. 4
C00025665	Kurramine / (+)-Kurramine / O-Demethyl-1,2-dehydroapateline					No. 10	No. 4
C00025673	1'-Epicocsuline / N-Methylapateline / (+)-N-Methylapateline	CHEMBL447886 CHEMBL2063766				No. 10	No. 4
C00025677	(+)-Norpenduline / 2-Demethylpenduline	CHEMBL510273				No. 10	No. 4
C00025678	O,O-Dimethylcocsulinine / (+)-O,O-Dimethylcocsulinine					No. 10	No. 4
C00025682	Pendilinine / (+)-Pendilinine / O-Methylpendine / N2-Demethyl-O,O-dimethylpendulinine / O,O-Dimethyl-2'-N-demethylpendulinine					No. 10	No. 4
C00025683	Penduline / (+)-Penduline	CHEMBL504323 CHEMBL507540 CHEMBL1198334		4 / 3 / 4		No. 10	No. 4
C00025986	O-Methylcocsulinine					No. 10	No. 4
C00025686	(+)-Siddiquine					No. 10	No. 4
C00025689	Tricordatine / (+)-Tricordatine	CHEMBL443597				No. 10	No. 4
C00025753	1'-Epikohatine / 5'-Hydroxyapateline / (+)-5-Hydroxyapateline					No. 10	No. 4
C00026008	Pendine / (+)-Pendine					No. 10	No. 4
C00025815	Cocsilinine / N,N'-Didemethylcocsulinine					No. 10	No. 4
C00025816	Cocsoline / (+)-Cocsoline / 2'-Demethylcocsuline					No. 10	No. 4
C00025817	Cocsulinine					No. 10	No. 4
C00025914	Isotrilobin / Homotrilobin / Homotrilobine / (+)-Isotrilobine / N,O-Dimethylcocsoline	CHEMBL503241 CHEMBL448550				No. 10	No. 4
C00025938	Menisarine / (+)-Menisarine					No. 10	No. 4
C00025965	Nortrilobine / N2'-Demethyltrilobine					No. 10	No. 4
C00025685	(+)-Siddiquamine					No. 10	No. 4
C00026144	Sinactine / Tetrahydroepiberberine					No. 37	No. 4
C00025812	Coclaurine / (S)-Coclaurine / (-)-Coclaurine	CHEMBL256448 CHEMBL453291 CHEMBL446211	C004690	8 / 17 / 10		No. 253	No. 4
C00026019	Punjabine / (-)-Punjabine					No. 815
C00026101	(+)-Ophiocarpinone					No. 820	No. 4

Human Protein / Gene in interactions

12 ChEMBL Protein in interactions

accession	description	class description	KNApSAcK metabolite in interactions	# of diseases (OMIM / KEGG)
P14618	Pyruvate kinase PKM	Enzyme	C00025812	0 / 0
P04062	Glucosylceramidase	Enzyme	C00025812	6 / 4
P54750	Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A	PDE_1A	C00025683	0 / 0
O15296	Arachidonate 15-lipoxygenase B	Enzyme	C00025683	0 / 0
O75496	Geminin	Unclassified protein	C00025812	0 / 0
P63092	Guanine nucleotide-binding protein G(s) subunit alpha isoforms short	Other membrane protein	C00025812	7 / 3
Q99714	3-hydroxyacyl-CoA dehydrogenase type-2	Enzyme	C00025683	3 / 3
P08684	Cytochrome P450 3A4	Cytochrome P450 3A4	C00025683	0 / 1
P10636	Microtubule-associated protein tau	Unclassified protein	C00025812	4 / 3
B2RXH2	Lysine-specific demethylase 4E	Enzyme	C00025812	0 / 0
Q96KQ7	Histone-lysine N-methyltransferase EHMT2	Enzyme	C00025812	0 / 0
O94925	Glutaminase kidney isoform, mitochondrial	Enzyme	C00025812	0 / 0

Related Diseases

Diseases related to proteins in ChEMBL interactions